Upcoming Webinar
Steal These 5 AI Grant Workflows, From Prospecting to Spend-Down.
Thu, Sep 17 @ 2PM ET
Why Instrumentl
Full Cycle Grant Platform
By Customer
Featured
$1.1m More Per Year
The Instrumentl Impact Report
Explore
Learn
Connect
Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability
32,000+
Available grants
$8.26B
Total funding
$6K
Median grant
Skip the search. Get matched with grants that fit your non-profit.
Smart recommendations based on your profile — in minutes.
Funding Innovative Research
Cannonball Kids’ cancer Foundation (CKc) prioritizes funding clinical trials, research that is nearing translation to a clinical trial, and young investigator grants.
Grants funded by CKc must be innovative and provide better quality of life or symptom relief than current treatments.
When possible, CKc will prioritize funding research:
When possible, CKc will prioritize funding researchers of diverse backgrounds.
For CKc, “innovation” means the invention or application of novel methods or treatments, specifically treatments that have fewer side-effects than standard care, increase a child’s quality of life, and/or create an option for care where there otherwise were few or none (either on primary diagnosis, relapse, or for recalcitrant cancers).
Research Grants
Grant Program: Clinical Trial
$200,000 over 3 years
Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations.
Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.
Cape Fear River Assembly Scholarship
Any high school or college student accepted/enrolled in a college in the Cape Fear River Basin.
Affordable Housing and Sustainable Communities (AHSC) Program Round 10
The AHSC Program funds projects that implement land-use, housing, transportation, and agricultural land preservation practices that reduce greenhouse gas (GHG) emissions.
The AHSC Program provides grants and/or loans for Projects that achieve GHG Reductions and benefit communities across California, particularly DACs, Low-Income Communities, and Low-Income Households, through increasing accessibility of affordable housing, employment centers, and Key Destinations via low-carbon transportation. These investments result in fewer vehicle miles traveled (VMT) through shortened or reduced vehicle trip length or mode shift to transit, bicycling, or walking.
The purpose of these Program Guidelines is to implement Division 44, Part 1 Chapter 2 of the California Public Resources Code (PRC) (commencing with Section 75200), which establishes the Affordable Housing and Sustainable Communities (AHSC) Program, hereinafter referred to as the AHSC Program. Per the California Public Resources Code, the purpose of the AHSC Program is to reduce greenhouse gas (GHG) emissions through Projects that implement land use, housing, transportation, and Agricultural Land preservation practices to support infill and compact development, and that support related and coordinated public policy objectives, including the following:
Texas Health and Human Services
Texas Health and Human Services, also known as the Texas Health and Human Services Commission (HHSC), helps more than 7.5 million Texans every month. The agency supports the needs of mothers, children and families through programs such as Medicaid, CHIP, SNAP, women’s health and behavioral health services.
HHSC provides long-term services and supports for seniors and people with disabilities, and operates state supported living centers for residents with intellectual and developmental disabilities and state psychiatric hospitals. HHSC also regulates health care providers, professions and facilities to protect the health and safety of Texans.
Pediatric Tele-Connectivity Resource Program for Rural Texas
Executive Summary
The Texas Health and Human Services Commission (HHSC), the System Agency, is accepting applications for the State Fiscal Year 2026 Pediatric Tele-Connectivity Resource Program for Rural Texas Grant Program. The purpose of this program is to connect Rural Hospitals (RHs) and Rural Health Clinics (RHCs) with (i) pediatric specialists and pediatric subspecialists who provide Telemedicine Medical Services (TMS) or (ii) an institution of higher education that is a member of the Texas Child Mental Health Care Consortium established under Chapter 113 of the Texas Health and Safety Code. Applicants should reference Section II, Scope of Grant Project, for further detailed information regarding the purpose, background, eligible activities, and program requirements.
There have been a lot of improvements in our Tennessee communities since the former Federal Transportation Enhancement (TE) Program, now known as the Transportation Alternatives Program (TAP), began providing funds to local governments in 1991. Nearly $409 million in grants have been distributed by the Department. The money has gone to hundreds of communities across the Volunteer State to build sidewalks and bike lanes, update ADA accessibility and to renovate historic transportation facilities and other transportation-related structures. The impact of some of the projects is primarily local, whereas projects such as the wildflower planting along roadways across the state can be enjoyed annually by thousands of Tennesseans and tourists. Whether large or small, the projects serve the same purposes - improving access and providing a better quality of life for people in the state of Tennessee.
In order to be considered for project funding, the application must fall into one or more of the following specific categories as defined by federal legislation and relate to surface transportation
About the Indiana Department of Veterans Affairs
The Indiana Department of Veterans Affairs (IDVA) is a state agency dedicated to serving. Its mission is to Support, Serve, and Advocate for the Indiana Veterans Community. IDVA aims to make Indiana the choice for veterans to Live, Work, and Thrive.
Grants for Veterans’ Services (GVS)
The Indiana Department of Veterans Affairs is seeking applications for the Grants for Veterans’ Services program. This solicitation is open to non-profit organizations registered with the Indiana Secretary of State.
The grant amounts will be between $10,000 and $75,000, depending on each applicant’s need for funds, the availability of funding, and the volume of eligible applicants.
All applications, procedures, and documentation should follow the Indiana Code, Indiana Administrative Code, and Indiana Department of Veterans Affairs’ policies.
Grants for Veterans’ Services may be utilized to provide the following services to caregivers and family members:
State and Tribal Wildlife Grants
The State and Tribal Wildlife Grants Program provides federal funding to the states for conservation of nongame species and their habitat. The goal of the program is to prevent these species from being listed as threatened or endangered under the Endangered Species Act. This important program supports conservation of species that are not hunted or fished, many of which had no previous source of conservation funding. In addition, the program’s focus on proactive conservation measures designed to halt or prevent population declines is key, as conservation is often more effective and efficient before species undergo declines sufficient to warrant Endangered Species Act action.
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.50B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.3% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $35,000, while the average grant awarded is $672,603. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.