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Best South Dakota Grants for Nonprofits

Find nonprofit grants in South Dakota, including opportunities in Sioux Falls, Rapid City, and Aberdeen. Updated listings for 501(c)(3) organizations statewide.

9,000+

Available grants

$2.63B

Total funding

$5K

Median grant

9,000+ grants
$2.63B total
$5K median

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9,246 Results based on applied filters

Cardiovascular & Pulmonary Research Grants

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Cardiovascular & Pulmonary Research Grants aim to support impactful research that enhances cardiovascular and pulmonary health through physical therapy interventions. This grant emphasizes studies that assess patient characteristics, improve health outcomes, and address disparities. Research proposals must align with the 2023 APTA Research Agenda and prioritize clinical relevance, employing various investigative designs. The goal is to foster innovative approaches that significantly reduce cardiovascular disease risks and improve patient care in the U.S.
Cardiovascular Diseases & Systems Chronic Obstructive Pulmonary Disease Physical Therapy

Regional Public Interest Awards

Equal Justice Works
Private
United States
US $250
The Regional Public Interest Awards recognize eight outstanding law students annually for their dedication to public interest law. Selected by the Equal Justice Works National Advisory Committee, each recipient demonstrates exceptional commitment through volunteer work, internships, and clinics. Awardees receive a $250 cash prize and a commemorative plaque, celebrating their significant contributions to their communities and the legal profession.
Legal Services

Water and Waste Facility Loans and Grants to Alleviate Health Risks on Tribal Lands

USDA: Rural Development (RD)
Federal Government
United States
Unspecified amount
The Water and Waste Facility Loans and Grants program aims to provide safe drinking water and waste disposal services to low-income communities on Tribal lands, addressing significant health risks. Eligible applicants include federally-recognized Tribes, state and local governments, and nonprofit organizations. Funding can be used for constructing essential water and waste systems, and while matching funds are typically required, a full grant is possible under certain conditions. Applications are accepted year-round.
Sanitation & Clean Drinking Water Waste Management Water Resource Management +3 more

Water and Waste Facility Loans and Grants to Alleviate Health Risks for Colonias

USDA: Rural Development (RD)
Federal Government
United States
Unspecified amount
The USDA Rural Development program provides essential loans and grants to improve water and waste disposal services in low-income communities, specifically targeting Colonias recognized before 1989. This initiative aims to alleviate health risks associated with inadequate access to safe drinking water and waste management. Eligible applicants include federally-recognized tribes and local governments, with funds supporting the construction of vital infrastructure to ensure community health and sustainability.
Sanitation & Clean Drinking Water Epidemiology & Public Health Waste Management +3 more

SEARCH - Special Evaluation Assistance for Rural Communities and Households Grant

USDA: Rural Development (RD)
Federal Government
United States
Unspecified amount
The SEARCH Grant provides essential support for very small, financially distressed rural communities by funding predevelopment feasibility studies and technical assistance for water and waste disposal projects. Eligible applicants include state and local governments, nonprofits, and federally recognized tribes. Funds can be used for feasibility studies, design analysis, and technical help in securing financial assistance, ensuring improvements in rural infrastructure and community health.
Sanitation & Clean Drinking Water Waste Management Water Resource Management +2 more

Disaster Resilience Program Fellowship

Equal Justice Works
Private
United States
More than US $7,000
The Disaster Resilience Program Fellowship supports low-income communities affected by disasters by mobilizing lawyers and law students to provide free civil legal aid. This initiative ensures access to essential legal services, helping families navigate recovery barriers. Attorney Fellows receive a salary while Student Fellows earn a stipend for their service. Participants engage in outreach, build community relationships, and receive comprehensive training to enhance their legal skills, contributing to the resilience of affected communities.
Legal Services Disaster Relief / Humanitarian Aid

Design-Your-Own Fellowship

Equal Justice Works
Private
United States
Unspecified amount
The Design-Your-Own Fellowship by Equal Justice Works allows lawyers to create personalized projects addressing critical legal needs in underserved communities. Participants collaborate with preferred organizations to develop innovative solutions while receiving substantial financial support, health benefits, and professional training. This program not only enhances access to justice but also promotes diversity within public interest careers, empowering candidates to make meaningful impacts in their chosen fields.
Legal Services

CSA Grace D. Dreher Memorial Scholarship

Center for Scholarship Administration (CSA)
Private
United States
Unspecified amount
The CSA Grace D. Dreher Memorial Scholarship supports deserving students from Stroudsburg High School. Funded by the Grace D. Dreher Memorial Trust, it offers one-year scholarships for full-time college enrollment at accredited institutions in the U.S. Eligible applicants must demonstrate financial need and have a minimum GPA of 2.0 on a 4.0 scale. Current recipients may reapply, but awards are not guaranteed and depend on the applicant pool each year.
Career / College Preparation Academic Scholarship Programs

ETC: Equipment Grant

ETC
Corporate
United States
Unspecified amount
The ETC Equipment Grant supports U.S.-based non-profit organizations, schools, and government entities by providing essential lighting technology. This initiative, part of ETC's Light the Way Program, aims to enhance training in performance arts through equipment grants. Recipients can choose from a variety of packages, including consoles and LED fixtures, tailored to their facility's needs. ETC also offers training for all awarded equipment, ensuring recipients maximize the impact of their grants.
Performing Arts

Chapman Foundation Grant

Alvah H And Wyline P Chapman Foundation
Private
United States
Unspecified amount
The Alvah H. and Wyline P. Chapman Foundation offers grants to support charitable, educational, and community-focused initiatives, primarily in Florida and Georgia. Eligible applicants must be IRS-recognized 501(c)(3) organizations. The foundation prioritizes projects that address children's welfare, education, multicultural understanding, substance abuse prevention, and homelessness. Grants typically do not exceed $15,000, and proposals must be endorsed by a Foundation Director. Interested parties should submit a Letter of Inquiry for consideration.
Community Culture & Heritage Education Homelessness Services +10 more

Professional & Technical Training Scholarships- Sausalito Rotary Scholarship

10000 DEGREES
Private
United States
Up to US $1,500
The Professional & Technical Training Scholarships, offered by 10,000 Degrees, aim to support Marin County students facing financial challenges. These scholarships are designed for individuals enrolled in vocational programs that lead to a license or certificate. Eligibility includes being a Marin resident, attending an accredited institution, and having a GED or high school diploma. Preference is given to residents of Southern Marin, ensuring that local students receive the assistance they need to pursue their career goals.
Vocational & Trade Education Career / College Preparation

Dr. Ralph and Marian Falk Medical Research Trust – Falk Transformational Awards

Health Resources in Action
Private
United States
Up to US $1,000,000
The Dr. Ralph and Marian Falk Medical Research Trust offers the Falk Transformational Awards to provide critical bridge funding for successful Catalyst Award recipients. These awards, which can be up to $1M for a period of 2-3 years, aim to advance healthcare innovations, overcome scientific challenges, and promote new treatment avenues. Managed by Health Resources in Action, the program emphasizes improving medical treatments and finding cures for diseases that currently lack definitive solutions.
Diseases & Conditions Biomedical informatics

Community Betterment Committee Funding Grant

ETC
Corporate
United States
Up to US $5,000
ETC's Community Betterment Committee Funding Grant provides financial support to non-profit organizations across the United States. Established in 1975, ETC focuses on fostering community initiatives by awarding grants up to $5,000 semi-annually. The selection process is conducted by a committee of employee volunteers, ensuring that funds are allocated to a variety of deserving causes. This initiative reflects ETC's commitment to enhancing community welfare and supporting local initiatives.
Community Services

Joe and Janet Barr Early Career Cornea and Contact Lens Research Award

American Academy of Optometry Foundation Inc.
Corporate
United States
US $2,000
The Joe and Janet Barr Early Career Cornea and Contact Lens Research Award supports first- or second-year MS or PhD students in vision science or physiological optics. Established in 2012 in honor of Joseph T. Barr, this $2,000 seed funding facilitates research in cornea/ocular surface or contact lenses. Recipients are required to attend the annual American Academy of Optometry meeting and submit progress reports detailing their research outcomes. Preference is given to North American applicants.
Eye Diseases & Disorders

AJMMI: Rapid Response Grants

A.J. Muste Memorial Institute for Nonviolence and Social Justice
Private
United States
Up to US $5,000
The AJ Muste Foundation's Rapid Response Grants support U.S.-based organizations engaged in grassroots activism for social justice. These grants, up to $5,000, are aimed at addressing immediate needs of groups fighting for equality and liberation. The funding is designed for unexpected opportunities and emergencies, promoting powerful organizing efforts. The foundation prioritizes groups lacking traditional funding sources and those focused on systemic change rather than individual support.
Civic Engagement & Education Social Justice / Human Rights

Air Dominance Broad Agency Announcement (BAA)

US DOD: Dept. of the Air Force, Materiel Command
Federal Government
American Samoa, Guam +4 more
Up to US $750,000,000
The Air Dominance Broad Agency Announcement (BAA) invites proposals for research aimed at enhancing national security through scientific study and experimentation. Managed by the Air Force Research Laboratory, this unrestricted acquisition encourages small businesses to participate. Proposals must demonstrate substantive research results and comply with federal regulations, ensuring a competitive selection process. The BAA supports exploratory and advanced development programs, with a focus on practical applications and potential experimental testing.
Emerging Technology Development Domestic / Homeland Security Aerospace Engineering +1 more

Salt Lick Incubator- Artist Project Grant

Salt Lick Incubator Incorporated
Private
United States
US $5,000 - US $15,000
The Salt Lick Incubator offers project grants ranging from $5,000 to $15,000 for emerging musicians in contemporary genres. These grants support activities such as recording, music videos, and marketing strategies. Recipients receive mentorship to enhance their careers and participate in analytics tracking to refine their strategies. With a focus on song-driven music, the incubator also hosts retreats and performances, fostering collaboration and growth for artists at various stages of their careers.
Music Performing Arts

Brower Youth Awards for Environmental Leadership

Earth Island Institute Inc
Private
North America
US $3,000
The Brower Youth Awards for Environmental Leadership honors young leaders aged 13 to 22 in North America who excel in environmental initiatives. Awardees receive a $3,000 cash prize, training, and networking opportunities to enhance their impact. This prestigious program fosters youth leadership and amplifies diverse voices within the environmental movement, encouraging innovative solutions to pressing ecological challenges. Over the past 25 years, the awards have celebrated over 100 emerging leaders dedicated to making a difference in their communities.
Environmental Justice & Advocacy Environmental Stewardship Youth Development & Leadership +3 more

Black Voices Nomination

Black Voices For Black Justice Fund
Private
United States
US $20,000 - US $50,000
The Black Voices Nomination aims to elevate Black leaders advocating for racial justice by providing financial awards of $20,000 or $50,000. This initiative connects established and emerging Black leaders and supports their efforts to combat systemic inequalities exacerbated by police brutality and the pandemic. Awardees receive not only funding but also additional resources and support to strengthen their impact in building an equitable and anti-racist society.
Diversity, Equity & Inclusion Black American Services

Educational Scholarships - College or Technical/Trade School Scholarship

Folded Flag Foundation
Private
United States
Unspecified amount
The Folded Flag Foundation offers educational scholarships for college-bound spouses and children of U.S. military members and government employees who died due to combat-related incidents. This program supports tuition, fees, and living expenses for eligible applicants under 26 years old. It aims to assist families in achieving educational goals while navigating the challenges of loss. The scholarships cover various educational expenses, ensuring access to both college and technical training opportunities.
Military & Veterans Services

The General Montgomery (Monty) C. Meigs Scholarship

Folded Flag Foundation
Private
United States
Unspecified amount
The General Montgomery (Monty) C. Meigs Scholarship, offered by the Folded Flag Foundation, honors individuals who embody Monty Meigs' exceptional leadership and dedication. This scholarship is available to high school and college students who display academic excellence and commitment to service. Applicants must submit academic records, a recommendation letter, and a personal essay. Designed to support the next generation of leaders, this scholarship reflects Monty's legacy of service and achievement.
Military & Veterans Services

Repurposing Research for Chicago- Track 1- Investigator Groups

Cures Within Reach
Private
United States
Up to US $125,000
The 'Repurposing Research for Chicago - Track 1 – Health Equity' grant, offered by Cures Within Reach, aims to fund clinical repurposing trials addressing health disparities among underrepresented populations. With a budget of up to $100,000, it encourages trials led by underrepresented researchers or focusing on women's health. The initiative seeks to enhance the quality of life in the Chicagoland area through effective and innovative medical solutions, fostering collaboration across diverse stakeholder groups.
Women's Health Diversity, Equity & Inclusion Health Disparities & Social Determinants of Health +1 more

Repurposing Research for Chicago - Track 2 – Patient Groups

Cures Within Reach
Private
United States
Up to US $125,000
The "Repurposing Research for Chicago - Track 2" grant supports early-stage investigators conducting clinical repurposing trials for unsolved diseases. Researchers must be within 10 years of completing an advanced degree or residency, and trials can utilize telehealth. Funded institutions must be located in the Chicagoland area, with budgets up to $100,000 available. This initiative aims to enhance the quality of life through efficient medical repurposing, connecting various stakeholders to expedite treatment delivery.
Diseases & Conditions Rare Diseases

The Research on Research Security Program

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Research on Research Security Program, funded by the National Science Foundation, aims to foster collaboration between STEM researchers and research security practitioners. It encourages interdisciplinary approaches to enhance evidence-based research on security issues. Proposals can include conferences, workshops, and planning grants, as well as international partnerships, to address U.S. concerns in research security. This initiative is vital for developing a robust community in this emerging field.
Science Engineering Domestic / Homeland Security +1 more

CareQuest Emergent & Relief Fund

Carequest Institute For Oral Health Inc
Private
American Samoa, Guam +4 more
Unspecified amount
The CareQuest Emergent & Relief Fund aims to address the unique challenges faced by historically underserved communities in the healthcare system, particularly in oral health. This fund supports innovative approaches, urgent clinical responses, and immediate relief efforts for community crises. Grants are targeted at organizations demonstrating commitment to equity in health services, ensuring that aid reaches those most in need. With a focus on transformative change, this initiative seeks to enhance access and improve health outcomes across diverse populations.
Disaster Relief / Humanitarian Aid Dental Health Minority Services

On My Way to Kindergarten Program

The Molina Foundation
Private
United States
Unspecified amount in in-kind support
The On My Way to Kindergarten Program offers essential resources to prepare children aged 3-5 for kindergarten. Developed with input from educators, it includes a bilingual activity book and online access to games, songs, and crafts in both Spanish and English. Funded by The Larry and Helen Hoag Foundation, this initiative aims to empower at-risk children and their families, ensuring they have the tools needed for a successful transition into school.
Education - Preschool / Early Learning Early Childhood Development

AISES Indian Motorcycle Academic Scholarship

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Canada +5 more
US $5,000
The AISES Indian Motorcycle Academic Scholarship offers $5,000 annually to support Native students pursuing degrees in STEM fields. Sponsored by the American Indian Science and Engineering Society, this scholarship aims to empower Indigenous students and enhance diversity in STEM. Eligible applicants must be current AISES members, full-time students, and enrolled citizens or descendants of recognized Native tribes. This scholarship not only provides financial assistance but also fosters community and innovation within the STEM landscape.
STEM / STEAM Education Minority Services Native American Services +4 more

South Dakota Grants for Nonprofits Highlights

South Dakota grants for nonprofits provide funding to support rural development, education, public health, and cultural preservation initiatives. The following grants help organizations address community challenges, foster sustainability, and enhance quality of life across South Dakota.


Search Instrumentl's South Dakota Grants Database


Find 106 funding opportunities for nonprofits in South Dakota, with $6.4M available. Instrumentl streamlines the funding process by offering grant-matching tools, deadline alerts, and key insights to help organizations achieve their missions.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : South Dakota Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100+ South Dakota grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

30 South Dakota grants for nonprofits over $25K in average grant size

23 South Dakota grants for nonprofits over $50K in average grant size

23 South Dakota grants for nonprofits supporting general operating expenses

91 South Dakota grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for South Dakota grants for Nonprofits?

Most grants are due in the first quarter.

Q1
34.7%
Q2
24.6%
Q3
19.8%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for South Dakota Grants for Nonprofits?

Grants are most commonly $10,000.

$250 $250 Min.
$10,000 $10 K Median
$89,650 $89.7 K Average
$1,250,000 $1.3 M Max.

Frequently asked questions

A wide variety of funding sources for nonprofits are available in South Dakota. Currently, 100+ are available, totaling $6,365,150. For organizations interested in pursuing grant funding in South Dakota, the median grant size is $10,000. Among these grants, 23 grants support general operating expenses while 91 grants fund projects and programs specifically.

Various organizations and institutions provide grants for the state of South Dakota, including government agencies, private foundations, associations, and more. Here’s a breakdown of where you'll find the most grants available:

  • State & Local Government: The state of South Dakota offers over 29 grants. Many of these funding opportunities focus on agriculture.
  • Private Foundations: Around 43 private foundation grants are available in the state of South Dakota, with focus areas ranging from rural development to health and medicine.
  • Corporate Funders: There are around 17 open corporate grants. These grants mainly focus on agriculture and human and social services.

Whether you go after government grants or foundation grants depends on your grant readiness. Keep in mind that government grants often have large awards but equally large compliance requirements.

Based on the data we have now, the best time to apply for grants in South Dakota is in Q1, which is when about 34.7% of grant deadlines fall. This period offers nonprofits the most opportunities to secure funding. Comparatively, Q3 has the least activity, with only 19.8% of deadlines. To maximize your chances of securing funding, be aware of the peak fundraising periods.

The nonprofit funding landscape throughout South Dakota has shown significant activity over the past several years. Based on the funding reports sent to the IRS, overall grant funding reached $481,503,794 in 2021 and then rose to $619,327,674 in 2022, an increase of about 28.62%. Among all the grants awarded in South Dakota, the most popular focus areas for funding were single-organization support from private grantmaking, single-organization support, professional societies, associations and research institutes, and/or public policy analysis. Likewise, the top counties that received the most funding were Pennington County, Minnehaha County and Todd County.

If you want to start finding more grants, Instrumentl simplifies the entire grant process. You can find grants within South Dakota for your nonprofit while also researching funders, managing deadlines, and keeping on top of everything in our all-in-one platform.

With Instrumentl, you'll get access to over 20,000 live grants and 400,000 funders beyond what you see here in South Dakota. Learn more about Instrumentl’s powerful grant platform.

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