Best South Dakota Grants for Nonprofits

The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network aims to tackle significant challenges in multi-center clinical trials. By enhancing trial efficiency and safety through innovative solutions, the initiative seeks to improve the design and execution of these studies. Key areas of focus include safety monitoring tools, trial leader mentorship, and advancements in digital health technologies. This program invites eligible organizations to apply for funding to promote groundbreaking clinical research.

The Limited Competition Research Education Program for the Clinical and Translational Science Awards Program aims to enhance the training of a workforce to meet the nation's biomedical and clinical research needs. It supports educational activities that facilitate the translation of scientific discoveries into practical health interventions. Funded by the NIH, this program invites applications from eligible organizations, and only those with meritorious proposals will be considered for funding.

The Clinical and Translational Science Awards (CTSA) Program aims to expedite the integration of scientific discoveries into effective health interventions. By providing essential infrastructure and support to academic medical centers, the program fosters innovative research approaches that enhance translational science. The Collaborative and Innovative Acceleration Award under this initiative seeks to promote partnerships that accelerate the development of new treatments, ultimately improving health outcomes for diverse populations.

The Limited Competition for High Impact Specialized Innovation Programs aims to enhance clinical and translational science by funding unique capabilities and addressing critical gaps through the Clinical and Translational Science Award (CTSA) Program. This initiative fosters collaboration across a national network of academic medical centers, facilitating the transition of scientific discoveries into impactful health interventions. Applications are peer-reviewed, ensuring funding is directed towards the most promising proposals.

Eastern Carolina Community Foundation

Eastern Carolina Community Foundation, founded in 2006, is the newest community foundation in South Carolina. We have a permanent endowment to meet the changing needs of the Pee Dee.

Eastern Carolina Community Foundation improves the quality of life in our area of South Carolina through inspired philanthropy and innovative community programs. We serve Chesterfield, Darlington, Dillon, Florence, Marion, Marlboro, and Williamsburg Counties.

Scholarships

Eastern Carolina Community Foundation partners with donors to administer 12 scholarship funds for the benefit of students in the Pee Dee. All scholarship opportunities are established through specific funds established at ECCF with criteria determined by the donor. 

The Michelle Yolanda Glenn Carey Scholarship

This fund provides a scholarship to a graduating Pee Dee area high school senior who plans to major in education and teach at the elementary level. The fund was established in memory of Michelle Yolanda Glenn Carey who dedicated twenty years to the teaching of kindergarten students at Theodore Lester Elementary School in Florence, South Carolina.

The Minnesota Nurses Association Foundation (MNAF) offers scholarships to support nursing professionals and students. With a commitment to healthcare quality, MNAF empowers MNA members, their families, and veterans to pursue their educational goals. The scholarships enhance nursing practice and leadership, ensuring access to quality healthcare for all. MNAF's mission reflects a dedication to social justice and public health, promoting the welfare of nurses and the communities they serve. Applications are welcomed from eligible candidates seeking to advance their nursing careers.

Washington County Community Foundation

The Washington County Community Foundation seeks to improve the quality of life in Washington County by promoting and facilitating philanthropy. We accomplish this by assuming four philanthropic roles of Grantmaker, Donor Service Organization, Fundraiser, and Community Leader. 

Fostering philanthropy by offering charitable gifting opportunities to donors on an individualized basis and at reasonable fees, we make charitable giving easier, more satisfying, and more effective. We broadly support the Washington County community by awarding grants in eight focus areas as follows: Animal Welfare, Arts & Humanities, Community Improvement & Economic Development, Conservation & Environment, Education, Health & Fitness, Human Needs, and Religion & Faith.

Loughman Scholarship Fund

For a current year graduating senior who resides within the boundaries of the Fort Cherry School District, who plans to enroll in an associate or bachelor’s degree program, and who demonstrates financial need. 

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

George F. and Asha W. McMillan Scholarship

This scholarship is to provide financial support to an individual in order for him or her to receive a degree in Christian education or related studies or to advance his or her Christian vocation.

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

George and Helen Stowell Scholarship (Medical)

Applicant must be a graduating senior of any Henderson County public high school who is also a native of Henderson County and is pursuing a career in a health-related field, other than a physician. 

Community Foundation of Henderson County

Community Foundation of Henderson County was incorporated in 1982 by a group of fourteen dedicated and compassionate local leaders with the immediate need to manage two funds - the William C. Armstrong Scholarship Fund and the Charlie Renfrow Scholarship Fund, in addition to providing a permanent vehicle for citizens to give back to their community.

Our Mission is to help people who care make lasting contributions to causes that matter. The Community Foundation of Henderson County is a highly visible, philanthropic leader directed by an engaged and committed board, staffed by qualified employees, empowering donors at all levels to invest in professionally managed charitable funds that address community needs.

George and Helen Stowell Scholarship (General)

Applicant must be a graduating senior of any Henderson County public high school who is also a native of Henderson County. 

The Planetary Science Enabling Facilities (PSEF) program by NASA invites proposals for research facilities that support the Planetary Science Division. It aims to enhance scientific collaboration and innovation by providing resources to a diverse range of institutions, including emerging and undergraduate colleges. Proposals should highlight the scientific merit and community need for these facilities, ensuring that they serve a broad user base committed to advancing planetary science.

About 

Epilepsy Wellness Advocates (EWA) is a privately funded, research-informed organization focused on improving the quality of life for people living with epilepsy through collaborative partnerships and wellness-centered initiatives.

Free from pharmaceutical or institutional influence, we are committed to developing and supporting unbiased, evidence-based approaches to epilepsy management. Our efforts center on empowering individuals, families, and the organizations that serve them with practical tools, education, and support.

Epilepsy management extends far beyond clinical settings. Together with our partners, we’re building new ways to live well with epilepsy.

Epilepsy Wellness Advocates Research Grants

Epilepsy Wellness Advocates is dedicated to improving the quality of life for people with epilepsy by funding innovative research, and impactful programs with our long-term strategic partnerships for epilepsy management through alternatives to pharmacological or surgical avenues.

We collaborate with leading organizations, researchers, and wellness providers to understand and develop integrative and wellness health solutions that enhance the daily lives of those living with epilepsy. Our goal is to enable our partners and providers to impact as many people with epilepsy as possible and provide them with the tools and resources they need to reduce the impact of epilepsy on people’s lives.

Categories of Grant Funding:

• Epilepsy Integrative Wellness Programs
• Epilepsy Integrative Wellness Research Studies
• Epilepsy Education and Toolkit Programs
• Epilepsy Education Scholarships & Education Emergency Supports

Program Outcomes of Grants:

• Improve quality of life and functional outcomes for people with epilepsy (PWE) and their caregivers.
• Reduce seizure frequency, severity, and overall seizure burden through evidence-informed approaches.
• Advance personalized, whole-person epilepsy management that reduces reliance on trial-and-error care.
• Increase access to epilepsy wellness information, programs, and tools for PWE, caregivers, and providers.
• Empower caregivers as essential partners by strengthening their education, tools, and ability to navigate care systems.
• Translate research into practical, day-to-day resources that improve real-world epilepsy management and decision-making.
• Drive innovation in epilepsy wellness and integrative care, including the development and validation of scalable management models.
• Address comorbidities, side effects and other treatment burdens, and lifestyle factors that materially affect epilepsy outcomes and daily functioning.
• Strengthen the epilepsy workforce and future provider pipeline, ensuring providers understand and are trained to treat epilepsy as a whole-person condition.
• Reduce stigma and social isolation that negatively impact independence, dignity, and participation for PWE.

The National Bycatch Reduction Engineering Program (BREP) for FY2026/27 offers competitive grants aimed at supporting non-Federal researchers. This initiative, governed by the Magnuson-Stevens Fishery Conservation and Management Act, focuses on developing innovative fishing practices and gear technologies to minimize bycatch and reduce post-release mortality of non-target species. By addressing bycatch reduction, the program seeks to enhance the sustainability of U.S. fisheries and aquaculture, aligning with the National Marine Fisheries Service's conservation goals.

The Cooperative Endangered Species Conservation Fund supports habitat conservation through land acquisition grants. Established in 1997, this program aims to minimize conflicts between listed species conservation and land use. The U.S. Fish and Wildlife Service provides matching grants to state agencies for projects that ensure the long-term protection of habitats. By acquiring land or conservation easements, this initiative facilitates species recovery and helps prevent future listings under the Endangered Species Act, enhancing overall ecosystem health.

The Assisting Specialty Crop Exports initiative aims to enhance U.S. specialty crop market access by developing low-oxygen storage and packaging systems for tree nuts. By addressing phytosanitary requirements and pest control, the initiative supports producers in maintaining product quality while complying with international standards. This funding opportunity from the Foreign Agricultural Service encourages innovative solutions that can improve export processes and reduce reliance on costly fumigation methods, ultimately benefiting U.S. agribusiness and ensuring competitiveness in global markets.

The Tribal Colleges Education Equity Grants Program aims to enhance educational capacity in food and agricultural sciences for Native Alaskan and American Indian students. This initiative marks the start of a new four-year funding cycle focused on key priorities such as curriculum development, faculty training, student experiential learning, and essential teaching tools. By fostering recruitment and retention, the program seeks to strengthen strategic partnerships within tribal education systems.

The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.

The Small Instruments and Modern Equipment program invites shared-use biomedical research facilities to apply for funding to purchase small instruments or scientific equipment. These resources, which may include core facilities and biorepositories, aim to enhance operational efficiency and support the use of innovative technologies. Funding is specifically targeted for instruments that produce outputs beyond traditional digital data, excluding highly specialized or building-level infrastructure equipment.

The Children and Youth with Special Health Care Needs Research Network aims to enhance the lives of children and youth with special health care needs (CYSHCN) and their families. By establishing a robust research infrastructure, the program will generate evidence-based solutions to foster well-being and community engagement. It focuses on identifying effective interventions and measures that can be integrated into essential services and supports, ultimately helping CYSHCN thrive throughout their lives.

The Regional Excellence for Access to Comprehensive Care for Hemophilia Networks (REACH Networks) aims to enhance access to coordinated, evidence-based care for individuals with hemophilia and related disorders. This initiative will broaden access to comprehensive care, implement quality improvement projects, and provide ongoing training and education for Hemophilia Treatment Center staff. The focus is on improving best practices for comprehensive, collaborative care, including effective lifespan transitions for patients.

About Americans for the Arts

Building Collective Power for the Arts

Americans for the Arts is the nation's leading arts advocacy organization. We mobilize advocates, produce trusted research, and secure bipartisan wins that protect funding and expand arts access nationwide — work we've been doing for more than 65 years.

Americans for the Arts advances the people, organizations, and systems supporting arts and culture across America through advocacy, research, and national convening.

We envision a nation where freedom of creative expression is upheld as a fundamental human right, where arts and culture are woven into the fabric of civic life, resourced in every community, and accessible to everyone.

Request for Proposals (RFP)

Strengthening Leadership Capacity of Local Arts Agencies

Given the essential role of LAAs, and to meet this important moment, AFTA seeks an energized and experienced consulting team with expertise to help it develop a comprehensive strategy to strengthen leadership and field capacity across the LAA ecosystem. This work is not intended to operate in isolation, but rather to complement and build upon existing efforts already underway in the field. The focus is on identifying where AFTA can add value through targeted, strategic support that enhances and aligns with broader sector-wide initiatives. 

This effort will focus on empowering LAA agency leaders—a critical component of AFTA’s strategic direction—to expand their capacity, foster innovation, and advance equity in a rapidly evolving environment. Building on existing efforts across the field, AFTA will invest in strong, effective LAA leadership, broaden cultural access and participation nationwide, and position the field for a more vibrant, resilient, and sustainable future. 

With approximately 2,200 LAAs nationally validated in AFTA’s LAA Wayfinder, the selected consulting team will help AFTA gain a deeper understanding of the gaps, needs and opportunities shaping LAA leadership capacity, with attention to Native, rural, small, midsize, and large communities, and identify where AFTA is uniquely positioned to contribute. These insights will guide AFTA’s future direction in its service to LAAs nationwide and ensure AFTA’s contributions complement—rather than duplicate—the work of other entities, collectively strengthening the broader LAA ecosystem.  

In addition, by intentionally working in partnership with peer organizations and stakeholders across the field—and by understanding gaps in coverage and opportunities for growth—AFTA will be positioned to work with partners to support the expansion of the LAA network in communities where local public cultural infrastructure is limited or absent. This collaborative approach will help ensure more equitable access to arts and culture while reinforcing the role of LAAs as essential community anchors, particularly in underserved regions. 

About the Foundation

There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.

Our Mission

Promote the mental health and well-being of individuals and communities.

Our Vision

A mentally healthy nation for all – where we live, learn, work, worship, and play.

Psychiatric Research Fellowship

The Psychiatric Research Fellowship provides funding for an early research career psychiatrist to design and conduct a health services/policy-related research study using national data housed at the APA. The Fellow's research activities will be carried out under the supervision and guidance of a mentor at his/her institution in collaboration with his/her mentor(s) at the APA Division of Research. This vital program will enable the APA and APA Foundation to actively participate in sustaining and strengthening the clinical investigators workforce specifically in psychiatry.

Program Benefits

• Receive funding (up to $45,000 per year) towards a research study that will address a major research topic impacting psychiatric practice.
• Receive mentorship from established researchers in the field of psychiatry in the design and implementation of his/her research study.
• Access to secondary national data (e.g., CMS Claims data; APA Registry data) to carry out his/her research study.
• Present his/her research at one or more APA meetings.
• Opportunity to attend additional meetings that provide further mentorship in psychiatric research (e.g., Early Research Career Breakfast).
• Have access to a lifetime network of APA member experts working in the field of psychiatric research.
• Establish relationships and peer-mentorship with a diverse group of residents and fellows with similar career interests and goals.
• Participate on an assigned APA Council or APAF initiative where organizational decisions are made.
• Gain an understanding of APA Governance through service on an APA Council, Committee or APAF initiative.
• Appear in the APA Convocation of Distinguished Fellows Program Book listings.

The BJA FY 2026 Edward Byrne Memorial Justice Assistance Grant (JAG) Program—State Formula aims to enhance public safety through formula funding to states. This initiative supports hiring personnel and acquiring vital resources for law enforcement and criminal justice systems. Eligible state agencies can apply for grants to address various public safety challenges, including violent crime and human trafficking, ensuring the protection of American citizens. Applications are due by September 25, 2026.

The BJA FY 2026 Crisis Response Training Program aims to enhance public safety and law enforcement effectiveness by providing critical training for officers in responding to individuals experiencing behavioral health crises. This funding opportunity supports state, local, and tribal governments in developing programs to improve responses to those with mental health conditions, intellectual disabilities, and other challenges. By equipping officers with essential skills and strategies, the program seeks to ensure safer interventions and better outcomes in crisis situations.

The BJA FY 2026 Edward Byrne Memorial Justice Assistance Grant (JAG) Program offers formula funding to support local governments in enhancing public safety. This grant aids in hiring personnel, purchasing essential equipment, and providing training and technical assistance to address crime and safety challenges. Applicants are encouraged to verify their eligibility for direct JAG funding from BJA before submitting their applications. The deadline for full applications is October 16, 2026, at 8:59 p.m. ET.

The National Institute on Minority Health and Health Disparities (NIMHD) is offering funding for innovative research aimed at improving health outcomes for Native Hawaiian and Pacific Islander populations. This grant will support preparatory and pilot activities that focus on understanding health disparities, testing interventions for chronic diseases, and promoting health behavior changes in collaboration with community partners. Projects should address critical health issues such as cancer, diabetes, and maternal health.

Pediatric Dermatology Research Alliance Inc 

PHACE syndrome is a neurocutaneous syndrome characterized by large segmental infantile hemangiomas of the face and scalp in association with congenital anomalies that may affect the posterior fossa of the brain, cerebral and cervical arteries, heart, and/or eyes. LUMBAR syndrome is the lower-body counterpart of PHACE, characterized by large segmental infantile hemangiomas of the lumbosacral, buttock or pelvic regions associated with urogenital, spinal, bony, anorectal, and/or renal abnormalities. Those affected experience a wide range of comorbidities with significant psychosocial impact. We invite proposals for clinical research that improves diagnostic approaches, enhances quality of life, and addresses key aspects of disease burden and management.

Applications may be submitted by either a single investigator or multiple investigators at multiple institutions. A total of $40,000 is available and may be awarded as one large-scale project or as multiple smaller awards, depending on the number and quality of applications received. Equal consideration will be given to projects in either of the two award formats with decisions to be based upon merit and available funds.

Focus

Research should focus on PHACE and/or LUMBAR syndromes. Priority will be given to investigators who have not previously served as the senior investigator on an R01 NIH grant or equivalent, and to studies that include multidisciplinary teams with active roles for early-career investigators. Proposals that meaningfully integrate patient perspectives are strongly encouraged.

Important Details

• Up to $40,000 will be funded to support one large-scale project for up to two years, or as multiple awards for smaller-scale projects