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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

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$2.60B

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$5K

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$2.60B total
$5K median

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Native Public Health Resilience

Indian Health Service
Federal Government
United States
Unspecified amount
The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.
Epidemiology & Public Health Health Care Access & Delivery Native American Services +2 more

NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment and recovery through a robust national infrastructure. Funded by the National Institutes of Health, this initiative focuses on clinical trials that evaluate innovative therapies for stroke patients and those at risk. The program is currently not soliciting applications but encourages the development of collaborations to support the national coordinating center and data management efforts, ultimately improving outcomes for individuals affected by stroke.
Neurological Diseases & Disorders Medical Rehabilitation Preventative Healthcare

NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.
Genetics & Genomics Addiction & Substance Use Disorders Emerging Technology Development

BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.
Engineering Neurological Diseases & Disorders Emerging Technology Development

Limited Competition: BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative, led by the NIH, aims to advance neurotechnologies at institutions with limited NIH funding. This funding opportunity encourages collaboration and knowledge transfer to integrate innovative neurotechnologies into research and training programs. While applications are currently not being solicited, potential applicants should start developing partnerships and projects in preparation for future submissions. This initiative will enhance the dissemination of BRAIN technologies and support novel research practices.
Education - Higher Education Neurological Diseases & Disorders Emerging Technology Development

Stars, Stripes & Skilled Trades

General Motors Foundation Inc
Corporate
United States
US $100,000 - US $500,000

Stars, Stripes & Skilled Trades

General Motors invites eligible 501(c)(3) nonprofit organizations to submit proposals for Stars, Stripes & Skilled Trades, a workforce development initiative designed to support veterans, transitioning service members, and military-connected family members—including spouses—in building lasting careers in manufacturing, automotive, and skilled trades. GM is seeking scalable, results-driven programs that create clear pathways to quality careers while recognizing the experience and leadership that veterans and military families bring to American industry. 

We're looking for existing initiatives that:

  • Serve career-transitioning service members, veterans, and military-connected family members
  • Provide industry-recognized training, certifications, or credentials
  • Connect participants to mentorships, quality jobs, and long-term career pathways in manufacturing, automotive technician roles, or skilled trades.

Grant Range

  • $100,000 | $250,000 | $500,000
Military & Veterans Services

Humanities in Place Grant Program

Mellon Foundation
Private
United States
Unspecified amount

Mellon Foundation

The Andrew W. Mellon Foundation was established in 1969 to strengthen, promote, and defend the arts and humanities as essential to democratic societies. Throughout our history, Mellon has held true to our founding commitments, secure in our conviction that the arts and humanities are essential to the health of a multivocal and democratic society. From our earliest days, we have aspired to build partnerships with our grantees, offering expertise and counsel in addition to funding

In recent years, Mellon has expanded on these core principles by actively prioritizing social justice across all of our grantmaking. This strategic shift builds on our long history of advocating for and investing in expanded access to higher education, humanities, and the arts, and addressing historical inequities in these fields. Our vision for Mellon’s future includes a focus on justice for all in all that we do—rooted in the Foundation’s long-held historic belief in the impact and power of the arts and humanities. At Mellon, we make grants to actively support communities and ideas that unlock the power in the arts and humanities that helps connect us all.

Humanities in Place Grant Program

The Andrew W. Mellon Foundation actively works with our grantee partners and we are deeply immersed in the fields in which we invest. Our grants are designed to activate the spirit of learning through the creation and sharing of bold new ideas and the inspiration felt in art, expression, spaces, and scholarship. 

From Alaska to Guam and the Borderlands to the Midwest, America is a constellation of unique heritages, traditions, and stories. In communities of all sizes, people are striving to expand the ways we can understand and authentically engage with the history that is all around us. Our Humanities in Place grants fund place keepers, artists, institutions, and storytellers who shine a spotlight on historically overlooked sites, and the communities and stories that surround them. In doing so, they help broaden our shared understanding and open new paths to discover what unites us, what makes us unique, and what we can learn from one another.

Humanities & Social Science Historical Records & Archives Community Culture & Heritage

Melton Foundation Action Grants

Melton Foundation
Private
Chile, China +4 more
US $50 - US $2,000

Melton Foundation

The Melton Foundation is an international 501(c)(3) non-profit organization registered in the USA, and a leading proponent of Global Citizenship education and practice worldwide. Established nearly thirty years ago with the credence that collaborations across boundaries can forge sustainable solutions to the world’s most pressing challenges, today, our programs reach millions of young leaders, having crystallized into a network of over 750 life-long Melton Fellows spread across 40+ countries. Our primary operations are in Chile, China, Germany, Ghana, India, and the United States of America, with legal subsidiaries in Bangalore, India; Jena, Germany; Temuco, Chile; and Accra, Ghana. 

Through our fellowship and collaborative programs we promote and enable global citizenship as a way for individuals and organizations to work together across boundaries of place and identity to solve challenges in an interconnected world.

Melton Foundation Action Grants

The Melton Foundation offers grants year-round to support Melton Fellows in developing skills, perspective and wider networks to further their capacity as global citizens and contribute towards building an equitable, sustainable, and peaceful world.

In almost 10 years of granting, more than 100 Fellows’ initiatives have been awarded with a Melton Foundation grant to

  • Build awareness and/or further awareness raising around global issues and the Sustainable Development Goals (SDGs),
  • Develop individual and collective responsibility for sustained, collaborative action,
  • Grow capacity to collaboratively drive and sustain social impact at the local and/or global level,
  • Further the design, implementation and evaluation of collaborative actions that embody the spirit of global citizenship practice and further social impact, or
  • Support coordinated social-impact efforts in a particular or across (emerging) Melton Foundation Hub regions to promote global citizenship practice (s) and the organization’s mission.
Sustainability Human & Social Services International / Foreign Affairs +3 more

Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership

National Oceanic and Atmospheric Administration (NOAA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Climate Program Office (CPO) FY2026 Earth System Science and Services Partnership (ESSSP) aims to enhance NOAA's mission through collaborative research and activities. It focuses on understanding changes in Earth's systems and their impacts on ecosystems and communities. Eligible applicants include academic institutions offering doctoral degrees in NOAA-related sciences. The total funding available is approximately $10 million, supporting initiatives that encompass research, data evaluations, and stakeholder engagement.
Earth Science Atmospheric Sciences Climatology +1 more

R3PEATS Grassroots Rigor Projects: Individual Metascience and Individual Laboratory Capacity-Building (RP1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R3PEATS Grassroots Rigor Projects, funded by the NIH, aim to enhance research practices through two project types: Metascience and Laboratory Capacity-Building. Metascience projects focus on creating tools and metrics to promote high-quality research, while Laboratory Capacity-Building projects help labs adopt new techniques and share data that influence research outcomes. This initiative is part of a broader effort to improve rigor, replicability, and reproducibility in scientific research.
Science Emerging Technology Development Nonprofit Growth & Development

R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R3PEATS Multi-Team Triangulation initiative supports collaborative research teams to explore a central biomedical question using diverse methods and model systems. It emphasizes the importance of identifying biological variability and ensuring the robustness of findings through replication strategies. This program is part of the NIH Common Fund's Rigor, Replicability, & Reproducibility to Promote Excellence in Science, aiming to enhance the accuracy and translation of scientific discoveries.
Science

R3PEATS Rigor Scholar Cohort Awards (K12)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The R3PEATS Rigor Scholar Cohort Awards (K12) are designed to empower early-career researchers by enhancing their skills in rigorous scientific practices. This initiative promotes collaboration across institutions to develop best practices in research methodologies, including preregistration and randomization. Participants will gain essential training to ensure excellence and transparency in scientific research, aligning with the NIH's commitment to improve replicability and reproducibility in the field.
Education - Higher Education Medical Education & Professional Training

Nehemiah Atkinson Humanitarian Grant

Dennis Van der Meer Tennis Foundation
Association/Society
United States
Up to US $5,000

Dennis Van der Meer Tennis Foundation

A 2021 International Tennis Hall of Famer, Dennis was the founder of the Professional Tennis Registry Foundation (PTR Foundation), now called Dennis Van der Meer Tennis Foundation, Professional Tennis Registry (PTR), and the Van Der Meer Tennis University.

Dennis Van der Meer Tennis Foundation is a nonprofit organization exempt from federal income tax under Section 501(c)(3) of the Internal Revenue Code. The Dennis Van der Meer Tennis Foundation provides support to deserving individuals and organizations globally. The foundation is also focused on bringing tennis within reach to countless people worldwide.

Nehemiah Atkinson Humanitarian Grant

This grant reflects the Foundation’s dedication to giving and serving others. It is awarded to individuals who have shown an extraordinary commitment to enhancing the lives of those around them.

The Foundation supports projects that promote and preserve the legacy, vision, and spirit of our founder, Dennis Van der Meer. We will only consider funding for educational, life enrichment, mentoring, and tennis programs.

Academic Success & Enrichment Tutoring & Mentoring Tennis

Newman-Galas Entrepreneurial Initiative

Fannie and John Hertz Foundation
Private
United States
Up to US $25,000

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Newman-Galas Entrepreneurial Initiative

The Harold Newman and David Galas Entrepreneurial Initiative provides financial and professional support to Hertz Fellows who propose the most innovative entrepreneurial projects, with particular emphasis on collaboration among fellows. Awardees receive investments up to $25,000 to fund their work and receive mentoring from successful entrepreneurs within the fellows community.

Fueling Entrepreneurs

The initiative was established by honorary Hertz Fellow Harold Newman, a former member of our board of directors and a long-time supporter of and generous donor to the foundation. Newman changed the name to the Harold Newman and David Galas Entrepreneurial Initiative in honor of David Galas, a Hertz Fellow and chairman of the board. Through Newman’s substantial endowment, this award has helped enterprising fellows co-found 11 companies and develop new technologies with real-world impact.

The funds are provided with no strings attached, only the expectation that project leaders will be motivated to share their success with the foundation.

Entrepreneurship Emerging Technology Development Engineering +2 more

Hertz Thesis Prize

Fannie and John Hertz Foundation
Private
United States
US $5,000

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Thesis Prize

The Hertz Thesis Prize recognizes fellows who publish exemplary doctoral theses with applications to real-world problems. Winners receive a $5,000 honorarium.

Exemplary Graduate Work

Since 1981, more than 60 fellows have been recognized with the Hertz Thesis Prize. Much of their work has led to successful patents, the formation of influential companies and contributed solutions to some of our most pressing challenges.

Education - Higher Education Engineering Mathematics +1 more

Hertz Foundation Travel Fund

Fannie and John Hertz Foundation
Private
Countries
US $2,000 - US $5,000

About the Hertz Foundation

Empowering the Nation’s Most EXCEPTIONAL Innovators

The Hertz Foundation identifies and empowers the nation’s most exceptional innovators in science and technology, fueling a lifelong community dedicated to solving our most pressing problems.

Hertz Community

Awards & Recognition

We’ve established several awards to recognize and support Hertz community members who are accelerating solutions to significant real-world challenges, either through their individual careers or volunteering to strengthen the Hertz Foundation’s work. In addition to providing financial and professional support at a critical time, we also hope to generate more awareness within the Hertz community and inspire collaborations that build on the momentum.

Hertz Foundation Travel Fund

The Hertz Foundation Travel Fund provides financial support to Hertz Fellows to advance their professional growth through conference travel and interdisciplinary engagement. Awardees receive a lump sum of $2,000 for domestic or $5,000 for international travel.

Supporting professional development

Established in 2025, this funding provides Fellows with critical support to enhance their career and professional development. Funding is designated to support travel to attend technical conferences, interdisciplinary or entrepreneurial convenings and workshops or seminars that catalyze new career paths, research directions or cross-sector collaborations.

Engineering Mathematics Science +1 more

Naomi Chazan Global Activism Fellowship

New Israel Fund
Private
United States
Unspecified amount

About NIF

Advancing Equality for All Israelis

The New Israel Fund (NIF) helps Israel live up to its founders’ vision of a society that ensures complete equality to all its inhabitants. Our aim is to advance liberal democracy, including freedom of speech and minority rights, and to fight the inequality, injustice and extremism that diminish Israel.

From Israel’s first rape crisis centers, to fighting discrimination, NIF-funded organizations have driven positive social change and furthered justice and equality. NIF has provided over $350 million to more than 950 organizations since our inception in 1979.

Naomi Chazan Global Activism Fellowship

Want to travel to Israel/Palestine while advancing equality, democracy, and peace for all?

The New Israel Fund’s Naomi Chazan Global Activism Fellowship offers a one-of-a-kind opportunity to visit Israel/Palestine, meet frontline Israeli and Palestinian activists, and learn about issues of war, peace, and inequality by seeing the reality on the ground. 

Fellows will visit Israel/Palestine on November 3-10, 2026.

This trip is a great opportunity to learn alongside peers and friends (ages 21 – 35). NIF is based on the simple idea that those of us who share a commitment to Israel/Palestine and to progressive values can join together to work for equality, freedom, and human rights. You will join a cohort of participants from the U.S. and Canada building relationships across borders to be sustained for years to come.

Following the trip, participants are expected to organize at least two NIF events in their home communities, with support from NIF staff. These events could look like a report-back highlighting the participants’ learnings from the trip, educational programs featuring NIF grantees/partners, or something else entirely that is tailored to the intellectual, emotional, and spiritual needs of the fellow’s communities.

The program is subsidized by generous donors in the NIF community. All “on-the-ground” costs—your hotel accommodation and almost all meals—will be covered by NIF. Participants are responsible for purchasing their own airfare and travel/health insurance. If the cost of airfare is a barrier for you, please apply anyway. Limited airfare subsidies may be available.

Social Justice / Human Rights International / Foreign Affairs Cross-Cultural Understanding & Exchanges +3 more

Matthew Power Literary Reporting Award

Arthur L. Carter Journalism Institute
Association/Society
Countries
US $15,000

About Us

The Arthur L. Carter Journalism Institute at NYU

We want to educate those who agree. Opportunities abound in the media world, but at NYU Journalism, the opportunity to do compelling work that informs, engages, and matters to the societies in which we live drives our faculty, motivates our students, and shapes our approach.

Those who find this their calling will discover encouragement, support, and an endless amount to learn at NYU. Our graduates are able to work anywhere their talents take them, and they do. Students come here not only to gain competence in the journalist’s craft but also the tools to make it better than it is. And those two things are the essence of what we teach.

Matthew Power Literary Reporting Award

Matthew Power was an award-winning journalist who reported empathetically on the human condition. He died in March 2014, while on assignment in Uganda.

About the Award

The Matthew Power Literary Reporting Award is a grant of $15,000 to support the work of a promising early-career nonfiction journalist on a story that uncovers truths about the human condition.

Offered for the first time in 2015, the Award has been endowed by individuals and organizations touched by the life and work of Matthew Power, a wide-roving and award-winning journalist who sought to live and share the experience of the individuals and places on which he was reporting. Power, a longtime friend of the Arthur L. Carter Journalism Institute, died in March 2014, while on assignment in Uganda.

The award proceeds from the recognition that many important stories need to be reported from afar, and that publications do not always have the resources to send a journalist where the story is. The money need not be used exclusively for travel, but we expect that most successful applications will include such expenses. A panel of NYU journalism professors, outside writers, and editors will review the proposals. Finalists will be asked to take part in an interview online.

The judges will be interested in perpetuating Power’s legacy, as his former editor Roger Hodge put it, of “strong, character-driven narratives with detailed scenes and lyrical description.” Power was always open to the absurdity that often attends politics and international affairs; he was always searching, as he put it, for “the human truth beneath the sorry facts.” Power’s ultimate ambition, he added, was literary beauty.

That said, judges will be looking for a journalist as singular in his or her own approach as Power was in his. In addition to longform print projects, we will consider audio projects involving substantial reporting and running over 20 minutes in length. The award will not fund proposals to report on armed conflicts where journalists are already imperiled, nor projects that are mainly investigatory. The winner will normally receive visiting scholar privileges at NYU, including library access.

Humanities & Social Science Journalism

Literary Arts Project Grants

South Arts, Inc.
Private
United States
Up to US $5,000

Literary Arts Project Grants

As part of its Literary Arts Initiative, South Arts is pleased to announce Literary Arts Project Grants supporting literary arts organizations and small presses that focus on contemporary literary arts.

These grants advance South Arts’ commitment to amplifying the literary traditions and artistic practices of the American South by directly supporting the development, production, and public engagement of high-quality literary projects.

Literary Arts Project Grants support projects in poetry, fiction, creative or literary nonfiction, young readers’ literature, and drama (scriptwriting). Projects must demonstrate artistic excellence, editorial rigor, and meaningful public or community impact.

Award Amount

South Arts will award up to $5,000 per project to eligible literary arts organizations and small presses.

Writing & Literature Poetry Documentaries

The Hendrix-Murphy Book Award

Hendrix-Murphy Foundation
Association/Society
United States
Unspecified amount

Hendrix-Murphy Foundation

Enhancing literature & language at Hendrix College since 1978.

In homage to Bertie Wilson Murphy’s passion for the study and appreciation of literature and language, the Hendrix-Murphy Foundation at Hendrix College was founded in 1978 with an endowment by her son, Charles H. Murphy, Jr., former CEO of Murphy Oil Corporation. Mrs. Murphy was a 1905 graduate of Galloway Women’s College in Searcy, Ark., which merged with Hendrix College in Conway in the 1930s. Charles H. Murphy, Jr., was a member of the Hendrix Board of Trustees and served as chair. 

The Foundation's programs are overseen by a Board of Directors that is headed by the president of the College and includes Murphy family members, the provost, and representatives from the Hendrix Board of Trustees.

The Hendrix-Murphy Book Award

Hendrix is proud to offer the Hendrix-Murphy Book Award to an outstanding high school junior who demonstrates distinguished scholarship or leadership in literary studies (English, creative writing, foreign languages, or drama).

Hendrix-Murphy Book Award recipients will receive a copy of Poems to Read: A New Favorite Poems Anthology, edited by Robert Pinsky and Maggie Dietz.

Students may be nominated by their English, languages, creative writing, or drama teacher or guidance counselor by using the required form.

Writing & Literature Linguistics Language Education +1 more

1890 Institution Teaching, Research, and Extension Capacity Building Grants Program (363796)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
United States
US $50,000 - US $750,000
The 1890 Institution Teaching, Research, and Extension Capacity Building Grants Program aims to enhance the capabilities of eligible institutions by fostering collaboration with federal and non-federal entities. This initiative supports the White House's commitment to promote excellence at Historically Black Colleges and Universities (HBCUs). By strengthening institutional teaching, research, and extension capacities, the program helps ensure that HBCUs can effectively contribute to innovative solutions in education and community development.
Education - Higher Education Agriculture Workforce Preparation & Job Readiness +1 more

Cancer Prevention and Control Programs for State, Territorial, and Tribal Organizations (363814)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The Cancer Prevention and Control Programs aim to enhance cancer outcomes by funding partnerships among national, state, territorial, and tribal organizations. These initiatives focus on evidence-based strategies for cancer surveillance, prevention, and control, specifically targeting breast and cervical cancer screening for underserved populations. Through collaboration, the program seeks to improve clinical services and cancer survivorship, ultimately striving towards the vision of 'All People Free of Cancer' by leveraging resources and community involvement.
Cancer / Oncology Epidemiology & Public Health Health Care Access & Delivery +2 more

NIH Director's New Innovator Award (DP2 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $475,000
The NIH Director's New Innovator Award supports creative early-stage investigators pursuing innovative research with transformative potential for science relevant to the NIH mission. Applications are encouraged across all NIH-related fields, enhancing support for emerging talent. This award is part of the NIH Common Fund's High-Risk, High-Reward Research Program, which aims to cultivate groundbreaking research and foster the next generation of scientists.
Health & Medicine Medical Education & Professional Training Emerging Technology Development

Residential Treatment for Pregnant and Postpartum Women

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Residential Treatment for Pregnant and Postpartum Women program aims to deliver essential services to women facing substance use disorders. By offering comprehensive residential treatment options, the program supports both recovery and the well-being of mothers and their children. Funded by the Substance Abuse and Mental Health Services Administration, this initiative addresses the unique challenges of pregnant and postpartum women, ensuring they receive the care necessary for a successful recovery journey.
Addiction & Substance Use Disorders Drug Use Disorder Women's Health +2 more

Providers Clinical Support System – Universities

Substance Abuse and Mental Health Services Adminis
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.
Education - Higher Education Workforce Preparation & Job Readiness Addiction & Substance Use Disorders +1 more

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $700,000
The NIH Director's Pioneer Award (DP1) encourages innovative research by funding exceptional scientists. This award is designed for groundbreaking projects that diverge from the investigator's current work and address significant scientific challenges relevant to the NIH mission. Applications are invited across all NIH-relevant fields, promoting high-risk, high-reward research that could transform our understanding of critical scientific areas.
Science Health & Medicine Emerging Technology Development

NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $350,000
The NIH Director's Early Independence Award empowers exceptional early-career researchers to embark on independent research careers immediately after their doctoral degree or post-graduate clinical training. This initiative accelerates the transition to independence, promoting innovative research across various fields aligned with the NIH mission. As part of the NIH Common Fund's High-Risk, High-Reward Research Program, it encourages groundbreaking studies that could significantly advance health-related knowledge.
Science Health & Medicine Medical Education & Professional Training +1 more

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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