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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,673 Results based on applied filters

Individual Provider Grants

Making a Difference Foundation
Private
United States
Up to US $2,000
Individual Provider Grants empower medical providers to contribute to communities through medical mission trips. These grants fund nonprofit organizations to assist with program costs. Applications are accepted year-round, but should ideally be submitted 30-60 days prior to the mission for timely processing. The Making a Difference Foundation reviews all applications monthly; however, meeting eligibility does not ensure funding at the requested amount.
Health & Medicine Medical Education & Professional Training

End of Life Care or Preventing Elder Neglect Grant

The Sephardic Foundation on Aging
Private
United States
Unspecified amount
The Sephardic Home For The Aged Foundation offers grants focused on end-of-life care and preventing elder neglect. They encourage nonprofits with a 501(c)3 status, operational for at least two years, to apply for funding. The foundation prioritizes innovative programs that enhance the quality of life for older adults through education, advocacy, and community outreach. Interested organizations should submit a Letter of Inquiry before applying for the grant.
Senior Services Hospice / End of Life Care

Dementia Care and Brain Degenerative Diseases Grant

The Sephardic Foundation on Aging
Private
United States
Unspecified amount
The Dementia Care and Brain Degenerative Diseases Grant, offered by the Sephardic Home For The Aged Foundation, aims to support innovative projects enhancing care and quality of life for older adults affected by dementia. Eligible organizations must be 501(c)3 nonprofits in operation for at least two years. The Foundation prioritizes proposals focusing on dementia care, promoting collaboration and resource access for aging individuals. Interested applicants should submit a Letter of Inquiry through the online application system.
Senior Services Dementia & Alzheimer’s Disease

Combating Social Isolation of Older Adults Grant

The Sephardic Foundation on Aging
Private
United States
Unspecified amount
The Combating Social Isolation of Older Adults Grant, provided by the Sephardic Home for the Aged Foundation, aims to combat elder abuse and neglect exacerbated by social isolation. This initiative recognizes that isolation can lead to severe mental and physical health issues among older adults. It promotes trauma-informed care and mental health services to help these individuals reconnect socially. Additionally, the Foundation supports intergenerational programming as a vital strategy to foster community connections and reduce isolation among seniors.
Senior Services Social Isolation

NSCDA National American Indian Medical Scholarship Award Program

National Society of the Colonial Dames of America
Private
United States
More than US $1,500
The NSCDA National American Indian Medical Scholarship Award Program provides scholarships to students of American Indian descent, originally focusing on women in nursing. Launched in 1928, the program now supports males and various health-related fields. Eligible applicants must demonstrate tribal enrollment or ancestry, maintain academic standing, and have a commitment to serving their communities. The scholarship awards $1,500 each semester for tuition and academic expenses, helping students fulfill their educational and career goals.
Academic Scholarship Programs Indigenous Sovereignty & Rights Indigenous Services

Phased Large Awards for Comparative Effectiveness Research PCORI Funding Announcement -- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $22,000,000
The Patient-Centered Outcomes Research Institute (PCORI) will announce the Phased Large Awards for Comparative Effectiveness Research on December 2, 2025. This funding aims to support high-quality, patient-centered comparative clinical effectiveness research projects. The initiative encourages applicants to engage with patients and stakeholders to address critical healthcare dilemmas and improve decision-making. Projects should compare established clinical alternatives with evidence of efficacy, targeting vital health issues across diverse populations.
Addiction & Substance Use Disorders Mental Health & Psychiatric Diseases Cardiovascular Diseases & Systems +2 more

King-Rockwell Scholarship Renewal

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
US $1,000
The King-Rockwell Scholarship Renewal aims to address the diverse needs of the community through innovative funding solutions. This private foundation is dedicated to holistic support in education, arts, infrastructure, and wellness. Eligible applicants are those who have previously received the King-Rockwell Scholarship, ensuring continuity in nurturing talent and community engagement. This initiative not only provides financial assistance but also fosters awareness and collaboration for a sustainable future.
Academic Scholarship Programs

Turner Family Scholarship Fund

Community Foundation of Middle Tennessee
Private
United States
US $1,500 - US $2,500
The Turner Family Scholarship Fund, established by Cal Turner Sr. in 1999, supports Dollar General employees and their children in their pursuit of education. This initiative reflects the Turner family's commitment to personal development and community support, fostering a culture of growth and opportunity. With over 30 years of impactful philanthropy, the Community Foundation of Middle Tennessee champions this scholarship to enhance educational access, empowering individuals to thrive in their chosen fields.
Academic Scholarship Programs Education - Higher Education Adult Education +1 more

Toward An Inclusive Architecture Scholarship Fund

Community Foundation of Middle Tennessee
Private
United States
Unspecified amount
The Toward An Inclusive Architecture Scholarship Fund, managed by the Community Foundation of Middle Tennessee, aims to empower Tennesseans of color by providing financial support for architectural education. This initiative not only covers educational expenses at accredited architecture schools but also enhances professional growth through internship placements at partner firms. By fostering diversity in architecture, the scholarship seeks to create a more inclusive and thriving community in Tennessee.
Education - Higher Education Academic Scholarship Programs Minority Services +1 more

The Sponsors Scholarship Fund

Community Foundation of Middle Tennessee
Private
Allen County, Kentucky, Bedford County, Tennessee +40 more
Unspecified amount
The Sponsors Scholarship Fund, established by the Community Foundation of Middle Tennessee, has awarded over $2.5 million in scholarships over 20 years to support financially disadvantaged students. This initiative continues the legacy of George Langstaff, who aimed to enhance educational opportunities and economic prospects for youth in Middle Tennessee and Allen County, Kentucky. By fostering collective philanthropy, the fund empowers young individuals to pursue higher education and contribute positively to their communities.
Academic Scholarship Programs Education - High School

Executive Nurse Leadership Scholarship- Wharton Nursing Leaders Program Scholarship

Oncology Nursing Society
Private
United States
Up to US $8,000
The Wharton Nursing Leaders Program Scholarship, offered by the Oncology Nursing Foundation, supports nurse-managers aspiring to become chief nursing officers. This program, taking place from December 15-19, 2025, in Philadelphia, focuses on enhancing leadership skills through interactive sessions. Applicants must first be accepted into the program and meet specific eligibility criteria, ensuring that the scholarship aids those committed to advancing their careers in oncology nursing.
Nursing

The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis

Spondylitis Association Of America
Private
Canada, United States
US $30,000
The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis, offered by the Spondylitis Association of America, aims to support MDs and PhDs at the Instructor or Assistant Professor level in the US and Canada. This annual $30,000 research grant promotes innovative research in ankylosing spondylitis and enhances patient care by encouraging emerging researchers to contribute to this important field.
Skeletal Diseases Arthritis

Hayden Family Scholarship

Community Foundation of Northeast Alabama
Private
United States
Unspecified amount
The Hayden Family Scholarship, established by Ms. Jerry Hayden in memory of her father, supports students pursuing an associate's or bachelor's degree, or workforce training in Alabama. It is open to part-time and full-time students at accredited U.S. institutions and can be renewed annually for up to four years, contingent on maintaining eligibility. Funds can be utilized for tuition, housing, and educational supplies, emphasizing the importance of exploring additional financial resources.
Education - Higher Education Workforce Preparation & Job Readiness Academic Scholarship Programs

Improving Health Decision Making With Comparative Clinical Effectiveness Research: Retrospective Observational Studies Leveraging Existing Data Sources PCORI Funding- Cycle 1 2026

Patient-Centered Outcomes Research Institute
Association/Society
United States
Up to US $2,000,000
This funding opportunity from the Patient-Centered Outcomes Research Institute aims to enhance health decision-making through comparative clinical effectiveness research, focusing on critical areas such as cancer, maternal health, and mental health. The initiative encourages robust observational studies that utilize existing data to derive patient-centered insights. Applications must address specific themes approved by PCORI and demonstrate potential benefits to the U.S. healthcare system, thus ensuring relevance and stakeholder engagement in research efforts.
Cancer / Oncology Maternal And Perinatal Health Endocrine & Metabolic Diseases +2 more

Quad Cities Mexican American Organization Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $1,000
The Quad Cities Mexican American Organization Scholarship, administered by the Quad Cities Community Foundation, offers up to $1,000 to students of Hispanic descent pursuing post-secondary education. Applicants must maintain a GPA of at least 2.0 and can apply for renewal. This scholarship aims to support educational advancement in the Quad Cities region, reflecting a commitment to fostering academic success among underrepresented communities.
Academic Scholarship Programs Hispanic and Latino Services

Dr. Doris R. Corbett -Johnson Leaders for Our Future Award

Society Of Health And Physical Educators
Private
United States
Unspecified amount
The Dr. Doris R. Corbett-Johnson Leaders for Our Future Award, presented by SHAPE America, honors young professionals under 36 who exhibit exceptional promise in scholarship, teaching, and leadership. This prestigious award is available in two categories: college/university and non-college/university, with a maximum of two recipients per category each year. By recognizing emerging leaders, SHAPE America aims to inspire a new generation dedicated to advancing health and physical education.
Education Health & Medicine Sports & Athletics

Paul and Beverly Eckert Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $16,000
The Paul and Beverly Eckert Scholarship, offered by the Quad Cities Community Foundation, provides financial support of up to $4,000 annually to graduating seniors from select Davenport high schools. This scholarship is renewable for up to four years, assisting students pursuing their education at accredited colleges, universities, or trade schools. The foundation is dedicated to enhancing educational opportunities and fostering community growth through generous donor contributions.
Career / College Preparation Academic Scholarship Programs

Paul and Barbara Yamber Memorial STEM Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $40,000
The Paul and Barbara Yamber Memorial STEM Scholarship, administered by the Quad Cities Community Foundation, provides need-based financial support for students pursuing STEM fields. Annually, up to $10,000 is awarded, renewable for up to four years. Applicants must demonstrate financial need and a commitment to STEM education, ensuring that this scholarship significantly impacts their ability to attend college. Preference is given to undergraduates, making this a vital resource for aspiring STEM professionals.
Academic Scholarship Programs STEM / STEAM Education

C.V Glassco Memorial Scholarship Fund

Community Foundation of Northeast Alabama
Private
United States
Unspecified amount
The C.V. Glassco Memorial Scholarship Fund honors Mr. Clarence Verbal Glassco, a dedicated community volunteer and veteran. This scholarship supports full-time students pursuing higher education or approved workforce training in Alabama. Funded by the Community Foundation of Northeast Alabama, it covers tuition, housing, and books based on available assets. Applicants are encouraged to seek additional financial resources. This initiative preserves Mr. Glassco's legacy of service and commitment to education.
Civic Leadership Development Academic Scholarship Programs Education - Higher Education +1 more

Michigan Professional Insurance Agents Scholarship (MIPIA)

Four County Community Foundation
Private
United States
US $1,000 - US $2,000
The Michigan Professional Insurance Agents Scholarship (MIPIA) is offered by the Four County Community Foundation to seniors and recent graduates in Michigan planning to major in Insurance/Risk Management. This scholarship provides up to four awards and aims to foster education in the insurance field. Award recipients will be honored at the Foundation Scholarship Celebration in May, ensuring recognition of their achievements and contributions to the community.
Education - Higher Education Academic Scholarship Programs Business Education +2 more

Morency Family Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $8,000
The Morency Family Scholarship supports young adults from foster care backgrounds in pursuing higher education or vocational training. This scholarship aims to assist those who may face financial barriers after high school graduation. With a focus on applicants from specific counties in Illinois and Iowa, the scholarship provides up to $2,000 annually and is renewable until graduation or age 25, contingent on maintaining a minimum GPA of 2.0.
Career / College Preparation Academic Scholarship Programs

Mike Condon Memorial Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $3,000
The Mike Condon Memorial Scholarship offers financial support to students interested in construction, with awards of up to $1,500 per year. Applicants must have a minimum 2.25 GPA and reside in Clinton, Scott, or Muscatine counties. The scholarship allows for reapplication up to four times, emphasizing trade experience. Preference is given to those with relevant educational backgrounds or participation in construction-related activities, ensuring a focus on developing skills in this vital industry.
Education - Higher Education Vocational & Trade Education Academic Scholarship Programs

Russell W. Ligon Memorial Engineering Scholarship

Four County Community Foundation
Private
United States
US $1,000
The Russell W. Ligon Memorial Engineering Scholarship, offered by the Four County Community Foundation, supports high school seniors and recent graduates from seven school districts pursuing degrees in engineering or computer science. Eligible students can receive up to four awards of $1000 each, contingent upon a GPA of 3.00 or higher, a letter of recommendation, and an essay response. Awardees will be recognized at the Foundation Scholarship Celebration and local high school awards events.
Engineering Computer Science & Engineering Academic Scholarship Programs +1 more

Loren and Tammy Bockwoldt Family Scholarship

Quad Cities Community Foundation
Private
United States
Up to US $8,000
The Loren and Tammy Bockwoldt Family Scholarship, administered by the Quad Cities Community Foundation, awards up to $2,000 annually to three qualified students, totaling no more than $6,000. Applicants must be high school seniors from Durant or Wilton, Iowa, with a minimum GPA of 2.5 and demonstrated financial need. The scholarship is renewable for up to four years, supporting students aiming for full-time enrollment in accredited post-secondary institutions.
Career / College Preparation Academic Scholarship Programs

Koerner Family Foundation Scholarship

Four County Community Foundation
Private
United States
Up to US $7,000
The Koerner Family Foundation Scholarship, offered by the Four County Community Foundation, supports high school seniors and recent graduates from Almont, Dryden, and Romeo High Schools. Eligible students must plan to major in business, engineering, IT, medical health fields, natural sciences, or vocational training, with a minimum GPA of 2.50. Award recipients will be honored at a Scholarship Celebration in May and at their respective high school awards events.
Engineering Natural Resources Veterinary Science & Services +4 more

Fund for Women of the Southern Tier Education Grant

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
US $500
The Fund for Women of the Southern Tier Education Grant aims to eliminate barriers to education for women in the community. This grant supports various educational expenses, including college textbooks, technical supplies, and past due tuition bills. By addressing the holistic needs of the community, the grant provides essential resources to empower women in their educational pursuits. Funded by the Community Foundation of Elmira-Corning and the Finger Lakes, Inc., this initiative fosters educational growth and opportunity.
Academic Scholarship Programs Student Retention & Drop-Out Prevention

Ethel Strickarz Memorial Scholarship

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
United States
Unspecified amount
The Ethel Strickarz Memorial Scholarship aims to address community needs through educational support in special education and related fields. Funded by the Community Foundation of Elmira-Corning and the Finger Lakes, it encourages students pursuing careers in human services, nursing, psychology, speech pathology, or therapy. This scholarship reflects a commitment to holistic community development by fostering future professionals dedicated to improving lives and addressing urgent societal challenges.
Psychology Nursing Physical Therapy +3 more

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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