Upcoming Webinar
Instrumentl Fall Launch: Your Grant Operating System Has Leveled Up.
Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best South Dakota Grants for Nonprofits

Find nonprofit grants in South Dakota, including opportunities in Sioux Falls, Rapid City, and Aberdeen. Updated listings for 501(c)(3) organizations statewide.

9,000+

Available grants

$3.26B

Total funding

$5K

Median grant

9,000+ grants
$3.26B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,106 Results based on applied filters

Brothers Helping Brothers: Backing Safety Initiative Grants

Brothers Helping Brothers
Private
United States
Unspecified amount in in-kind support
The Brothers Helping Brothers initiative aims to provide essential equipment to small fire departments and EMS organizations in the U.S. Established in 2014, the program offers grants to eligible agencies serving communities with populations under 10,000. With a focus on tools like wireless backup cameras, the organization strives to enhance safety and operational efficiency for first responders. Through community support, they have raised significant funds to assist in this critical mission.
Firefighting & Fire Prevention Emergency Medical Care & Services

National Community Care Corps Grant

US HHS: Administration for Community Living (ACL)
Federal Government
United States
US $30,000 - US $200,000

National Community Care Corps Grant

Community Care Corps encourages organizations across the country to apply for 18-month grants ($30,000–$200,000) to develop and scale innovative volunteer programs that provide nonmedical assistance to older adults, adults age 18 and older with disabilities and family caregivers.

Projects funded through this initiative will increase the number of community-based volunteer programs available to provide nonmedical assistance while decreasing the number of older adults, adults with disabilities, and family caregivers who need assistance in maintaining independence in the community but are unable to obtain help. In doing so, the initiative will strengthen community-based supports that help people maintain independence, reduce unmet needs, and improve overall well-being.

Focus Areas

Proposals must include one or more of the following focus areas:

  • Integrate principles of the National Strategy to Support Family Caregivers
  • Support grandparent/kinship-led households
  • Use off-the-shelf materials. Off-the-shelf materials are products, components, or resources that are readily available for purchase and immediate use, without the need for custom development, modification, or special ordering
  • Engage college students/interns for intergenerational connections
  • Expand virtual or low-tech access
  • Provide volunteer chaperone programs for non-emergency medical appointments
  • Increase access to respite programs
  • Build opportunities for volunteer skill-building
Caregiver Support / Respite Care Senior Services Volunteerism & Philanthropy

Dale Jr. Foundation Donations

Dale Jr Foundation
Private
United States
Up to US $5,000
The Dale Jr. Foundation, founded by NASCAR driver Dale Earnhardt Jr., has raised over $8 million since 2007 to support various charities focusing on youth and underprivileged communities. The foundation emphasizes empowerment, education, wellness, hunger relief, and hope, aiming to provide resources that enhance confidence and opportunities for children facing hardships. Through fundraising efforts and partnerships with organizations like Make-A-Wish, the foundation strives to positively impact lives and foster a sense of normalcy among children in need.
Youth Development & Leadership Youth Services Educational Access & Equity +7 more

Disability Inclusion Fund Grant

Borealis Philanthropy
Private
American Samoa, Guam +4 more
US $75,000 - US $150,000
The Disability Inclusion Fund Grant, managed by Borealis Philanthropy, aims to support organizations advocating for disability inclusion, rights, and justice. As a partner in philanthropy, Borealis facilitates donor collaboratives to maximize impact across various communities and movements. Organizations interested in applying for this grant are encouraged to review the detailed FAQ for further information. This initiative is a vital step towards fostering inclusivity and promoting the rights of individuals with disabilities.
Disability Care & Services Disability Rights & Justice Diversity, Equity & Inclusion

Cameron Award: Guy N. Cameron Rodent Research Award

American Society of Mammalogists
Association/Society
Central America, North America +1 more
US $5,000
The Cameron Award supports field research on native rodents across the Americas, encouraging studies in ecology, behavior, physiology, and conservation. It is available to students in MS or PhD programs and postdoctoral researchers in the U.S. Applicants must be ASM members. Funds cover supplies, equipment, and travel, but not salaries or meeting travel. The award aims to enhance understanding of rodent ecology and their impact on ecosystems.
Mammalogy Mammalian Conservation

Republic Services: Community Grant Program

Republic Services Charitable Foundation
Corporate
Puerto Rico, United States
Unspecified amount
The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.
Disaster Relief / Humanitarian Aid Community / Public Safety Human & Social Services

Bausch Foundation Contributions

Bausch & Lomb Foundation Inc
Private
United States
Unspecified amount
The Bausch Foundation, established by Bausch Health Companies Inc., supports global charitable initiatives focused on disease prevention, improving patient outcomes, and education related to its core businesses. The Foundation also aids disaster recovery efforts and assists underserved communities. Applications for funding are accepted continuously, with quarterly reviews, ensuring timely support for impactful projects. All submissions must be unsolicited, and decisions by the Advisory Committee are final, fostering a transparent giving process.
Preventative Healthcare Disaster Relief / Humanitarian Aid Patient Care & Services

Gender Justice Organizing Fund Grant

Bread & Roses Community Fund
Private
United States
US $10,000
The Gender Justice Organizing Fund Grant supports initiatives led by women, girls, trans, gender nonconforming, and LGBTQI+ individuals to achieve gender justice. Organizations must prioritize community organizing and demonstrate an understanding of systemic oppression. Grants from the Bread & Roses Community Fund are crucial for groups that lack traditional funding due to their commitment to amplifying marginalized voices. The fund emphasizes long-term strategies that foster sustainable social change in the Philadelphia area.
Women's Rights & Equality Sexuality & LGBTQIA+ Rights

Youth Programming Grant

Native American Agriculture Fund
Private
United States, United States Minor Outlying Islands
Unspecified amount
The Youth Programming Grant, offered by the Native American Agriculture Fund (NAAF), aims to support Native American farmers and ranchers through various projects. This grant focuses on providing essential business assistance, agricultural education, and advocacy services. By funding diverse initiatives, the NAAF seeks to promote the ongoing involvement of Native communities in agriculture, ensuring their sustainable growth and development within the sector.
Agricultural Education

Emerging Leader Award

The Mark Foundation for Cancer Research
Private
Canada, United States
US $1,000,000
The Mark Foundation Emerging Leader Award supports innovative cancer research led by early career investigators. Aimed at high-impact, high-risk projects, this grant is available to those employed by U.S. or Canadian non-profit academic institutions. Eligible applicants must be within three to eight years of starting their independent faculty research appointment. This award emphasizes multi-year independent funding and is not intended as the main funding source for the laboratory, ensuring that diverse research efforts are encouraged.
Cancer / Oncology

Disability Foundation Grants

The Dayton Foundation
Private
United States
Up to US $10,000
The Disability Foundation, in partnership with The Dayton Foundation, invites proposals for grants aimed at supporting organizations providing direct services to individuals with disabilities. Eligible applicants include community-based nonprofits and academic institutions. Grants, capped at $10,000, can be used for various purposes such as enhancing service accessibility, purchasing necessary equipment, and expanding services. This initiative seeks to empower disabled individuals by ensuring they receive essential resources and support.
Disability Care & Services Disaster Relief / Humanitarian Aid

NIHCM: Research Grants

The National Institute for Health Care Management
Private
United States
US $50,000 - US $60,000
The NIHCM Foundation is seeking innovative research proposals that address critical issues in U.S. health care, particularly focusing on drug pricing, provider consolidation, health care delivery, chronic disease management, and the role of artificial intelligence. Projects should aim to improve affordability and quality of care. We welcome submissions from a variety of researchers and organizations, with a preference for studies that can be completed within one year.
Health Policy & Advocacy Health Care Access & Delivery Health Disparities & Social Determinants of Health +4 more

NIHCM: Journalism Grants

The National Institute for Health Care Management
Private
United States
Unspecified amount
The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.
Journalism Health Information Technology Health Policy & Advocacy +5 more

SFP: Changemakers in Family Planning Grant Program

Society Of Family Planning Research Fund
Private
American Samoa, Guam +4 more
Unspecified amount
The Changemakers in Family Planning Grant Program aims to address institutionalized racism in the field of family planning by providing essential support to scholars of color. Recognizing that diversity and equity are crucial for advancing research in abortion and contraception, this initiative seeks to foster an inclusive community that empowers underrepresented voices in science. The Society of Family Planning is dedicated to creating a just environment where all scholars can contribute to meaningful advancements in family planning research.
Reproductive Health Reproductive Rights Reproductive Education

SFP: Emerging Scholars in Family Planning Grant

Society Of Family Planning Research Fund
Private
United States
Up to US $7,500
The Emerging Scholars in Family Planning Grant, offered by the Society of Family Planning, aims to support early-career researchers in developing a family planning research portfolio. This grant provides funding for publishable scholarly research projects, including thesis or dissertation work, fostering the next generation of scholars in abortion and contraception research. By promoting diversity and inclusion, the grant seeks to build a multidisciplinary community dedicated to advancing family planning science.
Reproductive Education Reproductive Health Reproductive Rights

Robert and Joan Dircks Foundation Grant Program

Robert & Joan Dircks Foundation
Private
United States
US $1,000 - US $15,000
The Robert and Joan Dircks Foundation Grant Program supports non-profit organizations in New Jersey that provide opportunities for disadvantaged individuals. With grants ranging from $1,000 to $15,000, the foundation focuses on innovative programs that solve critical issues rather than operational needs. Eligible organizations must be tax-exempt under section 501(c)(3) of the Internal Revenue Code. The foundation does not fund political activities, cultural projects, or operating budgets, ensuring resources directly benefit those in need.
Children With Disabilities Poverty Alleviation & Services Disability Care & Services +3 more

Sustainable Slopes Grants

National Ski Areas Association
Private
United States
Unspecified amount
The Sustainable Slopes Grant Program, initiated by the National Ski Areas Association in 2009, supports NSAA member ski areas in their sustainability efforts. With over $890,000 awarded, the program facilitates projects that enhance energy efficiency, protect natural habitats, and promote recycling. This year, applicants can apply for Cash Grants, the Herman K. Dupré Sustainable Snowmaking Grant, or the new Recycling Grant, all aimed at reducing environmental footprints and achieving sustainability goals.
Outdoor Recreation Sustainability Snow Sports

St. Baldrick's Foundation: Infrastructure Awards

St Baldricks Foundation Inc
Private
United States
US $25,000 - US $50,000
The St. Baldrick's Foundation offers Infrastructure Awards to support institutions in enhancing their capacity for childhood cancer clinical trials. These grants are aimed at smaller entities lacking necessary resources, enabling them to hire personnel and acquire vital tools to increase participation. Since 2005, the Foundation has invested over $356 million in childhood cancer research, focusing on collaboration and innovation to find cures. Institutions in the U.S. are eligible, promoting broader access to crucial clinical trials.
Pediatric Cancers

Educational Outreach Program for General Psychiatry Residents Grant Program

American Academy of Child & Adolescent Psychiatry
Private
United States
Up to US $1,200
The AACAP Educational Outreach Program for General Psychiatry Residents offers a unique opportunity for residents to gain insights into child and adolescent psychiatry. Participants will network with mentors and peers, attend the 71st AACAP Annual Meeting from October 14-19, 2024, and receive a stipend of up to $1,200 post-meeting. This program prioritizes first-time applicants, ensuring a valuable experience in a supportive environment while expanding professional connections.
Mental Health & Psychiatric Diseases

The Skatepark Project Grants

Tony Hawk Foundation
Private
United States
US $1,000 - US $25,000
The Skatepark Project Grants aim to support underserved communities in building public, free, concrete skateparks for youth. Eligible applicants include public charities and local agencies committed to designing inclusive spaces. The projects must engage local skaters in planning and fundraising, promote safety, and be open year-round without entry fees. The initiative fosters community involvement and addresses social inequalities, ensuring that all types of skatepark users can benefit from these vital recreational resources.
Parks & Public Spaces Youth Services

Grey Muzzle Grants

Grey Muzzle Organization
Private
United States
Unspecified amount
The Grey Muzzle Organization offers grants ranging from $2,500 to $10,000 to improve the lives of at-risk senior dogs across the U.S. Since 2008, they have awarded over $2.5 million to shelters and nonprofits focused on senior dog welfare. Eligible applicants must be 501(c)(3) organizations and demonstrate measurable outcomes. The initiative aims to ensure that every senior dog thrives, providing support for foster care, hospice services, and adoption programs.
Veterinary Science & Services Animal Welfare - Domestic Animals & Pets

The Father's Table Foundation Grant

The Father's Table Foundation
Private
United States
Up to US $750,000
The Father's Table Foundation Grant aims to glorify God by addressing the immediate and future needs of women and children globally. This selective grant process emphasizes building self-sufficiency and resilience among beneficiaries, focusing on proven partners capable of expanding their impact. The foundation supports a diverse range of projects, including employment assistance, education, humanitarian aid, and health care, ensuring that aid not only meets urgent needs but also fosters long-term sustainability.
Catholicism Children’s Health & Pediatrics Children’s Mental Health +17 more

Mutual of America's Community Partnership Award

Mutual Of America Foundation
Corporate
United States
Unspecified amount
The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.
All fields of work

Takeda Oncology Donation, Grant, and Sponsorship Opportunities

Takeda
Corporate
United States
Unspecified amount
Takeda Oncology offers grant funding opportunities aimed at addressing unmet educational and research needs in the medical community. They prioritize support for programs in hematology, thoracic, and gastrointestinal cancers, including lymphoma, leukemia, and previously treated metastatic colorectal cancer. Takeda encourages partnerships that enhance patient outcomes and provide tangible benefits through donations, grants, and sponsorships. Applications must be submitted at least 60 days prior to the program start date for timely review.
Medical Education & Professional Training

Overwatch Alliance Grants

Overwatch Alliance
Private
United States
Up to US $15,000
The Overwatch Alliance Grants support non-profit organizations with annual revenues of $500,000 or less that aid military members, veterans, and their families. Grants of up to $15,000 are available for impactful projects such as emergency financial assistance, transitional housing, and employment support. Eligible organizations must be IRS-designated 501(c)(3) entities. The Alliance encourages applications from those addressing crucial veteran community needs while reinforcing the importance of community backing for capital projects.
Military & Veterans Services

Myelodysplastic Syndromes (MDS) Research Fund Grant

Vera and Joseph Dresner Foundation
Private
United States
Up to US $500,000
The Myelodysplastic Syndromes (MDS) Research Fund Grant, established by the Vera and Joseph Dresner Foundation, aims to enhance research and treatment of MDS and related blood disorders. This fund supports innovative projects addressing etiology, biology, genetics, prognosis, treatment, symptom management, and quality of life. It offers up to $125,000 for Early Career Awards and $250,000 for Established Investigator Awards, facilitating significant advancements in the field.
Cancer / Oncology

SC Ministry Foundation: Annual Grants

SC Ministry Foundation
Private
United States
Unspecified amount
The SC Ministry Foundation provides annual grants aimed at supporting nonprofit organizations aligned with the mission of the Sisters of Charity of Cincinnati. These grants can be used for core programs, planning, and program expansion. Eligible organizations must demonstrate financial sustainability and avoid duplication of services. The application process starts with a pre-application survey, and funding decisions are typically made by June 30. Priority is given to projects in education, healthcare, and social services.
Social Justice / Human Rights Education Health Care Access & Delivery +2 more

South Dakota Grants for Nonprofits Highlights

South Dakota grants for nonprofits provide funding to support rural development, education, public health, and cultural preservation initiatives. The following grants help organizations address community challenges, foster sustainability, and enhance quality of life across South Dakota.


Search Instrumentl's South Dakota Grants Database


Find 105 funding opportunities for nonprofits in South Dakota, with $11.8M available. Instrumentl streamlines the funding process by offering grant-matching tools, deadline alerts, and key insights to help organizations achieve their missions.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : South Dakota Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ South Dakota grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

32 South Dakota grants for nonprofits over $25K in average grant size

25 South Dakota grants for nonprofits over $50K in average grant size

21 South Dakota grants for nonprofits supporting general operating expenses

92 South Dakota grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

2,000+ Grants on Instrumentl focused on Community Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for South Dakota grants for Nonprofits?

Most grants are due in the first quarter.

Q1
35.5%
Q2
26.7%
Q3
18.3%
Q4
19.5%

Typical Funding Amounts

What's the typical grant amount funded for South Dakota Grants for Nonprofits?

Grants are most commonly $10,500.

$250 $250 Min.
$10,500 $10.5 K Median
$166,817 $166.8 K Average
$5,000,000 $5 M Max.

Frequently asked questions

A wide variety of funding sources for nonprofits are available in South Dakota. Currently, 100+ are available, totaling $11,843,991. For organizations interested in pursuing grant funding in South Dakota, the median grant size is $10,500. Among these grants, 21 grants support general operating expenses while 92 grants fund projects and programs specifically.

Various organizations and institutions provide grants for the state of South Dakota, including government agencies, private foundations, associations, and more. Here’s a breakdown of where you'll find the most grants available:

  • State & Local Government: The state of South Dakota offers over 29 grants. Many of these funding opportunities focus on agriculture.
  • Private Foundations: Around 40 private foundation grants are available in the state of South Dakota, with focus areas ranging from rural development to health and medicine.
  • Corporate Funders: There are around 18 open corporate grants. These grants mainly focus on agriculture and human and social services.

Whether you go after government grants or foundation grants depends on your grant readiness. Keep in mind that government grants often have large awards but equally large compliance requirements.

Based on the data we have now, the best time to apply for grants in South Dakota is in Q1, which is when about 35.5% of grant deadlines fall. This period offers nonprofits the most opportunities to secure funding. Comparatively, Q3 has the least activity, with only 18.3% of deadlines. To maximize your chances of securing funding, be aware of the peak fundraising periods.

The nonprofit funding landscape throughout South Dakota has shown significant activity over the past several years. Based on the funding reports sent to the IRS, overall grant funding reached $481,503,794 in 2021 and then rose to $619,327,674 in 2022, an increase of about 28.62%. Among all the grants awarded in South Dakota, the most popular focus areas for funding were single-organization support from private grantmaking, single-organization support, professional societies, associations and research institutes, and/or public policy analysis. Likewise, the top counties that received the most funding were Pennington County, Minnehaha County and Todd County.

If you want to start finding more grants, Instrumentl simplifies the entire grant process. You can find grants within South Dakota for your nonprofit while also researching funders, managing deadlines, and keeping on top of everything in our all-in-one platform.

With Instrumentl, you'll get access to over 20,000 live grants and 400,000 funders beyond what you see here in South Dakota. Learn more about Instrumentl’s powerful grant platform.

Browse South Dakota Grants by Focus Area

Filter South Dakota Grants by Location

Browse Grants by Counties within South Dakota

Browse Grants by Major US Cities within South Dakota

Explore Grants Outside of South Dakota

Browse Grants by Other States or Regions