Best Large Grants for Nonprofit Organizations

The Sarasota County Foundation, established in 1958, aims to facilitate charitable donations for various purposes within Sarasota County. It provides grants to organizations that support educational, cultural, health, and humanitarian initiatives. Eligible organizations must be 501(c)(3) exempt, while the foundation typically does not fund endowments, travel, or completed projects. The foundation emphasizes support for local services, ensuring that its contributions enhance the community's welfare.

The Leon M. Seidel Memorial Trust Fund Grant supports charities in Bordentown, NJ. Established in 1967, it aims to benefit local residents through various charitable causes, including arts, education, health, and human services. To be eligible, organizations must be 501(c)(3) exempt. Applications are accepted year-round, with a submission deadline of April 1 for annual review. This grant promotes community welfare and addresses diverse needs.

The Parsons Area Community Foundation offers annual competitive grants aimed at improving the quality of life in the greater Parsons area. Nonprofits, schools, and government entities within a 25-mile radius can apply for funding between December 15 and January 31. The PACF Board evaluates applications, with decisions announced each April. Organizations receiving funds must submit project completion reports. This initiative fosters charitable giving and addresses community needs effectively.

The Tom and Frances Leach Foundation is dedicated to fostering healthy, thriving communities by awarding grants to nonprofit organizations. Their focus areas include education, health, human services, and arts & humanities, particularly in the Bismarck-Mandan and Western North Dakota regions. The foundation aims to support initiatives that promote educational opportunities, enhance healthcare access, improve quality of life, and preserve artistic endeavors, ensuring transformative impacts on local populations.

The Industrial Ties Research Subprogram (ITRS) with Proof-of-Concept/Prototyping Initiative, managed by the Louisiana Board of Regents, aims to bolster the state's economy by supporting research with strong private or federal funding links. This initiative facilitates technology transfer and commercialization of innovative ideas, aligning research projects with the growth of new or existing Louisiana businesses. By fostering collaboration between academia and industry, ITRS plays a crucial role in advancing economic development in Louisiana.

The Jones County Community Foundation Grant supports projects that enhance the quality of life for residents of Jones County, Iowa. With a maximum grant request of $25,000, the foundation prioritizes initiatives that improve economic well-being, educational opportunities, health, tourism, community heritage, and conservation. Eligible organizations must provide services within the county and can include nonprofits, public institutions, or charitable organizations. Collaborative projects are encouraged, and a minimum cash match of 25% is required.

Kansas Housing Resources Corporation

Kansas Housing Resources Corporation (KHRC) is a self-supporting, nonprofit, public corporation that serves as the primary administrator of federal housing programs for the state of Kansas. KHRC delivers solutions to those who are working to end the housing crisis in Kansas. The corporation’s vision can only be achieved when all Kansans have the support and resources they need to achieve their goals, no matter where they are in their housing journey.

CSBG Discretionary Grant

Kansas Housing Resources Corporation (KHRC) establishes guidelines for the awarding of discretionary grants as authorized by the Kansas Community Services Block Grant (CSBG). The primary intended use of the grant funds awarded to Kansas and to subgrantees is “to provide assistance to local communities in Kansas, working through a network of Community Action Agencies and other neighborhood-based organizations, for the reduction of poverty, the revitalization of low-income communities, and the empowerment of low-income families and individuals in rural and urban areas to become fully self-sufficient.”

CSBG Purpose and Goals

• Promoting maximum participation of people and communities with low-income
• Leveraging resources of other anti-poverty programs
• Strengthening community capabilities for planning or coordinating resources for local needs and conditions of poverty
• Using innovative approaches to address causes and conditions of poverty
• Measuring impact to ensure accountability and ongoing data-driven quality improvement 

As outlined with the FFY 2025-2026 CSBG State Plan, this RFP seeks proposals for: 1) Innovative Programs/Activities or 2) Training/Technical Assistance

Applicants are advised that direct services funded by CSBG are restricted to Kansas residents. with household incomes that fall at or below 200 percent of the Federal Poverty Guidelines

Training/Technical Assistance Projects

For the purposes of this funding opportunity, “training and/or technical assistance” examples include:

• Community-Based Interventions — Understanding community-level work/management; designing an effective approach, effective strategies, and relevant measures of success.
• Identifying and Sharing Best Practices — Innovative projects/programs using CSBG resources; leveraging other public/private resources; more effective use of economic development dollars; the bundling of services
• Serving Underserved Areas — Strategies for working in rural areas or communities with limited community services
• Multigenerational Approaches for Addressing Poverty — Coordinated approaches to collaborating with parents, other caregivers, and children.
• Relationship Building/Partnering — Among State CSBG offices and other State Agencies and Programs to share data and resources.
• Board Governance — Ongoing training to support active community input through Tripartite Boards including families of low-income.
• Leveraging Public/Private Resources — Coordinating multiple resources to support community services and strategies
• Leadership Development — Succession planning and mentoring, leadership academies 

The Foundation

The Daniel & Pamella DeVos Foundation’s purpose is to build strong, healthy communities by investing in the arts, education, and community well-being.

Our purpose is to build strong, healthy communities by investing in organizations that positively impact our culture.

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The Daniel & Pamella DeVos Foundation receives hundreds of requests each year from worthy organizations.

Due to the high volume of requests, the foundation primarily focuses its support on partners closely aligned with our three areas of focus and largely serves the greater Grand Rapids community. Requests can be submitted at any time. They are reviewed on a rolling basis, and the process generally takes three to four months from application submission to notification.

The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.

The W R Berkley Corporation Charitable Grant Program supports local 501(c)(3) organizations in Central Iowa, SW Minnesota, and Eastern Nebraska. With a focus on health, community betterment, youth development, education, and food insecurity, grants are awarded twice a year. There are no limitations on request sizes, but only one grant per organization is accepted annually. Funding decisions prioritize organizations with a proven track record of efficiency and success in serving their communities.

The Environmental Response Fund (ERF) Grant Program in Hennepin County provides essential funding for the assessment and cleanup of contaminated sites. It prioritizes projects that address significant contamination, demonstrate readiness, and support public development and affordable housing initiatives. Eligible applicants include municipalities and nonprofit organizations. This initiative promotes economic development and sustainable practices, ensuring healthier communities while tackling environmental challenges.

The Norfolk Southern In-Kind Donation Grant supports organizations seeking physical donations of materials that align with their focus areas, including safety, sustainability, workforce development, and thriving communities. This grant is available year-round, with no application deadline. Recipients must be located within Norfolk Southern territory and are encouraged to apply for resources that will enhance their community projects and initiatives, fostering growth and resilience.

The Vitality Fund-Growth Fund, managed by the District of Columbia's Office of the Deputy Mayor for Planning and Economic Development, aims to support local entrepreneurs and small businesses. By offering grants to those establishing or expanding operations in the central business district, the program seeks to create jobs and enhance economic vitality in the area. With a total funding of $551,131, this initiative is integral to fostering inclusive prosperity and economic growth in the District.

The Pat and John MacTavish Fund, established in 2007 by John Mac Tavish in memory of his wife Pat, provides scholarships aimed at encouraging young women to pursue higher education in the hard sciences. Awarded by the Grand Haven Area Community Foundation, scholarships are competitive and based on criteria such as financial need and academic achievement. Applicants from Northern Ottawa County or specific school districts are eligible. The fund emphasizes the importance of education in fields such as math, chemistry, and computer science.

The PLTW Gateway Program Expansion grant, funded by Huber in partnership with Project Lead The Way Inc., offers $10,000 to public schools aiming to enhance their existing PLTW Gateway programs for the 2026-2027 academic year. Eligible schools can use the funds for adding new units, increasing class periods, or training additional teachers. Annual reports and surveys are required to assess the program's impact and effectiveness.

The Suffolk Foundation's Community Impact Grants Program supports nonprofit organizations in Suffolk and Western Tidewater, Virginia, focusing on local projects in health, education, arts, and more. Grants prioritize organizations with strong local presence and leadership, funding direct project costs to enhance community impact. Eligible applicants include tax-exempt public charities serving residents in these areas. Exclusions apply for non-tax-exempt entities, individuals, and projects outside the service area, ensuring funds directly benefit the community.

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

Microsoft Disability Scholarship

This scholarship supports high school seniors living with a disability defined by WHO (World Health Organization — an impairment in a person’s body structure or function, or mental functioning (visual, hearing, mobility, cognitive, speech, or other disability). Eligible applicants must plan to study Engineering, Computer Sciences, Computer Information Systems, Law, Business (including Paralegal, Pre-Law, Finance, Business Administration, or Marketing) at an accredited two- or four-year college, university, or vocational-technical school. This scholarship is a $5,000 award with up to eight (8) scholarships granted.

About

The Advancing Communities grant program helps communities across Nebraska and southwest Iowa develop or enhance spaces that are inviting to all citizens, enabling connection through social, recreational, historical and civic engagement. By supporting capital projects that make great community assets — from libraries and youth rec centers to parks, trails, museums and more — we encourage our neighbors to get out and explore.

Advancing Communities Grant

Projects for consideration should align with the following themes:

• Shared spaces such as libraries, parks, trails and community centers — that encourage engagement and make towns more vibrant places to live, work and gather.
• Innovative ideas and forward-thinking approaches that engage multiple generations, introduce new ideas or bring fresh energy into existing community spaces.
• Community-led efforts, including partnerships among public, private and nonprofit sectors, with priority given to initiatives that demonstrate collaboration, local investment and community-driven vision.
• Sustainable, ready-to-launch projects that have secured at least 60% of their total funding and show clear plans for long-term maintenance, sustainability and measurable community benefit.

Grant amounts:

Applicants may request up to $250,000 for one time capital support.

Deadlines:

Applications for this program can be submitted at any time.

The JRCT Sustainable Future Grant Program aims to support innovative projects addressing climate change and social injustice. It prioritizes funding for organizations that tackle root causes of conflict, promote sustainable practices, and amplify marginalized voices. The trust is particularly interested in proposals that foster community power, challenge economic inequalities, and develop alternative models to consumerism. With a focus on long-term impact, JRCT encourages grassroots initiatives that engage diverse communities in creating systemic change.

The City of Richland's Community Development Block Grant program provides essential funding to support affordable housing and community development initiatives for low- and moderate-income residents. With an anticipated annual grant of $295,000 over five years (2025-2029), this program focuses on public services, construction of public facilities, and rehabilitation of structures. The funding strategy is outlined in a Consolidated Plan developed through community consultation, ensuring that local needs are met effectively.

The Mavs Foundation, affiliated with the Dallas Mavericks, provides grants to empower youth, women, and families in North Texas. Since 1996, it has awarded over $11 million to nonprofits, focusing on safe spaces for play and learning. The Foundation's initiatives include $50,000 grants for operational support, refurbishing basketball courts, and establishing Reading and Learning Centers to enhance education and job training. Organizations must meet specific eligibility criteria, including 501(c)(3) status and a minimum annual budget.

The PLTW Gateway grant supports public schools in offering innovative STEM education. Grantees must provide at least one PLTW Gateway unit during the 2026-2027 academic year, with an additional unit each subsequent year. The total grant award is $20,000, distributed in two installments. Grantees are required to submit annual reports and assist in student and teacher surveys to ensure ongoing program improvement. Eligible districts span several states, including Arkansas, Georgia, and Texas.

The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs to enhance equitable learning environments. Grants of up to $500,000 will support projects addressing systemic barriers, promoting effective practices, and ensuring seamless transitions from MSIs to advanced degrees in various STEM fields. The initiative seeks to create lasting impacts on student access and success in graduate education.

The Alfred P. Sloan Foundation's initiative, "Creating Equitable Pathways to STEM Graduate Education: Seed," aims to enhance graduate education access for students from Minority Serving Institutions (MSIs). The program provides grants of up to $500,000 to foster partnerships between MSIs and various higher education institutions. Projects should focus on overcoming barriers to success in graduate studies, including recruitment and admission processes, thereby promoting equitable learning environments in STEM fields.

The Alfred P. Sloan Foundation's Creating Equitable Pathways to STEM Graduate Education initiative aims to foster partnerships between Minority Serving Institutions (MSIs) and graduate programs. By addressing barriers in graduate education, the initiative seeks to promote equitable learning environments. Planning grants will support collaborations that assess needs and develop systemic changes to enhance pathways for students in STEM fields, ensuring that all students can thrive in their academic pursuits.

The Harry John Erbe Charitable Trust provides grants to tax-exempt organizations in support of charitable, religious, scientific, literary, and educational initiatives. Focused primarily on organizations in Pennsylvania, particularly Harrisburg, the trust emphasizes areas such as arts, education, health, and human services. Eligible groups must comply with Section 501(c)(3) of the Internal Revenue Code. This funding opportunity aims to enhance community services and promote cultural and educational development.

The Community Food Co-op invites applications for donations and sponsorships to support local initiatives in Whatcom County. Our mission is to foster cooperative ownership and promote community well-being through quality products and education. We prioritize funding requests that align with our strategic goals, ensuring that our contributions effectively enhance community engagement and sustainable practices.