Best Addiction and Substance Abuse Grants

The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.

Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.

The Scott Hudgens Family Foundation Grant, established in memory of World War II veteran Scott Hudgens, supports public charities addressing the needs of Gwinnett County, Georgia, and the metropolitan Atlanta area. The foundation focuses on improving the lives of those facing socio-economic disadvantages, promoting self-sufficiency through educational initiatives, and considering capital contributions for long-term impact. Grants are limited to qualified public charities, with a review of one proposal per year per organization.

The Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) aims to enhance research in Anesthesia, Addiction Medicine, and Pain Medicine. It focuses on critical areas such as clinical trial endpoints for chronic pain, outcome measures in stimulant use disorders, and neurodevelopmental assessments in pediatric patients. The initiative encourages applicants to propose comprehensive, evidence-based plans to improve the prescribing of analgesic and anesthetic drug products, with multiple awards available.

Indigo Hope Foundation: Addiction Recovery Programs Grant

Funding programs that offer treatment, counseling, recovery support services, and harm reduction for individuals battling addiction.

Key Focus Areas:

• Treatment Services
• Recovery Support
• Harm Reduction
• Family Programs

Example Programs We Fund:

• Outpatient counseling programs
• Peer recovery support
• Addiction Recovery Residential Programs
• Family therapy services

Organizations providing research education experiences in addiction and substance use disorders in the U.S. and territories can apply for NIH R25 funding, with awards up to US $1,250,000. Grants from the National Institutes of Health help expand skills-development courses and hands-on research experiences to build a more diverse substance use and addiction scientific workforce.

The McKeesport Community Fund, established in 2017 by Trulieve under the Pittsburgh Foundation, aims to enhance community welfare by supporting local 501(c)(3) nonprofits. It focuses on education, job training, youth initiatives, and economic development, providing around $50,000 annually for projects that benefit McKeesport residents. Eligible organizations can apply for grants between $1,000 to $50,000, depending on the project scope, ensuring vital resources for community revitalization.

Nonprofit and community partners in Arizona working on trauma-informed substance use prevention can apply for up to US $200,000 to support primary prevention programs. With a mission to strengthen protective factors, the Arizona Governor's Office of Youth, Faith and Family provides addiction and substance use organizations with funding to address root causes and build healthier, safer communities.

The Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional) invites applications that address urgent research needs in substance use epidemiology and health services. This funding opportunity encourages pilot studies focusing on emerging drug issues, unexpected prescription drug abuse trends, and timely medical system challenges. Letters of Intent are recommended 30 days before the proposal deadline, emphasizing the necessity for rapid review and funding to address pressing scientific questions.

The City of Naperville is allocating $100,000 from the National Multistate Opioid Settlement for grants aimed at opioid remediation programs. Eligible organizations include school districts, medical providers, and faith communities, among others. Approved programs focus on distributing Naloxone, providing medication-assisted treatment, and expanding recovery services, particularly for vulnerable populations. This initiative aims to significantly impact the community by enhancing education and resources to combat opioid misuse.

The Reliant Foundation Community Grants support charitable initiatives from 501(c)3 non-profits in Central and MetroWest Massachusetts. Priority is given to programs addressing substance use disorders and mental health services for youth. Collaborations aligned with Community Health Improvement Plans are encouraged. Grants are not available for individuals, for-profit businesses, or funding specific salaries. This initiative aims to enhance the health and wellbeing of all community members.

Nonprofit 501(c)(3) organizations in Minnesota’s Twin Cities metro working on addiction, substance use disorders, or related racial justice issues can apply for the Archie D & Bertha H Walker Foundation’s annual grants, offering up to US $5,000. Eligible applicants must be primary 501(c)(3) holders registered in Minnesota and located in Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, or Washington counties.

What is Granite United Way?

Granite United Way is a nonprofit organization that makes strategic investments in our community to help people learn, earn, and be healthy. Our impact covers more than 85% of New Hampshire and Windsor County, Vermont. With the support of more than 22,000 donors and volunteers, we are working together to provide more than $14 million in support to over 400,000 individuals.

If you are concerned about issues in our community like homelessness, education gaps, and health disparities, you're not alone. Many of us want to make a meaningful difference, but aren't sure where to start.

At Granite United Way, we streamline that process by connecting your support to the most pressing issues in our community. We remove barriers and create opportunities for people to make a positive impact in our community. When you partner with us, you help meet critical needs and create a ripple effect of positive change throughout our community.

Opioid Abatement Community Grants Program (OACGP): Short-Term Responsive Grants

ranite United Way (GUW) administers the Opioid Abatement Community Grants Program (OACGP) on behalf of the New Hampshire Department of Health and Human Services and the Opioid Abatement Advisory Commission. Through this program, $10 million in settlement funds will be invested over two years to support community-based efforts that prevent, reduce, and address the harms of the opioid crisis across New Hampshire. OACGP supports programs, partnerships, and community-led work that strengthen prevention, treatment, recovery, and long-term wellbeing. Funding is available to nonprofit organizations, municipalities, school districts, and other eligible entities serving New Hampshire communities.

Grant Opportunities

• Short-Term Responsive Grants:
  • Up to $15,000 for timely projects that address emerging needs, fill gaps, or strengthen community capacity.

Granite United Way administers the Opioid Abatement Community Grants Program (OACGP) to combat the opioid crisis in New Hampshire. This initiative allocates $10 million over two years to support community-based prevention, treatment, and recovery efforts. Eligible applicants include nonprofits, municipalities, and governmental entities dedicated to improving community well-being. The program aims to create lasting positive change by addressing critical health and social issues related to opioid abuse.

About Us

The Foundation for a Healthy Kentucky (FHKY) is a nonprofit organization funded by an endowment that aims to transform our state so that every Kentuckian has what they need to live a healthy life. Since it opened its doors in 2001, the Foundation has invested millions in health policy advocacy, research, and demonstration projects across the Commonwealth.

Partnerships for Success Grants

Partnerships for Success (PFS) provides funding to enhance and support Kentucky community-based organizations that serve communities with limited opportunities. Applicants should focus on reducing alcohol, nicotine (including vaping), and cannabis use/misuse and related consequences by implementing evidence-based prevention programs, practices, and policies that are trauma and resilience informed, and responsive to local and community context. The Foundation for a Healthy Kentucky (FHKY) is facilitating this funding opportunity as one of its pass-through grant programs. The project is supported by the Kentucky PFS 2023 Grant via the Substance Abuse and Mental Health Services Administration (SAMHSA) Grant H79SP083680.

Grants will provide up to $50,000 in funding for 12 months. 

Goal

To provide funding that enhances and supports evidence-based strategies to prevent alcohol, nicotine (including vaping), and cannabis use/misuse in communities that are at higher risk in Kentucky.

Overview

This funding opportunity allows potential grantees to creatively address localized behavioral health-related issues. Funding is intended to support solutions that address the issues, identified by those who live and work locally, as most relevant to communities that are at higher risk in Kentucky.

Proposed projects should:

• Focus on communities with limited opportunities as the primary focus of a proposed or existing project or program, including leadership and decision-making power.
• Make communities that are at higher risk the primary beneficiaries of the project or program's outcomes.
• Address a substance use challenge identified by the community.
• Plan, develop, implement, and/or sustain a prevention initiative.

The OneOhio Recovery Foundation is dedicated to addressing the opioid epidemic by allocating funds from pharmaceutical settlements to enhance substance misuse prevention, treatment, and recovery initiatives across Ohio. For Regional Grant Cycle #2, the Board authorized $40 million to support evidence-based investments in local communities. This funding model aims to create sustainable impacts while ensuring fiscal responsibility and transparency in managing resources for long-term recovery efforts.

The Virginia ABC Grants provide funding of up to $10,000 for organizations aiming to prevent underage and high-risk drinking. Through community collaboration and education, these grants support various entities including schools and nonprofits. The program focuses on building capacity for effective alcohol education and emphasizes prevention efforts. Eligible applicants must align with the mission to promote alcohol safety and responsibility, ensuring a significant impact on community health and well-being.

Johnson County Community Development Office

The mission of the Johnson County Community Development Office is to secure federal, state and local funding for community development activities, to provide leadership in coordinating these activities, and to ensure continued funding through accountable, efficient and effective use of these funds in serving low- to moderate-income residents in Johnson County.

Community Development Block Grant

The Community Development Block Grant (CDBG) program provides annual grants on a formula basis to states, cities, and counties to develop viable urban communities by providing decent housing and a suitable living environment, and by expanding economic opportunities, principally for low- and moderate-income persons. The program is authorized under Title 1 of the Housing and Community Development Act of 1974.

Federal Objective

The primary objective of Title I of the Housing and Community Development Act of 1974, as amended, is to promote “development of viable urban communities, by providing decent housing and a suitable living environment and expanding economic opportunities, principally for persons of low and moderate income.” The Code of Federal Regulations, 24 CFR 570 Subparts A through O, govern how this objective is to be carried out.

Johnson County’s Priority Objectives

The primary goal of the program is to provide federal financial assistance to eligible applicants for the purpose of community development. In pursuit of this goal, the County has identified several strategies in the Plan that applicants should consider when applying. A unit of local government may also use local goals and/or objectives in support of a specific activity for which funds are requested. As stated in the 2025-2029 Consolidated Plan, the priority needs are: Non-Housing Community Development; Affordable Housing; and Homelessness.

The CDBG program includes funding for: 1) Housing Projects; 2) Public Facilities Projects 3) Public Services Projects; and 4) Economic Development Projects

Public Services Projects

Eligible Activities

Once the National Objective is determined then the activity must be a public service as defined at 24 CFR 570.201(e). Provision of public services, including but not limited to those concerned with employment, crime prevention, childcare, health, drug abuse, education, fair housing counseling, energy conservation, welfare, homebuyer downpayment assistance or recreational needs.

About the Department of Health Services (DHS)

The Department of Health Services (DHS) is one of the largest state agencies in Wisconsin, with an annual budget of roughly $15 billion and more than 6,700 employees. DHS is committed to protecting and promoting the health and safety of the people of Wisconsin, making sure everyone can live their best life.

Wisconsin Alcohol Policy Project

The Division of Care and Treatment Services is seeking applications for funding to provide statewide and Wisconsin-specific alcohol prevention and policy education, training, and technical assistance. This includes providing education and information on alcohol-related trends, gaps, and opportunities and providing guidance and implementation of evidence-based and environmental strategies and policies to prevent and reduce underage drinking, alcohol misuse, and binge drinking.

Program requirements

The intention of the Wisconsin Alcohol Policy Project is to provide training, tools, and technical assistance to municipalities, law enforcement, public health, and community coalitions working to improve the alcohol environment and reduce alcohol-related problems. 

The Southwest Iowa Mental Health and Substance Abuse Fund Grant, managed by the Community Foundation for Western Iowa, aims to enhance nonprofit service providers' capacity to address mental health and substance abuse issues. By focusing on education, awareness, and training, the fund seeks to create sustainable positive impacts in communities across nine Iowa counties. This initiative responds to pressing community needs and works to reduce stigma while improving access to essential services.

Federally recognized Tribal nations and Wisconsin county agencies in Wisconsin can receive funding to cover room and board for Medicaid members in residential substance use disorder treatment programs. The Wisconsin Department of Health Services supports treatment for people with opioid use disorder or at risk of overdose, helping expand access to addiction and substance abuse services.

The Healthcare Foundation of Wilson (HFW) offers responsive grants aimed at improving health and wellness in the Wilson, NC community. Established in 2014, HFW prioritizes tax-exempt organizations that address healthcare access, active living, and mental health. Funding is directed towards innovative programs, especially those targeting youth, while ensuring eligibility criteria, including three years of operational history, are met. This initiative reflects HFW's commitment to reinvesting resources back into the community.

MN Community Justice Reinvestment Grant Program

In 2016, the Minnesota legislature established the Community Justice Reinvestment Account to provide supportive services to justice-impacted individuals to reduce further involvement in the criminal justice system. This Account is used to create the Community Justice Reinvestment Grant program, which most recently distributed $1,017,474.54 in 2024 to fund:

• Chemical dependency and mental health treatment programs,
• Programs that improve supervision,
• Pretrial and precharge supervision programs,
• Programs to reduce recidivism of controlled substances offenders on probation or supervised release or participating in drug courts,
• Support local participation in drug court initiatives approved by the Judicial Council.

Nonprofits, healthcare providers, academic institutions, businesses, and governmental or tribal organizations in Douglas County can seek emergency funding for opioid and substance use disorder services, including prevention, treatment, recovery, and harm reduction. Douglas County Community Foundation supports organizations facing financial hardship with US $20,000 - US $100,000 to sustain critical addiction and substance abuse programs.

The M&M Area Community Foundation (MMACF) provides essential financial support to enhance community initiatives in Marinette and Menominee Counties. With multiple grant cycles throughout the year, they cater to diverse needs of local nonprofits, schools, and organizations. MMACF emphasizes philanthropy and collaboration, aiming to foster positive change and tackle local challenges. Their funds include the Youth Field of Interest Fund, Alcohol & Drug Abuse Prevention Fund, and more, ensuring impactful investments in community development.

The Indiana Court Alcohol & Drug Grant Program, administered by the Indiana Office of Court Services, aims to enhance the effectiveness of Court-Administered Alcohol and Drug Programs throughout Indiana. With grants up to $2,500, this initiative focuses on activities such as curriculum development and technology upgrades. Applicants must contribute at least 20% of the project cost. This program reflects the Indiana Judicial Branch's commitment to improving justice and public safety through innovative and accessible solutions.

The Chaney Family Foundation Grants aim to enhance the welfare of children and families while promoting public safety in Barry County, Missouri; Cabell County, West Virginia; and Jackson & Josephine Counties, Oregon. Grants up to $15,000 are available for West Virginia organizations, while those in Oregon and Missouri can apply for up to $10,000, focusing on human services, faith-based programs, and public safety initiatives.