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Search Through Addiction and Substance Abuse Grants in the U.S.
Find grants for addiction treatment, prevention, and recovery. Get funding for rehab centers, education, opioid response, and substance abuse programs
200+
Available grants
$60.1M
Total funding amount
$75K
Median grant amount
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Addiction and substance abuse grants provide critical funding for nonprofits addressing prevention, treatment, and recovery efforts. These grants support programs focused on education, mental health services, and community outreach, helping to combat the devastating effects of addiction and improve individual and public health outcomes.
Search Instrumentl's Addiction and Substance Abuse Grants Database
Find 200+ active grants with over $60.1M available for nonprofits tackling addiction challenges. Explore private, corporate, and government funding options tailored to your mission. Track deadlines, gain funder insights, and grow your impact with Instrumentl's comprehensive tools.
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Last updated: December 8, 2025. Next update: January 4, 2026.
Rolling deadline
Costco Wholesale Charitable Contributions
Costco Foundation
Youth Services
Child Welfare Services
Education
Unspecified amount
The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.
Rolling deadline
Draper Richards Kaplan Foundation Grants
Draper Richards Kaplan Foundation
Education
Social Justice / Human Rights
Energy
Up to US $300,000
The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.
Rolling deadline
Global Impact Cash Grants
Cisco Systems Foundation
Economic Services & Development
Entrepreneurship
Disaster Relief / Humanitarian Aid
Up to US $75,000
The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.
Rolling deadline
Good Neighbor Citizenship Company Grants
State Farm Companies Foundation
Disaster Preparedness
Disaster Relief / Humanitarian Aid
Firefighting & Fire Prevention
Unspecified amount
State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.
Rolling deadline
Hearst Foundation: Culture Grant
William Randolph Hearst Foundation
STEM / STEAM Education
Art Education
Artist Training & Development
More than US $100,000
The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.
Rolling deadline
Hearst Foundation: Social Service Grant
William Randolph Hearst Foundation
Sustainability
Food Access & Hunger
Family Services
More than US $100,000
The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.
Rolling deadline
Michael & Susan Dell Foundation Grants
Michael & Susan Dell Foundation
Poverty Alleviation & Services
Education - Preschool / Early Learning
Education - K through 12
More than US $50,000
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Rolling deadline
The Bank of America Foundation Sponsorship Program
Bank Of America Charitable Foundation Inc
Community Development & Revitalization
Workforce Preparation & Job Readiness
Food Access & Hunger
Unspecified amount
The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.
Rolling deadline
Tony Robbins Foundation Grant
Anthony Robbins Foundation (The Tony Robbins Foundation)
Youth Development & Leadership
Senior Services
Basic Human Needs
Unspecified amount
The Tony Robbins Foundation Grant aims to empower individuals and organizations to improve the lives of marginalized communities, including youth, seniors, and the homeless. By providing financial support to aligned nonprofits, the foundation seeks to create impactful changes globally. Eligible organizations must be 501(c)(3) nonprofits or recognized international entities, with a mission statement that resonates with the foundation's goals. The foundation does not fund personal projects or startups.
Applications due Jan 12, 2026
Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Addiction & Substance Use Disorders
Drug Use Disorder
Up to US $275,000
The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.
Applications due Feb 1, 2026
Scaife Family Foundation Grant
Scaife Family Foundation
Children’s Health & Pediatrics
Children’s Mental Health
Child Welfare Services
Unspecified amount
The Scaife Family Foundation Grant has been supporting vulnerable community members for nearly 40 years, providing over $180 million in donations to non-profits. The Foundation aims to match organizations with aligned goals, focusing on women and children, addiction prevention, and animal welfare. It offers grants for general operating and program support, prioritizing impactful programs that address societal issues. Notably, the Foundation considers proposals that foster healthy relationships and promote treatment for addiction, enhancing the welfare of both humans and animals.
Applications due Feb 23, 2026
HABRI: Addressing Evidence-Based Health Benefits of Human-Animal Interaction Grant
Human Animal Bond Research Institute
Human-Animal Interactions & Therapy
Approximately US $49,000
The Human Animal Bond Research Institute (HABRI) invites research proposals exploring the health benefits of human-animal interactions. This grant aims to fund studies that examine the positive impacts of pet ownership and animal-assisted interventions on human and animal health. Key areas of interest include mental and physical health, social isolation, and the welfare of diverse populations. Successful proposals will adhere to high standards of animal care and demonstrate actionable outcomes for policy and practice.
Applications due Mar 10, 2026
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) (357941)
US Dept. of Health & Human Services: National Institutes of Health (NIH)
Addiction & Substance Use Disorders
Drug Use Disorder
Up to US $275,000
The Cutting-Edge Basic Research Awards (CEBRA) from the National Institute on Drug Abuse (NIDA) aim to support innovative research in substance use disorders (SUDs). This program encourages high-risk, high-impact projects that may not be represented in current research portfolios. Applicants are invited to develop revolutionary techniques or test significant hypotheses that could transform addiction research. Letters of Intent are encouraged and due 30 days prior to the proposal deadline.
Applications due Mar 31, 2026
J.W. Couch Foundation Grant
Jesse W Couch Charitable Foundation
Historic Preservation
Environmental Conservation
Renewable/Sustainable Energy
More than US $50,000
The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.
Applications due May 1, 2026
US $5,000 - US $10,000
The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.
Applications due May 1, 2026
True Inspiration Awards
Chick Fil A Foundation Inc
Youth Development & Leadership
Civic Leadership Development
Healthy Habits & Behaviors
US $30,000 - US $350,000
The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.
Applications due May 11, 2026
Max and Victoria Dreyfus Foundation Grant
Max and Victoria Dreyfus Foundation
Museums & Cultural Institutions
Performing Arts
Community Culture & Heritage
US $1,000 - US $20,000
The Max and Victoria Dreyfus Foundation offers grants to support diverse initiatives, including museums, educational programs, and environmental activities. Aiming to make a significant impact with modest funding, the Foundation targets IRS-qualified non-profits in the U.S. Grants typically range from $1,000 to $20,000, fostering community development and enhancement. Organizations focused on youth, seniors, and individuals with disabilities are particularly encouraged to apply, as the Foundation seeks to empower those in need.
Applications due Aug 31, 2026
Gupta Family Foundation Grant
Gupta Family Foundation
Disaster Relief / Humanitarian Aid
Poverty Alleviation & Services
Human & Social Services
US $5,000 - US $250,000
The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.
Applications due Sep 22, 2026
Hansen Family Foundation Grant
Hansen Family Foundation
Youth Services
Animal Welfare - General
Renewable/Sustainable Energy
Unspecified amount
The Hansen Family Foundation Grant seeks to empower organizations that uphold the American values of life, liberty, and the pursuit of happiness. Focused on diverse causes like children, education, animals, environmental conservation, humanitarian efforts, and arts, the foundation is committed to supporting initiatives that create positive change. Eligible applicants must be 501(c)(3) nonprofits, while political campaigns and organizations with high budgets or overheads are ineligible. This grant fosters impactful contributions to society.
Applications due Oct 31, 2026
Dudley T. Dougherty Foundation Grant
Dudley T Dougherty Foundation Inc
Community Services
Environmental Conservation
Environment
Unspecified amount
The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.
Letter of inquiry due Oct 31, 2026
TJX Foundation Grants
The Tjx Foundation Inc
Basic Human Needs
Workforce Preparation & Job Readiness
Domestic Violence
Unspecified amount
The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.
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Grant Insights : Addiction and Substance Abuse Grants
Grant Availability
How common are grants in this category?
Common — grants in this category appear regularly across funding sources.
200+ Addiction and Substance Abuse Grants grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.
100+ Addiction and Substance Abuse Grants over $25K in average grant size
100+ Addiction and Substance Abuse Grants over $50K in average grant size
25 Addiction and Substance Abuse Grants supporting general operating expenses
200+ Addiction and Substance Abuse Grants supporting programs / projects
500+ Grants on Instrumentl focused on Addiction & Substance Use Disorders
900+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness
Grant Deadline Distribution
Over the past year, when are grant deadlines typically due for Addiction and Substance Abuse grants?
Most grants are due in the first quarter.
Q1
30.4%
Q2
29.6%
Q3
23.1%
Q4
17.0%
Typical Funding Amounts
What's the typical grant amount funded for Addiction and Substance Abuse Grants?
Grants are most commonly $75,000.
Frequently Asked Questions
What types of nonprofits can qualify for Addiction and Substance Abuse grants?
Nonprofits who want to win grants for addiction and substance abuse are usually organizations focused on prevention. They also likely provide treatment, harm reduction services, and recovery support. The funders offering these grants care about programs that serve at-risk populations. This includes low-income communities and individuals impacted by the opioid crisis. The grants you see will require your organization to have a 501(c)(3) charitable status.
Grants for addiction and substance abuse prevention typically have the highest concentration of deadlines in Q1, with 30.4% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q4.
Why are Addiction and Substance Abuse grants offered, and what do they aim to achieve?
Addiction and substance abuse grants are offered to nonprofit programs that focus on addiction prevention, harm reduction, and long-term recovery to oppose the detrimental effects of the disease on society. Over 200 grants are available, with more than $87.1 million in funding for nonprofit groups that address addiction challenges.
Funding for addiction and substance abuse grants varies widely, with award amounts ranging from a minimum of $750 to a maximum of $11,000,000. Based on Instrumentl’s data, the median grant amount for this category is $75,000, while the average grant awarded is $400,517. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Who typically funds Addiction and Substance Abuse grants?
Of the $87.1 million available, most comes from private funders. In addition, there are many federal and state/local government funders. Some of the key funders who support addiction prevention services are the US Department of Justice, followed by a lot of state-level organizations like the Kentucky Opioid Abatement Advisory Commission and other community health foundations. On the private side of grant funding, grantors include Inasmuch Foundation, Humana Foundation, and more.
What strategies can nonprofits use to improve their success rate for Addiction and Substance Abuse grants?
A carefully planned approach is needed in order to successfully win grants for substance abuse as well as addiction programs. Funders look for organizations that show a clear effect and align with the priorities of funders. These organizations also have strong community support. To greatly increase your chances of success, concentrate on all of these key areas.
- Forge completely meaningful partnerships – Collaborate closely with all healthcare providers, community organizations, and fellow nonprofits to strengthen your proposal and show a greatly united effort. Share your story using data by collecting statistics and success stories that depict the effectiveness of your programs. Some funders want to see effect that can be quantified.
- Offer an exhaustive financial plan – Show responsible financial management and present a budget detailing how each and every grant dollar will be allocated. Every funder favors organizations showing an undergoing vision. Organizations should show complete sustainability. Describe how your program will be supported once the first grant money is used up.
Visit our resource for a complete, step-by-step guide on how to find and apply for many grants. Find grants for nonprofits with a guide.
How can Instrumentl simplify the grant application process for Addiction and Substance Abuse grants?
Instrumentl simplifies the grant application process by offering standards that helps nonprofits discover relevant funding opportunities and analyze funder-giving patterns. The platform's automated alerts ensure deadlines are never missed, while detailed funder insights help organizations modify their applications to align with grantor priorities. Discover how Oasis–A Haven for Women and Children cut their time spent on grant research by 83%.