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Explore global health grants supporting disease prevention, healthcare access, vaccination, maternal health, and global equity
32,000+
Available grants
$8.64B
Total funding
$6.3K
Median grant
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About PCORI
PCORI funds patient-centered comparative clinical effectiveness research (CER).
Our Mission
PCORI helps people make informed healthcare decisions, and improves healthcare delivery and outcomes, by producing and promoting high-integrity, evidence-based information that comes from research guided by patients, caregivers, and the broader healthcare community.
Broad Pragmatic Studies PCORI Funding
The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA), seeking to fund patient-centered comparative clinical effectiveness research (CER) projects.
Research Initiative Highlights
CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.
Special Areas of Emphasis
For Cycle 2 2026, PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAE) within the BPS funding opportunity. The purpose of identifying these SAEs is to encourage submissions to these areas, rather than limiting submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:
In PCORI-funded research, patients and other research partners are expected to meaningfully contribute their lived experience or professional expertise to ensure studies are patient-centered, relevant and useful for healthcare decision making. Applicants must address PCORI’s Foundational Expectations for Partnerships in Research — an evidence-based framework supported by tools and resources to guide effective engagement strategies. Applicants are also strongly encouraged to consider the inclusion of a broad range of patient-centered burdens and economic outcomes.
Broad Pragmatic Studies PFA: Category 1, Category 2 and Category 3 Study Specifications
PCORI will commit up to $120 million in direct costs through this funding opportunity. This funding opportunity contains three categories for funding:
The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Broad Pragmatic Studies (BPS) PCORI Funding Announcement (PFA) on Aug. 4, 2026, seeking to fund high-impact, patient-centered comparative clinical effectiveness research (CER) projects. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality applications.
Patient-centered CER compares at least two available health treatments, services or care delivery strategies. PCORI seeks proposals that compare clinical interventions (e.g., pharmacological and nonpharmacological treatments, screening and diagnostic approaches) and healthcare delivery system interventions (e.g., workforce, technologies, healthcare service delivery designs) to evaluate potential benefits and harms of different treatment and care delivery options, thus generating evidence that empowers patients, caregivers and the broader healthcare community with information to make informed choices that reflect their needs and preferences.
About the Montana Department of Commerce
Every day, staff at Commerce work alongside private industry and local organizations to create jobs, grow businesses, provide affordable housing and improve community infrastructure.
The economy of the Treasure State continues to grow and diversify. Studies rank Montana as the number one place in the country to start a business. Plus, our workforce has earned some of the highest rankings in both trade and technical skills by having one of the highest STEM (science, technology, engineering and mathematics) concentrations in the country.
Public and Community Facilities
Public and Community Facility Grants
Montana's CDBG Public and Community Facilities grants help local governments fund construction or rehabilitation of infrastructure and facilities that primarily benefit low- to moderate-income (LMI) Montanans, i.e. individuals earning less than 80% of the area median income. These projects can target LMI residents and provide direct benefits by improving or creating access to suitable living environments or necessary services, or these projects can provide an area-wide benefit to the entire community as long as at least 51% of the project’s beneficiaries are determined to be LMI.
Certain projects such as senior centers, food banks, homeless shelters, youth homes, or head start centers are presumed to serve a limited clientele that is primarily LMI. Therefore, determining exactly what percent of project beneficiaries qualify as LMI is not required. Other projects, such as a wastewater improvements or water treatment improvements provide benefits to the entire community and are considered to have area-wide benefit because both LMI and non-LMI residents are served. Therefore, applicants must document at least 51% of the project’s beneficiaries qualify as LMI for projects considered to have an area-wide benefit.
Major Grant Fund
Apply for $50,000 to $200,000 per year, renewable up to two times for a total of three years of funding. Funds may support health-related direct service delivery or advocacy efforts. New for 2026, Major Grant funds can also support evaluation projects.
Funding Principles
Projects funded by the Health Equity Fund should align with the following funding principles:
Improving health outcomes and access
for communities and populations experiencing the deepest and most persistent health and economic disparities in King County.
Actively addressing the issues of systemic, structural, and institutional barriers
including racism, sexism, homophobia, transphobia, income inequality, and other forms of oppression or discrimination that negatively impact healthcare delivery and health outcomes.
Partnering or collaborating with other organizations
to enhance the impact of addressing health disparities.
Building capacity and empowerment
for communities addressing health disparities.
Funding for service delivery is limited to King County. There are no geographic restrictions on the residence of clients served or advocacy efforts, as long as the program can demonstrate the use of funds addressing disparities in health among residents of the Puget Sound region (King, Snohomish, Pierce, and Kitsap counties).
Organizations may not receive two PHPDA grants in the same year for the same project. Applicants can request grant funds for a different project as long as the time period covered by funding ends by the new contract period.
Organizations may only submit one application.
Focus Areas
Specific populations are facing heightened threats to their safety, security, and access to care, and the organizations that support them are experiencing drastic funding cuts. Our Major Grant program aims to support these organizations who are facing disproportionate burdens to their wellbeing. This year, Major Grants will be limited to organizations with projects in one or more of these three focus areas:
Grants for global health fund initiatives that address health disparities, improve access to care, and promote wellness worldwide. The following grants empower nonprofits to combat diseases, support public health, and enhance healthcare systems globally.
Explore 8,000+ funding opportunities for global health initiatives, with $3.84B available. Instrumentl helps nonprofits find relevant funding, manage deadlines efficiently, and access insights to drive impactful global health programs.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for grants for Global Health?
Most grants are due in the first quarter.
Nonprofits who want to win global health grants include international health organizations, research institutions, and humanitarian groups working to improve health outcomes worldwide. These grants more than likely address global health fund initiatives that address disparities, improve access to health care, and promote global health awareness. Most grants will require you to have a 501(c)(3) status or a fiscal sponsor.
Grants in global health typically have the highest concentration of deadlines in Q1, with 28.0% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q4.
Global health grants are offered to nonprofit programs that focus on reducing health disparities, improving disease prevention, and expanding healthcare services in underserved regions. Funders also focus on empowering nonprofits that combat diseases, support public health, strengthen healthcare infrastructure, advance medical research, and support emergency response efforts. More than 6,000 funding opportunities are available, with more than $2.94 billion available in funding for nonprofit groups that address global health fund initiatives.
Funding for global health grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $37,500, while the average grant awarded is $734,409. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Of the more than $2.94 billion available, most funding for global grants come from private funders like the Wheeler Charitable Trust Grant, the Alabama Law Foundation, the American Journalism Project Inc., and the Cooke Foundation. In addition, there are also federal and state/local grants available through health departments and community service grants. Some key federal funders that provide funding for global health initiatives include the U.S. Department of Health and Human Services, the USDA, and the U.S. Department of Labor.
To improve grant success, nonprofits interested in global health grants should concentrate on all of these key areas:
For additional guidance, explore our step-by-step guide to crafting compelling grant proposals.
With more than 6,000 global health grant opportunities to sift through, Instrumentl simplifies the grant application process by helping you filter through the relevant funding opportunities, track deadlines, and analyze funder-giving patterns. Try using the platform's automated alerts so that you never miss a deadline. In addition, the detailed funder insights help organizations tailor their applications to align with grantor priorities for global health grants. Learn how NYU Langone saved significant time prioritizing their best-fit funding opportunities.