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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,706 Results based on applied filters

The Applied Materials Momentum Fund - Last Mile Grants

Applied Materials Foundation
Corporate
United States
Up to US $10,000
The Applied Materials Momentum Fund is dedicated to enhancing educational opportunities for students in the semiconductor industry, particularly supporting women engineers. This initiative provides essential financial assistance through various grant types, including emergency mini-grants and larger Last Mile grants, aimed at helping students overcome financial barriers in their pursuit of degrees. By fostering diverse and resilient teams, the fund contributes to innovation and growth in technology and engineering fields.
Science Communications Physics Bioengineering +10 more

Boustany Foundation: Sport 4 Children Award

Boustany Foundation
Private
Austria, Belarus +29 more
Up to €50,000
The Boustany Foundation's Sport 4 Children Award aims to enhance children's lives through sports, fostering happiness, health, and social skills. Open to organizations globally, the award supports projects that utilize sports for children's well-being. With a funding of 50,000 Euros, it encourages innovative and inclusive initiatives that promote participation in sports, aiming to create positive behavioral changes and community engagement. The foundation believes in the transformative power of sports to build responsible and healthy adults.
Youth Services Sports & Athletics

The Amy Heryford Ousley and James Heryford Ousley Educational Fund

Amy Heryford Ousley And James Heryford Ousley
Private
United States
Unspecified amount
The Amy Heryford Ousley and James Heryford Ousley Educational Fund, established in 2005, provides scholarships to Klamath and Lake County students attending nonprofit colleges in the U.S. The fund, initially valued at $6.5 million, has awarded over $2.5 million in scholarships. Eligible students must have attended a Klamath County high school for four years, maintain a minimum GPA, and enroll as full-time students. Scholarships can reach up to $3,000 annually for up to five years.
Academic Scholarship Programs

Ameren Missouri Grant Program

Ameren Corporation
Corporate
Adair County, Missouri, Adams County, Illinois +149 more
Unspecified amount
The Ameren Missouri Grant Program supports local organizations and community events in Missouri and Illinois, enhancing the quality of life for residents. Grants vary in amount and are typically awarded during a mid-year cycle lasting 30 days. Eligible applicants must be nonprofits serving communities where Ameren operates, while ineligible entities include individuals and for-profit organizations. This initiative reflects Ameren's commitment to community development and engagement.
Education Economic Services & Development Civic Engagement & Education +1 more

Covista Foundation Grant

Adtalem Global Education Foundation
Private
United States
Unspecified amount
The Adtalem Global Education Foundation, established in 2010, is dedicated to enhancing education and community development. Based in Chicago, it focuses on expanding educational access, particularly for underrepresented minorities in the healthcare sector. The foundation prioritizes initiatives that promote economic growth through skills-based workforce development, address healthcare disparities, and increase access to quality education for underserved populations. Its commitment to civic engagement and equality reflects its mission to empower communities.
Health & Medicine Economic Services & Development Workforce Preparation & Job Readiness +3 more

Professional Pipeline Grant - American College of Bankruptcy (formerly Diversity, Equity and Inclusion Grant)

American College Of Bankruptcy Foundation
Private
United States
Up to US $15,000
The Professional Pipeline Grant from the American College of Bankruptcy Foundation aims to foster diversity in the insolvency industry. This grant supports legal services organizations working to create an inclusive pipeline for students and professionals facing barriers to success. With grants typically capped at $10,000, the Foundation may offer higher amounts for innovative new programs. Applicants are encouraged to utilize available resources to enhance their proposals and maximize funding opportunities.
Diversity, Equity & Inclusion Law Financial Literacy +1 more

Alzheimer’s Association: Center for Dementia Respite Innovation Grant (CDRI)

Alzheimer's Association
Private
United States
US $50,000 - US $100,000
The Alzheimer’s Association's Center for Dementia Respite Innovation Grant (CDRI) supports innovative respite care projects, aiming to improve person-centered dementia care across the U.S. With up to $20 million available over five years, the grant encourages local respite care providers to enhance their services through collaboration and innovative solutions. Recipients will receive training and assistance to ensure their programs are effective and sustainable, addressing the growing need for quality dementia care.
Dementia & Alzheimer’s Disease Caregiver Support / Respite Care

ISTAART Grant Program for Conferences and Convenings (IGPCC) Grant

Alzheimer's Association
Private
Algeria, Andorra +160 more
Up to US $20,000
The ISTAART Grant Program for Conferences and Convenings (IGPCC) Grant, funded by the Alzheimer's Association, aims to support innovative initiatives that enhance research discussions among Professional Interest Areas (PIAs). This funding mechanism encourages collaboration and networking opportunities for ISTAART members, allowing for the organization of educational workshops and conferences. Grants of up to $20,000 are available, with a focus on new projects that haven't received funding in the last 24 months. Applications are reviewed year-round.
Dementia & Alzheimer’s Disease

Alpha Delta Pi Foundation: Ronald McDonald House Charities (RMHC) Endowment

Alpha Delta Pi Foundation Inc
Private
Canada, United States
US $2,000 - US $10,000
The Alpha Delta Pi Foundation, a private funder, established the Ronald McDonald House Charities (RMHC) Endowment to support local RMHC Chapters in the U.S. and Canada that lack adequate backing from Alpha Delta Pi collegiate or alumnae associations. Since 1979, over $22 million has been contributed to RMHC, with grants ranging from $2,000 to $10,000 available for houses, renovations, and family room expansions, fostering a strong philanthropic partnership.
Real Estate & Housing

FSR Early Career Fellowship Grant

Foundation For Sarcoidosis Research
Private
United States
US $150,000
The FSR Early Career Fellowship Grant supports early-stage researchers in sarcoidosis, fostering skills and knowledge advancement. With $150,000 over two years, this grant aims to enhance medical care and scientific understanding of the disease. Eligible applicants, including international candidates, must present innovative study proposals and demonstrate a commitment to sarcoidosis research. FSR encourages transitions from fellowships to faculty positions, thereby strengthening academic credentials and promoting impactful research contributions.
Respiratory Diseases & Systems Immune System Diseases

Watson-Brown Foundation Scholarship

Watson Brown Foundation Inc
Private
United States
Up to US $3,000
The Watson-Brown Foundation Scholarship offers need and merit-based financial assistance to students from Georgia and South Carolina attending accredited four-year colleges. Established in 1970, the foundation aims to enhance educational opportunities for underprivileged youth, awarding over $2.4 million annually. Eligible students can receive up to $3,000 per semester to cover educational expenses, supporting their academic journey while encouraging responsible scholarship and historic preservation.
Education - Higher Education

National Scleroderma Foundation: New Investigator Grant

National Scleroderma Foundation
Private
United States
Up to US $200,000
The National Scleroderma Foundation's New Investigator Grant aims to support emerging researchers dedicated to scleroderma studies. This three-year grant, totaling $200,000, encourages applicants with doctoral degrees and postdoctoral experience. Eligible candidates are invited to submit proposals that may lead to further research funding. The grant emphasizes innovative research approaches while providing essential financial support for early-career investigators. Note that the grant does not cover certain costs, ensuring focused investment in research advancement.
Immune System Diseases Rare Diseases

Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant

National Scleroderma Foundation
Private
United States
US $200,000
The Scleroderma-Related Lung Disease— The Debra Lurvey Memorial Research Grant, provided by the National Scleroderma Foundation, aims to support research in scleroderma-related lung disease. With a funding amount of $200,000, the grant encourages established investigators to explore innovative solutions and enhance understanding of this condition, ultimately working towards improving the quality of life for affected individuals and advancing medical knowledge in the field.
Rare Diseases Immune System Diseases Interstitial Lung Disease

National Scleroderma Foundation: Pediatric Scleroderma

National Scleroderma Foundation
Private
United States
Up to US $500,000
The National Scleroderma Foundation supports pediatric scleroderma research with up to $500,000 in funding for new and established investigators. Their mission focuses on advancing medical research and promoting awareness of scleroderma, with the vision of improving the lives of those affected. This initiative aims to encourage innovative research that could lead to better treatments and a potential cure for pediatric scleroderma, enhancing support for affected families.
Rare Diseases Immune System Diseases Children’s Health & Pediatrics

Blue Meridian Partners Grant

Blue Meridian Partners Inc
Private
United States
Unspecified amount
Blue Meridian Partners Grant aims to transform lives of young people and families in poverty by investing in scalable strategies that enhance economic and social mobility. The organization seeks stand-alone nonprofits with a proven track record, a compelling vision, and strong leadership. With a commitment to performance-based investing, Blue Meridian provides significant capital, often exceeding $100 million, to foster impactful solutions and address pressing social challenges effectively.
Economic Services & Development Poverty Alleviation & Services Youth Services +3 more

EmpowHer Grants

Boundless Futures Foundation
Private
United States
Up to US $50,000
EmpowHer Grants, offered by the Boundless Futures Foundation, provide essential financial support and resources to female entrepreneurs in the U.S. who are committed to creating social impact through their businesses. Grants, which can go up to $25,000, are available to those with businesses that are less than three years old and demonstrate revenue generation. This initiative aims to empower women by reducing barriers and fostering a supportive entrepreneurial community.
Entrepreneurship Business Development

Corporate Giving Program: Health Equity in Cardiovascular Disease Grant

Cytokinetics
Association/Society
United States
Up to US $20,000
The Corporate Giving Program by Cytokinetics focuses on health equity in cardiovascular disease, targeting underserved communities. It seeks to fund initiatives that address disparities in healthcare access, including public health campaigns, community support programs, and innovative solutions. Eligible organizations must be 501(c)(3) nonprofits in the U.S. that align with these goals, ensuring that no direct healthcare practice involvement occurs. This initiative aims to foster equitable health outcomes and enhance community well-being.
Cardiovascular Diseases & Systems Epidemiology & Public Health

Emily Stover Memorial Scholarship

Community Foundation for Nantucket
Private
United States
US $1,000 - US $10,000
The Emily Stover Memorial Scholarship offers $2,000 annually to support outstanding members of the Nantucket community. This scholarship is aimed at individuals who are dedicated to helping others and are pursuing careers that reflect this commitment. Eligible applicants must be Nantucket residents attending accredited colleges or universities, demonstrating a passion for community service and a desire to make a positive impact.
Academic Scholarship Programs

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative: Pain Research Enhancement Program (PREP) supports R15-eligible Principal Investigators in conducting innovative pain research. This program encourages interdisciplinary partnerships and aims to enhance the research environment for health professional trainees. Key application deadlines include November 19, 2024, and October 28, 2025, with specific dates for AIDS-related applications. By fostering collaboration, the initiative seeks to advance understanding and treatment of pain.
Chronic / Acute Pain Drug Use Disorder Anesthesia and Pain Medicine

Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to foster the development of American Indian and Alaska Native scientists by funding eligible Tribal Entities. This initiative focuses on creating effective training and mentoring activities for individuals pursuing doctoral degrees in biomedical research. Ultimately, it seeks to enhance the capability of researchers to address health disparities within AI/AN communities, ensuring culturally appropriate and ethically responsible research practices.
Indigenous Health Systems Native American Services Medical Education & Professional Training +1 more

Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program aims to support federally recognized AI/AN Tribes and organizations in developing a workforce of researchers focused on AI/AN health disparities. This initiative, funded by the NIH, provides phased support for training and mentoring activities that equip individuals with the necessary skills to conduct culturally responsible biomedical research, ultimately guiding them towards successful careers in the biomedical research field.
Indigenous Health Systems Native American Services Biology +2 more

Wexner Field Fellowship

Wexner Family Charitable Fund
Private
North America
Unspecified amount
The Wexner Field Fellowship is a three-year program aimed at enhancing the leadership skills of Jewish professionals in North America. Participants engage in leadership institutes, receive personalized coaching, and gain access to professional development funds. This fellowship fosters a robust network of leaders committed to serving the Jewish community, encouraging a deeper understanding of its diversity and strengthening essential leadership competencies. Eligible candidates must be full-time employees at Jewish organizations with at least five years of relevant experience.
Jewish Culture Civic Leadership Development

Wexner Davidson Fellowship

Wexner Family Charitable Fund
Private
Canada, Mexico +1 more
Unspecified amount
The Wexner Davidson Fellowship (WDF) is a transformative leadership development program designed for Jewish communal professionals in North America aged 26-36. Over three years, Fellows engage in cohort-based learning at biannual institutes, receive coaching, and deepen their Jewish knowledge while building a strong professional network. This initiative fosters personal and professional growth, equipping the next generation of leaders to serve their communities effectively and connect with a global alumni network.
Jewish Culture Judaism

NCB - Botany Research Scholarship Program

Northern California Botanists
Association/Society
United States
US $1,500
The NCB - Botany Research Scholarship Program, offered by Northern California Botanists, targets undergraduate and graduate students pursuing research in botany and plant ecology. Scholarships of $1,500 support independent study, thesis, or dissertation projects within a specific geographic area of Northern California. Eligible applicants may reapply for funding for up to four years. This initiative aims to foster academic careers in botany and promote valuable ecological research.
Plant Science Ecology Botanical Conservation

Clinical and Translational Science Award (UM1 Clinical Trial Optional) (356316)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $6,500,000
The Clinical and Translational Science Award (CTSA) Program invites applications to enhance clinical and translational science through innovative partnerships and research programs. This initiative aims to accelerate the delivery of treatments to diverse populations by improving clinical research efficiency, creating national resources for public health responses, and providing training for clinical research professionals. Applications are due by 5:00 PM local time, with optional Letters of Intent recommended 30 days prior to the full proposal deadline.
Science Health & Medicine Epidemiology & Public Health +1 more

NIA Advanced Postdoctoral Career Transition Awards to Promote Diversity in Translational Research for AD/ADRD (K99/R00 Clinical Trial Not Allowed) (356315)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Approximately US $100,000
The NIA Advanced Postdoctoral Career Transition Awards aim to enhance diversity in the translational research workforce for Alzheimer's disease and related dementias (AD/ADRD). This initiative supports early career researchers from diverse backgrounds in acquiring essential research skills applicable to various AD/ADRD studies. The goal is to cultivate a more diverse pool of researchers capable of leading interdisciplinary approaches in treatment, prevention, and management of AD/ADRD. Notably, independent clinical trials are not permitted under this award.
Dementia & Alzheimer’s Disease Diversity, Equity & Inclusion Medical Education & Professional Training

Union Home Foundation Grant

The Union Home Foundation Inc
Private
Ada County, Idaho, Aiken County, South Carolina +183 more
More than US $1,000
The Union Home Foundation Grant provides financial support to nonprofit organizations that promote economic self-sufficiency through financial literacy and housing initiatives. Established in 2015, this grant has awarded over $2 million to various nonprofits across the U.S. Grants typically start at $1,000 and are available for a one-year period. Organizations must be 501(c)(3) tax-exempt and can only apply once per year, following specific eligibility criteria.
Financial Literacy Equitable & Affordable Housing Supportive Housing & Shelters

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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