Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.
10,000+
Available grants
$2.60B
Total funding
$5K
Median grant
Skip the search. Get matched with grants that fit your non-profit.
Smart recommendations based on your profile — in minutes.
About Boeing
A leading global aerospace company and top U.S. exporter, Boeing develops, manufactures and services commercial airplanes, defense products and space systems for customers in more than 150 countries. Our U.S. and global workforce and supplier base drive innovation, economic opportunity, sustainability and community impact. Boeing is committed to fostering a culture based on our core values of safety, quality and integrity.
The Employees Community Fund (ECF) of The Boeing Company
One of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has empowered employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites provide combined employee donations to nonprofits in their communities through ECF grants.
Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.
Puget Sound Chapter
The Employees Community Fund (ECF) of Boeing Puget Sound is a pooled fund consisting of recurring payroll contributions from generous Boeing employees. It funds local nonprofits that help thousands of families and individuals in the Puget Sound region where Boeing employees live and work.
ECF focus areas
ECF makes grants to 501(c)(3) Health & Human Service nonprofits such as food banks, job-training programs, shelters, transitional housing, mental health services, and low-income medical clinics. ECF seeks the direct client benefit of each grant to ensure that our employees’ contributions directly help those in need.
ECF funding criteria
ECF has two distinct grant categories – Supporting Grants and Capital Campaign Grants.
ECF of Boeing Company: Puget Sound Chapter Supporting Grants
Consideration is given to nonprofits/agencies that are performing well and are seeking to upgrade, replace or modify elements of their infrastructure.
Presser Foundation
Passionate about music, Theodore Presser wanted to give back to it. When he died in 1925, he had been widowed twice without any children. The bulk of his fortune was left to The Presser Foundation, which was formally established 14 years after his death. From 1995 to June 2021, The Presser Foundation gave more than $80 million to music organizations, undergraduate and graduate music students, and retired music teachers.
Originally, the Foundation sought to promote the causes of musical education and musical philanthropy by providing scholarships for promising students, supporting the construction of buildings for music organizations, and directing aid to retired music teachers. Over time, the Foundation has evolved to support a broad array of music genres, expand its grantmaking areas, convene its nonprofit partners at special events, and collaborate with fellow funders, while continuing to follow the original intent and wishes of Theodore Presser.
Assistance to Music Teachers
Theodore Presser, mindful of his own early struggles in the profession, was committed to the support of music teachers. He also felt a sense of gratitude for the thousands of teachers who were the primary customers of his music publication business. In 1906, he established the Presser Home for Retired Music Teachers in Philadelphia. When it was no longer practical to maintain an independent facility, the Foundation created the Assistance to Music Teachers Committee to carry on its basic mission of financial support for retired teachers with financial need.
Typically, the Foundation provides modest financial assistance and/or help with the cost of medical insurance. Awards are made to individuals living in the United States whose primary occupation was as a teacher of music. To be considered for Assistance, applicants must be nominated by a music institution for consideration.
The Kelley Foundation
The Kelley Foundation was established by Robert and Judy Kelley and their daughter Marla. The Kelleys are native Oklahomans and longtime residents of Southern Oklahoma.
The foundation is primarily focused on humanitarian projects in Oklahoma, with an emphasis on Southern Oklahoma. Our mission is to develop and strengthen our community, state, and nation by providing essential resources to those in need.
The Kelley Foundation Grant
The Kelley Foundation is a private, charitable foundation, incorporated under the laws of the State of Oklahoma and operated exclusively for providing support through its gifts and grants to religious, charitable, scientific, and educational institutions which are qualified under section 501(c)(3) and which are not private foundations within the meaning of section 509(a) of the Internal Revenue Service Code.
About RWJF
At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.
Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions
RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.
Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.
Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system.
About American-Scandinavian Foundation (ASF)The American-Scandinavian Foundation (ASF) promotes firsthand exchange of intellectual and creative influence between the United States and the Nordic countries: Denmark, Finland, Iceland, Norway, and Sweden. ASF offers fellowships, cultural grants, internships/training, publications, exhibitions and other public programs reinforcing the strong relationships between the two regions, honoring their shared values, and appreciating their differences.ASF Public Projects GrantThe American-Scandinavian Foundation promotes the cultures of the Nordic countries in the United States and American culture in the Nordic countries by encouraging programs that will enhance public appreciation of culture, art, and thought. In establishing priorities, the Foundation considers the lasting benefits that may be achieved by any grant and favors projects where its contribution will complement support from other sources.
About Pfizer Grants
Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.
Interventional Research Studies of Brentuximab Vedotin-Based Novel Combinations in AITL and PTCL-NOS
This competitive program is designed to support interventional InvestigatorSponsored Research aimed at generatin clinical evidence for brentuximab vedotin in novel combination approaches in angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma–not otherwise specified (PTCL-NOS).
Project Types and Area of Interest
Studies considered for Pfizer support should address key clinical and scientific gaps in the use of brentuximab vedotin in AITL and PTCL-NOS irrrespective of CD30 expression, with a focus on evaluating the safety and efficacy of novel brentuximab vedotin–based combinations with therapies available for PTCL treatment that are supported by a clear scientific rationale grounded in mechanism of action and/or disease biology.
About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.
About Grants to Provide Stability (GPS) ProgramThe Disabled Veterans National Foundation’s GPS (Grants to Provide Stability) Program is a grant program for veterans who find themselves in temporary financial setback. DVNF will provide up to $1,000 (not guaranteed) to help eligible veterans pay for rent or mortgage and essential utilities such as water or electricity. Applications are open on a monthly basis. Please note that each veteran can only be approved once per fiscal year (October – September).
About Disabled Veterans National FoundationThe Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability. The Disabled Veterans National Foundation (DVNF) provides critically needed support to disabled and at-risk veterans who leave the military wounded—physically or psychologically—after defending our safety and freedom.About Comfort Kits and Grab N' Go ProgramIn addition to our direct outreach, the DVNF also supports like-minded organizations that share our commitment to serving veterans. Approved organizations can apply to receive Comfort Kits for distribution to veterans in their communities. These kits are designed to meet the unique needs of veterans and offer critical support where they are needed most.
Quality Improvement Grant Request for Proposals
Optimizing Maternal RSV Immunization Delivery: A Systems-Based Quality Improvement Initiative to Improve Uptake, Equity, and Newborn Outcomes
Pfizer, in collaboration with the Society for Maternal-Fetal Medicine (SMFM), is pleased to announce a competitive grant opportunity to support independent Quality Improvement (QI) initiatives focused on advancing maternal immunization, with a specific emphasis on Respiratory Syncytial Virus (RSV) vaccination during pregnancy.
This initiative builds upon insights generated from the Maternal Immunization Needs Assessment (MINA) project, a multi-stakeholder collaboration that identified persistent clinical, behavioral, and system-level gaps in the delivery and uptake of maternal vaccines.
We seek to fund projects that implement measurable, evidence-based interventions to improve real-world delivery of maternal RSV immunization across healthcare systems and care settings. Proposed initiatives should aim to optimize access, strengthen provider–patient communication training and tools, enhance care coordination, and address structural and behavioral barriers impacting vaccine uptake and equity.
Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies. Pfizer’s GMG competitive grant program involves a publicly posted Request for Proposal (RFP) that provides detail regarding a specific area of interest, sets timelines for review and approval, and uses an expert review panel (ERP) to make final grant decisions. Organizations are invited to submit an application addressing the specific gaps in clinical practice or care as outlined in the specific RFP.
For all QI grants, the applicant (and ultimately the grantee) will be solely responsible for the design, implementation, and conduct of the proposed initiative. Pfizer will have no involvement in project development, execution, or outcomes.
About the ASHFoundation
ASHFoundation supports innovators and sparks innovation in communication sciences. We give early support to promising students, researchers, and clinicians exploring bold ideas to transform the field and improve people's lives.
Frank R. Kleffner Lifetime Clinical Career Award
The Frank R. Kleffner Lifetime Clinical Career Award recognizes an individual’s outstanding contributions to communication sciences and disorders over a period of at least 20 years. The lifetime contribution may have been in clinical service, supervision or administration of clinical service, clinical research, or any other activity that has promoted clinical excellence.
The award is given in honor of Frank R. Kleffner, a former ASHFoundation president and former ASHA president, who worked tirelessly over his lifetime until his passing in 2015 to professionalize and expand the ASHFoundation’s charitable goals.
The awardee receives a commemorative art object with a recognition plaque.
Purpose
This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.
Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity.
RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.
Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.
Total Awards
Disabled Veterans National Foundation
The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.
Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.
Homeless To Housing Program - Financial Assistance
DVNF is dedicated to assisting disabled and at-risk veterans in their transition from homelessness to permanent housing. Recognizing that securing a home is a significant milestone, DVNF understands that true stability is achieved when a house becomes a home, furnished with essential items that provide comfort and functionality. We help cover essential costs related to securing and creating comfortable housing for at-risk veterans.
The H2H Program offers comprehensive support to veterans by providing: Financial Assistance of up to $2,000 to cover essential costs related to securing permanent housing, such as security deposits and initial rent payments.
For Financial Assistance: Payments are processed through two payment cycles each month, around the 15th and 30th. If your payment is delayed beyond the expected date, a Promissory Note of Payment will be issued to the vendor, confirming our organization's responsibility and requesting that no penalties be applied to the applicant.
Better Food Policy Fund
Since its inception, the Better Food Policy Fund has set its strategic direction in a participatory fashion. We are intentionally building capacity for engagement to ensure the Fund aligns with the needs of food policy council stakeholders.
Thus far, the Fund has engaged 300+ food policy council stakeholders to help co-develop the Fund. We are immensely grateful for the individuals who helped shape the initial direction of this fund. We view this growing stakeholder audience as the people to whom the Fund’s governing body, the Independent Advisory Committee, is ultimately accountable.
Grantmaking
The Better Food Policy Fund invests in US-based food policy councils, empowering community and government collaboration for progressive food policy. We utilize participatory processes to enhance equity and redistribute power in the funding landscape. We seek to celebrate and uplift the work of food policy councils, and believe every food policy council is worthy of financial support.
We define “food policy councils” as councils, networks, coalitions, or other groups working across boundaries at the tribal, municipal, county, state, or regional level.
We support actions aimed at ensuring an enabling environment for policy change, such as:
We define “better food policy” as practices, procedures, ordinances, laws, etc. of governing institutions which strengthen community-based food systems.
We define “civic collaboration” as people joining together at the intersection of community and government to address public issues.
Wind Creek Hospitality Community Support
Our communities are like family. That’s why Wind Creek is dedicated to giving back and helping others thrive in the places we call home (and beyond). We’re always looking for creative ways to lift up our neighborhoods and make life better for us all.
Sponsorships, Donations and Giveaways
Wind Creek Hospitality Community Relations actively builds partnerships with service organizations, non-profits, educational organizations and more. If you’d like to partner with us, please submit an application at least 90 days before your event or donation is needed.
About Us
Children’s Cancer Research Fund is a national nonprofit dedicated to ending childhood cancer. Our main focus is to support the research of bright scientists across the country whose ideas can make the greatest impact for children fighting cancer. We also fund resources and programs that help kids and families as they navigate the difficult experience of cancer treatment and survivorship.
Since 1981, we’ve contributed over $235 million to research, support programs for children and families, and awareness and education outreach. In 2024, over 81 percent of funds raised went directly to these program services areas.
Children’s Cancer Research Fund (CCRF) is a national nonprofit committed to finding safer, more effective therapies for kids battling cancer. Thanks to donors and partners around the country, we have contributed over $235 million to research, education and awareness, and quality-of-life programs for childhood cancer families. We believe kids deserve safer, less toxic treatments, and we’re committed to funding groundbreaking research and services that enhance healing and care.
In 2026, Children’s Cancer Research Fund will focus our research funding efforts on three main areas:
Accelerating Hope: Clinical Trials for Hard-to-Treat Cancers Award
This funding opportunity is limited to support for clinical trials focused on hard-to-treat cancers, prioritizing Phase 0 – Phase 2 studies. Learn more about eligibility criteria and other key details below.
Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.
Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.
How common are grants in this category?
Common — grants in this category appear regularly across funding sources.
Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Missouri Grants for Nonprofits?
Grants are most commonly $13,750.
Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.
Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:
While government grants provide large awards, keep in mind that they require substantial compliance.
To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.
Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.
Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.
If you are interested in finding foundation grants, see how Instrumentl can help.