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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,706 Results based on applied filters

Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs (SBIR/STTR): A Pilot Emphasis on Scientific Instrumentation.

U.S. National Science Foundation
Federal Government
American Samoa, Guam +4 more
US $1,250,000 - US $1,555,000
The NSF SBIR/STTR programs are launching a pilot emphasis on advancing scientific instrumentation and enabling technologies to drive innovation and economic growth in the U.S. This initiative supports startups and small businesses developing critical scientific equipment and platforms, with funding opportunities up to $2 million for R&D. By prioritizing next-generation instrumentation, NSF aims to enhance the scientific enterprise and foster breakthroughs essential for the future of AI-driven discoveries and broader scientific advancements.
Science Emerging Technology Development

Goodridge Brothers Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Goodridge Brothers Scholarship, offered by the Saginaw Community Foundation, supports residents of Saginaw County pursuing careers in technical education, such as welding or auto mechanics. This initiative recognizes the growing demand for skilled tradespeople and aims to alleviate financial barriers for students. Scholarships typically range from $500 to $4,000, promoting educational opportunities in urban and regional planning and enhancing the community's workforce capabilities.
Education - Higher Education Education - High School Academic Scholarship Programs

Ken and Eileen Gross Memorial Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Ken and Eileen Gross Memorial Scholarship, established by friends of the couple, supports Saginaw County high school seniors pursuing a teaching degree. With a focus on fostering education, this scholarship honors Ken, a dedicated educator, and Eileen, a successful property manager. Eligible students must demonstrate a minimum 3.0 GPA and financial need, ensuring that those committed to teaching can pursue their aspirations. Awards typically range from $500 to $4,000, empowering the next generation of educators.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

William L. & Mary Ann Brown STEM Endowment Scholarship Program

United Negro College Fund Inc
Private
United States
Unspecified amount

William L. & Mary Ann Brown STEM Endowment Scholarship Program

The William L. & Mary Ann Brown STEM Endowed Scholarship Program was established by William L. and Mary Ann Brown to provide need-based scholarship support to seniors graduating from a high school in Mecklenburg County, North Carolina, enrolled at a UNCF member institution, four-year HBCUs, and four-year institutions.

Successful applicants must be graduating high school seniors entering their first year of college, pursuing a STEM degree, including, but not limited to, fields in physical sciences, mathematics, the biological sciences, the chemical sciences, computer sciences, and engineering. Applicants must be enrolled or planning to enroll as a full-time student.

Education - Higher Education Career / College Preparation STEM / STEAM Education

Improving Metastatic Prostate Cancer (mPCa) Care Through Innovative Strategies

Pfizer, Inc.
Corporate
United States
US $250,000

Improving Metastatic Prostate Cancer (mPCa) Care Through Innovative Strategies

The National Comprehensive Cancer Network® and Pfizer Global Medical Grants (Pfizer) are collaborating to offer a new grant opportunity seeking proposals for investigator-initiated research to improve mPCa care. Pfizer (hereafter, “Grantor”) is providing $1 Million in funding to support quality improvement studies to advance health care quality, the delivery of quality care, and improve health care provider performance in mPCa care. The Grantor will serve as the funding organization. Grants are available to all investigators from institutions within the United States. 

Aim

To promote the advancement of scientific knowledge, health care provider performance, and/or health care quality improvement focused on improving mPCa care.

A total of $1 Million is available to fund all projects. The intent is to fund 2-5 studies. There is a funding cap of $250,000 per study. Exceptional studies with budgets above this amount will be considered based on scientific merit and must contain a robust justification. All budgets must include line-item information and robust justification.

Cancer / Oncology Prostate Cancer

Implementing Germline and Somatic Testing for Precision Medicine in Community-Based Prostate Cancer Care

Pfizer, Inc.
Corporate
United States
Up to US $50,000

Implementing Germline and Somatic Testing for Precision Medicine in Community-Based Prostate Cancer Care 

The intent of this Request for Proposal (RFP) is to invite organizations to submit applications to host a 2.5-to-3 hour medical education program at or nearby the organization, to be led by 1-2 Visiting Professors (VPs) with expertise matched to the organization’s unmet educational and pragmatic needs related to integrating and acting on germline and somatic (tumor and/or ctDNA) testing for patients with prostate cancer. Following the education program, organizations will implement their action plan to incorporate, increase, or improve the use of guideline-concordant germline and somatic testing to improve prostate cancer patient care.

The total budget for the RFP is $250,000 USD, with plans to support 5-7 organizations. Individual project budgets should not exceed $50,000 USD.

Urology Prostate Cancer

Woodrow and Esther Tyrell Technical Scholarship (2026-05-26)

The Community Foundation of Dickinson County Inc.
Private
United States
US $10,000

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.  

Woodrow and Esther Tyrell Technical Scholarship - (Up to 5) $10,000

The Woodrow and Esther Tyrell Technical Scholarship honors the legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose lives reflected a strong commitment to hard work, service, and education. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning to Dickinson County, where he worked for 33 years at the Abilene Flour Mill. Esther Tyrell, originally from Longford, Kansas, dedicated her career to education in Dickinson County. Married in 1952, the Tyrells believed deeply in the value of education and skills-based training. 

Education - Higher Education Vocational & Trade Education Education - High School +1 more

Woodrow and Esther Tyrell Scholarship

The Community Foundation of Dickinson County Inc.
Private
United States
US $20,000

About Us

The Community Foundation of Dickinson County, Inc. was established in 1999 by a group of civic-minded individuals who cherished their community and wanted to ensure future generations experience the same quality of living they had received in Dickinson County. These visionaries secured the future of the Foundation by establishing an Endowed Founder’s Fund.

Woodrow and Esther Tyrell Scholarship - (2 or more) $20,000

The Woodrow and Esther Tyrell Scholarship honors the lives and legacy of Benjamin Woodrow Tyrell and Esther Tyrell, whose commitment to hard work, service, and education continues to benefit students in Dickinson County. Born in Talmage, Kansas, Woodrow Tyrell served in World War II before returning home to work at the Abilene Flour Mill for 33 years. Esther Tyrell, originally from Longford, Kansas, was a longtime educator in Dickinson County. Married in 1952, the Tyrells shared a strong belief in the importance of education. Through their generous endowment at the Community Foundation of Dickinson County, their legacy continues to support students and foster brighter futures through educational opportunity.

Education - Higher Education Vocational & Trade Education Education - High School +1 more

Evidence Based Safety Contextualization of JAK inhibitors in the Treatment of Moderate to Severe Atopic Dermatitis

Pfizer, Inc.
Corporate
China, France +6 more
Up to US $75,000

Evidence Based Safety Contextualization of JAK inhibitors in the Treatment of Moderate to Severe Atopic Dermatitis

Primary Area of Interest:

Dermatology – Atopic Dermatitis

General Area of Interest for this RFP:

Potential applicants should describe their initiative to synthesize the existing medical literature on the safety data available for JAKis indicated for the treatment of M2S AD and distill it into a concise, practical communication for the community of providers who treat AD. The educational initiative should be based on the body of scientific evidence available in the literature including the following, but not limited to:

  • Retrospective, cohort analyses evaluating the background risk of adverse events of special interest (infections, cardiovascular events, malignancies etc.) in patients diagnosed with M2S AD.
  • Clinical trial safety data for use of JAKis for the treatment of M2S AD, including assessments of subpopulations (i.e. adolescents, elderly; cardiovascular risk factors etc.).
  • Observational analyses, network meta-analyses, or other safety analyses, including comparative safety analyses and/or real-world assessments to examine the rate of adverse events of special interest in patients receiving JAKis for treatment of AD.

Funding Range and Project Length

Individual projects requesting up to $75,000 USD will be considered. Maximum project length is 1 year.

Skin Diseases & Dermatology

Judith Heavenrich Memorial Scholarship

Saginaw Community Foundation
Private
United States
US $500 - US $4,000
The Judith Heavenrich Memorial Scholarship, established in memory of Judith Heavenrich, aims to support single, low-income mothers in Saginaw County as they pursue higher education or vocational training. Judith, a lifelong advocate for education and environmental issues, faced numerous challenges in her life but remained dedicated to her community. This scholarship reflects her spirit and commitment to empowering women to achieve their educational goals, with awards typically ranging from $500 to $4,000.
Education - Higher Education Education - High School Academic Scholarship Programs +3 more

The Carver, We’ll Find a Way Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Carver, We’ll Find a Way Scholarship Fund, established by the Carver Family, offers scholarships to local students passionate about helping others. This fund is part of the Community Foundation of Washington County, Maryland, which manages over 100 scholarships aimed at supporting both high school graduates and non-traditional students pursuing further education. The foundation seeks to enhance the quality of life in Washington County through educational support and community engagement.
Education - Higher Education Education - High School Academic Scholarship Programs

The Art Richards Scholarship Fund of Children In Need, Inc.

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Art Richards Scholarship Fund of Children In Need, Inc. offers scholarships to graduating clients of Children In Need, empowering them to pursue secondary education in academics or trades. Established in 1998, this fund was inspired by Art Richards' vision to uplift children living in poverty in Washington County, MD. Through local partnerships, the fund supports educational opportunities and honors community values, ensuring every child has the resources needed to thrive.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

The Artist’s Palette Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Artist’s Palette Scholarship Fund, managed by the Community Foundation of Washington County, MD, supports students pursuing careers in cosmetology, aesthetics, barbering, nail technology, and massage therapy. This fund is designed to assist deserving individuals from Maryland, West Virginia, and Pennsylvania in achieving their educational goals. Scholarships are made possible by local families and organizations dedicated to enhancing community welfare and honoring significant contributions to the community. Applications open annually from January to April.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Research on the Ethical, Legal and Social Implications (ELSI) of Genomics

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Human Genome Research Institute (NHGRI) is set to release a Notice of Funding Opportunity (NOFO) focused on the ethical, legal, and social implications (ELSI) of genomics. This initiative aims to explore how genomics can enhance health and well-being while addressing its broader societal impacts. The NHGRI encourages applications from diverse academic disciplines to promote innovative and replicable research approaches that effectively analyze the consequences of genomic advancements.
Genetics & Genomics Human Genome & Genetics

Samuel Hunter Agricultural Education Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Samuel Hunter Agricultural Education Scholarship, offered by the Community Foundation of Washington County, MD, aims to support students graduating from WCPS high schools, especially those from Smithsburg High School. This scholarship is designed for students pursuing post-secondary education in agricultural fields, with a preference for FFA/4-H participants. With its commitment to enhancing local education, this scholarship not only honors community contributions but also promotes vital career paths in agriculture.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Saint James School Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Saint James School Scholarship Fund provides essential financial assistance to deserving students in the greater Washington County area. Established by local families and organizations, this fund aims to honor individuals and promote education. With over 100 scholarships available through the Community Foundation of Washington County, MD, it supports both high school graduates and non-traditional students pursuing continuing education. This initiative strengthens the community and fosters educational opportunities for all.
Education - Higher Education Education - High School Academic Scholarship Programs

Ryan Myers Memorial Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Ryan Myers Memorial Scholarship Fund, established by the Community Foundation of Washington County, MD, supports graduating seniors from various educational backgrounds in Washington County. This scholarship honors Ryan Myers' legacy, encouraging students pursuing higher education, trade schools, or apprenticeships. Ideal candidates reflect Ryan's positive spirit and aspirations, aiming to make a meaningful impact in their communities while achieving their academic and career goals.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Rotary Club of Hagerstown Sunrise Foundation Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Rotary Club of Hagerstown Sunrise Foundation Scholarship Fund provides financial assistance to graduating high school students and non-traditional learners pursuing a degree or certificate in various fields. This initiative, supported by the Community Foundation of Washington County, aims to honor local contributions and foster educational opportunities. Applicants must demonstrate commitment to community service and leadership. Scholarships open annually in January and close on April 1st, benefiting the community for generations.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Robert and Jenilie Palla Education Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Robert and Jenilie Palla Education Fund offers scholarships to graduating WCPS seniors who have participated in Cross Country and/or Track & Field Teams. This initiative, supported by the Community Foundation of Washington County, Maryland, aims to honor local students and encourage their academic pursuits. With a commitment to enhancing the community's quality of life, the fund exemplifies the importance of education and athletics in shaping future leaders.
Education - Higher Education Education - High School Academic Scholarship Programs

Richard and Mary Myerly Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Richard and Mary Myerly Scholarship, offered by the Community Foundation of Washington County, MD, supports low-income students pursuing careers in photography or fine arts at accredited institutions. Established in memory of Richard and Mary Myerly, this scholarship invites applications from students in Washington County and surrounding areas, promoting educational opportunities and honoring community values. With over 100 scholarships available, this initiative aims to empower the next generation of artists and photographers.
Education - Higher Education Education - High School Academic Scholarship Programs +4 more

Remsberg-Trout Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Remsberg-Trout Scholarship Fund supports local students pursuing STEM degrees. One scholarship assists a senior from Williamsport High School, while two additional scholarships are available for graduates from other Washington County public high schools. All applicants must be members of the National Honor Society. This initiative, part of the Community Foundation of Washington County, MD, aims to foster educational opportunities and enhance the community's future.
Education - Higher Education Vocational & Trade Education Education - High School +2 more

Quinn Alec Hoover Legacy Scouting America Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Quinn Alec Hoover Legacy Scouting America Scholarship Fund supports graduating seniors from Scouting America in the Mason Dixon District, encompassing Washington County, MD, and parts of Pennsylvania. Established by the Community Foundation of Washington County, this scholarship honors the legacy of Quinn Alec Hoover, aiming to recognize and assist students who embody the values of scouting. Applications open annually in January, closing by April 1st, promoting community engagement and educational advancement.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Paul Lawson Memorial Aviation Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Paul Lawson Memorial Aviation Scholarship is dedicated to supporting deserving students aged 15-25 from Maryland and West Virginia who are pursuing aviation lessons. Established in memory of Paul Lawson, this scholarship aims to empower young individuals to achieve their dreams in aviation. Offered by the Community Foundation of Washington County MD, it reflects the commitment of local families and organizations to enhance educational opportunities in the community.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Jon Christopher Gauss, Jr. Wrestling Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount
The Jon Christopher Gauss, Jr. Wrestling Scholarship Fund, established by his parents, supports high school wrestlers pursuing post-secondary education at accredited institutions. This initiative, part of the Community Foundation of Washington County MD, aims to honor Jon's legacy while empowering students to achieve their educational goals. The scholarship enhances community engagement and provides vital financial assistance to promising athletes, ensuring that their dedication to wrestling translates into academic success.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Paul Calabresi Career Development Award for Clinical Oncology aims to enhance the training of clinician-scientists in clinical and translational cancer research. This funding opportunity encourages the career growth of researchers but does not permit Scholars to lead independent clinical trials. Instead, it allows participation in clinical trials under the mentorship of an experienced researcher, fostering a collaborative approach to cancer research.
Cancer / Oncology Biotechnology Health Policy & Advocacy +1 more

Partnership Agreement Grants, FY 2027

National Endowment for the Arts (NEA)
Federal Government
American Samoa, Guam +4 more
US $400,000 - US $1,500,000
The Partnership Agreement Grants for FY 2027, offered by the National Endowment for the Arts (NEA), support state and regional arts agencies in enhancing community arts accessibility. These grants leverage federal funding to attract significantly more state contributions, fostering a robust federal-state partnership. Each state arts agency develops a tailored arts plan, ensuring that local priorities and goals are effectively addressed. This collaborative approach amplifies the impact of federal arts funding across the nation.
Art & Culture Arts / Culture Access & Participation Art Education +2 more

HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $350,000 - US $750,000
The HEAL Initiative aims to combat the opioid crisis through action-oriented research that enhances the translation of addiction epidemiology, prevention, treatment, and recovery services into practice. It prioritizes scalable, evidence-based approaches targeting various levels, including individual and community. The initiative supports a range of methods for research deployment, emphasizing collaboration between researchers and decision-makers to improve outcomes for those affected by addiction and related chronic pain.
Epidemiology & Public Health Addiction & Substance Use Disorders Drug Use Disorder +2 more

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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