Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.
10,000+
Available grants
$2.60B
Total funding
$5K
Median grant
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Spencer Educational Foundation Inc
The Spencer Educational Foundation was founded by the Rims Atlanta Chapter in 1979. To this day, Spencer remains the premier organization funding the education of tomorrow's risk management and insurance leaders.
The Spencer Educational Foundation: awards merit-based scholarships and grants to university students pursuing careers in risk management, insurance, and/or actuarial science; provides grants that create experiential learning opportunities both on and off campus; funds the development of risk management and insurance curricula in colleges and universities; supports Risk Managers by creating internship opportunities within the risk management function of their companies; and operates across the United States and Canada.
Spencer Educational Foundation: Course Development Grants
Since 2014, Spencer has invested over $1.6 million in developing risk management and insurance (RMI) courses at close to 70 colleges and universities, exposing approximately 19,000 students to the RMI industry.
Our Course Development Grant program supports Introductory Risk Management and Insurance Course Development - for universities that have not previously offered any such instruction - as well as proposals for additional Course Curriculum Development and Program Development - for universities looking to develop a RMI program and/or expand existing RMI course offerings, with an emphasis on new and emerging areas in the industry.
American Psychiatric Association Foundation
There is no health without mental health. The APA Foundation is working in your community to provide the support and resources we all need to prioritize mental wellbeing where you live, learn, work, worship, and play.
Backed by the medical expertise of the APA and industry-leading strategic partners, we administer community-changing programs, public education campaigns, grants, and awards aimed at increasing mental health literacy, connecting individuals to needed care, and shifting attitudes toward mental health.
Edwin Valdiserri Correctional Public Psychiatry Fellowship
The Edwin V. Valdiserri Correctional Public Psychiatry Fellowship program has been made possible by a generous gift from Ronald Valdiserri, M.D., M.P.H., in memory of his brother Edwin V. Valdiserri, M.D. and creates a special opportunity for current residents who are interested in public, community, or forensic psychiatry programs to receive additional experience, training and mentorship in a correctional setting.
Program Benefits
Program Expectations
American Headache Society
The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.
Headache & Migraine Competitive Grant Program
The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care.
Adult Population RFP (Quality Improvement Solutions for the Diagnosis and Management of Migraine and Headache Disorder)
Seeking projects that drive meaningful impact in headache care through advancements in safety, clinical effectiveness, timely diagnosis, and equitable, patient-centered treatment. Submissions should feature bold, practical solutions in primary care and non-headache specialty settings, supporting adult populations with scalable, real-world innovations.
QBE Foundation Inc.
The QBE Foundation’s focus is on creating strong, resilient and inclusive communities. We work in partnership with community organizations, working in climate resilience and inclusion – two areas where we believe we can have the greatest impact.
The QBE Foundation is one component that reflects our company’s focus, involvement, and investment in the neighborhoods where we do business, and where our employees live and work. The QBE Foundation also empowers our employees to volunteer with colleagues and community partners to make a difference for those in need. Employees can also coordinate fundraisers that are matched by the foundation.
QBE Foundation Local Grant Program
This program supports high-impact, community-based initiatives aligned to our focus on climate resilience and inclusion.
Multiple grants of $30,000 will be awarded across our two focus areas.
American Headache Society
The American Headache Society (AHS) is a professional society of healthcare providers dedicated to the study and treatment of headache and face pain. The Mission of the AHS is to improve the lives of people impacted by migraine and other headache disorders. AHS advocates for those impacted by headache and the headache field, to meet our core objectives. AHS provides educational courses, scientific meetings, a journal, research support, career development opportunities, Special Interest Groups, advocacy training, and a professional community. The AHS strives to meet its objectives while fostering an inclusive sense of belonging and community.
Headache & Migraine Competitive Grant Program
The Headache & Migraine Competitive Grant Program stands at the forefront of advancing headache medicine by funding groundbreaking quality improvement initiatives. This highly competitive grant program, offered through the collaboration between the American Headache Society and Pfizer, supports projects that have the potential to reshape the field by creating widely applicable tools and driving measurable improvements in patient care.
Migraine & Women's Health
Migraine is a prevalent and debilitating neurological disease that disproportionately affects women, impacting quality of life, productivity, and overall health. Recognizing the need for innovative solutions and enhanced care, Pfizer and the American Headache Society (AHS) are collaborating to offer a new grant opportunity inviting proposals for collaborative quality improvement and research projects focused on migraine and women's health.
About Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Who we are and our impact
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Multiple sclerosis (MS) health equity
Help with healthcare costs for multiple sclerosis (health equity)
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code.
About the disease
Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.
About Patient Advocate Foundation
Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.
Who we are and our impact
Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Help with healthcare costs for Paroxysmal Nocturnal Hemoglobinuria (PNH)
This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.
About the disease
Paroxysmal Nocturnal Hemoglobinuria (PNH), also known as Marchiafava– Micheli syndrome, is a rare disease that is characterized by impaired bone marrow function and destruction of red blood cells. PNH is a rare disease that affects the circulatory system.
The Richard L and Freda K Flerlage Foundation
Our Mission
Working to empower underserved populations through small grants in support of literacy, healthcare, reduction of poverty, and the promotion of social and environmental justice.
We are a small family foundation, when possible we aim to support organizations with relatively small operating funds where our small grants will have their greatest possible impact.
Our average grant is $3,800.
Our Mission
UNCF envisions a nation where all Americans have equal access to a college education that prepares them for rich intellectual lives, competitive and fulfilling careers, engaged citizenship and service to our nation.
UNCF’s mission is to build a robust and nationally-recognized pipeline of under-represented students who, because of UNCF support, become highly-qualified college graduates and to ensure that our network of member institutions is a respected model of best practice in moving students to and through college.
UNCF’s North Star is to increase the total annual number of African American college graduates by focusing on activities that ensure more students are college-ready, enroll in college and persist to graduation. This is done through a three-pillar strategy. Positioning member institutions as a viable college option for students and investing in institutional capacity to improve student outcomes; creating transformational support programs to ensure students are enrolling and persisting through college completion; building awareness of educational attainment and cultivating college-going behaviors within the African American community.
About the UNCF Lighted Pathways Program
Increasing the number of Black investment management professionals one opportunity at a time
According to The American College and the CFP Board, African Americans only make up 5% of financial advisors and 2% of certified financial planners (CFP), even though African Americans represent 13.4% of the U.S. population.
The UNCF Lighted Pathways programs meets the disparity and lack of Black talent in asset management through the UNCF Lighted Pathways initiative which provides scholarships and internships to African American undergraduate students interested in the investment management industry. Through this initiative, UNCF Lighted Pathways aims to create a career pathway to attract, develop, and retain Black talent for the asset management industry.
The UNCF Lighted Pathways Program excites, educates, and empowers young people by supporting personal and professional development, driving company performance, and providing the asset management industry the talent they need to meet today’s challenges and tomorrow’s opportunities. This program offers students a glimpse inside the dynamic, global asset management industries and the career opportunities, potential and rewards within them.
Students are afforded the opportunity to receive $5,000 in scholarships and/or participate in internships in the financial industry provided by the program’s partners.
JFS–David Rubenstein Memorial Scholarship
The JFS–David Rubenstein Memorial Scholarship, established by Dr. Robert Rubenstein and Marie Raftery, honors the memory of Dr. Robert’s son, David. The program provides financial support to students from San Diego’s Jewish community pursuing college or vocational education, and encourages them to cultivate intellectual curiosity, reflect on Jewish values, and give back to their community.
Scholarships of up to $10,000 will be awarded based on academic achievement, community involvement, and financial need.
Students are eligible to receive up to a total of four (4) years of JFS-David Rubenstein Memorial Scholarship funding, and the funding years do not have to be consecutive. Scholarships are made on a year-to-year basis and are not automatically renewed. Scholarship recipients must submit a new application and the required documentation in compliance with the application deadlines, stated herein, for each year that they seek funding.
Scholarship funds will be sent directly to the academic institution the student is attending solely for use toward qualifying academic expenses, including tuition, school-provided housing, books, school fees, or required academic supplies/equipment. Should the recipient not matriculate college by the date listed in the award, he or she agrees to forfeit the scholarship award.
Neuroscience & Society Grants
Applicants may request up to $150,000 in funding for projects over a period of up to 18 months.
Neuroscience and society is the interdisciplinary study of how neuroscience informs and reflects society, and practical work to put these ideas into action. Neuroscience and society includes fields where neuroscience interfaces with the world, such as ethics, law, humanities, medicine, arts, social sciences, policy, education, journalism, and public engagement. This list is meant to be illustrative, not exhaustive. Other disciplines may fall within the purview of neuroscience and society.
While neuroscience and society is not the same as neuroethics, bioethics, or science and technology studies, there are areas of overlap.
Another way we think about it: Neuroscience & society is a paradigm for how we can teach neuroscience to people, train people to do societally relevant neuroscience-focused work, and engage diverse communities of people to shepherd the development and application of neuroscience.
Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.
Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.
How common are grants in this category?
Common — grants in this category appear regularly across funding sources.
Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Missouri Grants for Nonprofits?
Grants are most commonly $13,750.
Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.
Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:
While government grants provide large awards, keep in mind that they require substantial compliance.
To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.
Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.
Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.
If you are interested in finding foundation grants, see how Instrumentl can help.