Skip to main content
Main content

Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,725 Results based on applied filters

PLTW Gateway - Program Expansion (John Deere)

Project Lead The Way Inc
Private
Aiken County, South Carolina, Alamance County, North Carolina +143 more
US $10,000
The PLTW Gateway program expansion, funded by the John Deere Foundation, aims to enhance access to STEM education for underserved students in John Deere communities. With a commitment to support 1 million youth by 2030, this initiative provides grants to schools seeking to expand their existing PLTW programs. Eligible schools must be within proximity of John Deere facilities and demonstrate a significant enrollment of students participating in free and reduced lunch programs, ensuring equitable educational opportunities.
STEM / STEAM Education Teacher Development & Training

PLTW Computer Science - Program Expansion (John Deere)

Project Lead the Way inc.
Private
Aiken County, South Carolina, Alamance County, North Carolina +143 more
US $10,000
The PLTW Computer Science program, in collaboration with the John Deere Foundation, aims to enhance access and participation in STEM for underserved students in John Deere home communities. This initiative focuses on expanding existing Computer Science programs in schools, ensuring equitable educational opportunities, and developing critical skills through real-world challenges. The partnership is part of a commitment to support 1 million underrepresented youth by 2030, fostering inclusivity in education.
Computer Science & Engineering Teacher Development & Training

PLTW Computer Science - New Program (John Deere)

Project Lead The Way Inc
Private
Aiken County, South Carolina, Alamance County, North Carolina +143 more
US $20,000
The PLTW Computer Science program, funded by the John Deere Foundation, aims to enhance STEM opportunities for underserved students in John Deere communities. This initiative supports schools initiating or expanding PLTW Computer Science courses starting in the 2025-2026 academic year. With a commitment to inclusive education, the foundation seeks to empower students by providing essential resources and opportunities to develop critical skills that will serve them in future careers.
Computer Science & Engineering Teacher Development & Training

MHF: Healthy for Life Cycle Grant

Menorah Heritage Foundation
Private
Cass County, Missouri, Clay County, Missouri +4 more
Unspecified amount
The MHF: Healthy for Life Cycle Grant supports innovative strategies to enhance health and wellness, particularly in underserved communities. By addressing social determinants of health, this grant fosters transformational change, aiming to improve mind, body, and spirit. Organizations with a 501(c)(3) status in the Greater Kansas City area can apply for seed funding to develop impactful initiatives. Successful applications will demonstrate collaboration and a commitment to removing barriers to self-actualization.
Health & Medicine Wellness & Healthy Living Mindfulness, Meditation & Yoga +1 more

Security and Preparedness

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Security and Preparedness (SAP) Program, supported by the National Science Foundation, promotes fundamental research addressing global and national security issues. It emphasizes intellectual merit and broader impacts, encouraging projects that are methodologically sound and empirically driven. Research areas include international relations, political violence, and peace science, among others. The program also fosters undergraduate research experiences and methodological innovations, while strictly avoiding applied research.
International / Foreign Affairs

FPTR: Acute Care Research Grant

Foundation for Physical Therapy Research
Private
United States
US $80,000
The FPTR: Acute Care Research Grant aims to support high-quality research relevant to acute care physical therapy practice. With a total funding of $80,000, this grant encourages innovative studies that can enhance the understanding and application of physical therapy methods. The Foundation for Physical Therapy Research prioritizes projects that address pressing clinical questions and contribute to the evidence base for effective practices while promoting equity in health care.
Physical Therapy

AHRF: Birtman Grant

American Hearing Research Foundation
Private
United States
Up to US $75,000
The AHRF Birtman Grant provides up to $75,000 for one year of research focused on hearing and balance disorders related to the inner ear. This grant encourages both basic and clinical studies, covering direct costs such as staff salaries and research equipment. Applicants must hold relevant advanced degrees and be affiliated with a U.S. university or hospital. An alternative budget option of $50,000 is available, enhancing eligibility for Regular grants if not awarded the Birtman Grant.
Hearing Disorders & Audiology

Genentech: Community Giving

Genentech Foundation
Corporate
United States
Unspecified amount
The Genentech Foundation supports innovative projects that address systemic inequities in healthcare. They fund tax-exempt organizations, including public charities and governmental entities, located in the U.S. Grant requests must be submitted at least 60 days before the project start date. Notably, projects must align with Genentech's commitment to advancing health equity and diversity in the medical workforce. Applications for funding will be accepted starting January 2, 2026, after a temporary closure.
STEM / STEAM Education Medical Education & Professional Training Health Disparities & Social Determinants of Health

AHA: Rapid Response Funding

American Heart Association
Association/Society
United States
Up to US $60,000
The AHA: Rapid Response Funding offers crucial support to nonprofit organizations facing urgent campaign needs in the final stages of policy advocacy. This funding is intended for grassroots organizing, coalition building, polling, and media relations to successfully push for policy passage or defend against harmful legislation. Only organizations that are tax-exempt and have exhausted other resources are eligible, ensuring that funds are directed to campaigns with critical needs.
Health Policy & Advocacy

KaBOOM! Multi-Sport Courts

KaBOOM!
Private
United States
Unspecified amount in in-kind support
KaBOOM! Multi-Sport Courts provide innovative playspaces designed to meet the needs of older youth. These customizable sports courts allow communities to engage in various sports such as basketball and volleyball, addressing the lack of play opportunities. With guidance from KABOOM! Project Managers, applicants can fundraise and collaborate with community members to create an inviting space for active play, ensuring sustainable maintenance and ownership post-project completion.
Sports & Athletics

KaBOOM! Adventure Courses Grant Program

KaBOOM!
Private
United States
Unspecified amount in in-kind support
The KaBOOM! Adventure Courses Grant Program offers funding to create engaging playspaces for older children and teens. This initiative encourages community involvement through a collaborative design and build process, aiming to address the need for physical activity in low-income areas. Eligible applicants include organizations that serve youth and can demonstrate community support. Grants are available on a rolling basis, with a focus on priority cities impacted by recent events, including rural Colorado and Hurricane Harvey-affected Texas communities.
Playgrounds

Jazz Road Tours Grants

South Arts, Inc.
Private
American Samoa, Guam +5 more
Up to US $15,000
Jazz Road Tours Grants provide financial support for emerging and mid-career jazz artists to develop tours across communities in the U.S. Grants up to $15,000 facilitate three-to-six site tours, focusing on underserved areas. This program, funded by the Doris Duke Charitable Foundation and the Mellon Foundation, aims to enhance artists' income opportunities while promoting jazz in diverse venues. Applications are encouraged from individual artists, with deadlines throughout 2024 and 2025 for various tour periods.
Music Festivals

Access Fund: Climbing Conservation Grant

Access Fund
Private
United States
US $1,000 - US $4,000
The Access Fund's Climbing Conservation Grant supports projects that enhance climbing access and conserve the climbing environment across the U.S. Grants typically range from $1,000 to $4,000, with larger requests considered for projects of national significance. Emphasizing local collaboration and measurable outcomes, this program seeks action-oriented initiatives that promote climber responsibility and community engagement, while also adhering to environmental regulations and securing necessary approvals.
Climbing & Mountaineering

ABE Opportunity Grants

American Bar Endowment
Private
American Samoa, Guam +4 more
Up to US $25,000
The American Bar Endowment's Opportunity Grant Program provides funding for innovative, boots-on-the-ground initiatives that address urgent legal needs of the public. This grant focuses on increasing access to justice for underserved populations, improving the justice system, and enhancing public understanding of legal rights. Eligible applicants include public charities and organizations directly impacting local communities, with a strong emphasis on projects that leverage technology and address immediate legal challenges.
Law Legal Services

JDF: FIRST LEGO League Discover

John Deere Foundation
Private
Barnes County, North Dakota, Black Hawk County, Iowa +19 more
Unspecified amount in in-kind support
The John Deere FIRST LEGO League Discover program aims to support equity, diversity, and inclusion in STEM fields by providing grants to teams that meet specific eligibility criteria. Teams must be associated with an educational institution or nonprofit and demonstrate a commitment to recruiting underserved and underrepresented students. The initiative is part of John Deere’s goal to empower one million youth by 2030, fostering innovation and better decision-making in local communities.
STEM / STEAM Education Educational Access & Equity

Deluxe Corp Foundation: ERG Grant Progam

Deluxe Corporation Foundation
Corporate
Anoka County, Minnesota, Bates County, Missouri +28 more
Unspecified amount
The Deluxe Corporation Foundation's ERG Grant Program supports diverse and inclusive initiatives by empowering employee resource groups (ERGs) to partner with nonprofits addressing relevant social issues. Each of the ten ERGs will award a $25,000 grant to a selected organization, fostering community impact and collaboration. The foundation, established in 1954, has invested over $109 million in charitable causes, focusing on financial literacy, education, and community support to enhance lives and promote entrepreneurship.
Financial Literacy STEM / STEAM Education Women's Rights & Equality +10 more

The Simply Organic Giving Fund Grant Program

Simply Organic
Corporate
Canada, United States
US $30,000 - US $100,000
The Simply Organic Giving Fund Grant aims to combat food insecurity in the U.S. and Canada by providing access to nutrient-dense organic food for those in need. Since its inception, the fund has supported various initiatives, including training centers for organic agriculture and community food projects. With a focus on sustainable practices, the grant program seeks to empower communities and improve food access for vulnerable populations, ensuring that healthy, organic options are available to all.
Food Security

World Childhood Foundation - Propose a Program

World Childhood Foundation Inc
Private
United States
Unspecified amount
The World Childhood Foundation aims to eradicate child sexual abuse and exploitation through innovative programs. Organizations eligible for funding must be based in the U.S. and focus on child safety, supportive environments, and responses to abuse. The grant does not support emergency relief, orphanages, or established program costs. Interested applicants should start the process 1-2 months prior to the deadline to ensure they can fulfill the necessary requirements, including a site visit.
Child Welfare Services Crime Victim Services

The Skatepark Project Grants

Tony Hawk Foundation
Private
United States
US $1,000 - US $25,000
The Skatepark Project Grants aim to support underserved communities in building public, free, concrete skateparks for youth. Eligible applicants include public charities and local agencies committed to designing inclusive spaces. The projects must engage local skaters in planning and fundraising, promote safety, and be open year-round without entry fees. The initiative fosters community involvement and addresses social inequalities, ensuring that all types of skatepark users can benefit from these vital recreational resources.
Parks & Public Spaces Youth Services

JDF: FIRST Robotics Competition

John Deere Foundation
Private
Barnes County, North Dakota, Black Hawk County, Iowa +23 more
Unspecified amount in in-kind support
The John Deere FIRST Robotics Competition grant aims to enhance diversity and inclusion in STEM by supporting teams in underserved communities. Teams must apply for funding before registration and meet specific eligibility criteria. This grant promotes equity in engineering and technology through mentorship and community support, aligning with John Deere's commitment to reach one million underserved youth by 2030. Priority is given to teams with confirmed John Deere mentors and those meeting diverse participation requirements.
Robotics

JDF: FIRST LEGO League Explore Grant Program

John Deere Foundation
Private
Barnes County, North Dakota, Black Hawk County, Iowa +19 more
Unspecified amount
The JDF: FIRST LEGO League Explore Grant Program, supported by the John Deere Foundation, aims to enhance participation in STEM for underserved youth. Teams must apply for the grant before registration and ensure compliance with eligibility criteria, including training requirements. This initiative is part of John Deere's commitment to fostering diversity and inclusion in technology and engineering fields, ultimately seeking to impact one million youth by 2030.
STEM / STEAM Education

JDF: FIRST LEGO League Challenge

John Deere Foundation
Private
Barnes County, North Dakota, Black Hawk County, Iowa +19 more
Unspecified amount in in-kind support
The John Deere FIRST LEGO League Challenge aims to enhance equity, diversity, and inclusion in STEM by supporting teams from underserved communities. Eligible teams must have a John Deere mentor and meet specific criteria related to student demographics. Grants will be awarded to teams that demonstrate commitment to community engagement and volunteerism. This initiative aligns with John Deere’s goal to reach one million underserved youth by 2030, fostering innovation and creativity in future generations.
STEM / STEAM Education Robotics

JDF: FIRST Tech Challenge

John Deere Foundation
Private
Barnes County, North Dakota, Black Hawk County, Iowa +17 more
Unspecified amount in in-kind support
The John Deere FIRST Tech Challenge grant supports teams engaging in STEM through robotics. It serves schools and non-profits, prioritizing those in John Deere's Inspire communities and with volunteer mentors. Grants cover registration and equipment costs, fostering innovation and inclusion among underserved students. Teams are encouraged to apply regardless of financial need, furthering John Deere's commitment to empowering youth in engineering and technology through hands-on learning experiences.
STEM / STEAM Education Robotics

MHF: Jewish Community Grant Cycle

Menorah Heritage Foundation
Private
Cass County, Missouri, Clay County, Missouri +4 more
Unspecified amount
The Menorah Heritage Foundation offers the Jewish Community Grant Cycle to support organizations that serve the Greater Kansas City area. Focus areas include health-related programs and initiatives to foster a vibrant Jewish community. Eligible organizations must have 501(c)(3) status and operate within specified geographic parameters. The foundation prioritizes programs that adapt to community needs while ensuring non-discrimination in service provision. Grants may be requested for core operating support or specific programs, with a maximum request of $10,000.
Jewish Culture Judaism Mental Health & Psychiatric Diseases +6 more

Unrestricted Operating Support Cycle (formerly General Community Core)

Menorah Heritage Foundation
Private
Cass County, Missouri, Clay County, Missouri +4 more
Up to US $10,000
The Menorah Heritage Foundation's Unrestricted Operating Support Cycle aims to provide vital operating support to organizations in the Greater Kansas City area. This funding is directed towards essential services such as emergency assistance, shelter, and health care, allowing grantees to allocate resources towards administrative needs and employee benefits. Eligible organizations must maintain 501(c)(3) status and demonstrate a commitment to the community's changing needs, ensuring impactful support for those in need.
Emergency Medical Care & Services Supportive Housing & Shelters Health Care Access & Delivery +4 more

Aging in Community Cycle Grant (formerly Older Adult Cycle)

Menorah Heritage Foundation
Private
Cass County, Missouri, Clay County, Missouri +4 more
Up to US $15,000
The Aging in Community Cycle Grant, offered by the Menorah Heritage Foundation, aims to support organizations that enhance the quality of life for older adults in the Kansas City metro area. The grant provides unrestricted operating funds, program-specific grants, and special project funding for innovative strategies. Eligible organizations must have 501(c)(3) status and focus on issues such as healthcare, housing, and social engagement, ensuring that older adults can thrive in their communities.
Senior Services

Vitamin Angel Association: Grants for US-Based Programs

Vitamin Angel Association Inc.
Private
United States
Unspecified amount in in-kind support
Vitamin Angels offers grants to US-based organizations dedicated to improving nutrition for pregnant women, infants, and young children. By providing prenatal multivitamins and technical support, the initiative aims to reach underserved communities facing nutritional barriers. Eligible organizations must serve at least 500 children or 100 pregnant women annually and distribute the vitamins without financial support from Vitamin Angels. This collaborative effort enhances health outcomes for vulnerable populations across the nation.
Nutrition & Healthy Eating

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

Browse Missouri Grants by Focus Area

Filter Missouri Grants by Location

Browse Grants by Counties within Missouri

Adair County Andrew County Atchison County Audrain County Barry County Barton County Bates County Benton County Bollinger County Boone County Buchanan County Butler County Caldwell County Callaway County Camden County Cape Girardeau County Carroll County Carter County Cass County Cedar County Chariton County Christian County Clark County Clay County Clinton County Cole County Cooper County Crawford County Dade County Dallas County Daviess County DeKalb County Dent County Douglas County Dunklin County Franklin County Gasconade County Gentry County Greene County Grundy County Harrison County Henry County Hickory County Holt County Howard County Howell County Iron County Jackson County Jasper County Jefferson County Johnson County Knox County Laclede County Lafayette County Lawrence County Lewis County Lincoln County Linn County Livingston County Macon County Madison County Maries County Marion County McDonald County Mercer County Miller County Mississippi County Moniteau County Monroe County Montgomery County Morgan County New Madrid County Newton County Nodaway County Oregon County Osage County Ozark County Pemiscot County Perry County Pettis County Phelps County Pike County Platte County Polk County Pulaski County Putnam County Ralls County Randolph County Ray County Reynolds County Ripley County Saline County Schuyler County Scotland County Scott County Shannon County Shelby County St. Charles County St. Clair County Ste. Genevieve County St. Francois County St. Louis City St. Louis County Stoddard County Stone County Sullivan County Taney County Texas County Vernon County Warren County Washington County Wayne County Webster County Worth County Wright County

Browse Grants by Major US Cities within Missouri

Explore Grants Outside of Missouri

Browse Grants by Other States or Regions