Upcoming Webinar
Instrumentl Fall Launch: Grant Work, Leveled Up.
Thu, Oct 29 or Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,514 Results based on applied filters

The Hearst Journalism Awards Program - Audio – Journalism Podcast – News and/or Features

William Randolph Hearst Foundation
Private
United States
Unspecified amount
The Hearst Journalism Awards Program, established in 1960, supports journalism education by awarding scholarships to outstanding undergraduate students. With $700,000 available, this program includes competitions across writing, photojournalism, audio, television, and multimedia categories. Each participating university can submit two entries per competition, fostering excellence in journalism. The Hearst Foundation, a long-standing supporter of educational initiatives, underlines the importance of quality journalism and supports students actively engaged in media.
News Media & Communications Journalism

The Hearst Journalism Awards Program - Television - Television I – Features

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education at the college level, offering scholarships for outstanding student work. With up to $700,000 in awards, it features various competitions in writing, photojournalism, audio, television, and multimedia. Open to undergraduate journalism majors at accredited institutions, the program encourages campus media participation. The Hearst Foundation, a philanthropic organization, has contributed over a billion dollars to education and the arts, reinforcing its commitment to nurturing future journalists.
Television

The Hearst Journalism Awards Program - Television - Television II – News

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education at the collegiate level by offering scholarships for outstanding performance. The 2024-2025 program includes 14 competitions across various media forms, with awards totaling up to $700,000. Participation is open to undergraduate journalism majors and minors at ACEJMC-accredited institutions. The program aims to encourage excellence in journalism and provides financial support to both students and their schools.
Television News Media & Communications

The Affirm Cares Employee Foundation Grant

Affirm Cares
Private
American Samoa, Guam +4 more
Unspecified amount
The Affirm Cares Employee Foundation Grant, established by Affirm, aims to support non-profit organizations making a significant impact in financial literacy, community enrichment, and technology education. Grants range from $1,000 to $10,000, focusing on sustainable initiatives that empower communities and alleviate housing insecurity. Eligible applicants must be 501(c)(3) designated non-profits operating within the U.S. The foundation prioritizes measurable outcomes in its funding efforts, fostering civic engagement and vibrant communities.
Homelessness Services Civic Engagement & Education Financial Literacy +5 more

The Hearst Journalism Awards Program - Multimedia - Multimedia I – Narrative Video Storytelling

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education by awarding scholarships to exceptional undergraduate students. With up to $700,000 available in various competitions, including writing, photojournalism, and multimedia, it encourages participation from students in ACEJMC-accredited institutions. The program aims to foster talent and innovation in journalism, ensuring a diverse range of voices is represented in the media landscape. The Hearst Foundation continues to invest in the future of journalism through this esteemed initiative.
Media Arts Writing & Literature

The Hearst Journalism Awards Program - Multimedia - Multimedia II – Innovative Journalism

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports undergraduate journalism education with up to $700,000 in awards through various competitions. Open to ACEJMC-accredited students, it includes writing, photojournalism, audio, television, and multimedia contests. Each participating university can submit two entries per competition, promoting excellence in journalism while providing schools with stipends. While primarily for journalism majors, exceptions exist for photojournalism entrants, fostering inclusivity and creativity in the field.
Media Arts Journalism

The Hearst Journalism Awards Program - Multimedia - Multimedia III – Digital News or Enterprise Story – Individual

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program, established in 1960, supports journalism education through scholarships and competitions. With up to $700,000 in awards across various categories, it encourages undergraduate journalism majors and minors from accredited institutions to showcase their work. The program includes multiple writing, photojournalism, audio, television, and multimedia competitions, providing a platform for emerging journalists to gain recognition and experience in their field.
Media Arts Writing & Literature News Media & Communications +1 more

The Hearst Journalism Awards Program - Multimedia - Multimedia IV – Digital News or Enterprise Story – Team

William Randolph Hearst Foundation
Private
United States
US $1,000 - US $3,000
The Hearst Journalism Awards Program offers significant support for aspiring journalists, providing scholarships and recognition for excellence in various media formats. Established in 1960 by the William Randolph Hearst Foundation, the program includes multiple competitions in writing, photojournalism, audio, television, and multimedia. With up to $700,000 in awards, it encourages undergraduate students at accredited institutions to showcase their talents, fostering the next generation of journalistic talent.
Writing & Literature Media Arts News Media & Communications

No Kid Hungry Grant

Share Our Strength
Private
United States
Unspecified amount
The No Kid Hungry Grant, provided by Share Our Strength, aims to support schools and community groups in ensuring children have access to nutritious meals. Grants are allocated for essential equipment rather than food, addressing the unique needs of programs serving children. With a focus on reducing financial barriers, the initiative prioritizes funding for the School Breakfast Program and summer meals, ultimately striving for equitable access to resources that help combat childhood hunger and promote community engagement.
Food Access & Hunger

Skoll Awards

The Skoll Foundation
Private
United States
Unspecified amount
The Skoll Awards for Social Innovation, presented by the Skoll Foundation, recognize social innovators addressing root societal problems. Each awardee receives $2 million in unrestricted funding and joins a global community of leaders dedicated to significant social change. The foundation focuses on key areas such as health systems, effective governance, inclusive economies, racial justice, and climate action. Nominations are made through a multi-year sourcing process, ensuring that candidates align closely with the foundation's mission.
Governance & Democracy Economics Health Care Access & Delivery +2 more

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity from the US Department of Health and Human Services, specifically the National Institutes of Health, aims to examine the effectiveness of family navigation models that divert non-urgent mental health concerns from emergency departments. The initiative seeks to enhance mental health service engagement, provide necessary resources, and support families in overcoming barriers to help-seeking. Key deadlines for applications range from February 2025 to October 2027.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional) (357379)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity aims to advance research on how work impacts health disparities among U.S. populations. It invites innovative proposals that explore the interplay between occupation and health outcomes, particularly in communities experiencing health and healthcare inequalities. Deadlines for applications span from February 2025 to October 2027, encouraging timely submissions for various categories including standard and AIDS-related grants.
Health Disparities & Social Determinants of Health

Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
This NOFO aims to enhance research on the effectiveness and implementation of family navigation models that divert non-urgent mental health concerns from emergency departments. It will focus on tools for triaging mental health acuity, engaging families with necessary services, and addressing barriers to help-seeking. Important deadlines for grant applications range from February 2025 to October 2027, with optional Letters of Intent encouraged thirty days prior to each due date.
Mental Health & Psychiatric Diseases Children’s Mental Health Emergency Medical Care & Services

David E. Rogers Student Fellowship Award

New York Academy Of Medicine
Private
United States
US $4,000
The David E. Rogers Student Fellowship Award, offered by the New York Academy of Medicine, aims to enhance the educational journey of medical and dental students through impactful community health projects. This initiative supports research endeavors during the summer, providing stipends of $4,000 for up to five selected projects. Eligible candidates must be U.S. citizens or authorized residents, pursuing research that addresses health disparities and the needs of underserved populations.
Dental Health Medical Education & Professional Training Epidemiology & Public Health +2 more

2027 Vilcek Prizes for Creative Promise in Biomedical Science

The Vilcek Foundation Inc
Private
United States
US $50,000
The 2026 Vilcek Prizes for Creative Promise in Biomedical Science will award three $50,000 prizes to exceptional young immigrant scientists in the U.S. This prestigious prize recognizes innovative research contributions in biomedical science. Eligible candidates must be under 38 years old, hold a doctoral degree, and have made significant achievements in their field. The Vilcek Foundation aims to highlight the impact of immigrant scientists on the advancement of biomedical research, fostering diversity and excellence.
Chemistry Biology Bioengineering +8 more

Core Research Grants: Future of Work

Russell Sage Foundation
Private
United States
Up to US $200,000
The Future of Work program by the Russell Sage Foundation investigates the decline in quality of low-wage jobs in the U.S. It explores factors such as outsourcing, immigration, union decline, and technological changes. Current research focuses on minimum wage impacts, offshoring effects, and job search behaviors influencing employment outcomes, particularly for women and minorities in the post-recession labor market. This grant aims to enhance understanding of these critical issues affecting low-education workers.
Employment Services Workers’ Rights

Core Research Grants: Race, Ethnicity, and Immigration

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation's Core Research Grants program focuses on Race, Ethnicity, and Immigration, aiming to foster interdisciplinary research on the changing demographics of the U.S. population. This initiative encourages innovative collaboration among social scientists to enhance research quality and support the ideals of a pluralistic society. By building on insights from previous programs, it seeks to address critical questions concerning race and ethnicity within the context of immigration.
Immigration & Refugee Rights Racial / Ethnic Justice & Rights Humanities & Social Science

Core Research Grants: Social, Political, and Economic Inequality

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation’s Core Research Grants program addresses social, political, and economic inequalities in the U.S. It investigates the factors contributing to these disparities and their impact on various outcomes, including education and civic participation. Launched in 2001 and renamed in 2018, the program aims to enhance understanding of how inequalities affect mobility and representation. Researchers with a doctorate or substantial experience are encouraged to apply, fostering high-level scholarly research in this critical field.
Humanities & Social Science Economics Political Science +2 more

Core Research Grants: Behavioral Science and Decision Making in Context

Russell Sage Foundation
Private
United States
Up to US $200,000
The Russell Sage Foundation's Core Research Grants support innovative research in Behavioral Science and Decision Making. This program emphasizes interdisciplinary approaches, inviting insights from economics, psychology, sociology, and law to enhance our understanding of decision-making processes across various societal contexts. Applications are open to scholars with a doctorate, focusing on critical issues such as policing, housing, and immigration, while encouraging a blend of theoretical and empirical research to inform public policy.
Economics Psychology Political Science +9 more

Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed) (357250)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,500,000
The Chemical Countermeasures Research Program (CCRP) Initiative aims to support vital research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, including fentanyl and its combinations. This funding opportunity encourages studies that enhance understanding and mitigation strategies for these substances, focusing on both immediate and long-term health impacts. Applications are due by 5:00 PM local time, with optional Letters of Intent accepted 30 days prior to the proposal deadline.
Drug Use Disorder Addiction & Substance Use Disorders Drug Safety

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (357256)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for clinical trials and biomarker studies aimed at stroke treatment, recovery, and prevention. This funding opportunity encourages collaborative projects that validate promising interventions and scientific aims within the NIH StrokeNet framework. Key deadlines for submissions span from February 2025 to November 2026, with support provided by the National Coordinating Center and Regional Coordinating Centers to ensure efficient study implementation and participant recruitment.
Stroke

NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.
Biology Health & Medicine Medical Education & Professional Training

Applied regulatory science research to evaluate and treat cardiotoxicity of oncology therapeutics

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Unspecified amount
This grant aims to enhance applied regulatory science research for the evaluation and treatment of cardiotoxicity associated with oncology therapeutics. The initiative will facilitate collaboration with the FDA to develop effective methodologies and solutions, ensuring that research outcomes are directly relevant to regulatory decision-making. Key activities include regular communication with funded investigators and a focus on improving detection and management of cardiotoxicity, ultimately leading to impactful publications and presentations.
Cancer / Oncology Drug Safety

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) (357282)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,125,000
The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.
Biology Health & Medicine Medical Education & Professional Training

Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) (357288)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is inviting applications for the Screening, Brief Intervention, and Referral to Treatment or Prevention (SBIRT/P) program. This funding opportunity aims to explore innovative methods for addressing alcohol, tobacco, and other drug use among adults facing health disparities. The initiative seeks research proposals that will implement and evaluate SBIRT/P strategies in collaboration with healthcare and community partners. This approach is crucial for enhancing public health and ensuring effective interventions.
Preventative Healthcare Health Disparities & Social Determinants of Health Addiction & Substance Use Disorders +3 more

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required) (357301)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Multi-Site Feasibility Clinical Trials (R01) invites applications for clinical trials focused on mind and body interventions. This program emphasizes the need for multisite feasibility studies to gather essential data for future efficacy trials. The initiative is designed to enhance public health by addressing gaps in scientific knowledge related to the delivery, recruitment, and data collection of integrative health approaches. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health

Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required) (357303)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites applications for investigator-initiated clinical trials that deliver complementary and integrative health interventions remotely or via mobile health technologies. Emphasizing no in-person contact, the trials should demonstrate feasibility, safety, and potential clinical benefits. A Plan for Enhancing Diverse Perspectives is required for submission, and applicants are encouraged to consult with NCCIH contacts before applying. Deadlines for submissions range from February 2025 to October 2026.
Integrative & Alternative Health Telemedicine & Telehealth

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

Browse Missouri Grants by Focus Area

Filter Missouri Grants by Location

Browse Grants by Counties within Missouri

Adair County Andrew County Atchison County Audrain County Barry County Barton County Bates County Benton County Bollinger County Boone County Buchanan County Butler County Caldwell County Callaway County Camden County Cape Girardeau County Carroll County Carter County Cass County Cedar County Chariton County Christian County Clark County Clay County Clinton County Cole County Cooper County Crawford County Dade County Dallas County Daviess County DeKalb County Dent County Douglas County Dunklin County Franklin County Gasconade County Gentry County Greene County Grundy County Harrison County Henry County Hickory County Holt County Howard County Howell County Iron County Jackson County Jasper County Jefferson County Johnson County Knox County Laclede County Lafayette County Lawrence County Lewis County Lincoln County Linn County Livingston County Macon County Madison County Maries County Marion County McDonald County Mercer County Miller County Mississippi County Moniteau County Monroe County Montgomery County Morgan County New Madrid County Newton County Nodaway County Oregon County Osage County Ozark County Pemiscot County Perry County Pettis County Phelps County Pike County Platte County Polk County Pulaski County Putnam County Ralls County Randolph County Ray County Reynolds County Ripley County Saline County Schuyler County Scotland County Scott County Shannon County Shelby County St. Charles County St. Clair County Ste. Genevieve County St. Francois County St. Louis City St. Louis County Stoddard County Stone County Sullivan County Taney County Texas County Vernon County Warren County Washington County Wayne County Webster County Worth County Wright County

Browse Grants by Major US Cities within Missouri

Explore Grants Outside of Missouri

Browse Grants by Other States or Regions