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Best Grants for HIV / AIDS
Get funding for HIV/AIDS prevention, treatment access, awareness campaigns, and support services for impacted communities
53
Available grants
$58.3M
Total funding
$650K
Median grant
53
grants
$58.3M
total
$650K
median
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Last updated: June 8, 2026. Next update: July 5, 2026.
Unspecified amount
Costco Wholesale Charitable Contributions
Rolling deadline
The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.
Costco Foundation
Up to US $15,000
DanPaul Foundation Grants
Rolling deadline
The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.
The Dan Paul Foundation
Up to US $300,000
Draper Richards Kaplan Foundation Grants
Rolling deadline
The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.
Draper Richards Kaplan Foundation
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Unspecified amount
Gilead North America Grants
Rolling deadline
Gilead North America Grants support community-informed programs that enhance healthcare for vulnerable populations. Grants are available for innovative projects addressing HIV, liver diseases, oncology, and inflammatory diseases. Applications are invited from tax-exempt nonprofits based in the U.S. who focus on health equity and community engagement. Gilead prioritizes funding for projects that demonstrate a strong capability to deliver impactful outcomes, helping to eliminate barriers to healthcare and improve access to essential services.
Gilead Sciences, Inc.
More than US $100,000
Hearst Foundation: Social Service Grant
Rolling deadline
The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.
William Randolph Hearst Foundation
Unspecified amount
LabCorp Charitable Foundation Grants
Rolling deadline
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Labcorp Charitable Foundation
Unspecified amount
Mapplethorpe Foundation: Photography Grant
Rolling deadline
The Robert Mapplethorpe Foundation, established in 1988, supports photography programs at museums and public institutions. It promotes photography's recognition alongside other art forms and contributes to HIV/AIDS medical research. Notably, it has funded major galleries and initiatives, donating significant collections to renowned museums. The Foundation aids curators in developing photography exhibitions and provides financial support for acquisitions, exhibitions, and publications, ensuring Mapplethorpe's artistic legacy endures.
Robert Mapplethorpe Foundation
More than US $50,000
Michael & Susan Dell Foundation Grants
Rolling deadline
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Michael & Susan Dell Foundation
Unspecified amount
Wells Fargo Community Giving
Rolling deadline
Wells Fargo Community Giving supports nonprofit organizations focusing on financial health, housing affordability, small business growth, and sustainability. The grant cycle runs from February to October, inviting organizations with 501(c)(3) status or equivalent to apply. Funding is prioritized for programs addressing critical community needs, while limited support is available for local initiatives like disaster relief and arts. Organizations must demonstrate fiscal stability and potential impact to be considered for funding.
Wells Fargo Foundation
Up to US $450,000
Pilot and Feasibility Studies in Preparation for Substance Use Prevention Trials (R34 Clinical Trial Optional) (351723)
Applications due Jun 16, 2026
The Pilot and Feasibility Studies (R34) grant opportunity invites research proposals aimed at developing and testing interventions to prevent substance use and its progression to misuse or disorder. This includes feasibility studies for new services and systems. The funding is provided by the US Department of Health & Human Services' NIH, with multiple deadlines for applications from 2024 to 2026, fostering innovation in substance use prevention research.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Unspecified amount
Kroger Foundation: Donation Request
Applications due Jun 26, 2026
The Kroger Foundation is dedicated to uplifting communities through significant charitable contributions, having donated over $1.9 billion in the past six years. Their focus on combating hunger through the Zero Hunger | Zero Waste initiative exemplifies their commitment to social impact. Annually, they provide over $300 million to nonprofit organizations aligned with their mission, promoting health, education, and disaster relief while fostering diversity and inclusion. This initiative reflects Kroger's belief that strong communities are a shared responsibility.
Kroger Co. Foundation
Unspecified amount
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional) (351433)
Applications due Jul 5, 2026
This funding opportunity seeks innovative research at the intersection of HIV and aging. It aims to enhance understanding of the biological, clinical, and socio-behavioral aspects of aging in the context of HIV. Additionally, it encourages the development of effective strategies for preventing and treating HIV, as well as managing HIV-related complications across diverse populations. Proposals must align with NIH's HIV/AIDS Research Priorities, ensuring relevance and impact in this critical field.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Up to US $2,499,995
National Cancer Institute & Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)
Applications due Jul 5, 2026
The National Cancer Institute is seeking proposals for early phase clinical trials focused on cancer diagnostics and therapeutics. The program encourages investigator-initiated trials related to various cancer research programs, including those for HIV and AIDS malignancies. Key deadlines for submissions range from February 2024 to October 2026, with letters of intent encouraged 30 days prior to proposals. This initiative aims to advance cancer treatment and improve patient outcomes through innovative research.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Up to US $499,999
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)
Applications due Jul 5, 2026
The National Cancer Institute invites research proposals for early phase clinical trials focusing on cancer diagnostics and therapies. This initiative emphasizes investigator-initiated trials relevant to specific research programs. Deadlines for applications range from February 2025 to January 2027, with optional Letters of Intent due 30 days prior to submission. This funding opportunity aims to enhance cancer treatment and diagnosis through innovative research projects.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
US $10,000 - US $40,000
AIDS United: Harm Reduction Futures Fund
Pre proposal due Aug 21, 2026
The AIDS United Harm Reduction Futures Fund aims to combat the HIV epidemic by supporting organizations that provide syringe services and harm reduction programs. This initiative focuses on reducing health disparities for people who use drugs, promoting community-driven solutions, and ensuring equitable access to health services. Grants ranging from $10,000 to $40,000 will support organizations led by and serving Black, Indigenous, and other People of Color, especially in underserved areas. Direct service applications are currently prioritized.
Aids United
Up to US $10,000
Cowles Charitable Trust Grant
Applications due Sep 1, 2026
The Cowles Charitable Trust Grant supports initiatives aligned with the philanthropic legacy of Gardner Cowles, Jr. Focused on education, social justice, health, and the arts, it favors organizations recognized as 501(c)(3) by the IRS. The Trust encourages applications for general operating support and seeks partnerships rather than being the sole funder. Notably, it considers applications from established partners and supports efforts in Downstate New York and South Florida, with a preference for diverse funding sources.
Cowles Charitable Trust
Unspecified amount
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional) (358076)
Applications due Sep 7, 2026
This funding opportunity invites innovative research focusing on the intersection of HIV and aging. It aims to enhance the understanding of biological, clinical, and socio-behavioral aspects of aging in the context of HIV infection and treatment. Researchers are encouraged to improve methods for testing, preventing, and treating HIV, as well as managing associated comorbidities across diverse populations. Proposals should align with NIH's HIV/AIDS Research Priorities to maximize impact and relevance.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Up to US $275,000
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional) (351432)
Applications due Sep 7, 2026
This funding opportunity invites innovative research at the intersection of HIV and aging, focusing on biological, clinical, and socio-behavioral aspects of aging among those living with HIV. Applicants are encouraged to enhance methodologies for testing, prevention, and treatment of HIV, as well as managing related comorbidities across diverse populations. Proposals should align with NIH's HIV/AIDS Research Priorities to advance understanding and improve health outcomes in this critical area.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Unspecified amount
Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
Applications due Sep 25, 2026
The Limited Competition NOFO aims to provide ongoing support for specific pathogen-free (SPF) macaque colonies that facilitate vital HIV/AIDS research. Only recipients funded under previous ORIP-supported SPF colony announcements are eligible to apply. These breeding colonies are crucial for maintaining SPF macaques, which are free from certain viruses that could jeopardize research outcomes. The project emphasizes the genetic characterization of macaques to enhance understanding of immune responses related to HIV and SIV.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Unspecified amount
Dudley T. Dougherty Foundation Grant
Applications due Oct 31, 2026
The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.
Dudley T Dougherty Foundation Inc
Unspecified amount
TJX Foundation Grants
Letter of inquiry due Oct 31, 2026
The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.
The Tjx Foundation Inc
Up to US $180,000
Mathilde Krim Fellowships in Biomedical Research
Pre proposal due Mar 19, 2027
The Mathilde Krim Fellowships in Biomedical Research, offered by amfAR, aim to support innovative postdoctoral researchers transitioning to independent careers in HIV/AIDS research. With a funding maximum of $180,000 over two years, these fellowships prioritize research that uncovers vital knowledge towards curing HIV. Eligible applicants must hold a recent doctorate, demonstrate research independence, and be affiliated with a nonprofit institution. This initiative reflects amfAR's commitment to ending the global AIDS epidemic through groundbreaking research.
The Foundation For Aids Research
Unspecified amount
O'Reilly Automotive Foundation Grant
Applications due Apr 15, 2027
The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.
O'Reilly Automotive Foundation Inc
US $30,000 - US $350,000
True Inspiration Awards
Applications due May 1, 2027
The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.
Chick Fil A Foundation Inc
Up to US $275,000
Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed) (358082)
Applications due Nov 16, 2027
This funding opportunity invites innovative pilot studies focused on biological, behavioral, and social mechanisms related to HIV pathogenesis, aligning with NIDDK's mission and NIH HIV/AIDS research priorities. Topics may include exploring pathophysiological mechanisms of HIV comorbidities and coinfections, understanding HIV reservoirs in relevant tissues, and examining social determinants affecting health outcomes. Applications are due by 5:00 PM local time of the applicant organization.
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Showing 25 of 53 results.
Sign up to see the full listGrants for HIV / AIDS Highlights
Grants for HIV / AIDS fund programs aimed at prevention, treatment, and support services for affected communities. The following grants empower nonprofits to provide education, healthcare access, and advocacy to combat the epidemic.
Search Instrumentl's HIV / AIDS Grants Database
Explore 53 funding opportunities for HIV / AIDS programs, with $58.3M in resources. Instrumentl provides nonprofits with tools for customized searches, deadline tracking, and insights to advance healthcare access and education.
Last updated: June 8, 2026. Next update: July 5, 2026.
Top Searched Grants for HIV / AIDS
Frequently asked questions
Nonprofits who want to win HIV/AIDS grants are usually organizations that focus on awareness, prevention, and treatment programs. They are likely to be nonprofits, community health organizations, research institutions, and advocacy groups focused on HIV/AIDS prevention, treatment, and support services for affected communities. Many funders prioritize initiatives that support at-risk populations, expand access to healthcare, and advance medical research. Many grants require applicants to be 501(c)(3) organizations and may prioritize those with established success in providing education, healthcare access, and advocacy.
Grants for HIV/AIDS typically have the highest concentration of deadlines in Q3, with 27.5% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q2.
HIV/AIDS grants are offered to nonprofit programs that focus on reducing the spread of HIV, improving patient care, and funding research for better treatments and potential cures. Funders seek to enhance education, reduce stigma, and support healthcare infrastructure for people living with HIV/AIDS. Less than 100 grants are available, with a little more than $40,000 in funding for nonprofit groups that address these key issues.
Funding for HIV/AIDS grants varies widely, with award amounts ranging from a minimum of $2,500 to a maximum of $15,000,000. Based on Instrumentl’s data, the median grant amount for this category is $650,000, while the average grant awarded is $2,009,606. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Most of the grants available for HIV/AIDS are from federal government entities, like the U.S. Department of Health and Human Services and the U.S. HHS: Health Resources and Services Adiministration (HRSA). Organizations such as the Elton John AIDS Foundation, the Bill & Melinda Gates Foundation, and private healthcare foundations like the Foster Foundation and The Elizabeth Taylor AIDS Foundation also provide funding for HIV/AIDS initiatives.
Because grants for HIV/AIDS are competitive, concentrate on all of these key areas:
- Align with funder priorities – Tailor proposals to match the funder’s mission in reducing the spread of HIV/AIDS and improving patient care, and outline clear health intervention strategies.
- Use measurable outcomes – Provide data that illustrates your program's impact on reducing HIV transmission.
- Build strategic partnerships – Collaborate with local health departments, hospitals, and advocacy networks.
- Develop a compelling narrative – Tell real stories of individuals with HIV/AIDS that have been helped by your work.
For additional guidance, explore our step-by-step guide to crafting compelling grant proposals.
Instrumentl has an intuitive platform that helps nonprofits looking for HIV/AIDS grants to find relevant funding opportunities in their specific communities. That way, you can use the platform to tailor your applications to align with grantor priorities and ensure the grant monies are helping those who need it most in your geographic area. See how the Los Angeles LGBT Center cut down weekly admin time from 2-4 hours to less than 30 minutes.
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