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Search Through Addiction and Substance Abuse Grants

Find grants for addiction treatment, prevention, and recovery. Get funding for rehab centers, education, opioid response, and substance abuse programs

200+ grants

$65.2M total

$99.8K median

200+
Available grants

$65.2M
Total funding amount

$99.8K
Median grant amount

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Last updated: May 4, 2026. Next update: June 7, 2026.

Rolling deadline

Unspecified amount

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

Rolling deadline

Up to US $15,000

The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.

Rolling deadline

Up to US $300,000

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

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Rolling deadline

Up to US $100,000

The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.

Rolling deadline

Unspecified amount

State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.

Rolling deadline

More than US $100,000

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Rolling deadline

Unspecified amount

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

Rolling deadline

Unspecified amount

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

Rolling deadline

Unspecified amount

Wells Fargo Community Giving supports nonprofit organizations focusing on financial health, housing affordability, small business growth, and sustainability. The grant cycle runs from February to October, inviting organizations with 501(c)(3) status or equivalent to apply. Funding is prioritized for programs addressing critical community needs, while limited support is available for local initiatives like disaster relief and arts. Organizations must demonstrate fiscal stability and potential impact to be considered for funding.

Applications due Jun 30, 2026

Unspecified amount

The Kroger Foundation is dedicated to uplifting communities through significant charitable contributions, having donated over $1.9 billion in the past six years. Their focus on combating hunger through the Zero Hunger | Zero Waste initiative exemplifies their commitment to social impact. Annually, they provide over $300 million to nonprofit organizations aligned with their mission, promoting health, education, and disaster relief while fostering diversity and inclusion. This initiative reflects Kroger's belief that strong communities are a shared responsibility.

Applications due Jul 1, 2026

Unspecified amount

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

Applications due Aug 1, 2026

Unspecified amount

The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.

Applications due Aug 6, 2026

Up to US $275,000

The Cutting-Edge Basic Research Awards (CEBRA) from the National Institute on Drug Abuse (NIDA) aim to support innovative research in substance use disorders (SUDs). This program encourages high-risk, high-impact projects that may not be represented in current research portfolios. Applicants are invited to develop revolutionary techniques or test significant hypotheses that could transform addiction research. Letters of Intent are encouraged and due 30 days prior to the proposal deadline.

Applications due Aug 31, 2026

US $5,000 - US $250,000

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

Applications due Sep 9, 2026

Up to US $275,000

The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.

Applications due Sep 25, 2026

More than US $50,000

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Applications due Oct 31, 2026

Unspecified amount

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

Applications due Oct 31, 2026

US $5,000 - US $20,000

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

Applications due Nov 1, 2026

US $5,000 - US $10,000

The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.

Applications due Feb 27, 2027

Approximately US $50,000

The Human Animal Bond Research Institute (HABRI) invites research proposals exploring the health benefits of human-animal interactions. This grant aims to fund studies that examine the positive impacts of pet ownership and animal-assisted interventions on human and animal health. Key areas of interest include mental and physical health, social isolation, and the welfare of diverse populations. Successful proposals will adhere to high standards of animal care and demonstrate actionable outcomes for policy and practice.

Applications due Mar 23, 2027

Unspecified amount

The Hansen Family Foundation Grant seeks to empower organizations that uphold the American values of life, liberty, and the pursuit of happiness. Focused on diverse causes like children, education, animals, environmental conservation, humanitarian efforts, and arts, the foundation is committed to supporting initiatives that create positive change. Eligible applicants must be 501(c)(3) nonprofits, while political campaigns and organizations with high budgets or overheads are ineligible. This grant fosters impactful contributions to society.

Applications due Apr 15, 2027

Unspecified amount

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

Showing 22 of 200+ results.

Addiction and Substance Abuse Grants Highlights

Addiction and substance abuse grants provide critical funding for nonprofits addressing prevention, treatment, and recovery efforts. These grants support programs focused on education, mental health services, and community outreach, helping to combat the devastating effects of addiction and improve individual and public health outcomes.

Search Instrumentl's Addiction and Substance Abuse Grants Database

Find 200+ active grants with over $65.2M available for nonprofits tackling addiction challenges. Explore private, corporate, and government funding options tailored to your mission. Track deadlines, gain funder insights, and grow your impact with Instrumentl's comprehensive tools.

Last updated: May 4, 2026. Next update: June 7, 2026.

Top Searched Addiction and Substance Abuse Grants

Addiction and Substance Abuse Grants from Private Funders

Addiction and Substance Abuse Grants over $20k

Addiction and Substance Abuse Grants for Projects & Programs

Addiction and Substance Abuse Grants from Government Funders

Grant Insights : Addiction and Substance Abuse Grants

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Addiction and Substance Abuse Grants grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Addiction and Substance Abuse Grants over $25K in average grant size

88 Addiction and Substance Abuse Grants over $50K in average grant size

26 Addiction and Substance Abuse Grants supporting general operating expenses

200+ Addiction and Substance Abuse Grants supporting programs / projects

500+ Grants on Instrumentl focused on Addiction & Substance Use Disorders

400+ Grants on Instrumentl focused on Disaster Relief / Humanitarian Aid

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Addiction and Substance Abuse grants?

Most grants are due in the first quarter.

27.6%

26.9%

26.3%

19.2%

Typical Funding Amounts

What's the typical grant amount funded for Addiction and Substance Abuse Grants?

Grants are most commonly $99,750.

$500 $500 Min.

$99,750 $99.8 K Median

$494,297 $494.3 K Average

$11,000,000 $11 M Max.

Frequently Asked Questions

What types of nonprofits can qualify for Addiction and Substance Abuse grants?

Nonprofits who want to win grants for addiction and substance abuse are usually organizations focused on prevention. They also likely provide treatment, harm reduction services, and recovery support. The funders offering these grants care about programs that serve at-risk populations. This includes low-income communities and individuals impacted by the opioid crisis. The grants you see will require your organization to have a 501(c)(3) charitable status.

Grants for addiction and substance abuse prevention typically have the highest concentration of deadlines in Q1, with 27.6% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q4.

Why are Addiction and Substance Abuse grants offered, and what do they aim to achieve?

Addiction and substance abuse grants are offered to nonprofit programs that focus on addiction prevention, harm reduction, and long-term recovery to oppose the detrimental effects of the disease on society. Over 200 grants are available, with more than $87.1 million in funding for nonprofit groups that address addiction challenges.

Funding for addiction and substance abuse grants varies widely, with award amounts ranging from a minimum of $500 to a maximum of $11,000,000. Based on Instrumentl’s data, the median grant amount for this category is $99,750, while the average grant awarded is $494,297. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Who typically funds Addiction and Substance Abuse grants?

Of the $87.1 million available, most comes from private funders. In addition, there are many federal and state/local government funders. Some of the key funders who support addiction prevention services are the US Department of Justice, followed by a lot of state-level organizations like the Kentucky Opioid Abatement Advisory Commission and other community health foundations. On the private side of grant funding, grantors include Inasmuch Foundation, Humana Foundation, and more.

What strategies can nonprofits use to improve their success rate for Addiction and Substance Abuse grants?

A carefully planned approach is needed in order to successfully win grants for substance abuse as well as addiction programs. Funders look for organizations that show a clear effect and align with the priorities of funders. These organizations also have strong community support. To greatly increase your chances of success, concentrate on all of these key areas.

Forge completely meaningful partnerships – Collaborate closely with all healthcare providers, community organizations, and fellow nonprofits to strengthen your proposal and show a greatly united effort.
Offer an exhaustive financial plan – Show responsible financial management and present a budget detailing how each and every grant dollar will be allocated.

Visit our resource for a complete, step-by-step guide on how to find and apply for many grants. Find grants for nonprofits with a guide.

How can Instrumentl simplify the grant application process for Addiction and Substance Abuse grants?

Instrumentl simplifies the grant application process by offering standards that helps nonprofits discover relevant funding opportunities and analyze funder-giving patterns. The platform's automated alerts ensure deadlines are never missed, while detailed funder insights help organizations modify their applications to align with grantor priorities. Discover how Oasis–A Haven for Women and Children cut their time spent on grant research by 83%.