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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,702 Results based on applied filters

Mellon Emerging Faculty Leaders Award

Institute for Citizens & Scholars
Private
United States
US $20,000
The Mellon Emerging Faculty Leaders Award supports early-career faculty committed to building inclusive campus communities. Funded by the Mellon Foundation, it offers a $20,000 stipend to assist with summer research and academic year support. Eligible candidates are assistant professors in tenure-track positions who have passed their third-year review and are engaged in fostering diversity and inclusion in their academic fields. This fellowship not only aids their research but also emphasizes their role in mentoring underrepresented students.
Humanities & Social Science

MMUF Dissertation Grant

Institute for Citizens & Scholars
Private
United States
Up to US $30,000
The MMUF Dissertation Grant, funded by the Mellon Foundation, supports doctoral candidates who are alumni of the Mellon Mays Undergraduate Fellowship. This grant aids scholars in completing their dissertations, ensuring diverse perspectives are represented in academia. With up to $30,000 for a 12-month period, the program encourages candidates to secure additional funding from their institutions. The initiative aims to bolster access to education and foster understanding among varied backgrounds, ultimately enhancing the academic landscape.
Humanities & Social Science Art & Culture Religion & Spirituality +11 more

MMUF Advancement Program - The Adjunct Faculty Fellowships

Institute for Citizens & Scholars
Private
United States
US $10,000
The MMUF Advancement Program offers Adjunct Faculty Fellowships designed for alumni of the Mellon Mays Undergraduate Fellowship. These fellowships provide essential resources and time to focus on research and scholarship, aiding individuals in securing tenure-track positions. Each fellow receives a $10,000 stipend, a six-month award period, a mentor, and funding to attend a conference. This initiative supports diverse perspectives in higher education, fostering an inclusive academic environment.
Art & Culture Humanities & Social Science Religion & Spirituality

Mellon Mays GAP

Institute for Citizens & Scholars
Private
United States
Unspecified amount
The Mellon Mays Graduate Assistance Program (GAP) supports alumni of the Mellon Mays initiative in their journey to graduate school. By providing resources like structured gap year activities, media resources, and mentoring, the program aims to bridge the transition from undergraduate to graduate studies. It has successfully placed over 90 scholars in advanced programs, fostering diverse perspectives in academia. GAP addresses challenges faced during the gap year, ensuring participants remain engaged and prepared for their academic careers.
Humanities & Social Science

Dot Foods’ Charitable Grant Program: $500 or more

Dot Foods
Corporate
Brown County, Illinois, Canada +15 more
More than US $500
Dot Foods’ Charitable Grant Program supports 501(c)(3) nonprofits, schools, and government entities with grants of $500 or more. The program emphasizes community development, diversity and inclusion, education, health and wellness, and public safety. Organizations must be located near Dot Foods facilities and align their requests with these focus areas. This initiative reflects Dot Foods’ commitment to making a positive impact in the communities it serves through active employee engagement and local charitable efforts.
Community Development & Revitalization Civic Engagement & Education Diversity, Equity & Inclusion +4 more

Dot Foods’ Charitable Grant Program: Small Grants ($500 or less)

Dot Foods
Corporate
Brown County, Illinois, Canada +15 more
Up to US $500
Dot Foods’ Charitable Grant Program offers small grants of $500 or less to support local nonprofits, schools, and government entities. This initiative aims to enhance community development, education, health, diversity, and safety. Dedicated employees at Dot Foods volunteer their time to manage fundraising efforts and grant approvals, ensuring that contributions effectively impact their local areas. Organizations must align their requests with these focus areas and be located near a Dot Foods facility to be eligible.
Education Civic Engagement & Education Health Care Access & Delivery +4 more

Conserving Black Modernism Grant Program

National Trust for Historic Preservation
Private
United States
US $150,000

Conserving Black Modernism Grant Program

The African American Cultural Heritage Action Fund (AACHAF), a program of the National Trust for Historic Preservation, has launched the Conserving Black Modernism grant program through funding from and a partnership with the Getty Foundation’s Keeping it Modern initiative. The Conserving Black Modernism grant program is designed to empower and equip preservationists and stewards with funding and technical support to preserve the material heritage, innovation, and legacy of modern architectural sites designed by Black architects.

Integrated into the Action Fund’s existing National Grant Program, the Conserving Black Modernism grant program will support non-profits and municipalities to steward 16 historic assets of modern architecture through funding, technical assistance, public awareness, and education. The program will support eligible project planning activities and seeks to develop future-looking plans that model and strengthen stewardship, interpretation, and asset management. This program aims to increase recognition of Black architects and their artistic expressions as well as diversify the meaning of American modern architecture and design. The Action Fund invites proposals from a broad pool of applicants who steward these places for public benefit and access.

Grants made from Conserving Black Modernism will total $150,000 each. Funding will be flexible and can support planning activities, limited capital improvements, and indirect costs. Funding ratios will be balanced to support and prioritize comprehensive project planning needs. For example, a $150,000 project planning grant with 10% indirect can be allocated to advance a full-scale building evaluation and preservation plan. The grant period for this type of project will be 12 months.

Conserving Black Modernism grants can also support projects consisting of a mix of project planning and limited capital improvements. Funding ratios will be balanced to prioritize project planning. For example, an applicant may propose a project which allocates $90,000 for planning activities, $45,000 for capital expenses, and $15,000 for indirect expenses. The grant period for this type of project will be 18 months.

Grantees can address the building’s priority needs and experience the full cycle of planning, design, and construction. Additional grantee support will include technical assistance, promotion, and conservation management training.

Historic Asset Example Archetypes

While this is not an exhaustive list, we are particularly interested in the following 20th-century property archetypes:

  • Buildings Located on HBCU Campuses
  • Community and Cultural Centers
  • Schools
  • Libraries
  • Houses and Residences
  • Spaces Associated with Sports & Recreation
  • Green Book Sites
  • Sites associated with Women’s History
  • Sites associated with LGBTQ+ History
Black American Culture & Heritage Community Culture & Heritage Historic Preservation +1 more

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,050,000
The NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01) invites applications for clinical trials focusing on complementary and integrative health approaches. This funding opportunity emphasizes the importance of multisite feasibility trials to gather essential data for planning future efficacy studies. Deadlines for standard and AIDS-related applications range from February 2024 to November 2026, underscoring the urgency for innovative research in high-priority areas.
Integrative & Alternative Health

Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required) (351620)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites applications for investigator-initiated clinical trials focused on complementary and integrative health interventions delivered remotely or via mobile health technologies. The trials must be fully powered, with no in-person contact, and require justification for this approach. Preliminary data on feasibility and safety must be provided, alongside evidence of clinical benefit. A Plan for Enhancing Diverse Perspectives is mandatory for submission. Key deadlines range from February 2024 to June 2026.
Integrative & Alternative Health Telemedicine & Telehealth

Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The Feasibility Clinical Trials of Mind and Body Interventions (R34) program seeks to support trials focused on complementary health approaches for conditions identified as high-priority by NCCIH. This funding opportunity aims to gather essential data necessary for planning future clinical efficacy studies. Applicants must demonstrate the feasibility of interventions and their potential impact on public health. Contacting NCCIH scientific contacts before submission is encouraged, and a Plan for Enhancing Diverse Perspectives is required.
Integrative & Alternative Health

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) (351647)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH StrokeNet initiative invites applications for multi-site exploratory and confirmatory clinical trials targeting interventions for stroke prevention, treatment, and recovery. This includes biomarker validation studies and ancillary studies to enhance active research. Successful applicants will collaborate within the NIH StrokeNet framework, with support from the National Coordinating Center and Data Management Center to ensure efficient study implementation and robust statistical analysis. Key deadlines for application submissions span from March 2024 to November 2026.
Stroke

NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional) (351679)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The NIDA Mentored Clinical Scientist Development Program Award aims to foster research independence in clinician scientists by providing intensive supervised research training and career development in the field of substance use and substance use disorder. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submission for this essential funding opportunity.
Addiction & Substance Use Disorders Medical Education & Professional Training Drug Use Disorder

Traditional Fine Arts Organization Grant

Traditional Fine Arts Organization Inc
Private
United States
US $1,000 - US $5,000
The Traditional Fine Arts Organization Grant aims to support art museums and cultural centers in promoting American representational art through co-sponsorship of exhibitions. The grant encourages institutions to provide detailed information about their exhibitions online and to make catalogs freely available. Grants are available for exhibits opening through mid-2025, fostering education and appreciation of art while avoiding funding for capital improvements or operating expenses.
American Art

Cigarette Litter Prevention Program (CLPP) Grants

Keep America Beautiful (KAB)
Private
United States
US $5,000 - US $20,000
The Cigarette Litter Prevention Program (CLPP) Grants, offered by Keep America Beautiful, aim to significantly reduce cigarette waste in public spaces across the U.S. since 2003. The program has successfully implemented strategies in over 1,800 communities, achieving an average 50% reduction in litter. Eligible applicants include KAB affiliates and local organizations focused on recycling and public education. Priority is given to partnerships and projects that expand the program's reach, especially those targeting clean water initiatives.
Recycling Waste Management Environmental Contamination & Pollution

Greatest American Cleanup Grants

Keep America Beautiful (KAB)
Private
United States
Up to US $5,000
The Great American Cleanup Grants, offered by Keep America Beautiful, aim to enhance community beautification and environmental efforts across the U.S. This initiative encourages KAB affiliates to remove litter, plant greenery, and restore public spaces, contributing to the larger goal of cleaning up 25 billion pieces of litter by 2026. With cash grants available, this program fosters collaboration among communities, promoting sustainable practices and a cleaner, greener future for all.
Recycling Environmental Contamination & Pollution Waste Management +5 more

Martin Luther King Jr. (MLK) Corridor Community Grants

Keep America Beautiful (KAB)
Private
United States
US $5,000 - US $20,000
The Martin Luther King Jr. (MLK) Corridor Community Grants, provided by Keep America Beautiful, aim to empower communities to revitalize and beautify MLK corridors across the U.S. These grants support various projects, including murals, community gardens, and cleanup efforts, contributing to the initiative's goal of beautifying 25,000 communities by 2026. Eligible applicants include nonprofits, local governments, and community organizations, with a focus on sustainable impacts and local engagement.
Community Development & Revitalization Greening & Beautification Public / Community Art +1 more

Drug Discovery Faculty Starter Grant

Pharmaceutical Research And Manufacturers Of America Fnd Inc (PhRMA)
Private
United States
US $100,000
The Drug Discovery Faculty Starter Grant, offered by the PhRMA Foundation, supports early-career researchers in drug discovery at U.S. universities. With a funding amount of $100,000 for one year, this grant is targeted at faculty members within five years of their independent status. The program aims to foster innovative research that integrates various scientific disciplines, ultimately leading to novel treatments for patients. Eligibility extends to full-time faculty members eligible for promotion.
Pharmacology

Freeman Hrabowski Scholars Program

Howard Hughes Medical Institute
Private
United States
Unspecified amount
The Freeman Hrabowski Scholars Program, funded by the Howard Hughes Medical Institute, supports exceptional scientists for a five-year term, with potential for renewal. Scholars receive up to $8.6 million over ten years, including salaries, benefits, and a substantial research budget. They dedicate at least 80% of their time to research and foster an inclusive lab environment, mentoring future scientists. This program emphasizes scientific excellence while integrating diversity, equity, and inclusion into research practices.
Biology Diversity, Equity & Inclusion Science +2 more

Professional Grants Program - General Grant Category

National Athletic Trainers Assn Research & Education Foundation
Private
United States
Up to US $50,000
The NATA Foundation, established in 1991, is dedicated to advancing the athletic training profession through research and education. It offers the Professional Grants Program to support exceptional research projects relevant to athletic training. With a funding limit of $50,000 over three years, the program encourages diverse proposals, ensuring that the primary or co-primary investigator is a BOC certified athletic trainer. This initiative aims to enhance the profession and benefit the broader physically active community.
Kinesiology & Sports Medicine

NATA: Professional Grants Program - New Investigator Grant

National Athletic Trainers Assn Research & Education Foundation
Private
United States
Up to US $20,000
The NATA Foundation's Professional Grants Program - New Investigator Grant offers up to $20,000 in funding for innovative research projects in athletic training. This program is aimed at supporting new investigators who are NATA members and BOC certified athletic trainers. The grant fosters research that enhances the profession and contributes to the health and safety of physically active individuals, promoting evidence-based practices in athletic training.
Kinesiology & Sports Medicine

Innovations in Graduate Education (IGE) Program (351947)

National Science Foundation (NSF)
Federal Government
United States
US $300,000 - US $1,000,000
The Innovations in Graduate Education (IGE) Program, funded by the National Science Foundation, aims to transform STEM graduate education through innovative training approaches. It encourages proposals that support skill development for STEM careers and research on effective educational systems. The program offers funding for projects that pilot and validate novel educational models, promoting broad participation and collaboration with various sectors. Awards range from $300,000 to $1,000,000, depending on the track and project duration.
STEM / STEAM Education

NATA: Doctoral Student Grants Program

National Athletic Trainers Assn Research & Education Foundation
Private
United States
Up to US $2,500
The NATA Doctoral Student Grants Program, offered by the National Athletic Trainers’ Association Foundation, provides financial support for innovative research projects in athletic training. Each year, multiple awards of up to $2,500 are available, with funding limited to direct costs over a maximum of one year. This initiative aims to enhance the profession through research, benefiting athletic trainers and the broader physically active community.
Kinesiology & Sports Medicine

NATA: Masters Student Grant Program

National Athletic Trainers Assn Research & Education Foundation
Private
United States
Up to US $1,000
The NATA Masters Student Grant Program, facilitated by the NATA Foundation, supports innovative research projects by master's students in athletic training. With a funding limit of $1,000 for one year, this program emphasizes ethical research practices and collaboration with faculty mentors. Eligible applicants must be current master's students and members of NATA. The foundation aims to enhance the athletic training profession through research and education, fostering growth and development in healthcare.
Kinesiology & Sports Medicine

Emergency Medicine Interest Group Grant (EMIG)

Society for Academic Emergency Medicine Foundation
Private
United States
Up to US $1,000
The Emergency Medicine Interest Group Grant (EMIG), funded by the Society for Academic Emergency Medicine Foundation, supports medical student interest groups in enhancing emergency medicine education. Grants of up to $500 are awarded for one year, with potential for renewal. Eligible applicants include established or developing EMIGs at medical schools, focusing on educational initiatives. This grant aims to foster innovation in teaching methodologies and support resources for students pursuing education in emergency medicine.
Emergency Medical Care & Services

GEMSSTAR for Emergency Medicine Supplemental Funding Program

Society for Academic Emergency Medicine Foundation
Private
United States
Up to US $25,000
The GEMSSTAR for Emergency Medicine Supplemental Funding Program provides up to $25,000 over two years to support emergency medicine physicians who have received the NIA GEMSSTAR grant. This program aims to enhance the Professional Development Plan of GEMSSTAR awardees, ensuring they receive the necessary funding for their research endeavors. Eligibility is limited to those who have completed their clinical specialty training and are based at U.S. institutions, with funding contingent upon available resources.
Emergency Medical Care & Services Aging / Gerontology Dental Health +2 more

ASTRO-BCRF Emerging Investigator Award

American Society For Radiation Oncology
Association/Society
United States
Up to US $100,000
The ASTRO-BCRF Emerging Investigator Award aims to support one early career researcher in breast radiation oncology from underrepresented populations. This initiative by the American Society for Radiation Oncology and the Breast Cancer Research Foundation provides $100,000 for direct costs over one year, emphasizing diversity in the scientific workforce and encouraging eligible individuals to self-identify as part of underrepresented groups in biomedical research.
Breast Cancer

ASTRO Residents/Fellows in Radiation Oncology Seed Grant

American Society For Radiation Oncology
Association/Society
United States
Up to US $50,000
The ASTRO Residents/Fellows in Radiation Oncology Seed Grant aims to advance the research careers of residents and fellows focusing on radiation oncology through funding basic, translational, and clinical research. It encourages innovative projects that enhance patient care and improve health care delivery, including cancer research and understanding radiation effects on tissues. This grant is supported by the American Society for Radiation Oncology, which seeks to foster impactful research in this vital medical field.
Cancer / Oncology

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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