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Best Massachusetts Grants for Nonprofits

Find nonprofit grants in Massachusetts, including opportunities in Boston, Worcester, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.66B

Total funding

$5K

Median grant

10,000+ grants
$2.66B total
$5K median

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9,925 Results based on applied filters

Native Entities Grant Program

DOC NIST ERA
Federal Government
United States
US $500,000 - US $2,500,000
The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.
Native American Services Technology Access & Digital Literacy Indigenous Services

DoW Bone Marrow Failure, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $800,000
The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.
Skeletal Diseases Myeloma

DoW Bone Marrow Failure, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.
Skeletal Diseases Myeloma

DoW Rare Cancers Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $490,000
The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.
Cancer / Oncology

DoW Rare Cancers Resource and Community Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,120,000
The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.
Cancer / Oncology

DoW Joint Warfighter Medical, Military Medical Research and Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $1,400,000 - US $3,000,000
The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.
Military Operations

DoW Bone Marrow Failure, Resource Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,250,000
The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.
Skeletal Diseases Myeloma

DoW Kidney Cancer, Academy of Kidney Cancer Investigators – Early-Career Scholar Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The DoW Kidney Cancer Early-Career Scholar Award is a unique initiative by the Academy of Kidney Cancer Investigators, established in FY19. It aims to foster innovative kidney cancer research through a mentoring program that pairs early-career scholars with experienced mentors. This program not only enhances research capabilities but also builds a robust network of kidney cancer researchers. By supporting promising scholars, the initiative aspires to advance the field and improve treatment outcomes for kidney cancer patients.
Cancer / Oncology Kidney Diseases

DoW Parkinson’s, Investigator-Initiated Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The FY26 Parkinson’s Research Program Investigator-Initiated Research Award supports innovative, multidisciplinary research projects aimed at advancing the understanding and treatment of Parkinson’s disease. The award encourages collaboration among multiple principal investigators, requiring preliminary data and allowing clinical trials to enhance research outcomes. This initiative is vital for fostering impactful discoveries within the four specified focus areas of the program, ultimately improving patient care and management.
Parkinson’s Disease

Fiscal Year (FY) 2027 Department of the Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
United States
US $450,000 - US $525,000
The FY 2027 DoN HBCU/MI Program aims to enhance the research capabilities of Historically Black Colleges and Universities and Minority Institutions. This initiative promotes innovative solutions to naval science challenges while engaging students and faculty in STEM fields. Key objectives include strengthening research infrastructure and fostering collaborative efforts across institutions. White papers are due by September 18, 2026, and should clearly outline the proposed advancements in naval-relevant science and technology.
Engineering Education - Higher Education Science +1 more

DoW Kidney Cancer, Idea Development Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
Up to US $900,000
The FY26 Kidney Cancer Research Program's Idea Development Award supports innovative research that enhances understanding of kidney cancer, aimed at improving patient outcomes. Proposals should feature a strong hypothesis and a detailed research plan, with team members experienced in kidney cancer research. A unique aspect is the Partnering Principal Investigator option, fostering collaboration between two investigators, ensuring comprehensive project development while allowing for distinct submissions. This award emphasizes impactful partnerships to drive advancements in the field.
Cancer / Oncology Kidney Diseases

DoW Parkinson’s, Early Investigator Research Award

US DOD: U.S. Army Medical Command
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $1,000,000
The FY26 Parkinson’s Research Program (PRP) Early Investigator Research Award supports early-career researchers in Parkinson’s disease (PD) research. It offers two funding levels: Level 1 for fellows requiring a Mentor and Level 2 for independent investigators. The PI must show potential in PD research, with Level 1 emphasizing mentorship and Level 2 needing preliminary data. Research must align with one of the four FY26 PRP Focus Areas, excluding clinical trials.
Parkinson’s Disease

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

George and Viola Hoffman Award

American Association of Geographers
Association/Society
United States
Up to US $500

An award from the George and Viola Hoffman Fund may be made annually for student research toward a master’s thesis or doctoral dissertation on a geographical subject in Eastern Europe. Eastern Europe includes the countries of East Central and Southeast Europe from Poland south to Romania, Bulgaria, and the successor states of the former Yugoslavia. Topics may be historical or contemporary, systematic or regional, limited to a small area or comparative.

Geography

F26AS00104 State ANS Management Plan 2026

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
United States
US $5,000 - US $150,000
The F26AS00104 State ANS Management Plan 2026 aims to combat aquatic nuisance species through pre-proposals followed by full applications. Managed by the US Department of the Interior's Fish and Wildlife Service, this initiative requires a 25% cost-share and limits administrative costs to 5%. Applications are due by October 14, 2026, though the funding opportunity closes on December 16, 2026. The plan is crucial for maintaining biodiversity and supporting a coordinated national approach to invasive species management.
Ichthyology (Fish) Limnology Fisheries +1 more

Susan G. Komen Career Catalyst Research Grant

The Susan G Komen Breast Cancer Foundation Inc
Private
United States
Up to US $150,000

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

Breast Cancer

Readiness and Recreation Initiative (RARI) – Recurring 5 Year Notice

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $3,000,000
The Readiness and Recreation Initiative (RARI) by the National Park Service aims to enhance outdoor recreation and support compatible land uses near military installations. This program, funded through the Land and Water Conservation Fund, provides up to 50% of project costs, encouraging collaboration with the Department of War. Projects must involve land acquisition and align with national priorities to ensure public outdoor access in perpetuity, directly benefiting both military and civilian communities.
Urban Planning Outdoor Recreation Disaster Preparedness +1 more

Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026

US HUD: Office of Public and Indian Housing (PIH)
Federal Government
United States
US $500,000 - US $7,500,000
The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.
Minority Services Equitable & Affordable Housing Native American Services

Stephany June Bryan: Bold Spirit of Achievement Scholarship

Hogg Foundation for Mental Health
State/Local Government
United States
US $5,000

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Stephany June Bryan: Bold Spirit of Achievement Scholarship

The Hogg Foundation for Mental Health is offering ten $5,000 scholarships in honor of Stephany June Bryan to individuals facing personal and financial barriers to achieving their educational or career goals due to the impact of living with a mental health challenge and/or supporting a loved one with a mental health challenge.

You do not need to be enrolled in a program at the time you submit your application. However, you will need to provide enrollment verification and/or a certificate of completion when/if it is awarded.

Mental Health & Psychiatric Diseases Education - Higher Education Vocational & Trade Education +2 more

BlackRock Future Builders Grant

Blackrock Foundation Inc
Private
Puerto Rico, United States +1 more
US $500,000 - US $1,000,000

About BlackRock

We’re a global asset manager and technology provider dedicated to helping more and more people experience financial well-being. We help millions of people invest to build savings that serve them throughout their lives. The BlackRock Foundation which funds and partners with organizations that strengthen financial security for more people,

BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

  • Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
  • Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.
Workforce Preparation & Job Readiness Apprenticeship & Internship Programs Vocational & Trade Education +2 more

Medical Student Service Leadership Project Grant​​​

Alpha Omega Alpha Honor Medical Society
Private
United States
Up to US $9,000

AΩA is committed to preparing future leaders in medicine and health care. Leadership is about making a positive difference and can be developed through education, observation, experience, and by working with leader mentors. Service learning provides excellent opportunities for students to develop as servant leaders. Only one team from each school may be nominated.

Medical Education & Professional Training

National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional) (362722)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Centers for Biomedical Imaging and Bioengineering (NCBIB) provide critical resources for biomedical imaging and bioengineering research. This funding opportunity supports the development of innovative technologies tailored to the needs of basic, translational, and clinical researchers. NCBIB facilitates technology access, training, and dissemination, enhancing collaboration and advancing the field. Applications are encouraged to foster advancements that address complex biomedical challenges.
Bioengineering Biomedical Imaging

Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP) aims to strengthen viral hepatitis surveillance and prevention efforts across the United States. By enhancing outbreak response capabilities and promoting testing and treatment in high-impact settings, this initiative seeks to improve public health outcomes. Key components include partnerships, strategic planning, and perinatal hepatitis C programs, ultimately striving for better access to prevention and treatment services, aligning with CDC priorities.
Liver Disease Hepatitis B

Evelyn Manning Potter and Vivian Grove Strunk Memorial Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Evelyn Manning Potter and Vivian Grove Strunk Memorial Scholarship, administered by the Community Foundation of Washington County, MD, supports students pursuing careers in the administrative professional field. Established in memory of two dedicated professionals, this scholarship aims to provide financial assistance to qualified individuals, promoting their educational and career aspirations. The foundation offers over 100 scholarships, reflecting its commitment to enhancing the community's quality of life and supporting local talent.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Carol D. Garling Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Carol D. Garling Scholarship, established by Carol D. Garling, provides financial assistance to students pursuing a post-secondary education who have completed at least 30 credit hours at an accredited institution. Offered by the Community Foundation of Washington County, MD, this scholarship is part of a larger initiative to support local students and promote educational advancement within the community. Applications are accepted annually from January to April 1st, encouraging both high school graduates and non-traditional students.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Bill Dorsey Memorial Scholarship Fund for Barbara Ingram School for the Arts

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Bill Dorsey Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, offers scholarships to students at the Barbara Ingram School for the Arts (BISFA). Designed for rising sophomores, juniors, and seniors, this fund helps cover costs related to their arts discipline. Applications are available in the Fall, supporting the foundation's mission to enhance educational opportunities for local students and nurture their artistic talents.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Hagerstown Garden Club Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Hagerstown Garden Club Scholarship, administered by the Community Foundation of Washington County, supports Washington County residents pursuing education in horticulture. Eligible applicants include graduating high school seniors and current college students with a minimum GPA of 3.0. This scholarship honors the legacy of the Hagerstown Garden Club and is part of a broader initiative to enhance community life through educational opportunities, fostering both personal and professional growth in the horticultural field.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +2 more

Massachusetts Grants for Nonprofits Highlights

Massachusetts grants for nonprofits provide funding to support innovation in education, technology, and public health. The following grants help organizations tackle challenges, promote sustainability, and enhance quality of life for communities across the state.


Search Instrumentl's Massachusetts Grants Database


Find 241 funding opportunities for nonprofits in Massachusetts, with $67.8M available. Instrumentl provides nonprofits with deadline management tools, customized grant searches, and strategic insights to support impactful projects across the state.

Grant Insights : Massachusetts Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Massachusetts grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

95 Massachusetts grants for nonprofits over $25K in average grant size

75 Massachusetts grants for nonprofits over $50K in average grant size

60 Massachusetts grants for nonprofits supporting general operating expenses

200+ Massachusetts grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Massachusetts grants for Nonprofits?

Most grants are due in the first quarter.

Q1
32.0%
Q2
24.4%
Q3
18.8%
Q4
24.8%

Typical Funding Amounts

What's the typical grant amount funded for Massachusetts Grants for Nonprofits?

Grants are most commonly $26,875.

$250 $250 Min.
$26,875 $26.9 K Median
$413,560 $413.6 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

According to data from the IRS, funding for nonprofits in Massachusetts increased drastically from 2021 to 2022. The 20.67% increase saw funding amounts jump from $11.7B in 2021 to $14.1B in 2022. The most common grant focus areas in Massachusetts during this time were professional societies, associations, research institutes and/or public policy analysis, and alliance/advocacy organizations. Suffolk County, Middlesex County, and Norfolk County received the most funding across the state.

Instrumentl is the only complete grant solution that allows nonprofits to discover opportunities, cultivate relationships, apply for grants, streamline the application process, and report on grant management.

Learn more about how to find grants for your nonprofit.

When applying for funding, nonprofits in Massachusetts should be aware that of the available grants, 32.0% are due in Q1, while 24.8% are due in Q4. Fewer application deadlines fall in Q2 and Q3 as 24.4% and 18.8%, respectively, are due during these periods.

There are more than 200+ grants with a total of $67,823,884 in funding available to Massachusetts nonprofits. These grants, which have a median funding amount of $26,875, support organizations that address everyday challenges, promote sustainability, and enhance the quality of life for communities across the state.

The majority of grants available to Massachusetts nonprofits are funded by private organizations. State and local governments and corporations also provide funding for grants.

  • Private Organizations: Private organizations provide 124 grant opportunities that support causes such as environmental conservation, sustainability, and health and medicine.
  • State and Local Government: State and local government agencies support 72 grants and provide funding for agriculture, museums and cultural institutions, and homeland security.
  • Corporations: Corporations fund 22 grants for Massachusetts nonprofits that support homelessness services, entrepreneurship, affordable housing, and more.
    • Be sure to review all grant application requirements and deadlines to improve your chances of securing funding.

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