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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,702 Results based on applied filters

Henry Hanff Fellowship Award

Ao North America Inc
Private
Europe, North America
Up to US $5,900
The Henry Hanff Fellowship Award offers a unique opportunity for practicing North American trauma surgeons to enhance their skills through a short-term fellowship at a trauma clinic in North America or Europe. Sponsored by AO North America, the fellowship lasts four to eight weeks and covers airfare and a stipend for living expenses, with a total award not exceeding $5,900. Participants must submit a report on their experience for publication, enhancing professional development and collaboration.
Orthopedics Medical Education & Professional Training

AO Spine NA: Young Investigator Research Grant Award

Ao North America Inc
Private
North America
US $20,000
The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.
Spinal Cord Injuries Medical Education & Professional Training Orthopedics

AO North America: Young Investigator Research Development Award

Ao North America Inc
Private
Canada, United States
Up to US $30,000
The AO North America: Young Investigator Research Development Award supports research initiatives for orthopedic trauma fellows in their first year post-fellowship. With a maximum funding of $30,000, the award facilitates professional growth through periodic reporting and networking. Eligible applicants must be fellows in an AO-supported program and current members of AO Trauma, ensuring a commitment to excellence in patient care and outcomes in the field of orthopedic trauma.
Medical Education & Professional Training Orthopedics

CoreCivic Foundation Grant

Corecivic Foundation
Private
United States
Unspecified amount
The CoreCivic Foundation Grant aims to support nonprofit organizations that help former offenders, victims of crime, and underserved youth. Eligible organizations must be 501(c)(3) tax-exempt charities with a commitment to measurable outcomes. Preference is given to those with a history of collaboration with CoreCivic and those operating in Tennessee. This grant provides essential resources to enhance the quality of services delivered to these vulnerable populations, fostering rehabilitation and community support.
Youth Services Reentry Services Crime Victim Services

Crawford Taylor Foundation Grants

Crawford Taylor Foundation
Private
United States
Unspecified amount
The Crawford Taylor Foundation focuses on enhancing programs that create lasting legacies in St. Louis. With priorities in community development, women's health, animal welfare, and environmental preservation, the foundation seeks to support 501(c)(3) organizations that meet specific eligibility criteria. They avoid funding multi-year grants or for-profit initiatives, emphasizing support for local causes and relief efforts deemed important by the Taylor family.
Community Development & Revitalization Women & Girl Services Child Welfare Services +9 more

MCSF- Undergraduate & Associate Degree Scholarship

Marine Corps Scholarship Foundation
Private
United States
US $2,500 - US $10,000
The MCSF- Undergraduate & Associate Degree Scholarship is designed to support the children of Marines and Navy Corpsmen pursuing undergraduate education. To qualify, applicants must demonstrate financial need and maintain a minimum GPA of 2.00. This scholarship can cover various educational expenses such as tuition, books, and transportation. It is an excellent opportunity for those who meet the eligibility criteria and are committed to furthering their education, while honoring the legacy of service in the Marine Corps.
Education - Higher Education Academic Scholarship Programs

NAEMT Foundation Scholarships

National Association of Emergency Medical Technicians
Association/Society
United States
Up to US $1,000
The NAEMT Foundation Scholarships provide financial support for individuals pursuing careers in Emergency Medical Services (EMS). Scholarships are available for those seeking certification as Emergency Medical Responders (EMR) or Emergency Medical Technicians (EMT). Recipients must begin their educational programs in the awarded term and maintain good academic standing. Funds are paid directly to educational institutions. The foundation aims to strengthen the EMS profession through education and research funding.
Emergency Medical Care & Services First Responders

Community Engagement

First Responders Childrens Foundation
Private
United States
Up to US $5,000
The Community Engagement Grant, offered by the First Responders Children's Foundation, aims to strengthen relationships between first responders and youth in their communities. By funding programs that promote mental health, youth education, family support, and emergency assistance, the grant helps foster trust and understanding. This initiative not only benefits first responders and their families but also inspires future generations to consider careers in public service. Together, we can build safer and healthier communities.
Community Services Emergency Medical Care & Services First Responders +1 more

St. Baldrick's Foundation Scholar (Career Development) Award

St Baldricks Foundation Inc
Private
United States
Up to US $330,000
The St. Baldrick's Foundation Scholar (Career Development) Award supports early-career researchers dedicated to childhood cancer research. This three-year award, which can be extended for two additional years based on progress, provides up to $110,000 per year. Founded in 2000, the foundation has mobilized volunteers worldwide to raise funds through head-shaving events and various activities, all aimed at finding cures and improving survivors' lives.
Children’s Health & Pediatrics Pediatric Cancers

St. Baldrick’s Foundation Research Grant Award

St Baldricks Foundation Inc
Private
United States
Up to US $200,000
The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.
Pediatric Cancers

St. Baldrick’s Foundation Fellowship Award

St Baldricks Foundation Inc
Private
United States
Up to US $195,000
The St. Baldrick’s Foundation Fellowship Award supports pediatric oncology training through a two-year fellowship, with a potential third year based on need and achievements. This initiative, powered by community fundraising events, aims to advance research for childhood cancer cures. The award provides a salary capped at $97,500 per year, covering salary and benefits for fellows. This fellowship not only fosters professional growth but also contributes significantly to the fight against childhood cancers.
Pediatric Cancers

Numotion Foundation Grants

Numotion Foundation
Private
United States
US $500 - US $10,000
The Numotion Foundation Grants aim to enhance the lives of individuals with mobility disabilities by supporting IRS-designated 501(c)(3) nonprofit organizations. By fostering partnerships with various charities, including national and local organizations, the foundation raises awareness and funds for necessary research and support services. Contributions are made for each new wheelchair sold, ensuring a coordinated approach to charitable giving while prioritizing programs that specifically assist those with mobility-related challenges.
Disability Care & Services Children With Disabilities Physical Disabilities

Tipgoomoogus Memorial Trust Grant

1992 Tipgoomoogus Memorial Trust
Private
United States
US $5,000 - US $10,000
The Tipgoomoogus Memorial Trust Grant supports organizations dedicated to the care and comfort of small household pets, including dogs, cats, and birds. Founded by Thomas and Ellen Fallon, the trust primarily funds New Jersey-based charities that qualify as 501(c)(3) organizations. Applications are accepted year-round, with a submission deadline of April 30 for annual review. The foundation prefers to assist animal shelters and dog pounds, while excluding funding for salaries or animals raised for commercial or research purposes.
Animal Welfare - Domestic Animals & Pets

Harry Kramer Memorial Fund Grant

Harry Kramer Memorial Fund
Private
Israel, United States
US $10,000 - US $25,000
The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.
Jewish Culture Senior Services Religion & Spirituality +4 more

Downing-Nix Trust Grant

Frances Downing Nix 1013002741
Private
United States
US $6,000 - US $12,000
The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.
Muscular Dystrophy Health Facilities & Clinics Veterinary Science & Services +2 more

Howe Foundation Grant

Howe Foundation 45871100
Private
United States
Approximately US $5,000
The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.
Education Health & Medicine Wildlife Management +1 more

Mother’s Industry Support Fund Grant

Community Foundation of the Ozarks Inc.
Private
Christian County, Missouri, Dallas County, Missouri +3 more
Up to US $250
The Mother's Industry Support Fund Grant provides crucial financial assistance to hospitality workers in the Springfield Metro area who are facing hardships due to the COVID-19 pandemic or other disasters. Eligible applicants can receive support for reemployment costs or basic living expenses, with grants ranging up to $750. This initiative aims to alleviate financial burdens and ensure that affected workers can meet their essential needs during challenging times.
Workforce Preparation & Job Readiness

Hunger to Health Collaboratory (H2HC) 2026 Prizes for Innovation

Newmans Own Foundation
Corporate
United States
Up to US $100,000
The Hunger to Health Collaboratory (H2HC) 2025 Prizes for Innovation aim to enhance health equity for youth through innovative funding in three categories: Food and Nutrition Policy, Nutrition Education & School Food, and Indigenous Food Justice. Supported by Newman’s Own Foundation, these prizes include $100K grants for policy work and $25K grants for education and justice initiatives. Winners will participate in the H2HC Fall Summit in Boston, fostering collaborative solutions to food challenges.
Food Access & Hunger Youth Services Indigenous Sovereignty & Rights +2 more

George William Groh Trust Grant

Groh George W Tr FBO Med Research
Private
United States
US $11,500
The George William Groh Trust Grant supports medical research initiatives by providing funding to organizations that qualify as exempt under Section 501(c)(3) of the Internal Revenue Code. Applications are accepted year-round, with a deadline of May 1 for consideration at the annual grant meeting. The foundation aims to enhance medical research efforts and contribute to advancements in healthcare.
Health & Medicine

Elizabeth Hurlock Beckman Award Trust Grant

The Elizabeth@Hurlock Beckman Award Trust
Private
United States
More than US $25,000
The Elizabeth Hurlock Beckman Award Trust Grant honors educators who inspire students to create impactful organizations or movements. Established in 2008, the trust has awarded over $3.5 million to 148 professors across the U.S. The grant primarily supports those teaching in psychology, medicine, or law, emphasizing the importance of community contribution. Eligibility is limited to U.S. citizens or permanent residents who have inspired their former students to make a difference.
Law Health & Medicine Psychology +1 more

Undergraduate Development Program Student Travel Award

Society of Toxicology
Association/Society
United States
Unspecified amount
The Undergraduate Development Program Student Travel Award offers undergraduate science majors a unique opportunity to attend the Society of Toxicology Annual Meeting from March 21–23, 2026. The program aims to inspire students pursuing research careers in toxicology and related biomedical sciences. Participants will engage with professionals, attend sessions, and explore various educational and career paths. SOT emphasizes inclusiveness, encouraging diverse perspectives to enhance innovation in the field.
Biomedical informatics Environmental Chemistry & Toxicology Education - Higher Education

Undergraduate Development Program Advisor Travel Award

Society of Toxicology
Association/Society
United States
Unspecified amount
The Undergraduate Development Program Advisor Travel Award, hosted by the Society of Toxicology, enables faculty advisors to attend the Undergraduate Development Program from March 21-23, 2026. This initiative aims to familiarize advisors with toxicology and encourage them to guide students toward careers in biomedical sciences. Recipients of the award will participate in educational sessions, networking opportunities, and receive support for travel-related expenses, fostering diversity and innovation within the field.
Environmental Chemistry & Toxicology Biomedical informatics

UPMC Microvascular Reconstructive Fellowship

Upmc
Private
United States
Unspecified amount
The UPMC Microvascular Reconstructive Fellowship offers a one-year clinical program designed for qualified surgeons, focusing on mentorship in microsurgical techniques and comprehensive patient care. Participants will gain hands-on experience in reconstructive surgeries, including extremity trauma and facial reanimation, while also engaging in multidisciplinary cancer treatment. The fellowship emphasizes both clinical and didactic learning, with opportunities for research in renowned laboratories, ensuring fellows acquire a deep understanding of the field.
Medical Education & Professional Training Reconstructive Surgery

Joan M Wismer Foundation Grant

Joan M Wismer Foundation
Private
United States
US $2,500 - US $25,000
The Joan M. Wismer Foundation, established in 2001, honors the legacy of Joan Marilynn Wismer, who was dedicated to charitable work and community service. The foundation focuses on improving lives through education, youth development, safety, humanitarian services, and medical research. It primarily supports IRS-recognized 501(c)(3) organizations, schools, and churches, while emphasizing the importance of sustainable funding and effective financial management in its grant-making process.
Education Youth Services Art & Culture +4 more

Art Bridges Cohort Program

Art Bridges
Private
United States
Unspecified amount
The Art Bridges Cohort Program aims to enhance access to American art by fostering multi-year partnerships among museums across the U.S. This initiative creates sustainable art-sharing ecosystems that promote collaboration and community engagement. The program supports museums through funding for various phases, including research, small art shares, and large art shares, ensuring resources for travel, exhibition design, and educational opportunities. Eligibility includes a strong commitment to community engagement and existing art collections.
Art & Culture Community Culture & Heritage

Firehouse Subs Public Safety Foundation Scholarship Program

Firehouse Subs Public Safety Foundation
Corporate
United States
US $5,000
The Firehouse Subs Public Safety Foundation Scholarship Program supports students aiming to enroll in firefighter, law enforcement, or emergency medical programs at accredited institutions. Established in 2005, the foundation provides $5,000 scholarships to eligible candidates, including high school seniors and current college students. The program emphasizes commitment to public safety and community service, assisting those pursuing careers as first responders. This initiative highlights the foundation's dedication to enhancing lifesaving capabilities within local communities.
Education - Higher Education Firefighting & Fire Prevention Police & Law Enforcement +2 more

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives Clinical Trials Not Allowed

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
Up to US $300,000
The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to enhance the national animal food safety system. This funding opportunity supports state regulatory programs in achieving and sustaining the Animal Food Regulatory Program Standards (AFRPS) within five years. By fostering collaboration with the FDA and standardizing regulatory processes, this initiative seeks to improve food safety, promote compliance, and mitigate foodborne illnesses, ultimately creating a more integrated food safety framework.
Animal Food & Drug Safety

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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