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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,514 Results based on applied filters

Collaborative Capacity Program - Standard Grant: Community Partner Applicants

National Forest Foundation (NFF)
Private
United States
US $10,001 - US $75,000
The National Forest Foundation’s Collaborative Capacity Program offers financial awards to enhance collaboration among communities, tribes, and the Forest Service. Aimed at improving wildfire resilience and forest health, these grants support efforts that lead to long-term stewardship outcomes. Funding ranges from $10,001 to $75,000, with a 20% match required. The program seeks to empower local partners to develop strategic plans and strengthen collaborative initiatives, ultimately benefiting National Forest System lands.
Recreation Forestry Fire Ecology +1 more

Collaborative Capacity Program - Standard Grant: Tribal Applicants

National Forest Foundation (NFF)
Private
United States
US $20,000 - US $50,000
The National Forest Foundation’s Collaborative Capacity Program offers financial support to enhance collaboration among local communities and partners, focusing on improving wildfire resilience and forest health. Grants range from $10,001 to $75,000, with a 20% cash or in-kind match requirement. The program aims to foster long-term stewardship outcomes for National Forest System lands, ensuring benefits to both forests and local economies through collaborative efforts.
Recreation Forestry Fire Ecology +1 more

St. Louis County Port Authority Community Investment Fund

St. Louis County Port Authority Grant
State/Local Government
St. Louis County, Missouri
Up to US $300,000
The St. Louis County Port Authority Community Investment Fund enhances economic and community development by providing support to projects that benefit underserved areas. Key priorities include business retention and expansion, neighborhood development, entrepreneurship, and real estate redevelopment. The fund focuses on initiatives that promote economic opportunities for historically underserved individuals and communities, leveraging resources from local partnerships, including rental payments from Penn National Gaming for the River City Casino.
Community Development & Revitalization Business Education Business Development +6 more

Forecast for Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
The Forecast for Clinical Trial Readiness for Rare Diseases (R21) aims to enhance the development and testing of diagnostics and therapeutics for rare diseases. This funding opportunity invites researchers to facilitate clinical trial readiness by developing rigorous biomarkers and clinical outcome measures. Through collaborative efforts with various stakeholders, NCATS seeks to improve the efficiency of moving candidate therapeutics towards clinical trials, ultimately increasing the likelihood of successful treatments for rare diseases.
Rare Diseases

NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
The NIA Expanding Research in AD/ADRD Postbaccalaureate Research Education Program aims to enhance the research workforce by providing intensive research experiences for recent graduates. This initiative supports early-stage investigators in Alzheimer's Disease and related dementias, addressing a critical shortage of researchers in the field. Participants engage in independent research, mentorship, and professional development, equipping them with skills necessary for advanced degrees and research careers in aging and dementia. The program fosters innovation and interdisciplinary collaboration essential for advancing AD/ADRD research.
Aging / Gerontology Dementia & Alzheimer’s Disease Medical Education & Professional Training

Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,300,000
This funding opportunity supports the establishment of Animal and Biological Material Resource Centers to enhance biomedical research through the provision of specialized laboratory animals and related resources. It seeks to promote scientific rigor and reproducibility by facilitating the development of new methodologies that complement traditional research. Centers must align with multiple NIH Institutes and focus on integrating innovative approaches like cell culture and computational models, fostering collaboration and advancement in human disease modeling.
Biology

Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The NIH invites applications for research projects focusing on developing and enhancing models for studying human health and diseases. Projects must demonstrate broad applicability across multiple NIH Institutes, addressing diseases that impact various organ systems. Successful proposals will outline the need for resources and their potential impact on diverse scientific disciplines. Applications targeting specific diseases or with limited NIH relevance will not be accepted. Deadline for submission is 5:00 PM local time.
Medical Technology, Devices, and Equipment Biomedical informatics Diseases & Conditions

NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $200,000
The NIA Expanding Research in AD/ADRD Summer Research Education Program supports the recruitment of early-stage investigators and aims to provide hands-on research experiences in Alzheimer's Disease and related dementias. Targeting high school students, undergraduates, and science teachers, the program enhances STEM education through authentic research opportunities and educational activities. By fostering early exposure to research, it aims to stimulate interest in AD/ADRD careers and address workforce shortages in this critical field.
Dementia & Alzheimer’s Disease STEM / STEAM Education

Carnegie-Whitney Grant

American Library Association (ALA)
Association/Society
United States
Up to US $5,000
The Carnegie-Whitney Grant, established by Andrew Carnegie in 1902, supports the creation of bibliographical aids for American libraries. Grants cover the preparation costs of reading lists and indexes, enhancing access to library resources. Eligibility requires projects to stimulate library use and be broadly appealing, with a focus on national distribution. Notably, completed works and projects under contract are ineligible. The fund encourages innovation in library resource development, welcoming applications from individuals and organizations.
Library & Information Science Library Services

Baker and Taylor YALSA Conference Grant

American Library Association (ALA)
Association/Society
United States
US $1,000
The Baker and Taylor YALSA Conference Grant provides two $1,000 awards to librarians working with young adults, enabling them to attend the Annual Conference for the first time. One grant supports a school librarian, while the other is for a public library librarian. Applicants must be current members of ALA/YALSA, with prior membership preferred for at least two years, and must have between one to ten years of experience working with teenagers.
Library Services

Implementing Shared Decision Making in Hemophilia Patient Care

Pfizer, Inc.
Corporate
United States
Up to US $30,000
The Shared Decision Making in Hemophilia Patient Care grant program, funded by Pfizer, aims to enhance patient outcomes through Quality Improvement projects that integrate shared decision-making tools into hemophilia care. This initiative encourages multidisciplinary collaboration to address healthcare disparities and empower patients in their disease management. Eligible organizations include healthcare institutions and professional schools, fostering innovative approaches to improve care for individuals living with hemophilia.
Hematological Systems

Jason Reynolds / Simon & Schuster Travel Grant

American Library Association (ALA)
Association/Society
United States
Up to US $3,000
The Jason Reynolds / Simon & Schuster Travel Grant supports five black/African American youth and teen services librarians annually. Each grant, ranging from $1500 to $3000, covers expenses for travel, housing, registration, and attendance at the ALA Annual Conference, including the Coretta Scott King Awards Breakfast. This initiative aims to empower underrepresented librarians in their professional development and community engagement.
Library Services Black American Services

Clinical Research Training Scholarship in Parkinson's Disease

American Academy Of Neurology Institute
Private
Countries, United States
Up to US $150,000
The Clinical Research Training Scholarship in Parkinson's Disease, funded by the Parkinson's Foundation and the American Brain Foundation, supports young investigators in clinical studies related to Parkinson's disease. Offering $65,000 annually for two years, plus an additional $10,000 for education and research costs, this award aims to foster rigorous clinical research. Eligible applicants must have an MD, PhD, or equivalent degree and be AAN members, focusing on patient-oriented research with human subjects.
Neurological Diseases & Disorders Parkinson’s Disease

Center for the History of Family Medicine Oral History Grant

American Academy of Family Physicians Foundation
Corporate
United States
Up to US $3,000
The AAFP Foundation's Center for the History of Family Medicine Oral History Grant offers up to $3,000 annually for oral history interviews in family medicine. Aimed at researchers, physicians, and students, it encourages the documentation of family medicine's history in the U.S. The grant supports travel and research expenses to enhance the oral history collection, ensuring a diverse representation of experiences and perspectives in the field.
Historical Records & Archives History Of Science

American Indian Services: Trade Scholarship

AMERICAN INDIAN SERVICES
Private
United States
Up to US $2,500
The American Indian Services: Trade Scholarship offers financial support for American Indian and Alaska Native students pursuing trade education. Since its inception over 40 years ago, the program has awarded scholarships to more than 35,000 Native students. Eligible applicants can receive up to $2500, with distinct deadlines for January and September awards. This initiative aims to empower Native students by facilitating access to trade school opportunities.
Vocational & Trade Education Native American Services

AWS Welding Workforce Grant

American Welding Society Inc
Private
United States
Up to US $50,000
The AWS Welding Workforce Grants aim to enhance welding programs by providing up to $50,000 for essential resources such as new equipment and training. This initiative addresses the growing demand for skilled welders while supporting educational institutions. Eligible applicants include secondary schools, community colleges, and post-secondary programs. Preference is given to proposals that significantly increase welding graduates and address geographic areas with high needs. Note: Applications are currently closed and will reopen in January 2026.
Workforce Preparation & Job Readiness

Andrew Burgin Charitable Trust Grant

Andrew Burgin Charitable Trust
Private
United States
US $5,000 - US $20,000
The Andrew Burgin Charitable Trust Grant supports organizations that are exempt under Section 501(c)(3) and focuses on charitable, educational, religious, and scientific purposes. With grant sizes ranging from $5,000 to $20,000 and an annual budget of approximately $55,000, the trust primarily serves Alabama organizations. Applications are accepted year-round, but must meet specific deadlines for review. This grant offers opportunities across diverse areas such as arts, education, health, and human services.
Art & Culture Humanities & Social Science Education +6 more

AWI Implementing Refinement Grant

Animal Welfare Institute
Private
Canada, United States
Up to US $8,000
The AWI Implementing Refinement Grant, offered by the Animal Welfare Institute, aims to enhance the welfare of animals in experimentation. Grants up to $8,000 support equipment purchases or staff training for implementing proven refinements. Eligible applicants must be from the U.S. or Canada, and projects should be completed within a year. The grant focuses on improving animal lives beyond basic needs, ensuring no funds are misused for indirect costs or basic care.
Animal Welfare - General

TTO Office Wide (OW) BAA 2025

US DOD: Advanced Research Projects Agency
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The DARPA Tactical Technology Office (TTO) seeks innovative proposals to enhance national security through cutting-edge technology. This initiative focuses on Design/Build/Buy, Surge and Sustain, Long Range Effects, and Disruptive Innovation. By fostering rapid adaptation and sustainable force structures, TTO aims to demonstrate revolutionary systems that are not only effective but also affordable and responsive to emerging challenges.
Domestic / Homeland Security Military Operations Data Science & Digital Information Systems +1 more

Outdoor Fund - Local Impact Grant

Bass Pro Shops & Cabelas Outdoor Fund
Private
Canada, United States
Up to US $5,000
The Outdoor Fund - Local Impact Grant supports local organizations and projects that enhance community engagement and align with conservation goals. With grants up to $5,000, eligible projects include youth fishing clinics and trail maintenance. Funded by Bass Pro Shops and Cabela’s, this initiative exemplifies their commitment to wildlife conservation and connecting communities to the outdoors. Eligible applicants include municipalities and registered nonprofits in the U.S. and Canada, focusing on specific conservation efforts.
Environmental Conservation Outdoor Equity Outdoor Recreation

Community Support - Fundraising Events and Giveaway Donations

Bass Pro Shops & Cabelas Outdoor Fund
Private
Canada, United States
Up to US $2,500 in in-kind support
Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.
Environmental Conservation Outdoor Recreation Outdoor Equity +1 more

Community Support - Missouri Ozarks Community Donations

Bass Pro Shops & Cabelas Outdoor Fund
Private
Christian County, Missouri, Greene County, Missouri +4 more
Unspecified amount
The Missouri Ozarks Community Donations, led by Bass Pro Shops, aims to strengthen local nonprofits in the Springfield and Branson areas. By supporting initiatives that enhance community well-being and conservation efforts, this program invites municipalities and registered 501(c)(3) organizations to apply for grants of any amount. This funding initiative is part of a broader commitment to advocate for sustainable outdoor practices and community empowerment in the Missouri Ozarks.
Community Services

First Responders Outreach (FRO) Grant

Gary Sinise Foundation
Private
United States
Unspecified amount
The First Responders Outreach (FRO) Grant, provided by the Gary Sinise Foundation, supports essential resources for firefighters, police, and EMTs. This grant specifically targets First Responder Departments, allowing one application per year focused on equipment and training. It excludes funding for building costs and weaponry. This initiative aims to enhance the safety and preparedness of those who protect our communities during emergencies, ensuring they have the necessary tools and training to perform their vital roles effectively.
First Responders

9.11 Promise Run Scholarships

9.11 Promise
Association/Society
United States
US $5,000 - US $15,000
The 9.11 Promise Run Scholarships provide financial support to children of first responders and military personnel who have been killed or injured. Established in 2019, these scholarships range from $5,000 to $15,000 and can be applied toward trade school or college tuition. Eligible applicants must be under 25 years old and maintain a minimum GPA of 2.0. Awards are issued directly to accredited institutions and can be renewed for up to six years, ensuring continued support for eligible students.
Academic Scholarship Programs College Success / Persistence

Thoma Foundation Special Project Funding Grant

Carl And Marilynn Thoma Foundation
Private
United States
Unspecified amount
The Carl and Marilynn Thoma Foundation offers Special Project Funding to support innovative initiatives in the arts, particularly in under-resourced areas. This grant encourages collaborative projects that enhance community engagement and education, focusing on art exhibitions and scholarships in the greater Texas Panhandle. By fostering leadership and creativity, the Foundation aims to empower individuals and organizations to make a lasting impact in the fields of art and art history.
Fine Art Visual Arts Art Education +7 more

Kathryn Cramer Early Career Research Development Award

Ao North America Inc
Private
Canada, United States
Up to US $35,000
The Kathryn Cramer Early Career Research Development Award provides essential start-up funding for orthopedic trauma surgeons in the U.S. and Canada, who have completed their fellowship within the last five years. This award aims to support innovative research projects that can be accomplished within two years, fostering professional development and collaboration among surgeons. Applicants must be members of AO Trauma and demonstrate early success in their research endeavors.
Orthopedics Medical Education & Professional Training

Henry Hanff Fellowship Award

Ao North America Inc
Private
Europe, North America
Up to US $5,900
The Henry Hanff Fellowship Award offers a unique opportunity for practicing North American trauma surgeons to enhance their skills through a short-term fellowship at a trauma clinic in North America or Europe. Sponsored by AO North America, the fellowship lasts four to eight weeks and covers airfare and a stipend for living expenses, with a total award not exceeding $5,900. Participants must submit a report on their experience for publication, enhancing professional development and collaboration.
Orthopedics Medical Education & Professional Training

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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