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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,702 Results based on applied filters

Campership Grant

Colburn-Keenan Foundation
Private
United States
Up to US $500
The Campership Grant, offered by the Colburn-Keenan Foundation, aims to support children affected by chronic inherited bleeding disorders by providing up to $500 for camp attendance. This initiative is designed to help families send their children to specialized camps, fostering community and support. Eligible applicants include children under 18 with chronic illnesses and those whose siblings or parents are affected. The program emphasizes the importance of community engagement and aims to alleviate financial burdens for families.
Summer Camps

Camp Equipment & Capital Improvement Grant Program

Colburn-Keenan Foundation
Private
United States
Unspecified amount
The Camp Equipment & Capital Improvement Grant Program, established by the Colburn-Keenan Foundation, aims to enhance the experiences of children with chronic inherited bleeding disorders. This initiative provides funding to camps for acquiring new equipment or improving facilities, emphasizing the importance of a supportive environment for these children. Eligible camps must serve at least 25% of participants affected by such disorders, ensuring that the assistance directly impacts those in need.
Summer Camps

Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
US $2,500,000
The National Institutes of Health is launching a funding opportunity to explore the mechanisms of skin injuries caused by toxic chemicals. This initiative aims to understand the common pathways of injury from various harmful substances, facilitating the discovery of therapeutic targets. Researchers are encouraged to collaborate and apply their expertise in cutaneous wound healing. The goal is to develop broad-spectrum medical countermeasures for mass casualty events involving toxic exposures, enhancing public health safety.
Cell Biology Environmental Chemistry & Toxicology Wounds & Injuries +1 more

Maximizing Investigators' Research Award

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.
Biology Biochemistry Medical Education & Professional Training

Peter Chortek Leadership Award

Jewish Community Foundation Of San Diego
Private
United States
Up to US $9,540
The Peter Chortek Leadership Award honors Jewish high school students in San Diego who demonstrate outstanding leadership and commitment to community service through tikkun olam. Awardees receive a $9,000 stipend, $540 to set up a Donor Advised Fund, and a professional video showcasing their project. This award encourages students to create or enhance community initiatives, fostering engagement in social justice and service projects.
Community Development & Revitalization

Delta Scholarship

Jewish Community Foundation Of San Diego
Private
United States
Up to US $40,000
The Delta Scholarship aims to support college-bound minority students in San Diego County who are dedicated to pursuing higher education. Established in memory of Jim Lewis, a passionate community leader, this scholarship offers up to $10,000 per student annually for four years, based on financial need. Eligible applicants must be graduating high school seniors with a minimum GPA of 3.0, planning to attend an accredited college or university.
Education - Higher Education Career / College Preparation Academic Scholarship Programs

College Now Greater Cleveland Manufacturing Scholarship

College Now Greater Cleveland
Association/Society
United States
Up to US $2,000
The College Now Greater Cleveland Manufacturing Scholarship offers financial assistance to high school graduates pursuing training in manufacturing. Awarded funds, up to $2000, are sent directly to educational institutions for related expenses. Applicants must reside in specific Ohio counties and be enrolled in eligible programs. This scholarship aims to support individuals seeking vocational training, certifications, or degrees within a two-year timeframe, fostering career development in the manufacturing sector.
Vocational & Trade Education

Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NHLBI is set to release a NOFO aimed at enhancing an international research platform for cardiac surgery. This initiative will integrate various research areas, including mechanistic science and implementation science, to advance innovative techniques and improve health outcomes for adults with cardiovascular disease. Furthermore, the platform will serve to train future clinical trialists. Potential applicants are encouraged to start forming collaborations and preparing their proposals, as applications are not yet being solicited.
Bioengineering Pharmacology Cardiovascular Diseases & Systems +1 more

Forecast to Publish a Notice of Funding Opportunity for Paul Calabresi Career Development Award in Clinical Oncology (K12 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Cancer Institute (NCI) plans to issue a Notice of Funding Opportunity (NOFO) for the Paul Calabresi Career Development Award in Clinical Oncology (K12). This program aims to enhance training for clinician-scientists in cancer research, fostering their career development and collaboration with basic research scientists. It mandates diverse oncology specialties in faculty, individualized career development plans, and mentorship, supporting Scholars for up to three years to promote their research initiatives in clinical trials.
Cancer / Oncology Biotechnology Health Policy & Advocacy +1 more

EA Funds : EA Infrastructure Fund Grant

Centre For Effective Altruism Usa Inc
Private
Countries
US $10,000 - US $300,000
The EA Infrastructure Fund Grant supports projects that enhance effective altruism by improving access to talent, capital, and knowledge. With grants typically ranging from $5,000 to $200,000, it welcomes applications from individuals, nonprofits, and academic institutions worldwide. However, individuals must ensure their projects conclude by August 31, 2025. The fund aims to amplify the impact of direct charitable work and foster a community committed to effective altruism principles.
Volunteerism & Philanthropy Nonprofit Growth & Development Community Services +1 more

EA Funds: Animal Welfare Fund Grant

Centre For Effective Altruism Usa Inc
Private
Countries
Up to US $200,000
The EA Funds: Animal Welfare Fund Grant aims to enhance the welfare of nonhuman animals globally through strategic grants. It focuses on neglected regions, innovative research, and impactful advocacy, particularly for farmed and wild animals. The fund supports projects that alleviate suffering, promote alternatives to factory farming, and engage in policy advocacy. By contributing to this grant, you can help create a significant positive impact on animal welfare and support initiatives that are often overlooked.
Animal Welfare - General Animal Welfare - Domestic Animals & Pets Farms & Farming +2 more

William C. Risser Charitable Trust Grants

William C Risser Irrev Trust 1865-4019875730
Private
United States
US $25,000 - US $55,000
The William C. Risser Charitable Trust Grants support mental health research, particularly in Schizophrenia. This private foundation assists 501(c)(3) nonprofit organizations across the U.S. with grants typically ranging from $25,000 to $55,000. Administered by Wells Fargo, the Trust awards 1-2 grants annually, focusing on program support for scientific and educational research. Eligible organizations must meet IRS exemption requirements.
Schizophrenia

Age-Friendly Health Systems Cohort Scholarships for the AHA Next Generation Leaders Fellowship

John A Hartford Foundation
Private
United States
US $13,995
The John A. Hartford Foundation offers scholarships for the Age-Friendly Health Systems Cohort as part of the AHA Next Generation Leaders Fellowship. This initiative targets healthcare leaders aiming to implement the 4Ms Framework, enhancing care for older adults. Selected fellows will receive a program fee scholarship of $13,995, enabling them to focus on transformation efforts in health systems. This fellowship seeks diverse leaders to address critical healthcare challenges and improve quality, safety, and affordability.
Senior Services Aging / Gerontology Patient Care & Services +5 more

Anna B. Glauser Trust Grants

Anna B Glauser Trust Will Nect
Private
United States
US $2,500 - US $5,000
The Anna B. Glauser Trust Grants provide financial support to organizations aiding physically handicapped individuals, particularly blind residents in Delaware County, PA. Established in memory of Willis K. Glauser, the trust awards 1-2 grants annually, ranging from $2,500 to $5,000. Eligible organizations must be 501(c)(3) certified, while funding for salaries is typically excluded. This initiative reflects Anna Glauser's lifelong commitment to assisting the visually impaired community.
Vision Impairment Care & Services Physical Disabilities

Local Shelter/Agency Support Grant

Ms Molly Foundation
Private
United States
Unspecified amount
The Ms. Molly Foundation provides essential support for domestic violence victims through the Local Shelter/Agency Support Grant. Established in 1996, the foundation aims to raise awareness and assist local agencies committed to helping victims find safety and empowerment. Eligible applicants include 501(c)(3) nonprofit shelters that partner with Molly Maid franchises. By addressing the cycle of violence, the foundation strives to create healthier family environments and restore hope to those affected.
Domestic Violence

The Andy Warhol Foundation- Arts Writers Grant

Andy Warhol Foundation for the Visual Arts
Private
United States
US $15,000 - US $50,000
The Andy Warhol Foundation's Arts Writers Grant supports writers engaging with contemporary visual art through various formats, including articles, books, and short-form writing. Grants range from $15,000 to $50,000, catering to both emerging and established writers. Eligible applicants must be individuals over 25, U.S. citizens or residents, and published authors. This initiative encourages critical discourse and interdisciplinary approaches in arts writing, particularly related to post-World War II visual art and its diverse contexts.
Performing Arts Visual Arts Art History

Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund Grant

Karl A Bickel Charitable Trust
Private
United States
Approximately US $40,000
The Karl A. Bickel and Madira Bickel Journalistic Scholarship Fund Grant supports journalism students at accredited colleges and universities. Established under Karl A. Bickel's Last Will and Testament, it awards approximately $40,000 annually. Eligible organizations must have journalism programs and qualify as 501(c)(3) exempt entities. While there are no geographical restrictions, preference is given to institutions in Florida. The fund is administered by Wells Fargo Bank, ensuring that deserving students receive necessary financial support.
Education - Higher Education Journalism Academic Scholarship Programs

MG Eugene C. Renzi, USA (Ret.) STEM Teachers Scholarship

AFCEA
Association/Society
United States
US $2,500
The MG Eugene C. Renzi, USA (Ret.) STEM Teachers Scholarship, funded by AFCEA and ManTech International, offers $2,500 annually to support U.S. citizens or permanent residents pursuing graduate-level education in STEM teaching for grades K-12. This scholarship honors the legacy of Maj. Gen. Renzi and is aimed at candidates with a minimum GPA of 3.5 who are enrolled in accredited programs. It covers tuition and course-related expenses, fostering future educators in critical STEM fields.
Education - Higher Education Teacher Development & Training STEM / STEAM Education

Notice of Intent to Publish a Funding Opportunity Announcement for HIV Pediatric, Adolescent and Maternal Clinical Trials

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $30,000,000
The US Dept. of Health & Human Services, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is set to announce a funding opportunity focused on HIV research for pediatric and maternal populations. This initiative aims to foster innovative clinical trials addressing critical research areas in HIV, inviting collaborations from experts in various fields. Applications are not currently solicited, but potential applicants are encouraged to prepare for this opportunity.
Infectious & Parasitic Diseases HIV / AIDS Chronic Illnesses

MCSF- Career & Technical Education Scholarship

Marine Corps Scholarship Foundation
Private
United States
US $2,500 - US $10,000
The MCSF Career & Technical Education Scholarship supports children of Marines pursuing non-degree certificate programs. It offers financial assistance to eligible applicants based on need, helping cover tuition, fees, and associated educational costs. With a minimum GPA requirement of 2.00 and a family income cap of $123,000, this scholarship ensures that all qualifying students have access to vocational training at accredited institutions. Applications are accepted year-round, providing flexibility for students.
Workforce Preparation & Job Readiness Vocational & Trade Education

Earth Rising Foundation Grants

Earth Rising Foundation
Private
United States
US $200 - US $20,000
The Earth Rising Foundation Grants provide financial support ranging from $200 to $20,000 for grassroots climate initiatives. The foundation emphasizes empowering Indigenous communities, advocating for sustainable agricultural practices, and addressing social justice issues linked to climate change. By fostering youth involvement and supporting innovative projects, the foundation aims to create a vision for a sustainable future that respects both people and the planet. Applications must be submitted through a US-based nonprofit organization.
Youth Services Climate Change Resilience & Equity Diversity, Equity & Inclusion +3 more

Sensata Foundation Grant

Sensata Technologies Foundation Inc
Private
United States
US $5,000 - US $25,000
The Sensata Foundation, established in 2017, is a 501(c)(3) nonprofit supporting community development and STEM education across the U.S. With a focus on improving access to STEM resources and empowering youth, the Foundation partners with nonprofits to address food insecurity, homelessness, and environmental sustainability. By fostering community partnerships and providing financial support, Sensata Foundation aims to inspire future leaders and enhance the quality of life for all, particularly in underserved areas.
Homelessness Services Environment Food Security +3 more

David Kelby Johnson Memorial Foundation Grants

David Kelby Johnson Memorial Foundation
Private
United States
US $5,000 - US $100,000
The David Kelby Johnson Memorial Foundation offers grants to 501(c)(3) organizations focused on sight preservation, children's services, and environmental conservation, primarily in Utah. Established in memory of David Kelby Johnson, who tragically lost his life at a young age, the foundation aims to honor his legacy by supporting impactful charitable initiatives. Grants range from $5,000 to $100,000, with a commitment to improving communities both locally and globally.
Eye Diseases & Disorders Vision Impairment Care & Services Senior Services +4 more

McMillen Foundation Grants Program

The Robert B Mcmillen Foundation
Private
United States
Unspecified amount
The McMillen Foundation Grants Program supports research in cardiology, lipids, and organ transplant, along with educational initiatives and social services in Washington and Alaska. With a single grant cycle annually, nonprofits certified under 501(c)(3) can apply for funding, preferably those benefiting children and promoting equity. The foundation emphasizes programs that leverage the arts to foster social change, impacting youth and disadvantaged communities. Applications must be submitted by July 31 to be considered for the current cycle.
Space Physiology & Health Cardiovascular Diseases & Systems Organ And Tissue Banks +6 more

One Hive Foundation Grant

One Hive Foundation
Private
Canada, Connecticut +8 more
Up to US $75,000
The One Hive Foundation Grant focuses on promoting pollinator health and ecologically responsible agriculture through funding research and nonprofit initiatives. Launched in 2022, the grant supports diverse projects aimed at enhancing environmental data, public education, and scientific collaboration. Targeting verified 501c3 organizations, the foundation emphasizes ecological practices and community engagement in Vermont and beyond, with grants of up to $75,000 available to eligible applicants.
Science Communications Food Security Agricultural Pest Management +5 more

NIGMS Institutional Biomedical Undergraduate Research Training Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIGMS Institutional Biomedical Undergraduate Research Training Program aims to enhance the training of undergraduate students in biomedical research. By supporting institutions with limited NIH funding, the program provides trainees with 2–3 years of full-time research training. This initiative fosters a skilled workforce prepared for advanced biomedical degrees, addressing national health-related research needs through comprehensive educational and developmental programs.
Biology Biotechnology Biochemistry +2 more

Transition to Aging Research for Predoctoral Students

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Transition to Aging Research Award for Predoctoral Students, funded by the National Institute on Aging (NIA), invites exceptional graduate students to pursue aging-related postdoctoral training. This two-phase award supports late-stage doctoral candidates in completing dissertation projects across diverse research areas. It aims to facilitate smooth transitions into competitive aging-focused postdoctoral roles, fostering the development of future investigators in aging research. This initiative is designed to enhance collaboration and impactful research in the field of aging.
Aging / Gerontology

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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