Skip to main content
Main content

Best South Dakota Grants for Nonprofits

Find nonprofit grants in South Dakota, including opportunities in Sioux Falls, Rapid City, and Aberdeen. Updated listings for 501(c)(3) organizations statewide.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,297 Results based on applied filters

GEMSSTAR for Emergency Medicine Supplemental Funding Program

Society for Academic Emergency Medicine Foundation
Private
United States
Up to US $25,000
The GEMSSTAR for Emergency Medicine Supplemental Funding Program provides up to $25,000 over two years to support emergency medicine physicians who have received the NIA GEMSSTAR grant. This program aims to enhance the Professional Development Plan of GEMSSTAR awardees, ensuring they receive the necessary funding for their research endeavors. Eligibility is limited to those who have completed their clinical specialty training and are based at U.S. institutions, with funding contingent upon available resources.
Emergency Medical Care & Services Aging / Gerontology Dental Health +2 more

ASTRO-BCRF Emerging Investigator Award

American Society For Radiation Oncology
Association/Society
United States
Up to US $100,000
The ASTRO-BCRF Emerging Investigator Award aims to support one early career researcher in breast radiation oncology from underrepresented populations. This initiative by the American Society for Radiation Oncology and the Breast Cancer Research Foundation provides $100,000 for direct costs over one year, emphasizing diversity in the scientific workforce and encouraging eligible individuals to self-identify as part of underrepresented groups in biomedical research.
Breast Cancer

ASTRO Residents/Fellows in Radiation Oncology Seed Grant

American Society For Radiation Oncology
Association/Society
United States
Up to US $50,000
The ASTRO Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology through funding basic, translational, and clinical research. It encourages innovative projects that enhance patient care and improve health care delivery, including cancer research and understanding radiation effects on tissues. This grant is supported by the American Society for Radiation Oncology, which seeks to foster impactful research in this vital medical field.
Cancer / Oncology

ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed RFA

American Society For Radiation Oncology
Association/Society
United States
Up to US $50,000
The ASTRO-LUNGevity Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology and its impact on lung cancer treatment. This $50,000 award supports innovative basic, translational, and clinical research projects. A no-cost extension may be granted at ASTRO and LUNGevity's discretion, but the total project duration cannot exceed two years.
Lung Cancer

College Well-Being-Award

American College Health Foundation
Corporate
United States
Up to US $3,500
The College Well-Being Funding Opportunity aims to enhance the health of college students through innovative programs and research. Offered by the American College Health Foundation, it provides up to two awards of $3,500 to eligible institutions for improving campus infrastructure that promotes student well-being. This initiative encourages creativity and collaboration among campus health professionals to develop effective, measurable outcomes in student wellness. By fostering a culture of well-being, the foundation seeks to address the evolving needs of contemporary students.
Education - Higher Education Wellness & Healthy Living

Beth N. Rom-Rymer Travel Scholarship for Native Psychology Students

American Psychological Foundation Inc
Private
United States
US $1,000
The Beth N. Rom-Rymer Travel Scholarship provides $1,000 for Native psychology graduate students to attend the American Psychological Association's annual convention. This opportunity is specifically for members of the Society of Indian Psychologists (SIP). The scholarship aims to support diverse applicants and encourages first-time attendees who demonstrate financial need. APF, the funding organization, is dedicated to enhancing the field of psychology by supporting early career professionals and their contributions to societal improvement.
Native American Services Psychology

Drug Discovery Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Drug Discovery Predoctoral Fellowship by the PhRMA Foundation supports PhD candidates engaged in thesis research in drug discovery. This fellowship offers $30,000 annually for 12 to 24 months, encouraging innovative research that integrates multiple scientific disciplines. Applicants must be full-time, in-residence students at accredited U.S. universities and have completed significant coursework. The funding is conditional upon continued enrollment and is intended for stipend support, with some funds allowable for research-related incidentals.
Pharmacology

Drug Delivery Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Drug Delivery Predoctoral Fellowship by the PhRMA Foundation supports promising PhD candidates in drug delivery research at accredited U.S. universities. It provides $30,000 per year for 12 to 24 months, aimed at enhancing the understanding of drug formulation and delivery technologies. The fellowship emphasizes innovative research that leads to improved patient outcomes and fosters collaboration among diverse research teams, ensuring that all individuals have access to groundbreaking medicines.
Pharmacology

Drug Delivery Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The PhRMA Foundation offers a Drug Delivery Postdoctoral Fellowship aimed at fostering biopharmaceutical innovation and enhancing research capabilities in drug delivery. This fellowship supports both U.S. and non-U.S. citizens who are involved in collaborative research training at accredited U.S. universities. Awardees receive a stipend of $60,000 per year for 12 to 24 months, with funding contingent on ongoing employment in the postdoctoral program. Ideal candidates are encouraged to expand their skills in new research environments.
Pharmacology

Drug Discovery Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The Drug Discovery Postdoctoral Fellowship by the PhRMA Foundation supports researchers in a multidisciplinary training program at accredited U.S. universities. Aimed at enhancing credentials in drug discovery, it funds innovative research with potential human applications. Proposals should focus on biological validation of drug targets across various scientific disciplines. The fellowship provides $60,000 in annual stipend support for up to 24 months, contingent on the awardee's continued employment at the university.
Pharmacology

Drug Discovery Faculty Starter Grant

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
US $100,000
The Drug Discovery Faculty Starter Grant, offered by the PhRMA Foundation, supports early-career researchers in drug discovery at U.S. universities. With a funding amount of $100,000 for one year, this grant is targeted at faculty members within five years of their independent status. The program aims to foster innovative research that integrates various scientific disciplines, ultimately leading to novel treatments for patients. Eligibility extends to full-time faculty members eligible for promotion.
Pharmacology

Drug Delivery Faculty Starter Grant

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
US $100,000
The Drug Delivery Faculty Starter Grant from the PhRMA Foundation supports early-career researchers in drug delivery, providing $100,000 for one year. Eligible applicants include full-time faculty at accredited U.S. universities within their first five years of independent status. The grant emphasizes innovative research that enhances drug transport and dosage forms. Recipients must notify the Foundation of any external funding exceeding $250,000. This initiative aims to foster scientific independence and collaboration in biopharmaceutical innovation.
Pharmacology

SUS: Mid Career Award

Society of University Surgeons
Private
Canada, United States
US $40,000
The SUS Mid Career Award offers $40,000 for one year to SUS members in the US or Canada with prior research funding, supporting their ongoing work in surgical sciences. Eligible applicants must have experience as a principal investigator on independent or smaller grants, or hold a career development award. This award serves as bridge funding for those who have recently applied for independent grants but were not funded, fostering continued research and innovation.
Surgery

SUS: Resident Research Scholar Award

Society of University Surgeons
Private
Canada, United States
US $30,000
The SUS Resident Research Scholar Award offers $30,000 for one year to surgical residents engaged in basic or translational research. Eligible candidates must have completed two years of training and commit to full-time research with an SUS member. Notably, applicants must avoid mentors on the exclusion list, ensuring a fair and competitive application process. This funding promotes innovative surgical research and supports the development of future leaders in the field.
Surgery Bioengineering Health Information Technology +1 more

American Surgical Association: Surgical Leaders Fellowship Grant

American Surgical Association
Private
United States
US $5,000
The American Surgical Association's Surgical Leaders Fellowship Grant aims to develop future academic surgical leaders while promoting diversity in leadership roles. The program includes shadowing experiences and skill development, allowing fellows to assess their readiness for leadership positions in surgery. Each fellowship provides $5,000 in funding for visits to two academic institutions, enhancing professional growth through mentorship with established leaders in the field.
Surgery

FFAR Fellows: Stipend + Professional Development Category

Foundation for Food and Agriculture Research (FFAR)
Private
Canada, United States
Up to US $148,500
The FFAR Fellows Program offers professional development and leadership training for PhD students in food and agriculture sciences across the U.S. and Canada. Led by North Carolina State University, the program includes in-person meetings, virtual sessions, and mentorship opportunities. Students receive a combined stipend of $65,000 annually, with a minimum of 50% sponsorship from non-academic sources. The program emphasizes interdisciplinary collaboration, career exploration beyond academia, and the development of essential skills for future leaders in the field.
Agriculture

FFAR Fellows: Professional Development Category

Foundation for Food and Agriculture Research (FFAR)
Private
Canada, United States
US $15,000 in in-kind support
The FFAR Fellows Program, led by North Carolina State University, provides PhD students in food and agriculture sciences with essential leadership and professional development training. Over three years, fellows engage in in-person meetings, virtual sessions, and mentorship opportunities, enhancing their skills and networking. Applicants must be enrolled in a PhD program, have a confirmed financial sponsor, and demonstrate readiness to participate. This initiative promotes interdisciplinary collaboration and broadens career pathways beyond academia.
Agriculture

ASES Research Grant

Ases Foundation
Private
North America
Up to US $20,000
The ASES Research Grant, provided by the ASES Foundation, offers up to $20,000 for innovative shoulder and elbow research projects. It invites applications from principal investigators who are orthopaedic surgeons working in North America. The funding supports projects lasting between 12 to 24 months and aims to foster advancements in patient care through research. Applications are limited to one per principal investigator per year, promoting focused and impactful research initiatives.
Kinesiology & Sports Medicine Orthopedics Physical Therapy +1 more

Veterans and Nature Grant

National Environmental Education Foundation
Private
United States
Up to US $10,000
The Veterans and Nature Grant, offered by the National Environmental Education Foundation (NEEF) in partnership with the U.S. Forest Service, aims to engage veterans in outdoor activities that promote physical and mental health. With a funding pool of $100,000, grants of up to $10,000 are available for projects focused on outdoor recreation and wellness activities. Eligible applicants include 501(c)(3) entities partnered with public land organizations, fostering environmental awareness and community involvement.
Military & Veterans Services Outdoor Recreation Parks & Public Spaces

High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The High Priority HIV and Substance Use Research funding opportunity aims to support innovative research that addresses the intersection of HIV and substance use. Researchers are encouraged to submit proposals that include a detailed research plan and preliminary data, exploring new avenues for prevention, treatment, and potential cures for HIV among people who use drugs. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.
HIV / AIDS Addiction & Substance Use Disorders Drug Use Disorder

Changing Aging (CA) Grant

Next50 Foundation
Private
United States
Unspecified amount
The Changing Aging (CA) Grant supports innovative projects aimed at enhancing economic opportunities for older adults and combating ageism. Priorities include advancing digital equity and promoting aging in place for marginalized communities. Funded by Next50, the grant encourages collaboration among nonprofits and requires an equity-focused approach to project design. Organizations may apply for up to three years of funding, with no maximum request limit, although a pre-application call is necessary for larger requests.
Aging / Gerontology Senior Services Social Isolation

Growing Convergence Research

National Science Foundation (NSF)
Federal Government
United States
US $1,200,000 - US $3,600,000
The Growing Convergence Research (GCR) initiative by the National Science Foundation (NSF) promotes innovative solutions to complex societal and scientific challenges through multidisciplinary collaboration. By integrating diverse expertise, GCR aims to address specific problems and foster new research paradigms. Proposals must outline a five-year plan, divided into two phases, with budgets not exceeding $1.2 million for Phase I and $2.4 million for Phase II. Successful projects are expected to lead to transformative advances in science and technology.
Cognitive Science Biological Anthropology Engineering +5 more

MRF Breakthrough Consortium (MRFBC) Young Investigator Team Award to Advance the Field of Translational Immuno-Oncology

Melanoma Research Foundation
Private
United States
Up to US $150,000
The MRFBC Young Investigator Team Award supports innovative research in immuno-oncology for melanoma, offering up to $150,000 annually for two years. This funding targets U.S.-based researchers aiming to enhance clinical outcomes for melanoma patients or deepen the scientific understanding of immuno-oncology. The MRF collaborates with key institutions to address challenges in melanoma research, fostering partnerships that maximize research potential and impact.
Cancer / Oncology Skin Diseases & Dermatology Pediatric Cancers

Career Transition Fellowships: U.S. Institutions

National Multiple Sclerosis Society
Association/Society
United States
Unspecified amount
The National Multiple Sclerosis Society offers Career Transition Fellowships aimed at fostering young scientists in MS research. This program supports postdoctoral trainees with a doctoral degree and exceptional potential, providing funding for advanced training and faculty support over five years. Applicants must demonstrate relevance to high-priority research questions outlined in the Society's Pathways to Cures Roadmap, which focuses on stopping MS, restoring function, and ending the disease through prevention.
Multiple Sclerosis

Melanoma: Established Investigator Award

Melanoma Research Foundation
Private
United States
Up to US $125,000
The Melanoma Established Investigator Award offers up to $125,000 annually for two years, aimed at established melanoma researchers or senior researchers transitioning into melanoma research. Eligible applicants include Associate Professors or higher, with both tenured and non-tenured faculty encouraged to apply. U.S. citizenship is not a requirement for this funding opportunity provided by the Melanoma Research Foundation.
Cancer / Oncology Pediatric Cancers Skin Diseases & Dermatology

National MS Society: Postdoctoral Fellowships: U.S. Institutions

National Multiple Sclerosis Society
Association/Society
United States
Unspecified amount
The National Multiple Sclerosis Society offers Postdoctoral Fellowships to support innovative research aimed at advancing the understanding and treatment of multiple sclerosis. These fellowships are designed for promising researchers holding advanced degrees, providing funding for training that enhances their ability to conduct impactful studies. The Society prioritizes applications that align with high-priority research questions outlined in its Pathways to Cures Roadmap, emphasizing the importance of diverse methodologies and engagement with underserved populations.
Multiple Sclerosis

Sidney R. Baer, Jr. Foundation: Education Grants

Sidney R Baer Jr Foundation
Private
United States
Unspecified amount
The Sidney R. Baer, Jr. Foundation focuses on improving the lives of individuals with schizophrenia and bipolar disorder through education grants. By funding programs that enhance educational opportunities, the foundation aims to reduce isolation and promote understanding. Grants are awarded to qualified organizations that prioritize mental health initiatives, ensuring that those affected have access to the resources and support necessary for a better quality of life. The foundation's mission is rooted in the belief that education can be transformative for those facing mental health challenges.
Mental Health & Psychiatric Diseases Schizophrenia Education

South Dakota Grants for Nonprofits Highlights

South Dakota grants for nonprofits provide funding to support rural development, education, public health, and cultural preservation initiatives. The following grants help organizations address community challenges, foster sustainability, and enhance quality of life across South Dakota.


Search Instrumentl's South Dakota Grants Database


Find 106 funding opportunities for nonprofits in South Dakota, with $6.4M available. Instrumentl streamlines the funding process by offering grant-matching tools, deadline alerts, and key insights to help organizations achieve their missions.

Grant Insights : South Dakota Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ South Dakota grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 South Dakota grants for nonprofits over $25K in average grant size

23 South Dakota grants for nonprofits over $50K in average grant size

23 South Dakota grants for nonprofits supporting general operating expenses

91 South Dakota grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for South Dakota grants for Nonprofits?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for South Dakota Grants for Nonprofits?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Frequently asked questions

A wide variety of funding sources for nonprofits are available in South Dakota. Currently, 100+ are available, totaling $6,365,150. For organizations interested in pursuing grant funding in South Dakota, the median grant size is $10,000. Among these grants, 23 grants support general operating expenses while 91 grants fund projects and programs specifically.

Various organizations and institutions provide grants for the state of South Dakota, including government agencies, private foundations, associations, and more. Here’s a breakdown of where you'll find the most grants available:

  • State & Local Government: The state of South Dakota offers over 29 grants. Many of these funding opportunities focus on agriculture.
  • Private Foundations: Around 43 private foundation grants are available in the state of South Dakota, with focus areas ranging from rural development to health and medicine.
  • Corporate Funders: There are around 17 open corporate grants. These grants mainly focus on agriculture and human and social services.

Whether you go after government grants or foundation grants depends on your grant readiness. Keep in mind that government grants often have large awards but equally large compliance requirements.

Based on the data we have now, the best time to apply for grants in South Dakota is in Q1, which is when about 34.7% of grant deadlines fall. This period offers nonprofits the most opportunities to secure funding. Comparatively, Q3 has the least activity, with only 19.8% of deadlines. To maximize your chances of securing funding, be aware of the peak fundraising periods.

The nonprofit funding landscape throughout South Dakota has shown significant activity over the past several years. Based on the funding reports sent to the IRS, overall grant funding reached $481,503,794 in 2021 and then rose to $619,327,674 in 2022, an increase of about 28.62%. Among all the grants awarded in South Dakota, the most popular focus areas for funding were single-organization support from private grantmaking, single-organization support, professional societies, associations and research institutes, and/or public policy analysis. Likewise, the top counties that received the most funding were Pennington County, Minnehaha County and Todd County.

If you want to start finding more grants, Instrumentl simplifies the entire grant process. You can find grants within South Dakota for your nonprofit while also researching funders, managing deadlines, and keeping on top of everything in our all-in-one platform.

With Instrumentl, you'll get access to over 20,000 live grants and 400,000 funders beyond what you see here in South Dakota. Learn more about Instrumentl’s powerful grant platform.

Browse South Dakota Grants by Focus Area

Filter South Dakota Grants by Location

Browse Grants by Counties within South Dakota

Browse Grants by Major US Cities within South Dakota

Explore Grants Outside of South Dakota

Browse Grants by Other States or Regions