Best Large Grants for Nonprofit Organizations

The Bonnycastle Fellowship for Wetland and Waterfowl Research supports graduate students in advancing conservation efforts. Offered by Ducks Unlimited, this fellowship provides up to $17,000 annually for research and personal support. The fellowship emphasizes the importance of research originality, ecological contributions, and feasibility. It is open to all North American graduate students, with a preference for doctoral candidates. The award is renewable for PhD students up to two years, and once for Master's students, contingent on satisfactory progress.

The Municipal Flood Control Grant Program, offered by the Wisconsin Department of Natural Resources, aims to assist local governments in managing flood risks. It provides funding for property acquisition, floodproofing, and flood control structure construction to enhance community resilience against flooding. This proactive approach addresses climate change impacts, promotes environmental sustainability, and aims to protect lives and property. Eligible projects focus on minimizing flood-related damages while maintaining natural watercourse functions.

The Chuckanut Health Foundation offers Community Grants to support critical health programs and infrastructure, with awards ranging from $2,600 to $26,000 annually. Established in 1983, the foundation focuses on fostering a healthy community by addressing health needs across six areas, including early childhood and health care access. Emphasizing community-led initiatives, these grants aim to empower local organizations to enhance the well-being of residents. Over $18 million has been awarded to over 280 non-profits since inception.

The NV Agricultural Conservation Easement Program (ACEP) aims to enhance agricultural viability and conservation values by limiting non-agricultural uses of eligible land. It includes Agricultural Land Easements (ALE) to protect croplands and Wetland Reserve Easements (WRE) to restore wetlands. This program supports landowners in preserving their land's agricultural integrity while promoting wildlife habitat through partnerships. Applications are accepted year-round, with future funding cycles available for late applicants.

The NE Agricultural Conservation Easement Program (ACEP) aims to protect agricultural viability by limiting nonagricultural land uses and enhancing conservation values. It includes Agricultural Land Easements (ALE) to safeguard croplands and Wetland Reserve Easements (WRE) for wetland restoration. Through partnerships, USDA's ACEP facilitates high-priority wetland protection and wildlife habitat improvement. Applications are accepted year-round, with automatic consideration for future funding cycles after ranking dates.

The ME Agricultural Conservation Easement Program (ACEP) supports the preservation of agricultural land by limiting nonagricultural uses and enhancing conservation values. It offers two components: Agricultural Land Easements (ALE) and Wetland Reserve Easements (WRE). ALE helps protect croplands and grasslands on working farms, while WRE focuses on restoring degraded wetlands. Additionally, the program includes the Wetland Reserve Enhancement Partnership (WREP) to improve wildlife habitat through collaborative efforts.

Context and Background

The Commonwealth of Kentucky has been awarded funding through the Centers for Medicare & Medicaid Services (CMS) Rural Health Transformation Fund (RHTF). This investment will empower Kentucky to launch and implement its Rural Health Transformation Plan (RHTP), a community-driven strategy to expand access and improve health outcomes for rural residents across the Commonwealth1 .

Our Plan

Kentucky’s RHTP launches five interrelated initiatives designed to build rural health infrastructure and provide sustainable, long-term improvements. This plan directly supports Kentucky’s rural counties while advancing statewide impact through innovation, technology-enabled care and strengthened workforce recruitment pipelines for both clinical and non-clinical staff. This strategy will help build a resilient, integrated and technology-forward health system across the Commonwealth.

• Rural Community Hubs for Chronic Care Innovation:
  • Establishes local “hub-and-spoke” collaboratives focused on obesity and diabetes prevention and management.
  • These hubs will integrate nutrition, physical activity programs, and digital self-management tools.
• PoWERing Maternal and Infant Health:
  • Expands timely prenatal and postpartum care by deploying telehealth-enabled maternal care teams who will serve maternity-care deserts and high-risk regions, to help mothers and infants receive seamless, high-quality support.
• Rapid Response to Recovery (EmPATH Model):
  • Deploys technology-enabled crisis stabilization and mobile behavioral health response teams to connect individuals with community-based treatment and recovery supports.
• Rooted in Health:
  • Rural Dental Access: Increases access to preventive oral health services through expanded dental hygiene training programs, externships, and investment in Public Health Dental Hygiene (PHDH) teams in Local Health Districts (LHDs).
• Crisis to Care:
  • Integrated Emergency Medical Services (EMS) Response and Coordination: Enhances pre-hospital capacity and trauma coordination through treat-in-place protocols, improved data connectivity and workforce training for rural EMS providers. 

The Land, Health, Community Grant Program, formerly known as Aspiramos Juntos, focuses on fostering holistically healthy communities in the Chicago region. Funded by the Lumpkin Family Foundation, this grant supports projects that promote physical activity, access to healthy food, and mental wellness for youth. Priority is given to grassroots organizations with budgets under $500,000 that are deeply connected to their communities. Special funding opportunities include grants for community gardens and inspiring collaborative projects up to $10,000.

Iowa Economic Development Authority

Mission

Strengthen economic and community vitality by building partnerships and leveraging resources to make Iowa the choice for people and business. Through two main divisions – business development and community development – IEDA administers several state and federal programs to meet its goals of assisting individuals, communities and businesses. IEDA works to achieve its mission and goals to benefit Iowans while maintaining a high level of transparency. 

CDBG Planning Grants

Approximately $60,522 in federal Community Development Block Grant (CDBG) funds are available to cities and counties through the state of Iowa’s Planning Grants Program. All incorporated cities and all counties in the State, except those designated as HUD entitlement areas, are eligible to apply for and receive funds under this program.

The Planning Grants Program allows communities to seek funding for three types of planning tools: Capital Improvement Plans, Asset Management Plans, and Historic District Surveys. Each plan can help communities understand their needs and create long-term strategies for protecting public health, strengthening economies, and sustaining critical infrastructure. These plans allow communities to best steward public, cultural, and historical resources and become more resilient and fiscally stable for generations to come.

Applicants must demonstrate at the time of application that they have, at minimum, a dollar-for-dollar match to the requested award amount.

The Planning Grant Program will not have a HUD National Objective; however, plans developed with CDBG funds must state how they will develop future CDBG projects.  

CFR 200 Audit Requirements

CDBG contracts may be subject to audit. Federal Code (2 CFR 200) requires that recipients that expend $750,000 or more in federal funds within a fiscal year must have a single or program specific audit. When budgeting for CDBG funds, applicants should be aware of these audit requirements:

• For recipients of $750,000 or more in federal funds received from more than one source of federal funding, an organization-wide audit must be conducted in accordance with federal requirements outlined in 2 CFR 200.514
• For recipients of $750,000 or more in federal funds received from a single source, a project audit, targeting only transactions dealing specifically with the project, may be performed in lieu of an organization-wide audit.

Communities should consult with their accountants regarding the applicability of an audit and audit requirements.

Audit costs are a CDBG-eligible expense. Organization-wide audits can be paid with CDBG funds proportional to the amount of all other funds included in the audit. The total cost of a project audit can be paid with CDBG funds.

The RBHA Regions Rural Behavioral Health Access program aims to enhance mental health services in Stark and Marshall counties. It focuses on crisis intervention, case management, and community outreach, employing two full-time mental health professionals. The program also provides training for educators and first responders to better identify mental health needs, while promoting awareness through community events. This initiative addresses systemic inequities, fostering inclusivity and diversity in service provision.

The Agricultural Conservation Easement Program (ACEP) supports the protection of agricultural land by limiting non-agricultural use, ensuring the conservation of vital resources. It offers Agricultural Land Easements (ALE) and Wetland Reserve Easements (WRE) to safeguard croplands, grasslands, and wetlands. Through financial assistance, the program enhances agricultural viability, promotes environmental quality, and fosters local partnerships for sustainable land management. Eligible partners include tribes, governments, and organizations dedicated to farmland preservation.

The Sunflower Grant supports grassroots organizations in Oregon with funding ranging from $1,000 to $10,000, typically between $4,000 and $7,000 annually. This program aims to assist independent 501(c)(3) organizations focusing on local community needs. While the grant process is straightforward, competition has increased due to a rise in applications. Eligible applicants must have a fiscal year financial statement available at the time of application, and the grants are intended for general operating support.

The Rose Grant is a competitive funding opportunity aimed at supporting Oregon-based nonprofits with operating budgets over $250,000. Grants typically range from $25,000 to $35,000 annually, with possible awards between $10,000 and $75,000. Organizations are encouraged to demonstrate a commitment to diversity and financial readiness. The grant application is shared with the Daffodil Grant program, and funding decisions are expected within 3-4 months after the application period closes.

The Tele-Behavioral Health Grant in Wisconsin aims to enhance access to tele-behavioral health services by reducing technological and geographical barriers. It seeks to support underserved populations, ensuring they receive necessary mental health care. By partnering with non-traditional sites, such as schools and community centers, the grant facilitates innovative access hubs. Funding will assist providers in acquiring technology and improving internet services, ultimately fostering continuity of care for individuals who face challenges accessing traditional behavioral health resources.

The Daffodil Grant is a highly competitive grant program aimed at supporting impactful organizations in Oregon. With funding typically ranging from $100,000 to $125,000 per year, it provides opportunities for multi-year commitments. Eligible applicants must demonstrate a commitment to diversity, equity, and inclusion, as well as financial stability. This program prioritizes organizations aligned with its mission and values, ensuring meaningful investments in the community. Applications are assessed rigorously, with funding decisions expected within 3-4 months.

The Zinnia Grant is a competitive funding opportunity aimed at making a significant impact in Oregon organizations. It typically awards between $250,000 and $350,000 annually for a three-year term. Eligible applicants must have an operating budget over $1M and a proven track record of previous grants. This grant emphasizes a commitment to equity and is designed to streamline the application process for organizations aligned with the foundation's mission.

The Capital Fund is an innovative grant program aimed at supporting capital campaigns for renovations or new projects. Offering competitive contributions ranging from $15,000 to $50,000, it prioritizes applicants with a proven track record of completed grants and projects located in Oregon. The fund encourages organizations to showcase their commitment to diversity and inclusion while also addressing pressing community needs. As this program evolves, it aims to better serve its partners and adapt to the changing landscape of funding.

The FL Agricultural Conservation Easement Program (ACEP) focuses on protecting agricultural viability and conservation values by limiting nonagricultural uses of eligible lands. It includes Agricultural Land Easements (ALE) to safeguard working farms and Wetland Reserve Easements (WRE) for restoring degraded wetlands. Additionally, ACEP collaborates with partners through the Wetland Reserve Enhancement Partnership (WREP) to enhance wetland conservation and wildlife habitats, ensuring sustainable agricultural practices across Florida.

The Pinellas Community Foundation's PCF Operating Grants provide essential two-year funding to nonprofits, enabling them to address core operational costs such as staffing, infrastructure, and outreach. These flexible, unrestricted grants empower organizations to prioritize their unique needs, ensuring that vital community services continue uninterrupted. With a focus on improving health, enhancing quality of life, advancing education, and promoting arts and culture, these grants align with the foundation's commitment to supporting diverse community initiatives.

The Peter Buck Postdoctoral Fellowship Program, established in 2011, offers multi-year fellowships for postdoctoral scholars to conduct independent research at the National Museum of Natural History (NMNH). Open to international applicants, it aims to enhance the scientific community by training future scientists and promoting innovative ideas. The fellowship includes a stipend of $62,000 annually, along with allowances for research, health insurance, and relocation. Applicants must have a recent PhD and be fluent in English.

SSUS State Opioid Grant shall be used to fund direct services for Core Harm Reduction, Harm Reduction Health, Overdose Prevention & Response Innovation, and planning activities for Capital Improvements to clients with behaviors that make them vulnerable to HIV/STD transmission as a result of injection drug use and support harm reduction and overdose prevention services at syringe access locations, harm reduction centers and county health departments.  This opportunity is limited to entities who were funded under DHSTS Opioid 2026 & DHSTS Opioid Expansion 2026. 

About Us

The governing board of the Mississippi Department of Mental Health is composed of nine members appointed by the Governor of Mississippi and confirmed by the State Senate. Members’ terms are staggered to ensure continuity of quality care and professional oversight of services. By statute, the nine-member board is composed of a physician, a psychiatrist, a clinical psychologist, a social worker with experience in the field of mental health, and one citizen representative from each of Mississippi’s five congressional districts (as existed in 1974).

Behavioral Health FY27 - Level 3 Low Intensity Residential Services Program (PPWMDC)

Residential Services is the highest community-based level of care for the treatment of substance use/addictive disorders. These levels of care provide a safe and stable group living environment where the individual can develop, practice, and demonstrate necessary recovery skills.

Collectively, all level 3 (3.1, 3.3, 3.5, and 3.7) program services provide residential care and comprehensive treatment services for adults and adolescents whose problems are so severe or are such that they cannot be cared for at home or in foster care and need the exclusive services provided by specialized facilities. Comprehensive services and activities may include diagnosis and psychological evaluation; alcohol and drug withdrawal management (detoxification) services; individual, family, and group therapy/ counseling; remedial education and GED preparation, vocational or pre-vocational training; training in activities of daily living; supervised recreational and social activities; case management; transportation; and referral to utilization of other services. 

• Level 3.1 Clinically Managed Low-Intensity Residential Services
• Level 3.3 Clinically Managed Population-Specific High-Intensity Residential Services
• Level 3.5 Clinically Managed High-Intensity Residential Services
• Level 3.7 Medically Monitored Intensive Inpatient Services

The Dubs Foundation's Responsive Grants Program aims to empower youth and promote healthy families through innovative projects in Southern Oregon and Northern California. Established in 1996, the foundation prioritizes rural organizations that foster an active outdoor lifestyle and support veterans' reintegration. With a focus on community improvement, the foundation encourages partnerships with nonprofits to enhance access to basic needs and inspire a love of wilderness areas. Applicants should review fluid guidelines regularly as the foundation prepares for its 20th anniversary.

The Chicago Board of Trade Foundation Grant offers funding to non-profit organizations in the Chicago area, focusing on initiatives that assist children, seniors, and individuals with disabilities. Eligible organizations must be 501(c)(3) tax-exempt and must not discriminate based on race, religion, or sexual orientation. Applications will be assessed based on program effectiveness, community impact, and organizational management. The foundation does not fund individuals, political candidates, or organizations without tax-exempt status.

Hawai‘i Sea Grant, part of a national network established in 1966, promotes the understanding and stewardship of marine and coastal resources through applied research, outreach, and education. The upcoming Biennial Research Competition focuses on critical research tracks including Island Sustainability and Resilience, Ocean Acidification, and Aquaculture. By supporting multidisciplinary initiatives, Hawai‘i Sea Grant aims to address pressing public concerns and disseminate valuable information across Hawai‘i and the Pacific.