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Best Addiction and Substance Abuse Grants

Find grants for addiction treatment, prevention, and recovery. Get funding for rehab centers, education, opioid response, and substance abuse programs.

582

Available grants

$103.7M

Total funding

$33.8K

Median grant

582 grants
$103.7M total
$33.8K median

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Filters

582 Results based on applied filters

NIH Substance Use Research Grants in U.S.

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
U.S. research institutions and partners working on addiction and substance use disorders can access funding through the National Institutes of Health to test SBIRT/P approaches for alcohol, tobacco, and other drug use in adults facing health disparities. Projects must prospectively evaluate screening, brief intervention, and referral models in collaboration with healthcare and community settings.
Health Disparities & Social Determinants of Health Drug Use Disorder Alcoholism +2 more

Addiction Treatment Grants for Colorado Nonprofits via Western Colorado Community Foundation

Western Colorado Community Foundation
Private
Mesa County, Colorado
Unspecified amount
Nonprofit organizations providing addiction and substance use treatment or prevention programs in Mesa County, Colorado can apply for support from the Western Colorado Community Foundation’s Brownson Memorial Fund. Focused on substance abuse, alcoholism, and drug use disorders, this funding could help strengthen local prevention, treatment, and recovery services in the county.
Addiction & Substance Use Disorders Alcoholism Drug Use Disorder

Capacity Building Funding for Indiana Nonprofits from Community Foundation of Southern Indiana

Community Foundation of Southern Indiana
Private
Clark County, Indiana, Floyd County, Indiana
US $5,000 - US $25,000
Nonprofit 501(c)(3) organizations and fiscally sponsored projects serving Clark and Floyd counties in Indiana can seek capacity-building grants supporting governance, leadership, technology, evaluation, and strategic planning. Grants from Community Foundation of Southern Indiana, ranging from US $5,000 - US $25,000, may benefit organizations providing addiction and substance use disorder, mental health, and related community services.
Homelessness Services Education - Preschool / Early Learning Education - K through 12 +10 more

Wisconsin Community Health Funding via Green Bay Packers Foundation

Green Bay Packers Foundation
Private
Wisconsin
US $3,000 - US $8,000
Wisconsin 501(c)(3) nonprofits addressing addiction, substance use disorders, domestic violence, or broader health and wellness can seek project funding of US $3,000 - US $8,000. Grants from Green Bay Packers Foundation help eligible organizations run programs that fit the current year’s focus areas within its 2026–2029 funding cycle.
Community Services Health & Medicine Environment +7 more

Substance Use SBIRT Research Grants from NIH

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
Research institutions and other eligible organizations in the U.S. territories and states can apply for National Institutes of Health funding to test SBIRT/P approaches for alcohol, tobacco, and other drug use in adults experiencing health disparities. Projects must prospectively evaluate screening, brief intervention, and referral models in partnership with healthcare and community settings, supporting addiction and substance use disorder efforts.
Preventative Healthcare Health Disparities & Social Determinants of Health Addiction & Substance Use Disorders +3 more

Addiction Recovery Funding for Tompkins Nonprofits via United Way

United Way of Tompkins County
Private
Tompkins County, New York
Unspecified amount
Nonprofit organizations, community councils, and municipal agencies in Tompkins County addressing addiction, substance use disorders, and related mental health or basic needs may be eligible for this two-year community impact funding. Grants from United Way of Tompkins County support programs in areas like mental health, crisis intervention, and marginalized communities that strengthen local prevention, treatment, and recovery efforts.
Community Services Education Financial Literacy +29 more

Confederated Tribes Support for Addiction Programs

The Confederated Tribes of Siletz Indians
Federal Government
United States
Unspecified amount
Nonprofit and local government organizations providing education, health, public safety, or addiction-related services can seek funding for prevention, treatment, housing, arts, environmental, cultural, and other charitable programs. The Confederated Tribes of Siletz Indians provides grants to groups in eleven Oregon counties and Native American organizations across the U.S. addressing addiction and related community needs.
Native American Services Native American Culture & Heritage Addiction & Substance Use Disorders +12 more

Four County Community Foundation Support for Prevention

Four County Community Foundation
Private
Lapeer County, Michigan, Macomb County, Michigan +2 more
Unspecified amount
Nonprofit organizations, public schools, and governmental agencies in Lapeer, Macomb, Oakland, and St. Clair counties can seek funding for education, health, and community programs, including youth and adult initiatives. Four County Community Foundation supports projects such as smoking and vaping prevention, substance use education, and related health and counseling efforts that directly benefit local residents.
Academic Scholarship Programs Education Community Development & Revitalization +14 more

Addiction Recovery Funding for Maryland Nonprofits via Community Foundation

Community Foundation of the Eastern Shore
Private
Somerset County, Maryland, Wicomico County, Maryland +1 more
Unspecified amount
Nonprofits, schools, government units, and religious organizations serving Wicomico, Worcester, or Somerset Counties can seek funding for addiction, alcoholism, and drug use disorder programs, along with broader human services. Focused on community needs, Community Foundation of the Eastern Shore invites eligible organizations to submit a general Letter of Inquiry; requests submitted by the 15th receive decisions the following month.
Human & Social Services Animal Welfare - General Art & Culture +31 more

ADAMH Board Behavioral Health Grants in Franklin

ADAMH Board of Franklin County
State/Local Government
Franklin County, Ohio
Up to US $5,000
Nonprofits, faith-based organizations, and tax-exempt schools in Franklin County can apply for ADAMH Board of Franklin County’s mini-grants up to Up to US $5,000 to run community programs and events. Funding supports behavioral health awareness, prevention, stigma reduction, resilience, social connectedness, and diversity, equity, and inclusion, which may include addiction and substance use disorder initiatives.
Alcoholism Smoking Drug Use Disorder +5 more

Addiction Services Funding for Nonprofits from Atkinson Foundation

Atkinson Foundation
Private
San Mateo County, California
Up to US $20,000
Focused on community support and health services, Atkinson Foundation invites San Mateo County nonprofits to apply for grants up to Up to US $20,000. Eligible 501(c)(3) organizations under $10 million providing direct services, including alcoholism and drug use disorder treatment, mental/physical health care, and basic needs assistance, may benefit.
Immigrant Services Basic Human Needs Disability Care & Services +22 more

Grays Harbor Community Foundation Addiction Funding

Grays Harbor Community Foundation
Private
Grays Harbor County, Washington
Up to US $5,000
Organizations in Grays Harbor County addressing addiction, substance use, or related community needs can apply for Grays Harbor Community Foundation’s Quarterly Impact Grants, with awards up to US $5,000 for small, near-term projects. Programs focused on alcoholism, drug use disorder, prevention, or recovery services may benefit, with priority for funds used within two months.
Tutoring & Mentoring Educational Access & Equity Academic Success & Enrichment +33 more

Grays Harbor Community Foundation Recovery Grants

Grays Harbor Community Foundation
Private
Grays Harbor County, Washington
US $5,000 - US $30,000
Nonprofit and charitable organizations in Grays Harbor County can seek funding to start, expand, or sustain programs, equipment, or infrastructure. With a mission to improve quality of life, Grays Harbor Community Foundation provides US $5,000 - US $30,000 for efforts including substance abuse and alcoholism treatment, mental health services, crisis intervention, and related community wellness initiatives.
Supportive Housing & Shelters Equitable & Affordable Housing Homelessness Services +33 more

Colorado Addiction Program Funding via Daniels Fund

Daniels Fund
Private
Colorado, New Mexico +2 more
Approximately US $75,000
Nonprofit 501(c)(3) organizations and government equivalents providing addiction prevention, treatment, or recovery services in Colorado can access funding through the Daniels Fund, with typical awards around Approximately US $75,000. Eligible programs address drug and alcohol addiction within the Fund’s broader human services priorities, and requests may support programs, operations, or capital campaigns.
Senior Services Alcoholism Drug Use Disorder +15 more

Alcohol Education and Prevention Grants

Virginia Alcoholic Beverage Control Authority
State/Local Government
Virginia
Unspecified amount

About Virginia ABC

Virginia ABC is a leading revenue producer for the Commonwealth of Virginia and the source of future economic growth and innovation for the state. The profits that Virginia ABC contributes—collected from distilled spirits sales at ABC stores conveniently located across the state and taxes collected on beer and wine sales—provide much-needed funding for use in a multitude of state programs. This benefits all Virginians. Since its establishment in 1934, Virginia ABC has contributed $13.9 billion to the commonwealth’s general fund supporting major education, health and transportation initiatives.

Virginia ABC’s more than 4,300 employees take pride in our role as public servants and put customers first in all we do. As an authority, ABC administers alcohol-related laws with an emphasis on public safety by ensuring an orderly and regulated system for convenient sales and responsible consumption of alcohol. In 2018, Virginia ABC transitioned from a traditional state government agency to an authority, an independent political subdivision, which provides more flexibility and efficiency as a retailer, wholesaler and regulator of distilled spirits.

Alcohol Education and Prevention Grants

Virginia ABC seeks to partner, collaborate and build capacity with those who share in promoting our message of alcohol safety and responsibility. Through Education and Prevention, Virginia ABC offers annual Alcohol Education and Prevention Grants of up to $10,000.

Grantees are encouraged to build partnerships and embrace collaboration to achieve a meaningful, measurable and long-lasting impact. Members of the Community Health & Engagement team stay in contact throughout the grant cycle to provide support and encourage success.

Addiction & Substance Use Disorders Alcoholism Community / Public Safety

Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Drug Abuse is funding pilot and feasibility studies aimed at preparing for substance use and HIV prevention research trials. The program encourages innovative interventions for substance use disorders and HIV eradication, focusing on stakeholder collaboration and practical application. Projects may include assessment of service models, intervention development, and community engagement. This initiative is designed to fill critical research gaps and enhance partnerships, although applications are not currently being accepted.
Addiction & Substance Use Disorders HIV / AIDS Drug Use Disorder

RFP- Address The Opioid Overdose Crisis In Communities And Populations

Minnesota Department of Human Services Behavioral Health Administration
State/Local Government
Minnesota
US $350,000
The Minnesota Department of Human Services, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to address the opioid overdose crisis in communities and populations that have been historically underserved and disproportionately impacted by opioid-related overdose deaths. 
Addiction & Substance Use Disorders Drug Use Disorder

Traveling Office-Based Opioid Treatment (OBOT) Funding Opportunity

Idaho Department of Health and Welfare
State/Local Government
Idaho
Unspecified amount

The purpose of this program is to expand access to evidence-based treatment for OUD by supporting Traveling OBOT programs that deliver MOUD and related services in community-based, nontraditional settings. Funded programs will implement low-barrier, patient-centered care models that meet individuals where they are, particularly those in underserved and high-need communities, including people experiencing homelessness, justice-involved individuals, and residents of rural areas with limited access to treatment. This initiative seeks to improve timely access to care, increase retention in treatment, and reduce opioid-related morbidity and mortality in Idaho through flexible, community- based service delivery. Programs are also expected to integrate evidence-based interventions, behavioral health services, and linkages to social supports, while advancing health equity and addressing disparities in access to OUD treatment.

Addiction & Substance Use Disorders Drug Use Disorder

SSUS State Opioid NOFA

State of New Jersey Department of Health
State/Local Government
New Jersey
Unspecified amount
SSUS State Opioid Grant shall be used to fund direct services for Core Harm Reduction, Harm Reduction Health, Overdose Prevention & Response Innovation, and planning activities for Capital Improvements to clients with behaviors that make them vulnerable to HIV/STD transmission as a result of injection drug use and support harm reduction and overdose prevention services at syringe access locations, harm reduction centers and county health departments.  This opportunity is limited to entities who were funded under DHSTS Opioid 2026 & DHSTS Opioid Expansion 2026. 
HIV / AIDS Addiction & Substance Use Disorders Drug Use Disorder

Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $2,500,000
This funding opportunity invites Small Business Technology Transfer (STTR) grant applications aimed at developing FDA-regulated medical products for patients with opioid and stimulant use disorders. Projects may focus on pharmacotherapeutics or diagnostic devices, including software. The initiative seeks to address the ongoing opioid crisis by supporting innovations that enhance treatment options for individuals and communities affected by these disorders.
Drug Use Disorder Addiction & Substance Use Disorders Pharmacology +1 more

HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $140,000
The HEAL Initiative's Career Development Awards aim to empower early career researchers and clinicians in implementation science. By providing training and funding, this initiative seeks to address substance use prevention and treatment through research projects that align with the HHS Overdose Prevention Strategy. Focused on vital areas such as opioid prescribing, OUD treatment, and recovery support, the program aspires to cultivate a new generation of experts who will significantly impact addiction clinical practices and mentorship.
Drug Use Disorder Addiction & Substance Use Disorders

Emergency Department Peer Navigator Program

State of New Jersey Department of Health
State/Local Government
New Jersey
Up to US $250,000
The Emergency Department Peer Navigator Program, funded by the New Jersey Department of Health, aims to tackle opioid-related challenges by embedding peer navigators in emergency departments in Newark, NJ. These navigators, who have lived experience with substance use, facilitate access to care and resources, thereby reducing overdose risks and unnecessary emergency department visits. This initiative is part of a broader strategy to enhance addiction recovery services across the state.
Addiction & Substance Use Disorders Drug Use Disorder Health Care Access & Delivery

Local Public Health Overdose Fatality Review Teams 2027 RFA

State of New Jersey Department of Health
State/Local Government
Atlantic County, New Jersey, Bergen County, New Jersey +17 more
Up to US $1,500,000
The Local Public Health Overdose Fatality Review Teams Grant Program, administered by the New Jersey Department of Health, aims to enhance public health responses to overdose fatalities. This initiative will provide $75,000 to 20 local health departments to support their established review teams. These teams will analyze overdose cases, identify systemic gaps, and devise strategies to mitigate future overdoses, ultimately working towards reducing overdose-related deaths in their communities.
Addiction & Substance Use Disorders Drug Use Disorder

AL Opioid Settlement Fund

Alabama Department of Mental Health (ADMH)
State/Local Government
Alabama
Unspecified amount

Oversight Commission on Alabama Opioid Settlement Fund Grant Program

At the recommendation of the Oversight Commission on Alabama Opioid Settlement Funds, the Legislature has appropriated opioid settlement dollars for ADMH to administer prevention, treatment, and recovery grants. The purpose of this grant program is to prevent, reduce, treat, or mitigate the effects of opioid substance use. To date, the Legislature has appropriated three rounds of grants.

Addiction & Substance Use Disorders Drug Use Disorder

Rapid Referral for Medications for Opioid Use Disorder Telehealth

State of New Jersey Department of Health
State/Local Government
New Jersey
Up to US $1,000,000
The New Jersey Department of Health is launching the 'Rapid Referral for Medications for Opioid Use Disorder: Telehealth' initiative to enhance access to emergency assessments and treatment via telemedicine. This grant aims to support a telehealth provider in delivering Medication for Opioid Use Disorder (MOUD) to patients, as part of a broader strategy to combat the opioid crisis and improve substance use disorder care throughout the state.
Addiction & Substance Use Disorders Drug Use Disorder Telemedicine & Telehealth

Walker Foundation Support for Minnesota Equity

Archie D & Bertha H Walker Foundation
Private
Minnesota
Up to US $5,000
Nonprofit 501(c)(3) organizations in Minnesota’s Twin Cities metro working on addiction, substance use disorders, or related racial justice issues can apply for the Archie D & Bertha H Walker Foundation’s annual grants, offering up to US $5,000. Eligible applicants must be primary 501(c)(3) holders registered in Minnesota and located in Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, or Washington counties.
Racial / Ethnic Justice & Rights Art & Culture Alcoholism +7 more

NIH Addiction Research Education Grants in U.S.

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
Organizations providing research education experiences in addiction and substance use disorders in the U.S. and territories can apply for NIH R25 funding, with awards up to US $1,250,000. Grants from the National Institutes of Health help expand skills-development courses and hands-on research experiences to build a more diverse substance use and addiction scientific workforce.
Addiction & Substance Use Disorders STEM / STEAM Education Biology +3 more

Addiction and Substance Abuse Grants Highlights

Addiction and substance abuse grants provide critical funding for nonprofits addressing prevention, treatment, and recovery efforts. These grants support programs focused on education, mental health services, and community outreach, helping to combat the devastating effects of addiction and improve individual and public health outcomes.


Search Instrumentl's Addiction and Substance Abuse Grants Database


Find 230 active grants with over $60.8M available for nonprofits tackling addiction challenges. Explore private, corporate, and government funding options tailored to your mission. Track deadlines, gain funder insights, and grow your impact with Instrumentl's comprehensive tools.

Grant Insights : Addiction and Substance Abuse Grants

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Addiction and Substance Abuse Grants grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Addiction and Substance Abuse Grants over $25K in average grant size

98 Addiction and Substance Abuse Grants over $50K in average grant size

28 Addiction and Substance Abuse Grants supporting general operating expenses

200+ Addiction and Substance Abuse Grants supporting programs / projects

500+ Grants on Instrumentl focused on Addiction & Substance Use Disorders

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Addiction and Substance Abuse grants?

Most grants are due in the first quarter.

Q1
30.6%
Q2
28.8%
Q3
22.3%
Q4
18.2%

Typical Funding Amounts

What's the typical grant amount funded for Addiction and Substance Abuse Grants?

Grants are most commonly $100,000.

$500 $500 Min.
$100,000 $100 K Median
$413,421 $413.4 K Average
$11,000,000 $11 M Max.

Frequently asked questions

Nonprofits who want to win grants for addiction and substance abuse are usually organizations focused on prevention. They also likely provide treatment, harm reduction services, and recovery support. The funders offering these grants care about programs that serve at-risk populations. This includes low-income communities and individuals impacted by the opioid crisis. The grants you see will require your organization to have a 501(c)(3) charitable status.

Grants for addiction and substance abuse prevention typically have the highest concentration of deadlines in Q1, with 30.6% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q4.

Addiction and substance abuse grants are offered to nonprofit programs that focus on addiction prevention, harm reduction, and long-term recovery to oppose the detrimental effects of the disease on society. Over 200 grants are available, with more than $87.1 million in funding for nonprofit groups that address addiction challenges.

Funding for addiction and substance abuse grants varies widely, with award amounts ranging from a minimum of $500 to a maximum of $11,000,000. Based on Instrumentl’s data, the median grant amount for this category is $100,000, while the average grant awarded is $413,421. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Of the $87.1 million available, most comes from private funders. In addition, there are many federal and state/local government funders. Some of the key funders who support addiction prevention services are the US Department of Justice, followed by a lot of state-level organizations like the Kentucky Opioid Abatement Advisory Commission and other community health foundations. On the private side of grant funding, grantors include Inasmuch Foundation, Humana Foundation, and more.

A carefully planned approach is needed in order to successfully win grants for substance abuse as well as addiction programs. Funders look for organizations that show a clear effect and align with the priorities of funders. These organizations also have strong community support. To greatly increase your chances of success, concentrate on all of these key areas.

  • Forge completely meaningful partnerships – Collaborate closely with all healthcare providers, community organizations, and fellow nonprofits to strengthen your proposal and show a greatly united effort.
  • Share your story using data by collecting statistics and success stories that depict the effectiveness of your programs. Some funders want to see effect that can be quantified.
  • Offer an exhaustive financial plan – Show responsible financial management and present a budget detailing how each and every grant dollar will be allocated.
  • Every funder favors organizations showing an undergoing vision. Organizations should show complete sustainability. Describe how your program will be supported once the first grant money is used up.

Visit our resource for a complete, step-by-step guide on how to find and apply for many grants. Find grants for nonprofits with a guide.

Instrumentl simplifies the grant application process by offering standards that helps nonprofits discover relevant funding opportunities and analyze funder-giving patterns. The platform's automated alerts ensure deadlines are never missed, while detailed funder insights help organizations modify their applications to align with grantor priorities. Discover how Oasis–A Haven for Women and Children cut their time spent on grant research by 83%.

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