Best Addiction and Substance Abuse Grants

The HEAL Initiative offers Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01), targeting early career researchers and clinicians. This program emphasizes training in implementation science methods to tackle opioid use disorder and enhance recovery support services. By fostering expertise in these areas, the initiative aims to combat the overdose crisis and cultivate future leaders in addiction research and clinical practice.

Organizations providing research education experiences in addiction and substance use disorders in the U.S. and territories can apply for NIH R25 funding, with awards up to US $1,250,000. Grants from the National Institutes of Health help expand skills-development courses and hands-on research experiences to build a more diverse substance use and addiction scientific workforce.

Nonprofit 501(c)(3) organizations in Minnesota’s Twin Cities metro working on addiction, substance use disorders, or related racial justice issues can apply for the Archie D & Bertha H Walker Foundation’s annual grants, offering up to US $5,000. Eligible applicants must be primary 501(c)(3) holders registered in Minnesota and located in Anoka, Carver, Dakota, Hennepin, Ramsey, Scott, or Washington counties.

CAREs Flexible Funding

Healthcare Foundation of Wilson (HFW) CAREs about our nonprofit partners that provide CARE (Compassion, Assistance, Responsiveness, and Engagement) for our community. As a response to support the work done by these organizations, the HFW seeks proposals from nonprofit organizations located in Wilson, NC, for an unrestricted funds grant. Funds may be used for general operating support.

Request Range:

• Up to $15,000

As a partner organization, it is essential to note that maintaining compliance with the public support test is the nonprofit’s own responsibility. Please review the information provided on the IRS website. If you are unsure of your public support status, please contact an accounting professional. 

Purpose:

Nonprofits can utilize these funds to support any operating needs within the organization. These funds are not intended for past, present, or future programming needs.

Award Distribution:

Awards will be issued quarterly through a competitive grant process. Up to $50,000 will be issued each quarter.

The nonprofit’s mission and/or vision must align with at least one of our four focus areas.

• Access to Healthcare
• Active Living / Healthy Eating
• Alcohol / Substance Misuse
• Behavioral / Mental Health

HFW Strategic Grants

Healthcare Foundation of Wilson seeks ideas from organizations located in Wilson, NC with a desire to provide programming and services related to our focus areas.

• Access to Healthcare
• Active Living / Healthy Eating
• Alcohol / Substance Misuse
• Behavioral / Mental Health

Request Range

• The amount of the grant can vary but needs to support the development of the program.
• The board of directors prefer to be a partner in a project and not the funder of the entire project.

Funding Priorities

The foundation prioritizes:

• Innovative ideas that support the development or expansion of one or more of our four focus areas.
• Programs focused on youth through age 29.
• Eligible organizations who implement or have a desire to start evidence-based program models identified as having significant outcomes in one or more of the four focus areas.

New Jersey Department of Health

The scope of work for the public health system is ever-expanding, and the Department is on the frontlines in leading the response to public health challenges. The Department has three primary branches – Public Health Services, Health Systems, and Integrated Health. All work collaboratively toward improving health by strengthening New Jersey’s health system.

Our Mission: Protect the public’s health, promote healthy communities, and continue to improve the quality of health care in New Jersey.

Rural Health Transformation Program: Improving Chronic Disease Outcomes in Rural New Jersey

The Division of Health Promotion, through its Community Health and Wellness Unit (CHWU), announces the availability of funding awarded to the State under the Rural Health Transformation (RHT) Grant Program. This funding opportunity is designed to support innovative and sustainable strategies that improve chronic disease outcomes, increase access to quality healthcare services, address health disparities, and strengthen healthcare systems in rural communities.

The grant seeks to advance community-driven solutions that promote health equity, improve health outcomes, and enhance care coordination across rural health systems.

Purpose and Goals

The purpose of the Rural Health Transformation Grant is to support projects that transform rural healthcare delivery by addressing systemic challenges and community-identified needs. Grant goals include, but are not limited to:

• Improving access to healthcare services in rural and underserved areas
• Strengthening rural healthcare infrastructure and workforce capacity
• Enhancing care coordination and integration of services
• Addressing SDOH impacting rural populations
• Promoting preventive care, wellness, and chronic disease management

Proposed Grant Activities

• Activity 5.2a: NJ Rural Southern Physical Activity and Nutrition Program (NJ R-SPAN)
• Activity 5.2b: Umbrella Hub Organization
• Activity 5.3b: Enhancing Rural Cancer-Focused Healthcare (ERCH)
• Activity 5.3c: Rural Pharmacy Medication Management Therapy Program
• Activity 5.3d: Rural Health Screening and Education
• Activity 5.4b: Safe Communities: Youth Violence Prevention in Rural Communities

Activity 5.3c: Rural Pharmacy Medication Management Therapy Program

The purpose of Activity 5.3c- Rural Pharmacy Medication Management Therapy Program is to improve health outcomes in rural communities through Medication Therapy Management (MTM), tobacco cessation services, and chronic disease prevention and management that are not covered by medical insurance. This program aims to address medication adherence/polypharmacy and tobacco use for people with or at risk for chronic conditions, delay disease progression, and support overall well-being, with a particular focus on uninsured and underinsured populations. Programs should address chronic conditions such as diabetes, hypertension, heart disease, and hyperlipidemia, in addition to addressing related risk factors such as tobacco product use. Funding is intended to support community-based approaches that increase access to disease management tools and services, strengthen patient engagement, and foster healthier communities.

This funding opportunity encourages Small Business Technology Transfer (STTR) grant applications focused on developing FDA-regulated medical products for patients with opioid and stimulant use disorders (OUD/StUD). The grant supports projects in pharmacotherapeutics and medical devices, including software as a medical device. It aims to address the national crisis by fostering innovative solutions that meet the needs of affected individuals and communities. Companies with promising technologies are invited to apply.

The Cooperative Agreement to Support Activities Related to Analgesics, Anesthetics, and Addiction (U01) aims to enhance research in Anesthesia, Addiction Medicine, and Pain Medicine. It focuses on critical areas such as clinical trial endpoints for chronic pain, outcome measures in stimulant use disorders, and neurodevelopmental assessments in pediatric patients. The initiative encourages applicants to propose comprehensive, evidence-based plans to improve the prescribing of analgesic and anesthetic drug products, with multiple awards available.

The Indiana Court Alcohol & Drug Grant Program, administered by the Indiana Office of Court Services, aims to enhance the effectiveness of Court-Administered Alcohol and Drug Programs throughout Indiana. With grants up to $2,500, this initiative focuses on activities such as curriculum development and technology upgrades. Applicants must contribute at least 20% of the project cost. This program reflects the Indiana Judicial Branch's commitment to improving justice and public safety through innovative and accessible solutions.

MN Community Justice Reinvestment Grant Program

In 2016, the Minnesota legislature established the Community Justice Reinvestment Account to provide supportive services to justice-impacted individuals to reduce further involvement in the criminal justice system. This Account is used to create the Community Justice Reinvestment Grant program, which most recently distributed $1,017,474.54 in 2024 to fund:

• Chemical dependency and mental health treatment programs,
• Programs that improve supervision,
• Pretrial and precharge supervision programs,
• Programs to reduce recidivism of controlled substances offenders on probation or supervised release or participating in drug courts,
• Support local participation in drug court initiatives approved by the Judicial Council.

The Ounce of Prevention Fund of Florida supports innovative programs aimed at enhancing the well-being of at-risk children and families. Established in 1989, it emphasizes prevention and community engagement. Funded initiatives may address issues like unintended pregnancies, substance abuse, and educational improvement. Projects must demonstrate sustainability and community support, with funding cycles lasting up to five years. The focus is on culturally relevant, family-centered approaches that promote healthy development and positive outcomes for children.

About the Department of Health Services (DHS)

The Department of Health Services (DHS) is one of the largest state agencies in Wisconsin, with an annual budget of roughly $15 billion and more than 6,700 employees. DHS is committed to protecting and promoting the health and safety of the people of Wisconsin, making sure everyone can live their best life.

Wisconsin Alcohol Policy Project

The Division of Care and Treatment Services is seeking applications for funding to provide statewide and Wisconsin-specific alcohol prevention and policy education, training, and technical assistance. This includes providing education and information on alcohol-related trends, gaps, and opportunities and providing guidance and implementation of evidence-based and environmental strategies and policies to prevent and reduce underage drinking, alcohol misuse, and binge drinking.

Program requirements

The intention of the Wisconsin Alcohol Policy Project is to provide training, tools, and technical assistance to municipalities, law enforcement, public health, and community coalitions working to improve the alcohol environment and reduce alcohol-related problems. 

Johnson County Community Development Office

The mission of the Johnson County Community Development Office is to secure federal, state and local funding for community development activities, to provide leadership in coordinating these activities, and to ensure continued funding through accountable, efficient and effective use of these funds in serving low- to moderate-income residents in Johnson County.

Community Development Block Grant

The Community Development Block Grant (CDBG) program provides annual grants on a formula basis to states, cities, and counties to develop viable urban communities by providing decent housing and a suitable living environment, and by expanding economic opportunities, principally for low- and moderate-income persons. The program is authorized under Title 1 of the Housing and Community Development Act of 1974.

Federal Objective

The primary objective of Title I of the Housing and Community Development Act of 1974, as amended, is to promote “development of viable urban communities, by providing decent housing and a suitable living environment and expanding economic opportunities, principally for persons of low and moderate income.” The Code of Federal Regulations, 24 CFR 570 Subparts A through O, govern how this objective is to be carried out.

Johnson County’s Priority Objectives

The primary goal of the program is to provide federal financial assistance to eligible applicants for the purpose of community development. In pursuit of this goal, the County has identified several strategies in the Plan that applicants should consider when applying. A unit of local government may also use local goals and/or objectives in support of a specific activity for which funds are requested. As stated in the 2025-2029 Consolidated Plan, the priority needs are: Non-Housing Community Development; Affordable Housing; and Homelessness.

The CDBG program includes funding for: 1) Housing Projects; 2) Public Facilities Projects 3) Public Services Projects; and 4) Economic Development Projects

Public Services Projects

Eligible Activities

Once the National Objective is determined then the activity must be a public service as defined at 24 CFR 570.201(e). Provision of public services, including but not limited to those concerned with employment, crime prevention, childcare, health, drug abuse, education, fair housing counseling, energy conservation, welfare, homebuyer downpayment assistance or recreational needs.

Caring For Denver Grants focuses on community-centered solutions addressing mental health and substance misuse in Denver. The initiative prioritizes equitable access to culturally relevant care, emphasizing the importance of community-based organizations. By supporting peer specialists and care navigation, the foundation aims to improve access and outcomes for marginalized populations. Grant applicants must be nonprofit organizations or government entities serving Denver residents. This funding opportunity seeks to uplift voices affected by historical trauma and promote innovative approaches to mental health care.

About Us

The Foundation for a Healthy Kentucky (FHKY) is a nonprofit organization funded by an endowment that aims to transform our state so that every Kentuckian has what they need to live a healthy life. Since it opened its doors in 2001, the Foundation has invested millions in health policy advocacy, research, and demonstration projects across the Commonwealth.

Partnerships for Success Grants

Partnerships for Success (PFS) provides funding to enhance and support Kentucky community-based organizations that serve communities with limited opportunities. Applicants should focus on reducing alcohol, nicotine (including vaping), and cannabis use/misuse and related consequences by implementing evidence-based prevention programs, practices, and policies that are trauma and resilience informed, and responsive to local and community context. The Foundation for a Healthy Kentucky (FHKY) is facilitating this funding opportunity as one of its pass-through grant programs. The project is supported by the Kentucky PFS 2023 Grant via the Substance Abuse and Mental Health Services Administration (SAMHSA) Grant H79SP083680.

Grants will provide up to $50,000 in funding for 12 months. 

Goal

To provide funding that enhances and supports evidence-based strategies to prevent alcohol, nicotine (including vaping), and cannabis use/misuse in communities that are at higher risk in Kentucky.

Overview

This funding opportunity allows potential grantees to creatively address localized behavioral health-related issues. Funding is intended to support solutions that address the issues, identified by those who live and work locally, as most relevant to communities that are at higher risk in Kentucky.

Proposed projects should:

• Focus on communities with limited opportunities as the primary focus of a proposed or existing project or program, including leadership and decision-making power.
• Make communities that are at higher risk the primary beneficiaries of the project or program's outcomes.
• Address a substance use challenge identified by the community.
• Plan, develop, implement, and/or sustain a prevention initiative.

The Cass County Opioid Settlement Funds provide crucial financial resources to address opioid-related issues in Michigan. Originating from a $26 billion settlement, nearly $800 million will be allocated over 18 years, with half directed to local governments. Priority funding areas include naloxone distribution, treatment for pregnant women, and support for incarcerated individuals. Additional settlements are expected to enhance resources, emphasizing the importance of community support and addressing the needs of underserved populations impacted by the opioid crisis.

Granite United Way administers the Opioid Abatement Community Grants Program (OACGP) to combat the opioid crisis in New Hampshire. This initiative allocates $10 million over two years to support community-based prevention, treatment, and recovery efforts. Eligible applicants include nonprofits, municipalities, and governmental entities dedicated to improving community well-being. The program aims to create lasting positive change by addressing critical health and social issues related to opioid abuse.

What is Granite United Way?

Granite United Way is a nonprofit organization that makes strategic investments in our community to help people learn, earn, and be healthy. Our impact covers more than 85% of New Hampshire and Windsor County, Vermont. With the support of more than 22,000 donors and volunteers, we are working together to provide more than $14 million in support to over 400,000 individuals.

If you are concerned about issues in our community like homelessness, education gaps, and health disparities, you're not alone. Many of us want to make a meaningful difference, but aren't sure where to start.

At Granite United Way, we streamline that process by connecting your support to the most pressing issues in our community. We remove barriers and create opportunities for people to make a positive impact in our community. When you partner with us, you help meet critical needs and create a ripple effect of positive change throughout our community.

Opioid Abatement Community Grants Program (OACGP): Short-Term Responsive Grants

ranite United Way (GUW) administers the Opioid Abatement Community Grants Program (OACGP) on behalf of the New Hampshire Department of Health and Human Services and the Opioid Abatement Advisory Commission. Through this program, $10 million in settlement funds will be invested over two years to support community-based efforts that prevent, reduce, and address the harms of the opioid crisis across New Hampshire. OACGP supports programs, partnerships, and community-led work that strengthen prevention, treatment, recovery, and long-term wellbeing. Funding is available to nonprofit organizations, municipalities, school districts, and other eligible entities serving New Hampshire communities.

Grant Opportunities

• Short-Term Responsive Grants:
  • Up to $15,000 for timely projects that address emerging needs, fill gaps, or strengthen community capacity.

The Cass County Opioid Settlement Funds aim to support organizations addressing opioid use through prevention, treatment, and community support initiatives. The funding prioritizes services for individuals and families affected by opioid use, focusing on racial equity and youth prevention. Grants are available for both emergency and non-emergency interventions, ensuring a fair and transparent process for fund allocation. This initiative seeks to make a significant impact on the community by addressing unmet needs and leveraging collaboration with local service providers.

The Adams County Opioid Settlement Fund aims to address substance use disorders by administering settlement funds to support impactful community projects in Adams County, Illinois. The committee prioritizes core abatement strategies, including naloxone distribution, medication-assisted treatment, and prevention programs. Non-profit and for-profit entities serving the county are eligible to apply, with a focus on projects benefiting local residents. Sustainability and compliance with legal requirements are essential to ensure long-term impact.

The Georgia Opioid Crisis Abatement Trust aims to eradicate and prevent the opioid crisis in Georgia through collaborative efforts. Established to manage funds from national settlements with opioid manufacturers, the Trust supports addiction prevention, treatment, and recovery services. This initiative aligns with Georgia's strategies for addressing the opioid crisis, inviting eligible organizations to participate in vital programs that promote healing and safeguard future generations.

Nonprofit and community partners in Arizona working on trauma-informed substance use prevention can apply for up to US $200,000 to support primary prevention programs. With a mission to strengthen protective factors, the Arizona Governor's Office of Youth, Faith and Family provides addiction and substance use organizations with funding to address root causes and build healthier, safer communities.

The Chaney Family Foundation Grants aim to enhance the welfare of children and families while promoting public safety in Barry County, Missouri; Cabell County, West Virginia; and Jackson & Josephine Counties, Oregon. Grants up to $15,000 are available for West Virginia organizations, while those in Oregon and Missouri can apply for up to $10,000, focusing on human services, faith-based programs, and public safety initiatives.

The Reliant Foundation Community Grants support charitable initiatives from 501(c)3 non-profits in Central and MetroWest Massachusetts. Priority is given to programs addressing substance use disorders and mental health services for youth. Collaborations aligned with Community Health Improvement Plans are encouraged. Grants are not available for individuals, for-profit businesses, or funding specific salaries. This initiative aims to enhance the health and wellbeing of all community members.

The OneOhio Recovery Foundation is dedicated to addressing the opioid epidemic by allocating funds from pharmaceutical settlements to enhance substance misuse prevention, treatment, and recovery initiatives across Ohio. For Regional Grant Cycle #2, the Board authorized $40 million to support evidence-based investments in local communities. This funding model aims to create sustainable impacts while ensuring fiscal responsibility and transparency in managing resources for long-term recovery efforts.

Delaware Division of Substance Abuse and Mental Health

The Delaware Division of Substance Abuse and Mental Health (DSAMH) recognizes the need to leverage local community expertise to reach and impact the wide array of communities that continue to be impacted by the opioid overdose crisis. DSAMH also acknowledges that not all communities have been or are impacted equally. Although there have been recent improvements in drug overdose deaths, significant work remains. DSAMH is committed to offering multiple ways to partner with communities to prevent overdose, reduce the impact of opioid and stimulant use disorders, and improve access to prevention, treatment, and recovery services across Delaware.

ECASU Community Awareness Partnerships

Through the federal State Opioid Response (SOR) Grant, the Engaging Communities in Addressing Substance Use (ECASU) initiative offers three opportunities for organizations and community leaders working to address OUD/STUD in Delaware:

• Messaging Campaigns (ECASU-MC)
• Mini-Grants (ECASU-MG)
• Community Awareness Partnerships (ECASU-CP)
  • The ECASU Community Awareness Partnerships (ECASU-CP) provide technical assistance to community-based, grassroots, advocacy, faith-based organizations, community coalitions, community leaders, and treatment providers (collectively referred to as Community Partners) to directly engage members of the community to educate, increase awareness, and provide resources for OUD/STUD. These strategies can include, but are not limited to, in-person events, educational sessions, social media strategies, video campaigns, and listening sessions. Below are the focus areas of DSAMH’s current campaign strategies, which require a focus on opioid and stimulant use, that can be supported by DSAMH and its technical assistance vendors for partners to refine and implement within their own communities.
    • Reduced stigma toward persons with OUD/STUD
    • Promoting awareness of and access to OUD/STUD treatment and recovery services
    • Reducing stigma toward medications for opioid use disorders, such as methadone and buprenorphine
    • Promoting access to naloxone/Narcan
    • Increasing awareness and knowledge of existing resources among local communities 

The Evergreen Foundation Grant supports not-for-profit organizations in Western North Carolina that provide essential services for individuals with behavioral health, intellectual, and developmental disabilities. Established in 1977, the Foundation allocates funding through a competitive grant process, typically issuing 25 to 30 grants annually. Eligible applicants include agencies serving these populations and those with 501(c)(3) status. Priorities include infrastructure support, education, and advocacy, ensuring vital services reach the communities in need.