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Best South Dakota Grants for Nonprofits

Find nonprofit grants in South Dakota, including opportunities in Sioux Falls, Rapid City, and Aberdeen. Updated listings for 501(c)(3) organizations statewide.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,253 Results based on applied filters

Dr. Martin Luther King, Jr. Regional Scholarship

Bay Area Community Foundation
Private
United States
Approximately US $1,000

About Us

Bay Area Community Foundation is a nonprofit organization created by and for the people of the Bay Area. We offer a range of flexible giving tools to help our donors make a positive impact on the community and causes that align with their interests and passions. In addition to first-rate donor service, we manage our community’s permanent endowment and award grants to address the community’s most pressing needs and promising opportunities.

Since 1982, our community has used our resources to make charitable gifts more effective. We provide maximum flexibility in establishing, managing, and distributing your gifts. Through our donors’ generosity, we can help support arts and culture, community initiatives, education and youth, environment, health and wellness, human services, and recreation in our area.

Dr. Martin Luther King, Jr. Regional Scholarship

Inspired by the belief that love and peaceful protest can eliminate social, political, and economic injustice, Dr. Martin Luther King, Jr., became this nation’s most heralded civil right leader. He aroused blacks and whites alike to protest racial discrimination, war, and poverty. A champion of nonviolent resistance to oppression, he was awarded the Nobel Peace Prize in 1964. Dr. King’s life ended at the age of 39 on April 4, 1968, when he was assassinated in Memphis, Tennessee. However short his life was, he greatly advanced the cause of civil rights in this nation. His life serves as an encouragement to each of us to do all that we can to end injustice.

The Dr. Martin Luther King, Jr. Regional Scholarships are awarded each year to Bay County high school seniors (regardless of ethnicity) who actively embrace Dr. King’s dream of improving racial harmony and social justice. The scholarship award(s) will be at least $1,000 and are non-renewable. The scholarship award(s) will be presented at the annual Great Lakes Bay Regional Martin Luther King, Jr. Celebration program held each January.

This scholarship is also available to Midland and Saginaw County students through their respective community foundations.

Education - High School Academic Scholarship Programs Education - Higher Education +1 more

Multiple Sclerosis Foundation: Transportation Assistance Grant

Multiple Sclerosis Foundation Inc
Private
United States
Unspecified amount

Transportation Assistance Grant

The Transportation Assistance Grant program was established to help members of the MS community remain as independent as possible, and ensure all people with MS have the transportation necessary to get the best medical care.

The program provides funding for reasonable paratransit fees. In partnership with Lyft and Uber, the program can also provide funding for transportation to and from appointments for MS care, limited to neurologist visits and infusion centers, at no cost to the person with MS.

Multiple Sclerosis

Multiple Sclerosis Foundation: Homecare Assistance Grant

Multiple Sclerosis Foundation Inc
Private
United States
Unspecified amount

Homecare Assistance Grant

MS Focus understands the daily needs and challenges that must be met by both those with MS and their caregivers. In order to meet these needs in the most timely and efficient way possible, our Homecare Assistance Grant connects you to the best available local services. Should resources within your community not be available, direct support may be provided on a temporary basis.

Available Services include:

  • Home Care - Personal hygiene services, light housekeeping, grocery shopping, meal preparation, and transportation to and from appointments are all services that can be provided for a limited time.
  • Therapy Visits - Based upon individual need, an appointment with an occupational, physical, or speech therapist can be arranged. Through education and training, these therapists can help to foster independence, self-esteem, and better quality of life for the person living with MS.
  • Respite Care - Respite allows primary caregivers the opportunity to tend to themselves, or other family business, with the assurance that their loved one is being cared for by a properly trained individual. This service is provided on a short-term basis for a scheduled period of time. 
  • Coming Home - Returning home from a stay at the hospital can be a difficult time of transition. We offer a four-hour visit from an aide who will meet the patient at the hospital, provide transportation home, and then get the patient settled comfortably at home.
Health Care Access & Delivery Physical Therapy Caregiver Support / Respite Care +1 more

Multiple Sclerosis Foundation: Healthcare Assistance Grant

Multiple Sclerosis Foundation Inc
Private
United States
Unspecified amount

Healthcare Assistance Grant

The MS Focus Healthcare Assistance Grant assists uninsured individuals with the cost of visiting their MS specialist as well as dental assistance. The grant, which can pay for one visit and one follow-up, is designed to assist those already diagnosed with MS who may need a visit to their treating physician to renew a prescription or handle other important needs. 

Applicants give MS Focus staff authorization to negotiate costs directly with the provider, and the fee is paid directly to the doctor. 

Dental Health Health Care Access & Delivery Multiple Sclerosis

Tradition of Excellence Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Tradition of Excellence Scholarship

Benefiting dependents of current Perry Homes employees.

Education - Higher Education Career / College Preparation

ASPCA Right Horse Grants to Amplify Adoptions and Support Community Equines

American Society for the Prevention of Cruelty to Animals (ASPCA)
Private
United States
US $5,000 - US $50,000
The ASPCA Right Horse Grants aim to enhance equine adoptions and support community equines by funding programs that boost shelter capacity or assist in keeping owned equines in their homes. Grants between $5,000 and $50,000 are available, with a total funding pool of up to $750,000. Eligible applicants include ASPCA Right Horse Adoption Partners and organizations committed to the welfare of retired Thoroughbred racehorses. Proposals should clearly outline the objectives and expected impacts.
Animal Welfare - General Animal Welfare - Domestic Animals & Pets

Driving University Impact: Expanding the Public Exchange Network Grant

Social Science Research Council
Private
United States
US $300,000

Driving University Impact: Expanding the Public Exchange Network Grant

How the Public Exchange Network Works

No single university – even a large R1 – has enough faculty expertise available to meet the needs of every partner. The Public Exchange Network was designed to help universities work together seamlessly to build robust partnerships and generate more collective impact. Universities joining the network are independent but affiliated members, with full control over their own program and project portfolios. As a national network with local, on-the-ground capacity, Public Exchange Network members can also share approaches that work, scale solutions to common problems, and build cross-regional partnerships together. 

As an institutional partner in the Public Exchange Network, universities will build capacity to develop, test and implement solutions to the most urgent problems in their regions and beyond. Universities joining the Public Exchange Network get:

  • The tools, templates and training they need to start right away;
  • A shared brand they can plug into on day one;
  • A network of faculty, past and potential partners and philanthropic relationships, benefitting everyone in the network. 

Public Exchange Network Expansion grants will cover 75-80% of the minimum estimated annual costs for two years to launch a new Public Exchange. To launch a Public Exchange, universities must have the following in place: (1) a staff executive director with experience launching and leading social impact partnerships, (2) a project seed fund, and (3) a modest operations budget. We also recommend some in-kind project management support from an existing university staff member. The grant includes a two-year Public Exchange Executive Director (ED) compensation subsidy of $300,000 to launch the Public Exchange on campus, and a 2-year license to use the Public Exchange brand. New Public Exchange Network members will also receive ongoing support and guidance from current Public Exchange leadership and staff at USC and WashU, including recruitment support and intensive training for hiring and onboarding an executive director, a sub-site on the Public Exchange website, incubation and project management support from current Public Exchange staff, and a suite of tools for developing and implementing Public Exchange projects.

Humanities & Social Science Homelessness Services Disaster Relief / Humanitarian Aid +1 more

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.
Epidemiology & Public Health Patient Care & Services Biomedical Imaging +1 more

Powered & Prepared Initiative Grant

Hillman Family Foundations
Private
U.S. Territories, United States
US $300,000

About Henry L. Hillman Foundation

Henry L. Hillman Foundation inspires, invests in, and leverages great ideas to improve the quality of life in Pittsburgh and southwestern Pennsylvania.

Backup Power When Your Community Needs It

The Powered & Prepared Initiative seeks proposals from nonprofit and municipal organizations in southwestern Pennsylvania for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Southwestern Pennsylvania is increasingly impacted by severe weather events that cause widespread power outages and disruptions. The Powered & Prepared Initiative, supported by Henry L. Hillman Foundation, seeks proposals from nonprofit and municipal organizations for backup power solutions that allow those organizations to offer essential services during emergencies without disruption.

Basic Human Needs Emergency Medical Care & Services Disaster Relief / Humanitarian Aid +2 more

Building the Future Workforce Challenge Grant

Caterpillar
Corporate
Brazil, India +2 more
US $1,000,000

Building the Future Workforce Challenge

Awarding $5 million and the opportunity to test bold, tech‑forward solutions that strengthen the advanced manufacturing and industry technician workforce—today and for the future.

About the Challenge

Caterpillar knows preparing the workforce for the future is urgent. Communities, employers, and industry need new ways to close advancing skill gaps. The Building the Future Workforce Challenge invites fresh perspectives from all sectors to rethink training. Up to five teams will be awarded $1 million each for sustainable, tech‑forward solutions that strengthen today’s—and tomorrow’s—advanced manufacturing and industry technician talent pipelines.

What types of solutions are you looking for?

The Building the Future Workforce Challenge aims to identify, test, and scale innovative, sustainable solutions that will address today’s and tomorrow’s advanced manufacturing and industry technician skill gaps. A core requirement of any solution is that it remains relevant amid evolving technology—ensuring that breakthrough innovation and human potential rise together.

Strong proposals for Building the Future Workforce Challenge will meet four criteria outlined in the scoring rubric, and proposed solutions must focus on one or more of the following solution categories for Building the Future Workforce Challenge:

Workforce Preparation & Job Readiness Vocational & Trade Education Manufacturing Engineering +2 more

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders (2026-06-26)

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

Hematological Systems

Pediatric Hidradenitis Suppurativa Challenge Grant

Pediatric Dermatology Research Alliance Inc
Private
United States
Up to US $50,000

Pediatric Hidradenitis Suppurativa Challenge Grant

Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.

To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.

Focus

Proposals should address one or more of the following high-priority research topics:

  • Predicting treatment effectiveness and risk utilizing real world evidence and/or experience
  • Early disease and factors involved in severe disease development
  • Optimizing surgical and procedural approaches to minimize pain, shorten healing time, and reduce recurrence
  • Improving recruitment of diverse and representative populations for clinical studies, trials and advanced therapeutics

Funding:

  • Up to $50,000 to support one year of research
  • One award anticipated for this funding cycle
Children’s Health & Pediatrics

The Alpha Omega Alpha/Pharos Poetry Award

Alpha Omega Alpha Honor Medical Society
Private
United States
US $1,500

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.

Poetry Education - Higher Education

Summer Medical Internship Program (SMIP)

The Society of Interventional Radiology Foundation
Association/Society
United States
Up to US $6,000

Summer Medical Internship Program (SMIP)

Fosters an interest in research by funding a summer research project conducted by a medical student.

The SIR Foundation Summer Medical Internship Program introduces medical students to interventional radiology research and medical device development. The goal of this program is to foster an interest in research by funding a summer research project conducted by a medical student.

Students applying for the program must show strong potential for a career in IR with proven academic success. Selected students will have an opportunity to intern with an interventional radiologist research mentor or corporate research and development mentor for 8 weeks during the summer.

SIR Foundation will provide a $6,000 stipend to help ease the financial burdens throughout their internship experience.

  • Budget: Up to $6,000
  • Grant Length: Eight weeks
Apprenticeship & Internship Programs Medical Education & Professional Training

Hilcorp Future Leaders of America Scholarship

Greater Houston Community Foundation
Private
United States
Up to US $10,000

Hilcorp Future Leaders of America Scholarship

Benefiting select communities across the United States where Hilcorp operates.

The Hilcorp Future Leaders of America Scholarship Program was developed to give back to the communities in which Hilcorp Energy Company operates to develop future leadership talent as the next innovators, educators, and business leaders.

Award Amount

Multiple scholarships awarded annually. The scholarship is comprised of up to four (4) annual awards of $2,500, for a total award of up to $10,000.

The four annual (4) awards may be received over a period of up to 6 years, allowing for deferment if needed.

Education - Higher Education Career / College Preparation

GBA1 Parkinson's Disease Research Catalyst Program

Michael J Fox Foundation For Parkinsons Research
Private
Canada, United Kingdom +1 more
Up to US $300,000

GBA1 Parkinson's Disease Research Catalyst Program

The GBA1-PD Research Catalyst Program seeks to build a deeper, globally integrated understanding of GBA1-associated Parkinson’s disease by aligning efforts across geographies and maximizing the value of shared datasets and research assets. Funding will support hypothesis- driven projects with an emphasis on integrative, cross-cohort analyses and the systematic characterization and standardization of models to enable broad use by the research community.

Funding

Duration: 12 to 24 months

Award Amount: Up to $300,000. Requested support should be commensurate with work proposed.

These budgets include direct and indirect costs. For academic and for-profit institutions, no more than 15% or 10%, respectively, may go to indirect costs. 

Parkinson’s Disease

Patrick J. Kiley / Houston AGC Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

Patrick J. Kiley / Houston AGC Scholarship

Benefiting employees, dependents of employees, and/or interns of AGC Houston member firms OR students involved in AGC Student Chapters.

Award Amounts

Multiple awards are given each year. Scholarship award amounts will vary for each selected scholarship recipient.

Vocational & Trade Education

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Pfizer, Inc.
Corporate
United States
Up to US $100,000

Investigating the Benefit of Early Treatment with Ritlecitinib in Alopecia Areata: A Real-World Evidence Approach

Alopecia Areata (AA) is a chronic, immune-mediated condition causing nonscarring hair loss that affects about 2% of the global population and can lead to substantial psychosocial burden if disease is severe and untreated. The treatment landscape has recently evolved with the approval of ritlecitinib, a systemic therapy for severe AA in adults and adolescents aged 12 years and older, based on efficacy demonstrated in the ALLEGRO phase 2b/3 program.

Despite this advance, important questions remain regarding the optimal timing of therapy initiation. Emerging post-hoc analyses from the ALLEGRO program indicate that patients with shorter disease duration and lower baseline severity achieve higher response rates, suggesting that earlier intervention with ritlecitinib may lead to improved outcomes.

Geographic Scope

United States 

Funding Range and Project Length

Individual projects requesting up to $100,000 USD will be considered.

Maximum project length is 24 months.

Skin Diseases & Dermatology

Hemophilia Fellowship

Pfizer, Inc.
Corporate
United States
Up to US $100,000

Hemophilia Fellowship

This competitive grant program seeks to support an institution-based fellowship that emphasizes shared decision making (SDM), patient education, and multidisciplinary team-based care. The intent is to strengthen the hemophilia care through equitable education, and patient-centered shared decision making in a rapidly evolving treatment landscape.

Geographic Scope

  • United States 

Funding Range and Project Length

  • Grant funding is available to support a one year fellowship up to $100.000 USD. 
Hematological Systems

Accelerating the Development of Combined CGM–Pump Devices

Breakthrough T1D ( Formally JDRF International)
Private
United States
Up to US $900,000

Accelerating the Development of Combined CGM–Pump Devices

A combined continuous glucose monitor (CGM) and insulin pump device represents an innovative approach to simplifying diabetes management by integrating two essential technologies into a single device. This approach has the potential to improve quality of life for people with type 1 diabetes (T1D) by reducing the burden associated with wearing and managing multiple devices.

Despite this promise, the development of combined CGM–pump devices presents technical and commercialization challenges. These include the need for further advances in device compatibility and lifespan, system reliability, and scalable manufacturing, while maintaining affordability and broadaccessibility. In addition, a potential insulin dilution effect may require adjustment of the CGM algorithm.

Breakthrough T1D invites applications for research and development projects that address key technical, clinical, and translational challenges related to combined CGM–pump devices, with the goal of accelerating their development and improving outcomes for people living with T1D.

In response to this announcement, applications may request up to a total of $900,000 USD for up to three years. 

Diabetes

OREF/Musculoskeletal Transplant Foundation Research Grant

Orthopaedic Research and Education Foundation
Private
United States
US $100,000

OREF/Musculoskeletal Transplant Foundation Research Grant

Solicits investigator-initiated proposals focusing on research in the science of biologic – reconstruction, bone regeneration, transplantation - allografts, and including stem cells for graft transplantation.

Orthopedics

NEA Arts and Artifacts International Indemnity Program 1, FY2027 (9/26)

National Endowment for the Arts
Federal Government
American Samoa, Guam +4 more
US $1,000 - US $100,000
The NEA Arts and Artifacts International Indemnity Program, administered by the National Endowment for the Arts, provides financial protection for museums exhibiting significant art and artifacts. Launched in 1975, it minimizes insurance costs for international exhibitions. The program allows U.S. entities to receive indemnity for works of art while on display in the U.S. Applications are assessed by expert panels, ensuring a thorough review process before approvals or conditional notices are issued.
Art & Culture Arts / Culture Access & Participation

Davis B. and Barbara J. Francis Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Davis B. and Barbara J. Francis Scholarship Fund, established by the Community Foundation Serving Western Virginia, provides educational scholarships to deserving students in the Roanoke Valley. It aims to support graduating seniors or former graduates pursuing careers in technical theatre or performing arts. Applicants must demonstrate significant contributions to their school's theatre arts program and enroll in an accredited college or technical school. Financial need is considered but not the primary criterion.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Clarence Lee Lester Educational Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Clarence Lee Lester Educational Fund, administered by the Community Foundation Serving Western Virginia, provides scholarships to deserving students pursuing higher education. Eligible applicants must be graduating seniors with a minimum 2.5 GPA and a connection to First Baptist Church in Martinsville, VA. This scholarship aims to support capable individuals in their academic journeys, ensuring that financial barriers do not hinder their educational aspirations. For more information, contact the Foundation directly.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Carolyn and Bill Franck Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Carolyn and Bill Franck Scholarship Fund, managed by the Community Foundation Serving Western Virginia, provides essential financial support for graduating high school seniors from Henry County or Martinsville pursuing post-secondary education in various fields. Eligible applicants must maintain a GPA of at least 2.5 and demonstrate financial need through the FAFSA. This scholarship aims to empower deserving students by facilitating their educational aspirations in accredited institutions.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Bratcher Family Foundation Scholarship

Greater Houston Community Foundation
Private
United States
US $4,000 - US $6,000

Welcome to the Greater Houston Community Foundation Scholarship Application Site!   

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Scholarship Application Info:  

Greater Houston Community Foundation administers over 60 different scholarship programs, each with differing eligibility requirements. Eligibility for some scholarships may be dependent on employment, course of study, high school, or college. 

Bratcher Family Foundation Scholarship

This is a renewable scholarship, meaning recipients can renew the award for multiple years funding if they meet the GPA and enrollment requirements and complete the renewal application for each academic year they plan to be enrolled.

About the Scholarship Award

  • One (1) new scholarship awarded annually. Scholarship award amounts and renewal durations vary by degree type:
    • 4-year degree at a college/university - $6,000 per academic year
      • Renewable for up to four (4) years of funding maximum ($24,000 in total), as long as the student meets renewal requirements
  • 2-year degree at a trade school/community college - $4,000 per academic year
    • Renewable for up to two (2) years of funding maximum ($8,000 in total), as long as the student meets renewal requirements

What can the scholarship be used for?

  • The scholarship will be mailed directly to the student's college to be used towards tuition, required academic fees, and/or book expenses. 
  • Scholarship funding cannot be distributed directly to the student. Funding cannot be used for room and board, rent, meal plans, parking passes, or other similar living expenses.

Are there any requirements I must meet if I'm selected as a scholarship recipient?

  • Recipients must attend an accredited university, community college, or trade school in the United States.
  • Recipients must enroll in at least 12 credit hours for both the fall and spring semesters (or be enrolled full-time according to your school if it is on a different system).
  • Recipients must submit college enrollment information online through GHCF Scholar the summer before the academic year begins. This information is required in order for the scholarship check to be mailed to the student's college. Instructions will be included in the student's award letter.
  • Recipients must meet certain criteria in order to receive subsequent annual awards (i.e., renewals): maintain a minimum cumulative GPA of 2.75, be enrolled in at least 12 credit hours per semester, and complete the renewal application for each academic year they planned to be enrolled.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Bright Minds Scholarship

Salem Five Charitable Foundation
Corporate
United States
Up to US $20,000

Bright Minds Scholarship

The Bright Minds Scholarship, in conjunction with the Salem Five Charitable Foundation, supports academic excellence and community leadership across Essex and Middlesex counties. We recognize that the journey to a four-year degree requires significant dedication—and significant resources.

To support that journey, we provide a scholarship award designed to make a real-world impact on the cost of higher education.

The Award

  • 5 Scholars Selected Annually: Each year, we name five exceptional students as Bright Minds Scholars.
  • Up to $20,000 total: Awarded as $5,000 annually over four years of undergraduate study.
  • Maintain good academic standing to receive support throughout your entire bachelor's degree program.

The Salem Five Charitable Foundation is a 501(c)(3) organization. Scholarship awards are granted without regard to race, color, religion, sex, national origin, or disability. Final selection of scholarship recipients is at the sole discretion of the Salem Five Executive Committee in partnership with the Phillips Scholarship Fund.

Education - Higher Education Career / College Preparation

South Dakota Grants for Nonprofits Highlights

South Dakota grants for nonprofits provide funding to support rural development, education, public health, and cultural preservation initiatives. The following grants help organizations address community challenges, foster sustainability, and enhance quality of life across South Dakota.


Search Instrumentl's South Dakota Grants Database


Find 106 funding opportunities for nonprofits in South Dakota, with $6.4M available. Instrumentl streamlines the funding process by offering grant-matching tools, deadline alerts, and key insights to help organizations achieve their missions.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : South Dakota Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ South Dakota grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 South Dakota grants for nonprofits over $25K in average grant size

23 South Dakota grants for nonprofits over $50K in average grant size

23 South Dakota grants for nonprofits supporting general operating expenses

91 South Dakota grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for South Dakota grants for Nonprofits?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for South Dakota Grants for Nonprofits?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Frequently asked questions

A wide variety of funding sources for nonprofits are available in South Dakota. Currently, 100+ are available, totaling $6,365,150. For organizations interested in pursuing grant funding in South Dakota, the median grant size is $10,000. Among these grants, 23 grants support general operating expenses while 91 grants fund projects and programs specifically.

Various organizations and institutions provide grants for the state of South Dakota, including government agencies, private foundations, associations, and more. Here’s a breakdown of where you'll find the most grants available:

  • State & Local Government: The state of South Dakota offers over 29 grants. Many of these funding opportunities focus on agriculture.
  • Private Foundations: Around 43 private foundation grants are available in the state of South Dakota, with focus areas ranging from rural development to health and medicine.
  • Corporate Funders: There are around 17 open corporate grants. These grants mainly focus on agriculture and human and social services.

Whether you go after government grants or foundation grants depends on your grant readiness. Keep in mind that government grants often have large awards but equally large compliance requirements.

Based on the data we have now, the best time to apply for grants in South Dakota is in Q1, which is when about 34.7% of grant deadlines fall. This period offers nonprofits the most opportunities to secure funding. Comparatively, Q3 has the least activity, with only 19.8% of deadlines. To maximize your chances of securing funding, be aware of the peak fundraising periods.

The nonprofit funding landscape throughout South Dakota has shown significant activity over the past several years. Based on the funding reports sent to the IRS, overall grant funding reached $481,503,794 in 2021 and then rose to $619,327,674 in 2022, an increase of about 28.62%. Among all the grants awarded in South Dakota, the most popular focus areas for funding were single-organization support from private grantmaking, single-organization support, professional societies, associations and research institutes, and/or public policy analysis. Likewise, the top counties that received the most funding were Pennington County, Minnehaha County and Todd County.

If you want to start finding more grants, Instrumentl simplifies the entire grant process. You can find grants within South Dakota for your nonprofit while also researching funders, managing deadlines, and keeping on top of everything in our all-in-one platform.

With Instrumentl, you'll get access to over 20,000 live grants and 400,000 funders beyond what you see here in South Dakota. Learn more about Instrumentl’s powerful grant platform.

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