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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,514 Results based on applied filters

Rural Health Fellows Leadership Program

National Rural Health Association
Private
United States
Unspecified amount
The Rural Health Fellows Leadership Program, offered by the National Rural Health Association (NRHA), is an intensive yearlong initiative aimed at cultivating a diverse network of rural health leaders. Selected participants engage in leadership training, policy advocacy, and collaborative projects. The program includes monthly virtual sessions, in-person meetings at key conferences, and opportunities for financial support, thereby empowering fellows to make a significant impact on rural healthcare.
Health Disparities & Social Determinants of Health

L.L.Bean Charitable Donations

L.L. Bean
Corporate
American Samoa, Guam +4 more
Unspecified amount
L.L.Bean Charitable Donations supports outdoor initiatives that bring communities together. The program encourages partnerships with inspiring individuals and organizations. To apply, ensure requests are made at least eight weeks before the event. Please note that the program does not fund individuals, advertising, specific schools, or projects outside the U.S. For more information, visit their website to learn how to get involved.
Outdoor Recreation Outdoor Equity

Don Rossi Scholarship

Coastal Community Foundation of South Carolina
Private
United States
Approximately US $1,000
The Don Rossi Scholarship, established by the National Golf Course Owners’ Association in 1993, supports college juniors and seniors majoring in Sports Administration or related fields. This scholarship aims to foster careers in golf-related industries, encouraging students nationwide to pursue their aspirations. Funded by the Coastal Community Foundation, it reflects a commitment to education and community growth, ensuring that financial barriers do not hinder talented individuals from achieving their goals.
Academic Scholarship Programs Golf

OREF Michael P. Kelly Sr Leadership Fellowship Program

Orthopaedic Research and Education Foundation
Private
United States
Unspecified amount
The OREF Michael P. Kelly Sr Leadership Fellowship Program is a one-year virtual fellowship aimed at developing leadership skills in orthopedic residents. The program includes individual coaching, clinical research mentoring, educational opportunities, and an annual leadership retreat. It prioritizes candidates like orthopedic residents (PGY3-PGY5), fellows, and early-career surgeons who show a commitment to orthopedic clinical research and leadership in the orthopedic community.
Orthopedics

OREF/John W. Brown Early-Stage Investigator Enabling Technologies in Musculoskeletal Care Research Grant

Orthopaedic Research and Education Foundation
Private
United States
Up to US $100,000
The OREF/John W. Brown Early-Stage Investigator Grant supports innovative research in musculoskeletal health, encouraging early-stage investigators to submit proposals utilizing enabling technologies. Established by the Orthopaedic Research and Education Foundation, this grant honors John W. Brown's contributions to orthopaedics. With a maximum funding of $100,000 over one or two years, the grant aims to enhance clinical practice and improve patient outcomes through groundbreaking research.
Musculoskeletal Diseases Orthopedics

SAA Shakespeare Publics Award

Shakespeare Association Of America
Private
United States
Unspecified amount
The SAA Shakespeare Publics Award, presented by the Shakespeare Association of America, celebrates innovative efforts that engage diverse publics with Shakespeare's works. Open to SAA members, the award recognizes projects that promote teaching, scholarship, performance, and activism. Since its inception in 1972, the SAA has fostered dialogue and collaboration among scholars, enhancing the appreciation of Shakespeare's impact on culture. This award highlights the importance of broadening access to Shakespeare's legacy in today's society.
Writing & Literature Theater Arts / Culture Access & Participation

SAA First Book Award

Shakespeare Association Of America
Private
United States
Unspecified amount
The SAA First Book Award, presented by the Shakespeare Association of America (SAA), honors the legacy of Jerome Singerman and supports early career scholars. This prestigious award recognizes the best monograph with a significant Shakespeare component, published as the first book by a current SAA member between September 1, 2024, and September 1, 2025. The award will be announced during the SAA’s Annual Luncheon, celebrating contributions to Shakespeare studies.
Writing & Literature

J. Leeds Barroll Dissertation Prize

Shakespeare Association Of America
Private
United States
Unspecified amount
The J. Leeds Barroll Dissertation Prize, awarded by the Shakespeare Association of America, honors exemplary doctoral work with a significant focus on Shakespeare. This prestigious award is conferred annually during the SAA’s Annual Luncheon. To be eligible, applicants must be SAA members in good standing, and dissertations must be approved between September 1, 2024, and September 1, 2025. This prize encourages innovative research and scholarship in Shakespeare studies.
Writing & Literature

Barbara Hodgdon Award

Shakespeare Association Of America
Private
United States
Unspecified amount
The Barbara Hodgdon Award, presented by the Shakespeare Association of America (SAA), honors exceptional scholarship in the field of Shakespeare and Performance. Established in memory of Barbara Hodgdon, this award encourages innovative research across various media and time periods related to Shakespeare's work. Eligible submissions must be authored by SAA members and published two years prior to the award presentation. This recognition promotes new discussions and insights within the realm of Shakespearean performance studies.
Writing & Literature Conceptual Art / Performance Art

Faculty Travel Grant for AGU Annual Meeting

AGU- Advancing Earth and Space Science
Private
United States
US $1,700
The Faculty Travel Grant for AGU Annual Meeting supports early-to-mid career faculty from under-resourced institutions, including community colleges and minority-serving institutions. This program aims to facilitate attendance at the AGU Annual Meeting, which attracts over 22,000 geoscience professionals globally. Awardees receive a $1,700 travel stipend, access to professional development workshops, and networking opportunities, enabling them to enhance their research and teaching capabilities through collaboration and innovation.
Teacher Development & Training

IATSE Local 600 Hardship Fund Grant

Entertainment Community Fund
Association/Society
United States
Unspecified amount
The IATSE Local 600: Traditional Hardship Fund Grant provides emergency financial assistance to performing arts and entertainment professionals in times of unexpected need. This grant supports basic living expenses like healthcare and housing, aiming to prevent eviction or shut-offs. Eligible members must have been in good standing for at least two years and have faced work loss due to illness or disasters. The fund ensures support during critical times, promoting stability within the community.
Performing Arts Poverty Alleviation & Services

Path to a Cure — Collaborative Research Grant

Cystic Fibrosis Foundation
Private
United States
Up to US $1,000,000
The Path to a Cure — Collaborative Research Grant, offered by the Cystic Fibrosis Foundation, aims to support research in developing new therapies for cystic fibrosis, particularly focusing on CFTR gene repair and replacement strategies. This program prioritizes collaborations that integrate new investigators and innovative technologies into CF research. Applicants can request up to $1,000,000 annually for three years, with proposals requiring preliminary data to demonstrate feasibility and potential impact.
Cystic Fibrosis

David Perlman Award for Excellence in Science Journalism - News

AGU- Advancing Earth and Space Science
Private
United States
More than US $5,000
The David Perlman Award for Excellence in Science Journalism recognizes outstanding work in science news reporting. Established in 2000, this annual award honors journalists who make Earth and space science accessible to the public. Recipients receive a $5,000 prize, an engraved award, and recognition at AGU's annual meeting. Eligible nominees include journalists from any medium, excluding books, who have not won the award in the past two years. The award encourages diverse representation in science journalism.
Journalism Science Communications

IATSE Local 700 Hardship Relief Fund

Entertainment Community Fund
Association/Society
United States
Unspecified amount
The IATSE Local 700 Hardship Relief Fund provides emergency financial assistance to eligible members of the performing arts and entertainment industry during critical times. This support helps cover essential living expenses, such as housing and healthcare, to prevent eviction and utility shut-offs. To qualify, members must have met minimum dues requirements or be officially retired. The fund does not cover expenses like credit cards, loans, or business-related costs.
Basic Human Needs Disaster Relief / Humanitarian Aid

IATSE Local 798 Fund

Entertainment Community Fund
Association/Society
United States
Unspecified amount
The IATSE Local 798 Fund offers emergency financial assistance to performing arts and entertainment professionals facing unexpected critical needs. This support helps cover essential living expenses, including housing, utilities, and healthcare, to prevent eviction or service shut-offs. Eligible applicants must be union members for at least two years and have experienced unforeseen financial hardship due to circumstances beyond their control, such as injury or natural disasters.
Disaster Relief / Humanitarian Aid

Harry A. Saunders III Memorial Fund

Hawai'i Community Foundation
Private
United States
Unspecified amount
The Harry A. Saunders III Memorial Fund, established in 2025 by the Hawai‘i Community Foundation, supports Hawaii high school graduates pursuing higher education. This fund aims to empower students demonstrating financial need and maintaining a minimum GPA of 2.0. Preference is given to recipients who were awarded in the previous year, provided they continue to meet eligibility requirements. The fund embodies a commitment to fostering educational opportunities and enriching the lives of young Hawaiians.
Education - Higher Education Academic Scholarship Programs

Waldenstrom Macroglobulinemia Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Waldenstrom Macroglobulinemia Fund provides crucial financial assistance to underinsured patients suffering from this rare blood cancer. Through the HealthWell Foundation, the fund helps cover prescription copays, insurance premiums, and treatment-related costs, ensuring access to necessary medical care. With over $1.2 billion in grants awarded, the program has supported more than 1.1 million patients since its inception in 2004. Its mission is to alleviate financial barriers to essential healthcare, allowing patients to focus on their treatment and recovery.
Cancer / Oncology Immune System Diseases Health Care Access & Delivery

Systemic Sclerosis with Interstitial Lung Disease Fund

Healthwell Foundation
Private
United States
Up to US $9,000
The Systemic Sclerosis with Interstitial Lung Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from systemic sclerosis. This rare autoimmune disease leads to excessive collagen production, causing serious health issues. The fund assists with prescription copays and insurance premiums to ensure patients receive necessary treatments. In 2024, HealthWell awarded over $1.2 billion in grants, supporting more than 1.1 million patients in accessing vital healthcare services.
Cardiovascular Diseases & Systems Neurological Diseases & Disorders Multiple Sclerosis +3 more

Porphyrias Fund

Healthwell Foundation
Private
United States
Up to US $4,000
The Porphyrias Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from porphyrias, a group of eight disorders characterized by the accumulation of porphyrins in the body. The fund assists with prescription drug copays and insurance premiums, offering up to $4,000 in financial aid. Established to ensure no patient lacks necessary treatment due to costs, the foundation has awarded over $1.2 billion since 2004, supporting more than 1.1 million patients.
Health Care Access & Delivery Endocrine & Metabolic Diseases Rare Diseases

ACS - Fanconi Cancer Foundation Discovery Boost Grant

American Cancer Society
Association/Society
United States
More than US $135,000
The ACS - Fanconi Cancer Foundation Discovery Boost Grant invites innovative proposals for translational cancer research addressing the challenges faced by individuals with Fanconi anemia (FA). This grant supports high-risk, high-reward projects aimed at improving detection, prevention, or treatment of FA-related cancers. With funding of up to $135,000 per year for two years, it encourages research in early detection technologies, prevention mechanisms, and therapeutic strategies tailored to the unique sensitivities of the FA population.
Cancer / Oncology

Metabolic Dysfunction-Associated Steatohepatitis Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Metabolic Dysfunction-Associated Steatohepatitis Fund, established by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients facing chronic illnesses. It provides critical support for expenses related to prescription copays, insurance premiums, and transportation for treatment. With a maximum award of $8,000, the fund ensures that individuals can access necessary healthcare services without financial strain. This initiative emphasizes the commitment to improving health outcomes for those affected by metabolic dysfunction-associated steatohepatitis.
Health Care Access & Delivery Liver Disease Cystic Fibrosis +1 more

Mantle Cell Lymphoma Fund

Healthwell Foundation
Private
United States
Up to US $8,500
The Mantle Cell Lymphoma Fund, managed by the HealthWell Foundation, provides financial assistance to underinsured patients diagnosed with Mantle Cell Lymphoma. The fund covers prescription drug copays and Medicare Part B premiums, with a maximum award of $8,500. Eligible patients must have insurance that covers their medication and meet specific income guidelines. The foundation aims to reduce financial barriers to essential treatments, ensuring that patients receive necessary care without undue financial strain.
Health Care Access & Delivery Lymphoma Cancer / Oncology

Inborn Metabolic or Genetic Bile Acid Deficiency Vitamins and Supplements Fund

Healthwell Foundation
Private
United States
Up to US $1,000
The HealthWell Foundation's Inborn Metabolic or Genetic Bile Acid Deficiency Vitamins and Supplements Fund provides essential financial assistance for individuals facing significant health challenges. By covering copays, deductibles, and related expenses, the fund aims to alleviate the financial burden on underinsured patients. With a commitment to enhancing healthcare access, the Foundation has awarded over $1.2 billion since its inception, ensuring that vital treatments remain accessible to those in need.
Endocrine & Metabolic Diseases Health Care Access & Delivery Genetic Conditions & Birth Defects

Hyperoxaluria Fund

Healthwell Foundation
Private
United States
Up to US $8,000
The Hyperoxaluria Fund, managed by the HealthWell Foundation, aims to alleviate financial burdens for underinsured patients suffering from hyperoxaluria, a condition characterized by excessive oxalate in urine. This fund assists with prescription drug copays and insurance premiums, providing vital support for treatments. In 2024 alone, HealthWell allocated over $1.2 billion in grants, ensuring access to essential medications for those in need. The organization is committed to improving healthcare access and reducing disparities for affected individuals.
Health Care Access & Delivery Kidney Diseases Genetic Conditions & Birth Defects

Emergency/Medical Workers Behavioral Health Fund

Healthwell Foundation
Private
United States
Up to US $2,000
The Emergency/Medical Workers Behavioral Health Fund aims to support emergency workers facing trauma and anxiety due to their roles. Established by the HealthWell Foundation, it provides financial assistance for treatment-related costs, including copayments for prescription drugs, counseling, and transportation. In 2024, the Foundation awarded over $1.2 billion to underinsured patients, ensuring no one is denied essential healthcare due to financial barriers. This initiative helps address the critical mental health needs of those who serve on the front lines.
Crisis Intervention Emergency Medical Care & Services Public Transportation & Mass Transit Systems +4 more

Dupuytren’s Disease Fund

Healthwell Foundation
Private
United States
Up to US $3,500
The Dupuytren’s Disease Fund, managed by the HealthWell Foundation, aims to reduce financial barriers for underinsured patients suffering from Dupuytren's Disease. This fund provides assistance for prescription drug copays and insurance premiums related to treatment. With an average grant utilization of $1,650 over a 12-month period, the fund ensures that essential medications and therapies are affordable. HealthWell Foundation, a private non-profit, has helped over 1.1 million patients since 2004, demonstrating its commitment to healthcare access.
Health Care Access & Delivery Skin Diseases & Dermatology

Cushing's Disease or Cushing's Syndrome Fund

Healthwell Foundation
Private
United States
Up to US $10,000
The Cushing's Disease or Cushing's Syndrome Fund, operated by the HealthWell Foundation, provides vital financial assistance to underinsured patients facing high medical costs associated with these conditions. The fund covers co-payments, insurance premiums, and necessary treatments, ensuring that patients receive the care they need without financial burden. With an average grant utilization of $3,000 over twelve months, this fund aims to alleviate the challenges of treatment accessibility, supporting both physical and mental health for those affected.
Health Care Access & Delivery Endocrine & Metabolic Diseases

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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