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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,702 Results based on applied filters

Frances Parker Rupert Memorial Fund for Music and the Performing Arts

Community Foundation Serving Western Virginia
Private
United States
Approximately US $3,000
The Frances Parker Rupert Memorial Fund for Music and the Performing Arts provides scholarships to talented students pursuing music or performing arts degrees. Established by the Community Foundation Serving Western Virginia, this fund aims to support high school seniors from specific counties, considering their potential and financial need. Applicants must demonstrate their artistic abilities and articulate how this scholarship will aid their educational goals in a two-page essay.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs +2 more

Edwin K. Mattern, Jr. Memorial Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $2,000
The Edwin K. Mattern, Jr. Memorial Scholarship Fund, managed by the Community Foundation Serving Western Virginia, supports graduating seniors from the Roanoke Valley pursuing higher education in engineering or architecture. This renewable scholarship emphasizes academic achievement and financial need, requiring recipients to maintain a minimum GPA. Established to empower deserving students, the fund reflects the foundation's commitment to fostering educational opportunities in the community.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Dorothy and Julien Meyer, Sr., M.D. Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $500
The Dorothy and Julien Meyer, Sr., M.D. Scholarship Fund, managed by the Community Foundation Serving Western Virginia, provides scholarships to graduating seniors from Roanoke Valley high schools pursuing premedical studies. This fund aims to support deserving students with financial need, ensuring they can achieve their educational goals. The Foundation administers various scholarships and encourages students to inquire for detailed eligibility criteria and application processes.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Dillon Family Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,500
The Dillon Family Scholarship Fund, established by James M. Dillon, provides financial assistance for higher education to deserving students from specific regions in Virginia. Administered by the Community Foundation Serving Western Virginia, this scholarship supports students who demonstrate financial need and academic potential. Eligible candidates must be graduating seniors from designated public high schools, enrolling in accredited colleges or trade schools. Preference is given to graduates from Alleghany High School, ensuring targeted support for local students.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Davis B. and Barbara J. Francis Scholarship Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Davis B. and Barbara J. Francis Scholarship Fund, established by the Community Foundation Serving Western Virginia, provides educational scholarships to deserving students in the Roanoke Valley. It aims to support graduating seniors or former graduates pursuing careers in technical theatre or performing arts. Applicants must demonstrate significant contributions to their school's theatre arts program and enroll in an accredited college or technical school. Financial need is considered but not the primary criterion.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Clarence Lee Lester Educational Fund

Community Foundation Serving Western Virginia
Private
United States
Approximately US $1,000
The Clarence Lee Lester Educational Fund, administered by the Community Foundation Serving Western Virginia, provides scholarships to deserving students pursuing higher education. Eligible applicants must be graduating seniors with a minimum 2.5 GPA and a connection to First Baptist Church in Martinsville, VA. This scholarship aims to support capable individuals in their academic journeys, ensuring that financial barriers do not hinder their educational aspirations. For more information, contact the Foundation directly.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

PERF: Career Development Grants - CNS Shields Research Grant

Pediatric Epilepsy Research Foundation
Private
Canada, United States
US $150,000
The PERF: Career Development Grants - CNS Shields Research Grant supports early-stage investigators in pediatric neurology research. Offered by the Pediatric Epilepsy Research Foundation and the Child Neurology Society, this grant provides $150,000 over two years. Eligible applicants must be within 10 years of completing their terminal degree and have not received independent funding. The grant emphasizes clinical research, fostering advancements in the treatment of pediatric neurological conditions.
Neuroscience Neurological Diseases & Disorders Children’s Health & Pediatrics +1 more

EMF/EMRA Resident Research Grant

Society for Academic Emergency Medicine Foundation
Private
United States
Up to US $10,000
The EMF EMRA Resident Research Grant, funded by the Society for Academic Emergency Medicine Foundation, aims to enhance research in emergency medicine by providing up to $10,000 for residents in accredited programs. This grant promotes the development of future researchers, improves patient care, and supports effective health policy through rigorous scientific inquiry. Eligible applicants must be ACGME-approved residents and secure a faculty preceptor's support, ensuring a robust educational experience in research methodologies.
Emergency Medical Care & Services Preventative Healthcare Epidemiology & Public Health +2 more

NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional) (351692)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) aims to support high-risk, multi-center clinical studies by facilitating early peer review and assessment of study designs. This program helps in the development of necessary operational documents and essential elements for conducting hypothesis-driven studies focused on diseases relevant to NIDDK. Applications are due by 5:00 PM local time, and consulting with NIDDK staff is strongly encouraged.
Diseases & Conditions Digestive System Health & Diseases Kidney Diseases +1 more

Alpha Gamma Delta Foundation: Fighting Hunger Grants

Alpha Gamma Delta Foundation Inc
Private
Canada, United States
Up to US $10,000
The Alpha Gamma Delta Foundation provides grants aimed at combating hunger in the U.S. and Canada, focusing on direct food assistance, food rescue, and nutrition education. Eligible organizations can receive up to $10,000 in funding, with an average grant size of $5,000. Since its inception, the Foundation has awarded over $2 million to support local food programs, ensuring communities have access to essential resources and assistance for those in need.
Food Access & Hunger Food Security Food Delivery & Distribution Services +1 more

ECosystem for Leading Innovation in Plasma Science and Engineering

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The ECosystem for Leading Innovation in Plasma Science and Engineering (ECLIPSE) program aims to advance plasma science research by addressing societal challenges through multidisciplinary collaboration. It encourages proposals that integrate fundamental scientific inquiries with technological applications, fostering innovation in areas such as environmental remediation, advanced manufacturing, and nanotechnology. Proposals should align with NSF priorities and promote diversity in STEM, enhancing workforce development and broadening participation from underrepresented groups.
Physics Materials Science and Engineering Space Science +1 more

Friends Foundation for the Aging Grant

Friends Foundation for the Aging
Private
United States
Unspecified amount
The Friends Foundation for the Aging Grant supports innovative and impactful programs aimed at addressing the needs of older adults, particularly within underserved populations. This Quaker foundation prioritizes collaboration and sustainability in its funding efforts. Eligible applicants must be 501(c)(3) public charities focused on enhancing the quality of life for aging individuals. Grants are typically awarded for one year and target organizations that align with the foundation's mission and values.
Aging / Gerontology Senior Services Protestantism +1 more

Young Investigator Research Grant Program

National Kidney Foundation Inc
Private
United States
Up to US $25,000
The National Kidney Foundation's Young Investigator Research Grant supports clinical research on kidney disease. It aims to foster innovation in patient-oriented studies, including technology development and clinical trials. Eligible applicants are junior faculty in the U.S. who have completed nephrology training. The grant provides up to $35,000 for one year, with potential renewal. Funds cover research costs, salaries, and limited travel, while prohibiting indirect costs and patient care expenses.
Kidney Diseases

Kidney Health Equity Community Engagement Award

National Kidney Foundation Inc
Private
United States
US $75,000
The Kidney Health Equity Community Engagement Award by the National Kidney Foundation aims to enhance health equity in kidney care. This award encourages innovative proposals that address disparities in access to kidney care, education, and treatment. With a funding of $75,000 for one year, it supports healthcare professionals and researchers in implementing community-based solutions to improve outcomes for individuals affected by kidney disease. The initiative seeks to dismantle barriers and foster equitable health practices.
Kidney Diseases Health Disparities & Social Determinants of Health

Council of Nephrology Nurses and Technicians (CNNT) Research Grant

National Kidney Foundation Inc
Private
United States
US $10,000
The Council of Nephrology Nurses and Technicians (CNNT) Research Grant, funded by the National Kidney Foundation, offers $10,000 annually for research that enhances kidney disease management. Eligible applicants must be NKF-CNNT members with at least two years of nephrology experience. Research topics include social work interventions, patient education, and innovative treatment strategies aimed at improving patient outcomes and addressing health disparities in kidney care.
Kidney Diseases

Chronic Pain Medicine Research Grant

American Society of Regional Anesthesia (ASRA) and Pain Medicine
Private
North America
Up to US $75,000
The Chronic Pain Medicine Research Grant, offered by the American Society of Regional Anesthesia (ASRA) and Pain Medicine, aims to enhance research in pain medicine, guiding clinical practice and improving patient care. With a funding limit of $200,000, the grant prioritizes studies in areas such as Regional Anesthesia, Outcomes Research, and Patient Safety, encouraging innovative proposals from North American physician members of ASRA.
Chronic / Acute Pain Patient Care & Services Drug Safety +1 more

Value Assessment and Health Outcomes Research Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The Value Assessment and Health Outcomes Research Postdoctoral Fellowship, funded by the PhRMA Foundation, offers a $60,000 stipend annually for up to two years. This fellowship supports researchers, both U.S. and non-U.S. citizens, engaged in innovative studies aimed at evaluating the effectiveness and value of healthcare interventions. Applicants must be within five years of postdoctoral study and hold a relevant doctoral degree. This opportunity fosters collaboration and patient engagement in health outcomes research.
Health & Medicine Health Disparities & Social Determinants of Health Health Care Access & Delivery +1 more

Value Assessment and Health Outcomes Research Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Value Assessment and Health Outcomes Research Predoctoral Fellowship, offered by the PhRMA Foundation, supports promising students in their advanced training and thesis research. This fellowship, aimed at U.S. and non-U.S. citizens, provides $30,000 in annual stipend support for up to two years. It encourages research proposals that address the effectiveness, safety, and value of healthcare interventions, emphasizing patient engagement and health equity in the evaluation process.
Health & Medicine Health Care Access & Delivery Health Disparities & Social Determinants of Health +1 more

Translational Medicine Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The Translational Medicine Postdoctoral Fellowship by the PhRMA Foundation supports U.S. and non-U.S. citizens in multidisciplinary research training at accredited U.S. universities. The program aims to enhance credentials in translational medicine, focusing on turning laboratory observations into effective medical interventions. The fellowship includes a stipend of $60,000 per year for 12 to 24 months, promoting innovative research that addresses unmet clinical needs in various scientific disciplines.
Health & Medicine

College Well-Being-Award

American College Health Foundation
Corporate
United States
Up to US $3,500
The College Well-Being Funding Opportunity aims to enhance the health of college students through innovative programs and research. Offered by the American College Health Foundation, it provides up to two awards of $3,500 to eligible institutions for improving campus infrastructure that promotes student well-being. This initiative encourages creativity and collaboration among campus health professionals to develop effective, measurable outcomes in student wellness. By fostering a culture of well-being, the foundation seeks to address the evolving needs of contemporary students.
Education - Higher Education Wellness & Healthy Living

Beth N. Rom-Rymer Travel Scholarship for Native Psychology Students

American Psychological Foundation Inc
Private
United States
US $1,000
The Beth N. Rom-Rymer Travel Scholarship provides $1,000 for Native psychology graduate students to attend the American Psychological Association's annual convention. This opportunity is specifically for members of the Society of Indian Psychologists (SIP). The scholarship aims to support diverse applicants and encourages first-time attendees who demonstrate financial need. APF, the funding organization, is dedicated to enhancing the field of psychology by supporting early career professionals and their contributions to societal improvement.
Native American Services Psychology

Drug Discovery Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Drug Discovery Predoctoral Fellowship by the PhRMA Foundation supports PhD candidates engaged in thesis research in drug discovery. This fellowship offers $30,000 annually for 12 to 24 months, encouraging innovative research that integrates multiple scientific disciplines. Applicants must be full-time, in-residence students at accredited U.S. universities and have completed significant coursework. The funding is conditional upon continued enrollment and is intended for stipend support, with some funds allowable for research-related incidentals.
Pharmacology

Drug Delivery Predoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $60,000
The Drug Delivery Predoctoral Fellowship by the PhRMA Foundation supports promising PhD candidates in drug delivery research at accredited U.S. universities. It provides $30,000 per year for 12 to 24 months, aimed at enhancing the understanding of drug formulation and delivery technologies. The fellowship emphasizes innovative research that leads to improved patient outcomes and fosters collaboration among diverse research teams, ensuring that all individuals have access to groundbreaking medicines.
Pharmacology

Drug Delivery Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The PhRMA Foundation offers a Drug Delivery Postdoctoral Fellowship aimed at fostering biopharmaceutical innovation and enhancing research capabilities in drug delivery. This fellowship supports both U.S. and non-U.S. citizens who are involved in collaborative research training at accredited U.S. universities. Awardees receive a stipend of $60,000 per year for 12 to 24 months, with funding contingent on ongoing employment in the postdoctoral program. Ideal candidates are encouraged to expand their skills in new research environments.
Pharmacology

Drug Discovery Postdoctoral Fellowship

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
Up to US $120,000
The Drug Discovery Postdoctoral Fellowship by the PhRMA Foundation supports researchers in a multidisciplinary training program at accredited U.S. universities. Aimed at enhancing credentials in drug discovery, it funds innovative research with potential human applications. Proposals should focus on biological validation of drug targets across various scientific disciplines. The fellowship provides $60,000 in annual stipend support for up to 24 months, contingent on the awardee's continued employment at the university.
Pharmacology

PERF: CNS Bridge Grant Program

Pediatric Epilepsy Research Foundation
Private
Canada, United States
Up to US $100,000
The PERF: CNS Bridge Grant Program aims to support emerging child neurology researchers by providing essential bridge funding while they seek independent research grants from NIH or CIHR. Established by the Pediatric Epilepsy Research Foundation in collaboration with the Child Neurology Society, this initiative seeks to retain talented investigators in the field of pediatric neurology. Since its inception, the foundation has awarded over $18 million to advance pediatric epilepsy research and related conditions.
Children’s Health & Pediatrics Neuroscience Epilepsy

OTA Young Investigator Research Grant

Orthopaedic Trauma Foundation Inc
Private
Canada, United States
US $35,000
The OTA Young Investigator Research Grant aims to support early-career orthopedic trauma surgeons within five years of fellowship completion by providing $35,000 over two years. This funding promotes mentored research and development in orthopaedic trauma, encouraging innovative projects that demonstrate clinical relevance. Collaborating with AO Trauma North America and COIRI, the OTA facilitates access to resources like mentoring programs and grant libraries, fostering leadership and excellence in research and education.
Musculoskeletal Diseases Medical Education & Professional Training

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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