Best Addiction and Substance Abuse Grants

Nonprofit and local government organizations providing education, health, public safety, or addiction-related services can seek funding for prevention, treatment, housing, arts, environmental, cultural, and other charitable programs. The Confederated Tribes of Siletz Indians provides grants to groups in eleven Oregon counties and Native American organizations across the U.S. addressing addiction and related community needs.

Nonprofit organizations, community councils, and municipal agencies in Tompkins County addressing addiction, substance use disorders, and related mental health or basic needs may be eligible for this two-year community impact funding. Grants from United Way of Tompkins County support programs in areas like mental health, crisis intervention, and marginalized communities that strengthen local prevention, treatment, and recovery efforts.

Nonprofit organizations providing addiction and substance use treatment or prevention programs in Mesa County, Colorado can apply for support from the Western Colorado Community Foundation’s Brownson Memorial Fund. Focused on substance abuse, alcoholism, and drug use disorders, this funding could help strengthen local prevention, treatment, and recovery services in the county.

Nonprofit 501(c)(3) organizations and fiscally sponsored projects serving Clark and Floyd counties in Indiana can seek capacity-building grants supporting governance, leadership, technology, evaluation, and strategic planning. Grants from Community Foundation of Southern Indiana, ranging from US $5,000 - US $25,000, may benefit organizations providing addiction and substance use disorder, mental health, and related community services.

Wisconsin 501(c)(3) nonprofits addressing addiction, substance use disorders, domestic violence, or broader health and wellness can seek project funding of US $3,000 - US $8,000. Grants from Green Bay Packers Foundation help eligible organizations run programs that fit the current year’s focus areas within its 2026–2029 funding cycle.

Research institutions and other eligible organizations in the U.S. territories and states can apply for National Institutes of Health funding to test SBIRT/P approaches for alcohol, tobacco, and other drug use in adults experiencing health disparities. Projects must prospectively evaluate screening, brief intervention, and referral models in partnership with healthcare and community settings, supporting addiction and substance use disorder efforts.

Nonprofits, faith-based organizations, and tax-exempt schools in Franklin County can apply for ADAMH Board of Franklin County’s mini-grants up to Up to US $5,000 to run community programs and events. Funding supports behavioral health awareness, prevention, stigma reduction, resilience, social connectedness, and diversity, equity, and inclusion, which may include addiction and substance use disorder initiatives.

Focused on community support and health services, Atkinson Foundation invites San Mateo County nonprofits to apply for grants up to Up to US $20,000. Eligible 501(c)(3) organizations under $10 million providing direct services, including alcoholism and drug use disorder treatment, mental/physical health care, and basic needs assistance, may benefit.

Organizations in Grays Harbor County addressing addiction, substance use, or related community needs can apply for Grays Harbor Community Foundation’s Quarterly Impact Grants, with awards up to US $5,000 for small, near-term projects. Programs focused on alcoholism, drug use disorder, prevention, or recovery services may benefit, with priority for funds used within two months.

Nonprofit and charitable organizations in Grays Harbor County can seek funding to start, expand, or sustain programs, equipment, or infrastructure. With a mission to improve quality of life, Grays Harbor Community Foundation provides US $5,000 - US $30,000 for efforts including substance abuse and alcoholism treatment, mental health services, crisis intervention, and related community wellness initiatives.

Nonprofits, schools, government units, and religious organizations serving Wicomico, Worcester, or Somerset Counties can seek funding for addiction, alcoholism, and drug use disorder programs, along with broader human services. Focused on community needs, Community Foundation of the Eastern Shore invites eligible organizations to submit a general Letter of Inquiry; requests submitted by the 15th receive decisions the following month.

Nonprofit organizations, public schools, and governmental agencies in Lapeer, Macomb, Oakland, and St. Clair counties can seek funding for education, health, and community programs, including youth and adult initiatives. Four County Community Foundation supports projects such as smoking and vaping prevention, substance use education, and related health and counseling efforts that directly benefit local residents.

Nonprofit 501(c)(3) organizations and government equivalents providing addiction prevention, treatment, or recovery services in Colorado can access funding through the Daniels Fund, with typical awards around Approximately US $75,000. Eligible programs address drug and alcohol addiction within the Fund’s broader human services priorities, and requests may support programs, operations, or capital campaigns.

The Chaney Family Foundation Grants aim to enhance the welfare of children and families while promoting public safety in Barry County, Missouri; Cabell County, West Virginia; and Jackson & Josephine Counties, Oregon. Grants up to $15,000 are available for West Virginia organizations, while those in Oregon and Missouri can apply for up to $10,000, focusing on human services, faith-based programs, and public safety initiatives.

Nonprofit and community partners in Arizona working on trauma-informed substance use prevention can apply for up to US $200,000 to support primary prevention programs. With a mission to strengthen protective factors, the Arizona Governor's Office of Youth, Faith and Family provides addiction and substance use organizations with funding to address root causes and build healthier, safer communities.

The purpose of this program is to expand access to evidence-based treatment for OUD by supporting Traveling OBOT programs that deliver MOUD and related services in community-based, nontraditional settings. Funded programs will implement low-barrier, patient-centered care models that meet individuals where they are, particularly those in underserved and high-need communities, including people experiencing homelessness, justice-involved individuals, and residents of rural areas with limited access to treatment. This initiative seeks to improve timely access to care, increase retention in treatment, and reduce opioid-related morbidity and mortality in Idaho through flexible, community- based service delivery. Programs are also expected to integrate evidence-based interventions, behavioral health services, and linkages to social supports, while advancing health equity and addressing disparities in access to OUD treatment.

The OneOhio Recovery Foundation is dedicated to addressing the opioid epidemic by allocating funds from pharmaceutical settlements to enhance substance misuse prevention, treatment, and recovery initiatives across Ohio. For Regional Grant Cycle #2, the Board authorized $40 million to support evidence-based investments in local communities. This funding model aims to create sustainable impacts while ensuring fiscal responsibility and transparency in managing resources for long-term recovery efforts.

Recovery High School Program

The goal of this state-funded continuation grant is to support the implementation of Recovery High School (RHS) Programs, as set forth in Massachusetts General Laws M.G.L. c. 71, § 91 . Operated in partnership with a public school or educational collaborative, Recovery High SchoolRHS programs offer Massachusetts students with a substance use disorder an alternative educational option in which they engage students in a process of growth and development to support their recovery while still working towards their high school diploma. These programs work with students to co-design plans and pathways that are personalized to each student’s needs and goals.

This grant supports the Department of Elementary and Secondary Education's (Department's or DESE's) Educational Vision and priorities by supporting the whole student using culturally responsive practices to meet their academic needs and support their improved and continued attendance in school while preparing them to pursue their post-secondary goals.

The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.

The Minnesota Department of Human Services, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to address the opioid overdose crisis in communities and populations that have been historically underserved and disproportionately impacted by opioid-related overdose deaths. 

The New Jersey Department of Health is launching the 'Rapid Referral for Medications for Opioid Use Disorder: Telehealth' initiative to enhance access to emergency assessments and treatment via telemedicine. This grant aims to support a telehealth provider in delivering Medication for Opioid Use Disorder (MOUD) to patients, as part of a broader strategy to combat the opioid crisis and improve substance use disorder care throughout the state.

About the Department of Health Services (DHS)

The Department of Health Services (DHS) is one of the largest state agencies in Wisconsin, with an annual budget of roughly $15 billion and more than 6,700 employees. DHS is committed to protecting and promoting the health and safety of the people of Wisconsin, making sure everyone can live their best life.

Wisconsin Alcohol Policy Project

The Division of Care and Treatment Services is seeking applications for funding to provide statewide and Wisconsin-specific alcohol prevention and policy education, training, and technical assistance. This includes providing education and information on alcohol-related trends, gaps, and opportunities and providing guidance and implementation of evidence-based and environmental strategies and policies to prevent and reduce underage drinking, alcohol misuse, and binge drinking.

Program requirements

The intention of the Wisconsin Alcohol Policy Project is to provide training, tools, and technical assistance to municipalities, law enforcement, public health, and community coalitions working to improve the alcohol environment and reduce alcohol-related problems. 

Texas Education Agency

The Texas Education Agency is the state agency that oversees primary and secondary public education. It is headed by the commissioner of education. The Texas Education Agency improves outcomes for all public school students in the state by providing leadership, guidance, and support to school systems.

The Division of Governance Interventions supports TEA’s mission and vision by providing exceptional leadership, guidance, and support to school system leadership teams and governing boards. The division collaborates with external field support agents appointed by the TEA Commissioner of Education to build sustainable systems aligned to core TEA initiatives, so that the school system thrives after the release of agency intervention. 

Instructional Materials: Tucker's Law Grant

Program Description

The Instructional Materials: Tucker’s Law Grant represents the commitment to increasing fentanyl abuse prevention and drug poisoning awareness in school systems through the creation and dissemination of evidence-based instructional materials. As established in Texas Education Code (TEC) §38.040 school systems are to annually provide to students in grades 6–12 research-based instruction on fentanyl abuse prevention and drug poisoning awareness.

The CFGFW Agile Grants program, offered by the Community Foundation of Greater Fort Wayne, provides funding up to $20,000 for innovative projects that enhance the community's quality of life. Emphasizing diversity and inclusion, these grants support various issue areas, including education, health, and arts. Applications are accepted from March to October, and organizations can apply for new initiatives or significant enhancements to existing programs. This initiative aims to create lasting, positive impacts across Allen County and Northeast Indiana.

The Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use initiative aims to enhance prevention services for infectious diseases among people who use drugs (PWUD). It encompasses two components: a biennial survey to assess service gaps and capacity, and increased support for testing and treatment services. The initiative seeks to improve data utilization in service provision, ultimately increasing testing for HBV, HCV, and HIV, and ensuring more PWUD engage in treatment and care.

The Drug-Free Communities (DFC) Support Program, initiated by the Drug-Free Communities Act of 1997, aims to bolster community coalitions dedicated to preventing youth substance use. Funded by the US HHS's Substance Abuse and Mental Health Services Administration (SAMHSA), this program focuses on collaboration among various stakeholders, including government and non-profit entities, to effectively reduce substance abuse among youth and promote protective factors within communities.

The Drug-Free Communities (DFC) Support Program aims to foster collaboration among community coalitions to combat youth substance use. Established by the Drug-Free Communities Act of 1997, it encourages partnerships among various stakeholders, including governmental and non-profit agencies. The program focuses on reducing substance use among youth and promoting protective factors within communities. This funding opportunity is available for those who have completed the initial funding cycle or experienced funding interruptions, supporting their ongoing efforts to create a healthier environment for youth.