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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,709 Results based on applied filters

Life Comes From It (LCFI) Grants

Tides Foundation
Private
United States
Unspecified amount
The Life Comes From It Grant, funded by the Tides Foundation, supports grassroots initiatives focused on restorative, transformative, and indigenous justice. It prioritizes projects led by communities of color, emphasizing alternatives to incarceration and community-led solutions. Applicants must be 501c3 organizations based in the United States. This grant fosters a collaborative approach to healing and justice, aiming to shift power dynamics and promote inclusive practices across generations.
Indigenous Sovereignty & Rights Minority Services Racial / Ethnic Justice & Rights +1 more

Wabtec Direct Grant Program

Wabtec Foundation
Corporate
Ada County, Idaho, Alamance County, North Carolina +70 more
US $1,000 - US $10,000
The Wabtec Direct Grant Program focuses on creating sustainable impacts in local communities by funding 501(c)(3) non-profit organizations. Emphasizing education and environmental stewardship, the program supports initiatives that improve literacy, academic outcomes, and workforce readiness. Grants range from $1,000 to $10,000, prioritizing organizations that engage local Wabtec employees in volunteerism. The program promotes equitable access and non-discrimination while ensuring measurable results in funded projects.
All fields of work Literacy Academic Success & Enrichment +10 more

Humanity United Grant

Humanity United
Private
Asia, Colombia +3 more
Approximately US $150,000
The Humanity United Grant focuses on addressing human exploitation and violent conflict through a strategic approach. It emphasizes support for registered charities and initiatives globally, particularly in regions like Asia-Pacific and South Sudan. The grant fosters collaboration among partners to promote human dignity, racial justice, and peacebuilding. Interested organizations are encouraged to align their proposals with the outlined themes and engage with the funder for potential support.
Public Policy Journalism International / Foreign Affairs +5 more

NAAF Grant - General

Native American Agriculture Fund
Private
United States
Unspecified amount
The Native American Agriculture Fund (NAAF) offers grants to support Native farmers and ranchers through business assistance, agricultural education, technical support, and advocacy services. Established from the Keepseagle v. Vilsack settlement, NAAF is committed to providing essential resources to eligible organizations, including 501(c)(3) nonprofits, educational institutions, and tribal governments. Special focuses include inflation assistance and market access, ensuring a holistic approach to agricultural support.
Livestock & Ranching Farms & Farming Indigenous Sovereignty & Rights +1 more

SC Ministry Foundation: Annual Grants

SC Ministry Foundation
Private
United States
Unspecified amount
The SC Ministry Foundation provides annual grants aimed at supporting nonprofit organizations aligned with the mission of the Sisters of Charity of Cincinnati. These grants can be used for core programs, planning, and program expansion. Eligible organizations must demonstrate financial sustainability and avoid duplication of services. The application process starts with a pre-application survey, and funding decisions are typically made by June 30. Priority is given to projects in education, healthcare, and social services.
Social Justice / Human Rights Education Health Care Access & Delivery +2 more

Youth Programming Grant

Native American Agriculture Fund
Private
United States, United States Minor Outlying Islands
Unspecified amount
The Youth Programming Grant, offered by the Native American Agriculture Fund (NAAF), aims to support Native American farmers and ranchers through various projects. This grant focuses on providing essential business assistance, agricultural education, and advocacy services. By funding diverse initiatives, the NAAF seeks to promote the ongoing involvement of Native communities in agriculture, ensuring their sustainable growth and development within the sector.
Agricultural Education

Emerging Leader Award

The Mark Foundation for Cancer Research
Private
Canada, United States
US $1,000,000
The Mark Foundation Emerging Leader Award supports innovative cancer research led by early career investigators. Aimed at high-impact, high-risk projects, this grant is available to those employed by U.S. or Canadian non-profit academic institutions. Eligible applicants must be within three to eight years of starting their independent faculty research appointment. This award emphasizes multi-year independent funding and is not intended as the main funding source for the laboratory, ensuring that diverse research efforts are encouraged.
Cancer / Oncology

Disability Foundation Grants

The Dayton Foundation
Private
United States
Up to US $10,000
The Disability Foundation, in partnership with The Dayton Foundation, invites proposals for grants aimed at supporting organizations providing direct services to individuals with disabilities. Eligible applicants include community-based nonprofits and academic institutions. Grants, capped at $10,000, can be used for various purposes such as enhancing service accessibility, purchasing necessary equipment, and expanding services. This initiative seeks to empower disabled individuals by ensuring they receive essential resources and support.
Disability Care & Services Disaster Relief / Humanitarian Aid

NIHCM: Research Grants

The National Institute for Health Care Management
Private
United States
US $50,000 - US $60,000
The NIHCM Foundation is seeking innovative research proposals that address critical issues in U.S. health care, particularly focusing on drug pricing, provider consolidation, health care delivery, chronic disease management, and the role of artificial intelligence. Projects should aim to improve affordability and quality of care. We welcome submissions from a variety of researchers and organizations, with a preference for studies that can be completed within one year.
Health Policy & Advocacy Health Care Access & Delivery Health Disparities & Social Determinants of Health +4 more

NIHCM: Journalism Grants

The National Institute for Health Care Management
Private
United States
Unspecified amount
The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.
Journalism Health Information Technology Health Policy & Advocacy +5 more

SFP: Changemakers in Family Planning Grant Program

Society Of Family Planning Research Fund
Private
American Samoa, Guam +4 more
Unspecified amount
The Changemakers in Family Planning Grant Program aims to address institutionalized racism in the field of family planning by providing essential support to scholars of color. Recognizing that diversity and equity are crucial for advancing research in abortion and contraception, this initiative seeks to foster an inclusive community that empowers underrepresented voices in science. The Society of Family Planning is dedicated to creating a just environment where all scholars can contribute to meaningful advancements in family planning research.
Reproductive Health Reproductive Rights Reproductive Education

SFP: Emerging Scholars in Family Planning Grant

Society Of Family Planning Research Fund
Private
United States
Up to US $7,500
The Emerging Scholars in Family Planning Grant, offered by the Society of Family Planning, aims to support early-career researchers in developing a family planning research portfolio. This grant provides funding for publishable scholarly research projects, including thesis or dissertation work, fostering the next generation of scholars in abortion and contraception research. By promoting diversity and inclusion, the grant seeks to build a multidisciplinary community dedicated to advancing family planning science.
Reproductive Education Reproductive Health Reproductive Rights

Robert and Joan Dircks Foundation Grant Program

Robert & Joan Dircks Foundation
Private
United States
US $1,000 - US $15,000
The Robert and Joan Dircks Foundation Grant Program supports non-profit organizations in New Jersey that provide opportunities for disadvantaged individuals. With grants ranging from $1,000 to $15,000, the foundation focuses on innovative programs that solve critical issues rather than operational needs. Eligible organizations must be tax-exempt under section 501(c)(3) of the Internal Revenue Code. The foundation does not fund political activities, cultural projects, or operating budgets, ensuring resources directly benefit those in need.
Children With Disabilities Poverty Alleviation & Services Disability Care & Services +3 more

Sustainable Slopes Grants

National Ski Areas Association
Private
United States
Unspecified amount
The Sustainable Slopes Grant Program, initiated by the National Ski Areas Association in 2009, supports NSAA member ski areas in their sustainability efforts. With over $890,000 awarded, the program facilitates projects that enhance energy efficiency, protect natural habitats, and promote recycling. This year, applicants can apply for Cash Grants, the Herman K. Dupré Sustainable Snowmaking Grant, or the new Recycling Grant, all aimed at reducing environmental footprints and achieving sustainability goals.
Outdoor Recreation Sustainability Snow Sports

St. Baldrick's Foundation: Infrastructure Awards

St Baldricks Foundation Inc
Private
United States
US $25,000 - US $50,000
The St. Baldrick's Foundation offers Infrastructure Awards to support institutions in enhancing their capacity for childhood cancer clinical trials. These grants are aimed at smaller entities lacking necessary resources, enabling them to hire personnel and acquire vital tools to increase participation. Since 2005, the Foundation has invested over $356 million in childhood cancer research, focusing on collaboration and innovation to find cures. Institutions in the U.S. are eligible, promoting broader access to crucial clinical trials.
Pediatric Cancers

Educational Outreach Program for General Psychiatry Residents Grant Program

American Academy of Child & Adolescent Psychiatry
Private
United States
Up to US $1,200
The AACAP Educational Outreach Program for General Psychiatry Residents offers a unique opportunity for residents to gain insights into child and adolescent psychiatry. Participants will network with mentors and peers, attend the 71st AACAP Annual Meeting from October 14-19, 2024, and receive a stipend of up to $1,200 post-meeting. This program prioritizes first-time applicants, ensuring a valuable experience in a supportive environment while expanding professional connections.
Mental Health & Psychiatric Diseases

Family Medicine Cares USA: New, Free Clinics Program

American Academy of Family Physicians Foundation
Corporate
United States
Up to US $25,000
Family Medicine Cares USA offers grants up to $25,000 to support the establishment of new free clinics. Eligible applicants must either have opened or plan to open within six months of the application deadline and hold the National Association of Free and Charitable Clinics Seal of Excellence. Priority is given to clinics with an AAFP member as medical director and those engaging Family Medicine residents or medical students as volunteers. Applications are accepted annually from March 15 to July 15.
Health Facilities & Clinics

Family Medicine Cares USA Free Health Clinic Grants ( Existing Clinics)

American Academy of Family Physicians Foundation
Corporate
United States
Up to US $10,000
The Family Medicine Cares USA Free Health Clinic Grants support existing clinics in providing care to the uninsured. Grants of up to $10,000 are available if funds permit, prioritizing clinics with AAFP members in leadership roles. The program emphasizes the involvement of Family Medicine residents or medical students as volunteers, aiming to enhance healthcare access in underserved communities.
Health Facilities & Clinics

GSF: Gilead Research Scholars - Oncology

Gilead Sciences Foundation
Private
United States
Up to US $180,000
The Gilead Research Scholars Program in Oncology supports innovative research from emerging investigators worldwide, focusing on scientific understanding and progress in cancer treatment. Launched in 2008, it offers financial support of up to $180,000 over two years to junior faculty who meet eligibility criteria. The program emphasizes diversity and aims to reduce barriers for underrepresented groups in research, fostering a more inclusive landscape in addressing unmet medical needs.
Cancer / Oncology

AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer

American Gastroenterological Association
Association/Society
North America
US $100,000
The AGA-R. Robert & Sally Funderburg Research Award in Gastric Cancer aims to support established investigators in gastric cancer research. This award focuses on enhancing the understanding of gastric cancer pathobiology and developing strategies for prevention, treatment, and cure. Eligibility includes holding an MD or PhD, with specific experience requirements. The American Gastroenterological Association encourages applications, particularly from underrepresented groups in biomedical research, to foster diversity in the field.
Gastrointestinal Cancers

PEN America: Phyllis Naylor Grant for Children’s and Young Adult Novelists

PEN America
Private
United States
US $5,000
The PEN America: Phyllis Naylor Grant for Children’s and Young Adult Novelists awards $5,000 annually to authors of children's or young adult fiction. This grant supports writers at critical stages in their careers, specifically for a novel-in-progress. Candidates must have published works that received positive critical reception but limited sales. Self-published works and collaborative manuscripts are ineligible, ensuring that the grant focuses on authors with established literary merit.
Writing & Literature

Pulitzer Center: U.S. Local News Reporting Grants

Pulitzer Center
Private
United States
Unspecified amount
The Pulitzer Center offers U.S. Local News Reporting Grants aimed at supporting freelance and staff journalists in producing in-depth investigative reporting for local news outlets. This initiative seeks to amplify underreported stories crucial to community engagement, particularly those addressing systemic issues. The grants are available on a rolling basis, encouraging diverse voices in journalism. Applicants must provide a project description, budget estimate, and distribution plan to qualify for funding that covers essential reporting costs.
Journalism

Evergy Community Impact Program

Evergy, Inc.
Private
Buchanan County, Missouri, Cass County, Missouri +11 more
Unspecified amount
Evergy Community Investment focuses on enhancing community vitality and environmental leadership. The program prioritizes funding requests that align with its mission to promote sustainability and economic growth in local areas. By supporting initiatives that foster clean energy, workforce readiness, and community engagement, Evergy aims to create a lasting impact. Eligible applicants must have 501(c)(3) status, while specific ineligible categories include individuals and religious organizations. For detailed inquiries, agencies are encouraged to reach out directly.
Community Development & Revitalization Environmental Justice & Advocacy Environmental Stewardship +2 more

Mighty Therapeutics Grants & Sponsorships

Mighty Therapeutics
Corporate
United States
Unspecified amount
Stealth Biotherapeutics offers grants and sponsorships aimed at enhancing healthcare education for providers and patient communities. These funding opportunities focus on innovative programs that address rare genetic disorders, neurodegenerative conditions, and ophthalmic disorders. To apply, requests must be submitted 60 days prior to the funding start date, ensuring alignment with the therapeutic interests of the organization while providing valuable insights for healthcare professionals.
Medical Education & Professional Training

Mighty Therapeutics: Charitable Contributions

Mighty Therapeutics
Corporate
United States
Unspecified amount
Stealth Biotherapeutics is dedicated to supporting innovative programs that enhance disease awareness and therapeutic management. Their charitable contributions focus on accredited institutions, promoting educational initiatives for health care providers and patient communities. Funding is prioritized for unique and cost-effective projects that align with their therapeutic interests, including rare genetic disorders, neurodegenerative diseases, and ophthalmic conditions. By fostering community awareness, they aim to make a significant impact in the healthcare landscape.
STEM / STEAM Education Environmental Education Human & Social Services +1 more

Get Out the Vote Grant Program

Unitarian Universalist Association
Association/Society
United States
Up to US $1,000

Who We Are

The Unitarian Universalist Funding Program (UUFP) is a denominational grantmaking program of the Unitarian Universalist Association. Inspired by the richness and diversity of our liberal religious tradition, the mission of the UUFP is to promote the influence of Unitarian Universalist principles through grantmaking.

With funds generously provided by the Unitarian Universalist Veatch Program at Shelter Rock, the UUFP awards grants to Unitarian Universalist (UU) and non-UU projects and organizations. Grants are made that:

  • Support the work of social justice.
  • Strengthen Unitarian Universalist institutions.
  • Transform gratitude for being into generosity of living.

Get Out The Vote - 2026

The Fund for UU Social Responsibility has increased funding for grants to UU congregations and organizations working to Get Out The Vote in 2026. Grants of up to $1,000 will be made on a rolling basis until funds are depleted.  

Please note that funds must go to a UU congregation or organization for the work by UUs of the organization. The funds may not be passed through to another organization. Collaboration and partnerships are encouraged.

UU congregations and organizations frequently support the democratic process in an election cycle in a non-partisan* manner by participating in voter registration drives, organizing to stop voter suppression, providing non-partisan educational materials or forums for voters, or by volunteering to help registered voters get to the polls on election day.

Governance & Democracy

Officers’ Research Grants on Reducing Inequality

William T Grant Foundation Inc
Private
United States
US $25,000 - US $50,000
The Officers’ Research Grants on Reducing Inequality support studies aimed at understanding and addressing inequalities affecting youth ages 5-25 in the U.S. This initiative funds descriptive, intervention, and measurement development studies focused on academic, social, behavioral, and economic outcomes. The William T. Grant Foundation encourages research that identifies specific inequalities and explores effective programs or policies to mitigate these disparities while addressing systemic issues such as racism and structural inequality.
Social Justice / Human Rights

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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