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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,709 Results based on applied filters

HAF: Impact Grants (Formerly Innovation Grant)

Hemophilia Alliance Foundation
Private
United States
Up to US $50,000
The Hemophilia Alliance Foundation's Impact Grants aim to support organizations enhancing services for individuals with inherited bleeding disorders. Since its inception in 2009, the foundation has awarded over $6.6 million, enabling innovative projects that expand capacity and collaboration. Eligible applicants include local organizations and federally-funded treatment centers, emphasizing creativity in project proposals. Priority will be given to initiatives that address unserved populations and foster educational advancements in the community.
Diseases & Conditions

Kia Pet Adoption Grant

Petfinder Foundation
Private
United States
Unspecified amount
The Kia Pet Adoption Grant, funded by the Petfinder Foundation as part of the Accelerate the Good program, supports organizations in the US, Canada, and Mexico with free or reduced-fee adoptions for dogs and cats. Grants are awarded monthly based on the number of adoptable pets listed on Petfinder.com until funds are depleted or November 1st. Grantees are required to report adoptions and share stories of pets adopted through this initiative.
Animal Welfare - Domestic Animals & Pets

CTIA Wireless Foundation: Catalyst Grant Program

CTIA Wireless Foundation
Private
American Samoa, Guam +4 more
Up to US $100,000
The CTIA Wireless Foundation's Catalyst Grant Program aims to empower social entrepreneurs leveraging 5G technology to tackle critical challenges in American communities. With over $200,000 in unrestricted grants available, the program supports innovative projects that utilize 5G connectivity for social good. As 5G transforms communication and interaction, the Catalyst Grant seeks visionary leaders who can harness this potential to inspire meaningful change and enhance community engagement.
Emerging Technology Development Artificial Intelligence (AI) Data Science & Digital Information Systems

Digital Wish Donation Program

Mobile Beacon
Corporate
United States
Unspecified amount in in-kind support
The Digital Wish Donation Program, initiated by Mobile Beacon, aims to provide affordable high-speed Internet access to K-12 schools, colleges, and libraries. For just $10 a month, participating institutions can receive donated mobile hotspots and discounted tablets, enabling them to enhance digital literacy and connectivity among underserved students. This initiative not only breaks down barriers to access but also fosters educational equality, ensuring that all learners have the tools they need to succeed in the digital age.
Educational Access & Equity Technology Access & Digital Literacy

Cell Signaling Technology’s Environmental Grants

Cell Signaling Technology
Corporate
United States
US $500 - US $10,000
Cell Signaling Technology’s Environmental Grants support initiatives aimed at ecosystem protection, wildlife research, and environmental education. Priority is given to action-oriented projects with at least 70% of funding allocated to those directly impacting the environment. Applications are accepted annually until May 1st, with a focus on organizations in Massachusetts, particularly the North Shore of Boston. Non-profit status is required, and discriminatory projects will not be funded.
Environmental Conservation Environmental Education Environmental Stewardship +7 more

Frankenthaler Climate Initiative: Scoping Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $25,000
The Frankenthaler Climate Initiative provides funding for energy efficiency projects in visual arts museums, addressing climate change through innovative cultural leadership. Grants up to $25,000 support institutions in evaluating energy mitigation opportunities, enhancing efficiency, and reducing emissions. Eligible applicants include museums and visual arts schools across the U.S. The initiative encourages sustainable practices while assisting organizations in understanding their energy needs and planning for effective interventions within a project timeline of 18 months.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

Frankenthaler Climate Initiative- Implementation Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $100,000
The Frankenthaler Climate Initiative offers implementation grants aimed at enhancing energy efficiency in visual arts museums, addressing climate change through innovative projects. With deadlines extended for those affected by the LA Fires, eligible institutions can apply for funding ranging from $50,000 to $100,000. This initiative supports museums of all sizes, helping them reduce emissions and operational costs while promoting sustainable practices in the arts sector.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

Imagine Learning Foundation: Signature Grant Program

Imagine Learning Foundation
Private
United States
US $25,000 - US $100,000
The Imagine Learning Foundation's Signature Grant Program aims to enhance the well-being of learners by supporting social and emotional learning (SEL) initiatives. By bridging classroom and community efforts, it fosters healthier environments for youth, families, and educators. The program prioritizes funding for organizations addressing critical issues like chronic absenteeism and housing insecurity. In 2024, the foundation will allocate over $400,000 to impactful projects, furthering its mission to cultivate supportive learning experiences both in and out of the classroom.
Youth Services Family Services Teacher Development & Training +4 more

Sports 4 Life Grants

Women’s Sports Foundation
Private
United States
Unspecified amount
The Sports 4 Life Grants, co-founded by the Women’s Sports Foundation and ESPN, aim to promote the health and development of girls in underserved communities. This initiative focuses on increasing participation and retention rates of Black, Hispanic, and Native American girls in sports through funding for coaching, equipment, and facilities. By fostering leadership and self-esteem, the program seeks to empower young girls and provide them with lifelong benefits from sports participation.
Sports & Athletics

RMEF Grant Program- Hunting Heritage

Rocky Mountain Elk Foundation (RMEF)
Private
United States
Unspecified amount

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

Land / Habitat Conservation Sport Shooting Outdoor Recreation +2 more

The Jandy Ammons Foundation Grant

The Jandy Ammons Foundation
Private
United States
Unspecified amount
The Jandy Ammons Foundation, established in 2012, is committed to enhancing local communities through innovative, project-driven initiatives. Focused on 'shovel ready' projects, it supports wildlife conservation, educational efforts, artistic installations, and Christian mission endeavors. By providing resources to IRS-recognized 501(c)(3) charities, the foundation aims to inspire community engagement and sustainable growth. The foundation reflects the collaborative spirit of its founders, Andy and Jan Ammons, who believe in hard work, integrity, and maximizing available resources.
Community Development & Revitalization Land / Habitat Conservation Environmental Conservation +5 more

Kubota Hometown Proud Grant Program

Kubota
Corporate
United States
Up to US $50,000
The Kubota Hometown Proud Grant is a community initiative that will award ten $50,000 grants in 2025, comprising $25,000 in cash and $25,000 in equipment vouchers. Nonprofit organizations are encouraged to apply for projects that enhance their communities, with applications opening April 3 and closing May 9, 2025. Winners will be announced on September 1, 2025, supporting impactful local initiatives across Kubota's operating districts.
Community Development & Revitalization Greening & Beautification Playgrounds +2 more

The Trails Capacity Program

American Trails
Private
Puerto Rico, United States
US $2,000 - US $15,000
The Trails Capacity Program, previously known as the Trail Fund Grant, aims to enhance community capacity for trail maintenance, research, and stewardship training across the nation. The program focuses on supporting non-Forest Service Federal lands, as well as state and local areas, fostering inclusivity and improved user behavior. By collaborating with diverse trail partners, it seeks to ensure effective stewardship and sustainable trail management, ultimately promoting public access and enjoyment of America's natural landscapes.
Trail Creation & Maintenance Environmental Stewardship

Sustainable Disaster-Relief Fund

Vanguard Charitable Endowment Program
Private
United States
Unspecified amount
The Sustainable Disaster-Relief Fund, established by Vanguard Charitable in 2006, aims to support communities affected by natural disasters. By providing funding for rebuilding efforts and necessary infrastructure, this initiative helps ensure that affected areas are better prepared for future disasters. Grants are available to 501(c)(3) organizations in good standing, focusing on charitable purposes like operating expenses and specific projects. The fund plays a critical role in enhancing community resilience and promoting effective disaster recovery.
Disaster Relief / Humanitarian Aid

Truist Foundation: Inspire Awards

Truist Foundation Inc
Private
United States
US $10,000 - US $250,000

Truist Foundation

The Truist Foundation is committed to Truist Financial Corporation's (NYSE: TFC) purpose to inspire and build better lives and communities. Established in 2020, the foundation makes strategic investments in nonprofit organizations to help ensure the communities it serves have more opportunities for a better quality of life. The Truist Foundation's grants and activities focus on building career pathways to economic mobility and strengthening small businesses.

Inspire Awards

This year’s Inspire Awards seeks nonprofits supporting the career navigation and workforce development needs of workers across the United States. The challenge seeks applications that help individuals gain the skills, guidance, and support needed to access quality jobs, advance in their careers, and build long-term stability in an evolving world of work.

2026 Truist Foundation Inspire Awards Challenge Question

How are nonprofits providing innovative direct services, training programs, and career navigation supports for adult workers in the age of AI?

Challenge Dimensions

Nonprofit organizations have long been critical advocates and service providers for workers in the United States. Nonprofits provide workers necessary upskilling opportunities, AI literacy training, career navigation support, and wraparound services in conjunction with career pathways programming. All necessary for the modern workforce. Meeting the moment, Truist Foundation and MIT Solve want to hear the ways in which nonprofits headquartered in the Truist operating footprint are providing innovative career pathway programming in the age of AI. Although solutions don’t need to focus on generative AI specifically, teams should demonstrate how their career pathways programming align with the following dimensions:

  • Training and Upskilling Programs – Providing holistic, accessible programming that equips workers with essential skills, industry-validated credentials, and technical literacy for the modern workplace.
  • AI Readiness and Literacy – Offering high-quality training that helps workers understand generative AI and agentic technologies as augmented intelligence tools, helping to build practical skills like effective prompting, domain expertise application, and ethical use.
  • Additional Wraparound Services and Basic Needs Support – Supporting unemployed and underemployed workers on their journey to economic mobility through comprehensive, integrated resources including childcare, transportation support, mentorship, mental health services, benefits navigation, and more.
  • Career Navigation in the AI Economy – Enabling workers to navigate career choices with clarity and confidence by providing accessible information about how AI is reshaping job roles and industries, facilitating informed decisions about high-quality career trajectories that align with individual circumstances, and connecting workers to industry-validated credentials or trainings.

Here are the grants for this challenge

  • First place: $250,000
  • Second place: $150,000
  • Runners-up: $25,000
  • Audience favorite: $75,000

Business Development Financial Literacy Entrepreneurship +4 more

Richard Beatty Mellon Environmental Stewardship Award

Air & Waste Management Association (A&WMA)
Association/Society
United States
Unspecified amount
The Richard Beatty Mellon Environmental Stewardship Award, established in 1954, honors individuals or organizations for significant contributions to pollution abatement. Eligible candidates demonstrate dedicated efforts in promoting air pollution control and waste management. This prestigious award reflects the legacy of Richard Beatty Mellon, who pioneered research in air quality and environmental protection. The award is open to both members and nonmembers of the Air & Waste Management Association.
Environmental Contamination & Pollution Environmental Stewardship Waste Management

KidsGardening: Youth Garden Grant

KidsGardening
Private
American Samoa, Guam +4 more
US $500
The KidsGardening Youth Garden Grant supports organizations in the U.S. or U.S. Territories that aim to enhance youth gardening programs. With a focus on underserved communities, the grant provides resources to develop or improve garden projects for youth aged 0-18. This initiative not only promotes educational opportunities but also fosters community engagement through gardening. Recipients receive a variety of supplies, including seeds and gardening tools, to help cultivate sustainable gardening practices.
Horticulture & Gardening

TKoster’s Charitable Innovated Health Care Award

American College Health Foundation
Corporate
United States
Up to US $2,500
The TKoster’s Charitable Innovated Health Care Award, established by Teresa Koster, aims to enhance students' access to quality health care. With a funding amount of $3,500, this award supports innovative practices in student health centers. It addresses critical areas such as understanding health care needs, improving service delivery, and leveraging technology. Eligible applicants include members of the American College Health Association, encouraged to demonstrate partnerships and financial support in their proposals.
Health Care Access & Delivery School Health

Wilbur Awards

Religion Communicators Council
Private
United States
Unspecified amount
The Wilbur Awards, presented annually since 1949 by the Religion Communicators Council, celebrate excellence in communicating religious values and themes in secular media. Open to individuals and organizations, entries must have been published or broadcast in 2024. Categories include audio, audio-visual, images, and written works, allowing for both English and non-English submissions. The awards emphasize professionalism and respect in highlighting uplifting religious narratives within diverse media platforms.
Religion & Spirituality Religious / Theological Education Interfaith Cooperation / Religious Freedom

ASCFG Research Foundation Grant

Association Of Specialty Cut Flower Growers Inc
Association/Society
United States
US $30,000
The ASCFG Research Foundation Grant, offered by the Association of Specialty Cut Flower Growers, aims to support innovative research projects that benefit specialty cut flower growers. The program, open to academia, government, and industry researchers, will distribute up to $30,000 in grants in 2026. Proposed research should last one year or less and can include multi-year projects. Recipients are expected to present their findings at ASCFG meetings, fostering collaboration and advancement in the cut flower industry.
Horticulture & Gardening Plant Science

The Flowers Fund Grant

Human Rights Educators USA
Private
United States
Up to US $1,000
The Flowers Fund Grant, established by HRE USA in 2017 to honor founding member Nancy Flowers, offers annual small grants of up to $1000. It aims to support innovation and mentorship in human rights education in the U.S., encouraging new ideas and outreach methods. Applications are open to HRE USA members for projects relevant to human rights education, with a focus on research, conferences, and leadership. Grants are intended for completion within the academic year.
Social Justice / Human Rights

Edward O’Brien Award

Center for Transformative Action (CTA)
Private
United States
Unspecified amount
The Edward O’Brien Human Rights Education Awards, established by Human Rights Educators USA (HRE USA) in memory of Ed O’Brien, honor individuals and organizations making significant contributions to human rights education in the U.S. Nominations for the 2024 awards are open to both individuals and organizations. Any member of HRE USA or its affiliates can nominate, while non-members are encouraged to join before submitting nominations. These awards aim to recognize and promote impactful human rights education.
Social Justice / Human Rights

The Chisholm Foundation Grants

Chisholm Foundation
Private
United States
Unspecified amount
The Chisholm Foundation offers grants to support arts, education, and religion projects across the United States. Applications for May and November grants should be submitted by March 1st and September 1st, respectively. The Foundation evaluates each application individually and encourages innovative projects that can attract additional funding. Grants may be awarded as lump sums or in installments, and applicants are advised to seek matching gifts to enhance their proposals.
Art & Culture Education Religion & Spirituality

Barnes-Jewish Hospital Community Support Grants

Bjc Health System
Private
St. Louis County, Missouri
Approximately US $33,000
The Barnes-Jewish Hospital Community Support Grants program provides funding to not-for-profit organizations to enhance health care in the St. Louis area. Grants can support new projects or expand existing ones, focusing on reducing health disparities, fostering strong health networks, and promoting wellness. Applications are accepted year-round and reviewed quarterly, with an average grant amount of $33,000. Note that certain requests, such as for ordinary operating expenses or capital projects, are not eligible.
Health & Medicine Community Health Education Preventative Healthcare +3 more

Takeda: Corporate Giving

Takeda
Corporate
United States
Unspecified amount
Takeda's Corporate Giving program focuses on enhancing community well-being in the U.S. by supporting initiatives in two key areas: Food is Health and Building STEM Foundations. Through employee engagement and partnerships, Takeda aims to provide access to nutritious food and foster STEM education, addressing social disparities and empowering future innovators. This commitment reflects Takeda's mission of better health and a brighter future for all.
Health & Medicine Environment Education +7 more

ASSET Grant Program

United Way Of Greater St Louis Inc
Private
Calhoun County, Illinois, Clinton County, Illinois +14 more
Up to US $25,000
The ASSET Grant Program, developed in partnership with United Way of Greater St. Louis, provides vital financial education and asset building opportunities for low-income families with children. It aims to enhance financial literacy through goal setting, personalized counseling, and comprehensive coaching, including a savings match of $300. Supported by generous donations from Stifel Bank, U.S. Bank, and Wells Fargo, the program empowers families to achieve their financial goals and improve their overall economic stability.
Financial Literacy Family Services Economic Services & Development

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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