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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,706 Results based on applied filters

Pediatric Lupus Research Grant

Lupus Foundation Of America Inc
Private
Canada, United States
Up to US $45,000
The Pediatric Lupus Research Grant aims to provide pilot funding for innovative research initiatives focusing on pediatric systemic lupus erythematosus (SLE). It supports various projects, including feasibility studies and the development of new methodologies or technologies. With a total funding of up to $90,000 for two projects over one year, this grant encourages collaborations and aims to significantly improve the lives of children affected by lupus in the U.S. and Canada.
Lupus Children’s Health & Pediatrics

Cystic Fibrosis Foundation: Postdoctoral Research Fellowship Award

Cystic Fibrosis Foundation
Private
United States
Up to US $151,000
The Cystic Fibrosis Foundation offers Postdoctoral Research Fellowship Awards to support research training in cystic fibrosis. The program provides up to $66,000 in salary support for the first year and $67,000 for the second year, along with $9,000 for research and travel expenses. Applicants focusing on CFTR protein function restoration or gene correction strategies are encouraged to apply. Open to U.S. citizens and residents, preference is given to recent graduates beginning their research careers.
Cystic Fibrosis

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The Academic Research Enhancement Award (AREA) supports small-scale research grants at institutions with limited NIH funding, enhancing undergraduate biomedical research experiences. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This funding opportunity encourages institutions to foster research environments that benefit undergraduate students while addressing significant NIH research interests through minimal risk clinical trials.
Biology Health & Medicine Diseases & Conditions +1 more

PVA Research Grants & Fellowships

Paralyzed Veterans of America
Private
Canada, United States
Up to US $200,000
The Paralyzed Veterans of America Research Foundation offers grants and fellowships aimed at enhancing the quality of life for individuals with spinal cord injuries and diseases. With a history of funding over $54 million since 1976, the foundation supports innovative research across categories like Basic Science, Clinical Applications, Design & Development, and Fellowships. Grants can reach up to $200,000, fostering advancements in medical technologies and training for future experts in spinal cord research.
Spinal Cord Injuries

Deems Taylor/Virgil Thomson Awards

Ascap Foundation
Private
District of Columbia, Puerto Rico +1 more
Up to US $4,000
The Deems Taylor/Virgil Thomson Awards, established in 1967 by the ASCAP Foundation, honor exceptional books, articles, and liner notes about music. With total prizes of $4000, awards are given to top submissions in Pop and Concert Music genres. Eligible works must be published in the previous year and meet specific criteria. The foundation aims to celebrate the legacy of Deems Taylor and Virgil Thomson, prominent figures in American music history.
Music

Jay Gorney Award

Ascap Foundation
Private
District of Columbia, Puerto Rico +1 more
US $2,500
The ASCAP Foundation's Jay Gorney Award honors songwriters who create original music with socially conscious themes. Established in 2009, this award commemorates composer Jay Gorney's legacy, particularly his iconic song 'Brother, Can You Spare a Dime?' Entrants are judged on their ability to convey powerful messages through artistry and lyrical excellence. The award includes a $1,000 monetary prize, fostering creativity and social awareness in the music community.
Music

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $130,000
The Mentored Career Development Award (K01) from the NIH aims to diversify the biomedical research workforce by supporting candidates from underrepresented backgrounds. It provides mentoring and training in research independence, focusing on cardiovascular, pulmonary, hematologic diseases, and sleep disorders. Eligible institutions can guide faculty members in special studies, but applicants should not lead their own clinical trials. This initiative promotes diversity and enhances research capability in health disparities populations.
Cardiovascular Diseases & Systems Hematological Systems Respiratory Diseases & Systems +2 more

Research Foundation of the ASCRS: Career Development Award

The American Society Of Colon & Rectal Surgeons
Private
Canada, United States
US $150,000
The Research Foundation of the American Society of Colon and Rectal Surgeons offers a Career Development Award to support early career investigators in colorectal surgery. With a funding of $75,000 per year for two years, this award emphasizes mentorship and career growth. Applicants must be within five years of their first faculty position and demonstrate innovative research in colon and rectal diseases. The award aims to enhance academic careers while fostering advancements in surgical techniques.
Colon Cancer Digestive System Health & Diseases

Robotic Research Grant

The American Society Of Colon & Rectal Surgeons
Private
Canada, United States
US $150,000
The Robotic Research Grant, offered by the American Society of Colon and Rectal Surgeons, provides up to $150,000 over two years for innovative research in colorectal surgery and robotics. Emphasizing education, health equity, and novel techniques, the grant supports projects conducted in the U.S. or Canada, with a focus on scientific rigor. Applications must be submitted by ASCRS members who are principal investigators, ensuring alignment with ethical research standards.
Digestive System Health & Diseases Colon Cancer

Special Emphasis Limited Project Grant: Colorectal Surgery and Health Equity

The American Society Of Colon & Rectal Surgeons
Private
Canada, United States
Up to US $20,000
The Special Emphasis Limited Project Grant from the American Society of Colon and Rectal Surgeons aims to address health disparities in colorectal surgery. It focuses on improving care for racial/ethnic minorities, women, LGBTQ+ populations, and individuals with disabilities. Proposals should concentrate on patient-oriented interventions and may explore quality improvement, access to services, and enhancing workforce diversity. Funding of up to $20,000 is available for innovative projects that promote equity in colorectal healthcare.
Digestive System Health & Diseases Colon Cancer Health Care Access & Delivery +1 more

John and Marlene Heslip Architecture Student Scholarship Program

CONCRETE MASONRY AND HARDSCAPES ASSOCIATION
Private
Canada, United States
US $5,000
The John and Marlene Heslip Architecture Student Scholarship Program supports full-time undergraduate and graduate architecture students at accredited institutions in the U.S. and Canada. With a focus on innovative design using manufactured concrete masonry and hardscape products, the program awards a $5,000 scholarship each academic year. The scholarship aims to advance the education of future architects while fostering a commitment to excellence and diversity in the field.
Architecture

Concrete Advancement Foundation Grant

Concrete Advancement Foundation Inc
Private
United States
Unspecified amount

Concrete Advancement Foundation

Vision

To be the resilient resource to collaboratively support concrete as the leading sustainable building material.

Goals

  • Goal 1: To fund and manage highly credible and impactful research to achieve societal goals
    • Decarbonization
    • Resilient, sustainable and affordable communities
    • World-class sustainable infrastructure
  • Goal 2: Disseminate knowledge and create educational tools for the benefit of stakeholders
    • Attract and advance the concrete industry workforce
    • Tools and programs to advance communities and societal goals
  • Goal 3: To be the resilient resource for collaboratively funding the advancement of the concrete industry
    • Bring together industry stakeholders to provide the financial resources and governance needed to accomplish the Foundation's goals
    • Measure progress and success of the Foundation goals and ensure strategic, long-term alignment and communication with stakeholder audiences

Funding

The Foundation funds research and education programs that are consistent with our mission of increasing the quality, professionalism and sustainability of the ready mixed concrete industry.

Those wishing to perform research on concrete materials topics may consult the list of research needs developed by NRMCA's Research Engineering & Standards Committee. Please note that this list is only a guide, and neither guarantees funding of a particular topic, nor precludes research on topics not listed.

Engineering Civil Engineering Materials Science and Engineering

Bristol Bay Foundation: Higher Education Scholarship Program

Bristol Bay Foundation
Private
United States
Unspecified amount
The Bristol Bay Foundation offers a Higher Education Scholarship Program supporting both full-time and part-time students pursuing 4-year or advanced degrees. Eligible applicants must be shareholders of the BBNC or their descendants, have a high school diploma or GED, and maintain a minimum GPA of 2.0. Scholarships are based on academic performance and life experiences, with applications due in April for the next academic year.
Education - Higher Education

Career-Focused Vocational Education (CFVE) Scholarship Program

Bristol Bay Foundation
Private
United States
Unspecified amount
The Career-Focused Vocational Education (CFVE) Scholarship Program supports Bristol Bay Native Corporation shareholders and their descendants in pursuing vocational training for careers such as piloting, maritime, and cosmetology. This initiative emphasizes cultural heritage and aims to enhance long-term employment opportunities in the Bristol Bay region of Alaska. Eligible applicants must have a high school diploma and maintain a minimum GPA of 2.0 while enrolled in an approved program.
Vocational & Trade Education

Grassroots Grants Program (GGP)

American Golf Industry Coalition
Association/Society
United States
Unspecified amount
The Grassroots Grants Program (GGP) aims to enhance participation in golf among underrepresented communities, including racial minorities, women, and veterans. Launched in May 2021, it has awarded $1.8 million to 155 organizations, promoting diversity, equity, and inclusion in the sport. The program supports tax-exempt organizations focused on self-sustainability and offers funding for golf instruction, equipment, and access to facilities. Priority is given to those not receiving substantial backing from major golf organizations.
Diversity, Equity & Inclusion Golf

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This grant opportunity aims to reduce sleep health disparities through non-pharmacological interventions. It supports research that examines sleep as a modifiable factor influencing health outcomes among populations facing health disparities. The initiative highlights the importance of promoting sleep health in various communities, ensuring equitable access to resources and interventions. Deadlines for applications span from October 2024 to June 2027, allowing multiple opportunities for researchers to apply and contribute to this vital area of health research.
Sleep Health Disparities & Social Determinants of Health

The NCI Worta McCaskill-Stevens Career Development Award for Community Oncology and Prevention Research (K12 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $3,750,000
The NCI Worta McCaskill-Stevens Career Development Award supports new clinicians committed to research in community oncology and cancer prevention. This funding aims to facilitate their transition to independent research careers and advanced funding mechanisms. Scholars can lead independent community-based clinical trials, conduct ancillary studies, or gain valuable research experience, specifically targeting underserved communities. Applications are due by 5:00 PM local time of the applicant's organization.
Cancer / Oncology Medical Education & Professional Training

Roots & Shoots Project Grant

Jane Goodall Institute For Wildlife Research Education & Conservation
Private
United States
US $500
The Roots & Shoots Project Grant, offered by the Jane Goodall Institute, empowers U.S.-based youth to initiate community-action projects that positively impact people, animals, and the environment. With a funding opportunity of $250, this grant encourages young leaders to take charge and make a difference in their communities. Eligible applicants include children, teens, educators, and community groups. Join the movement to foster change and celebrate local initiatives that contribute to a sustainable future.
Community Services Environment

Maria and Paolo Alessio Southern Italy Scholarship

UNICO Foundation Inc
Association/Society
United States
US $2,500
The Maria and Paolo Alessio Southern Italy Scholarship, offered by the UNICO Foundation, supports students of Southern Italian descent pursuing a degree at an accredited U.S. college or university. Valued at $2,500, this scholarship aims to empower students who demonstrate academic excellence with a minimum GPA of 2.7. Eligible applicants must be U.S. citizens and can be Freshmen, Sophomores, or Juniors, continuing their studies in the 2026-2027 academic year.
Education - Higher Education Academic Scholarship Programs

Cancer Research & Prevention Grant

UNICO Foundation Inc
Association/Society
United States
Unspecified amount
The UNICO Foundation Inc. offers the Cancer Research & Prevention Grant to support vital research projects addressing various types of cancer, including colon, breast, and prostate cancer. Established in 1962, this non-profit organization aims to enhance lives through charitable contributions and educational initiatives. Grants are exclusively for direct research and preventive measures, ensuring that all funds are utilized effectively. This initiative reflects UNICO's commitment to combating cancer and its impact on individuals and families across the United States.
Cancer / Oncology

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required) (353709)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Quantitative Research Development Award (K25) aims to attract researchers in quantitative science and engineering to focus on NIH-relevant health research. This award provides protected time for supervised study and research, allowing professionals from fields like mathematics, statistics, and engineering to integrate their expertise into health-related studies. The K25 is specifically for lead investigators of independent clinical trials or related studies, fostering innovation in clinical research and career development.
Engineering Mathematics Chemistry +9 more

Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) (353711)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Quantitative Research Development Award (K25) aims to engage skilled professionals in NIH-relevant research, enhancing their expertise in addressing health-related issues. This award supports individuals with backgrounds in quantitative sciences and engineering, providing them with dedicated time for supervised research and study. Key application deadlines span from June 2024 to February 2027, emphasizing the program's commitment to fostering innovative research in health and disease.
Engineering Mathematics Chemistry +8 more

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed) (353710)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Quantitative Research Development Award (K25) aims to attract researchers with quantitative science backgrounds to NIH-relevant studies. It provides support and protected time for professionals to integrate their expertise in areas like mathematics and statistics with health research. Notably, it does not support independent clinical trials, focusing instead on collaborative experiences under mentorship. The application process involves specific deadlines for submissions, including standard, renewal, and AIDS-related grants, encouraging diverse participation in significant health research.
Mathematics Chemistry Physics +8 more

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required) (353749)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Research Scientist Development Award (K01) aims to support emerging scientists by providing protected time for career development in biomedical, behavioral, or clinical sciences. This award, effective for three to five years, encourages research independence and may be beneficial for those transitioning fields or returning from a hiatus due to personal circumstances. Deadlines for applications vary, with important dates set for standard, renewal, and AIDS-related submissions.
Medical Education & Professional Training Science Health & Medicine +1 more

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) (353751)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Research Scientist Development Award (K01) supports early-career scientists with up to five years of protected time for intensive research training in biomedical, behavioral, or clinical sciences. This award is tailored for those pursuing independence in research and is particularly beneficial for individuals transitioning fields or returning from a hiatus. Importantly, applicants must not lead independent clinical trials but may participate in trials overseen by mentors.
Medical Education & Professional Training Science Health & Medicine +1 more

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) (353745)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH Mentored Clinical Scientist Research Career Development Award (K08) aims to develop the research careers of individuals with clinical doctoral degrees. This program provides essential support and protected time for intensive, supervised research experiences in biomedical and behavioral fields, including translational research. Important deadlines for applications span from June 2024 to February 2027, accommodating various grant types, including standard and AIDS-related applications.
Medical Education & Professional Training Science Health & Medicine +1 more

Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) (353747)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Clinical Scientist Research Career Development Award (K08) supports individuals with clinical doctoral degrees to develop their research careers in biomedical and behavioral fields. This program emphasizes a structured mentoring approach, aiming to address the nation's health-related research needs. Key application deadlines include June 12, 2024, and October 12, 2024, among others, providing opportunities for both new and renewal submissions.
Medical Education & Professional Training Biology Health & Medicine

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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