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Best Massachusetts Grants for Nonprofits

Find nonprofit grants in Massachusetts, including opportunities in Boston, Worcester, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$3.29B

Total funding

$5K

Median grant

10,000+ grants
$3.29B total
$5K median

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9,801 Results based on applied filters

Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed) (357002)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
This funding opportunity invites applications for R01 grants focused on molecular imaging methods to explore cancer inflammation in vivo. It aims to enhance understanding of dynamic interactions between inflammation and cancer through innovative imaging techniques. The initiative encourages collaborations between cancer researchers and imaging scientists to leverage molecular imaging for identifying cellular physiology changes in response to treatment. Deadline dates for applications range from February 2025 to October 2027, emphasizing timely submission for prospective researchers.
Cancer / Oncology Biomedical Imaging

Journey For Good Grant

Journey for Good Foundation, Inc.
Private
North America
Unspecified amount
The Journey For Good Grant aims to combat poverty by supporting charitable organizations in North America focused on food security, housing, education, and workforce development. The grant prioritizes initiatives that provide nutritional wellness, combat homelessness, and support veterans and their families. By fostering partnerships among nonprofits, government, and business, the foundation addresses the interconnected challenges faced by economically vulnerable individuals, creating sustainable solutions for community empowerment.
Education Food Access & Hunger Workforce Preparation & Job Readiness +2 more

NewSchools: Learning Differences Grant Program

NewSchools Venture Fund
Private
United States
US $150,000 - US $250,000
The NewSchools Learning Differences Grant Program aims to enhance educational opportunities for students who learn differently, particularly those affected by poverty and racism. The program invests in innovative solutions and models that support personalized education for these students, ensuring they have access to quality instruction and belonging within school communities. With a focus on equity, it seeks ideas that align with its core investment areas and addresses the needs of marginalized learners.
Education - K through 12 Teacher Development & Training Career / College Preparation +1 more

Artemas W. Stearns Trust Grant

Artemas W Stearns Trust c/o Marsha E Rich ESQ
Private
Essex County, Massachusetts
Unspecified amount
The Artemas W. Stearns Trust Grant supports projects that benefit the indigent aged and deserving poor in Lawrence, Massachusetts. Organizations must demonstrate a direct impact on these communities to qualify for funding. With a focus on improving the lives of vulnerable populations, this trust aims to foster meaningful contributions to the well-being of its recipients. Applications are encouraged from those aligned with the mission of aiding the less fortunate in the city.
Senior Services Poverty Alleviation & Services

DGF Bridge Grants

Dramatists Guild Foundation
Private
United States
US $500
The DGF Bridge Grants provide essential financial support of $500 to professional dramatists facing hardships. This one-time award helps cover non-emergency daily expenses such as housing, utilities, and healthcare. Eligible applicants must be U.S.-based dramatists with limited financial resources and have not previously received a DGF Bridge Grant. By nurturing today's creators, DGF ensures the continuation of impactful storytelling in the theater community.
Theater Basic Human Needs Mental Health & Psychiatric Diseases +1 more

Cape & Coast Bank Foundation Grant

Cooperative Bank Of Cape Cod Charitable Foundation Trust
Private
Barnstable County, Massachusetts
More than US $2,500
The Cape & Coast Bank Foundation Grant focuses on five key pillars that address critical community needs, including building community connections, enhancing financial and economic vitality, promoting health and wellbeing, providing housing solutions, and supporting families. Grants start at $2,500 and target 501(c)(3) non-profit organizations operating for at least three years in Barnstable County. The foundation seeks to fund impactful programs that make a tangible difference in the lives of Cape Cod residents, ensuring funds remain local.
Education Youth Services Family Services +22 more

Artemas Stearns Trust Grant

Artemas W Stearns Trust c/o Marsha E Rich ESQ
Private
Essex County, Massachusetts
Unspecified amount
The Artemas Stearns Trust Grant supports projects aimed at assisting the indigent elderly and deserving poor in Lawrence, Massachusetts. Organizations applying must demonstrate a direct benefit to these populations. However, the trust does not fund individuals, endowments, capital campaigns, or construction projects. This targeted approach ensures that the funds contribute effectively to the welfare of vulnerable community members.
Aging / Gerontology Poverty Alleviation & Services Indigenous Services

Roy & Gloria Dinsdale Foundation Grant

Roy And Gloria Dinsdale Foundation
Private
United States
More than US $10,000
The Roy and Gloria Dinsdale Foundation, established in 2022, is dedicated to enhancing lives in rural Nebraska, Wyoming, and Colorado through grants exceeding $10,000. It supports nonprofits and government entities focused on food, shelter, healthcare, education, and the arts. The foundation prioritizes local initiatives that enrich communities and improve access to essential services, while maintaining a commitment to assisting veterans, first responders, and individuals with disabilities.
Art & Culture Education Arts / Culture Access & Participation +9 more

NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed) (357072)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Dentist Scientist Career Transition Award (K22) supports dentists transitioning from NIH postdoctoral roles to tenure-track faculty positions. It provides two years of mentored research training in the NIH Intramural Research Program, followed by three years of independent research funding at an extramural institution. Key deadlines for grant applications include February 12, 2025, and subsequent dates in June and October 2025, with additional deadlines for renewal and AIDS-related applications.
Dental Health Medical Education & Professional Training

PLTW Computer Science - New Program

Project Lead The Way Inc
Private
American Samoa, District of Columbia +5 more
US $14,000
Project Lead The Way Inc is offering a grant of $14,000 to schools looking to implement the PLTW Computer Science program for the first time. Schools must commit to offering PLTW Computer Science courses over the next three years, ensuring that at least one course is available in the first year. This funding will support program implementation costs, with awards distributed directly to PLTW accounts for eligible schools.
Computer Science & Engineering

Vilcek Foundation Grants

The Vilcek Foundation Inc
Private
American Samoa, Guam +4 more
US $5,000 - US $20,000
The 2025 Vilcek Foundation Grants aim to support nonprofit organizations that celebrate immigrant contributions to the arts and sciences. The foundation invites applications from organizations operating under U.S. IRS Section 501(c)(3) that promote diversity and inclusivity. Grants will be prioritized for new partners and those in states without prior funding. This initiative underscores the foundation's commitment to fostering appreciation for immigrant communities and their impact on society.
Immigrant Services Art & Culture Education - Higher Education +1 more

Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (357112)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Focused Technology Research and Development (R01) grant supports innovative projects aimed at developing technologies to enhance biomedical research. This funding opportunity emphasizes the creation of laboratory instruments, algorithms, and biological systems that can significantly improve research capabilities. Key deadlines for applications are set for February, June, and October of 2025 through 2027, ensuring ample time for proposal submissions. The initiative is funded by the National Institutes of Health (NIH), part of the US Department of Health and Human Services.
Biotechnology Biomedical Imaging Medical Technology, Devices, and Equipment +1 more

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health

Impact100 Global Veterans Awards

Impact100 Global Veterans
Private
American Samoa, Guam +4 more
Up to US $100,000
The Impact100 Global Veterans Awards empower women to make a significant difference by awarding grants up to $100,000 to nonprofits that serve veterans. Focus areas include art and culture, education, health and wellness, environment, and family initiatives, promoting the well-being and support of veterans across the United States. Eligible organizations must meet specific criteria, including tax-exempt status, and are encouraged to submit proposals that utilize funds effectively within two years.
Art & Culture Military & Veterans Services Educational Access & Equity +17 more

Better Utilizing Investments to Leverage Development (BUILD) Grant Program

US Department of Transportation (USDOT)
Federal Government
American Samoa, Guam +4 more
Up to US $25,000,000
The BUILD Grant Program, managed by the USDOT, focuses on enhancing surface transportation infrastructure with substantial local impact. It supports a variety of project sponsors, including state and local governments, in pursuing complex multi-modal initiatives that are often challenging to fund through traditional grants. Established under the American Recovery and Reinvestment Act of 2009, this program reflects a commitment to sustainable and equitable infrastructure development.
Public Infrastructure Public Transportation & Mass Transit Systems

Weatherization Assistance Program

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Weatherization Assistance Program (WAP) by the U.S. Department of Energy provides essential services to improve energy efficiency in homes, particularly for low-income households. Eligible participants include those below 200% of the poverty level, renters, and homeowners. The application process involves determining eligibility, identifying local providers, and submitting necessary documentation. By helping families save on energy costs and enhancing comfort, WAP plays a crucial role in supporting vulnerable communities.
Homeownership Equitable & Affordable Housing Energy Efficiency & Conservation

Disaster Relief and Resilience Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Disaster Relief and Resilience Scholarship supports residents of western North Carolina whose education funding has been affected by Hurricane Helene. Offered by the North Carolina Community Foundation, this scholarship is available for undergraduate and graduate students attending two- or four-year colleges. The minimum award is $1,000, aimed at helping students overcome financial hardships caused by the disaster and continue their educational pursuits.
Education - Higher Education Disaster Relief / Humanitarian Aid

Bass Pro Shops Large Grant

Friends of Reservoirs
Private
United States
Up to US $100,000
The Friends of Reservoirs: Large Grant supports fish habitat enhancement projects in manmade reservoirs, promoting conservation and partnerships. With approximately $250,000 in Federal funding and $500,000 from Bass Pro Shops, grants up to $75,000 are available. Projects must match funding and can be multi-year, with specific caps on subsequent funding. This initiative aims to address habitat impairments and enrich community quality of life through improved fishing opportunities.
Habitat & Ecosystem Restoration Fisheries Freshwater Conservation +1 more

Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) (358375)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Intervention Research to Improve Native American Health initiative aims to enhance health outcomes in Native American communities through innovative research. This program supports studies focused on health promotion, disease prevention, and culturally informed treatment strategies. Key deadlines for grant applications are October 21, 2025, and January 7, 2026. By addressing health disparities and leveraging community strengths, the initiative fosters sustainable interventions tailored to specific cultural contexts.
Indigenous Health Systems Native American Services Health Disparities & Social Determinants of Health

Intervention Research to Improve Native American Health (R34 Clinical Trial Optional) (358373)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $450,000
The Intervention Research to Improve Native American Health (R34) aims to support research that enhances health interventions for Native American populations. This includes studying the efficacy of health promotion and disease prevention strategies, culturally informed treatments, and addressing existing health disparities. The initiative encourages community-based solutions that are sustainable and adaptable to various Native American tribes. Key deadlines for grant applications are set for October 2025 and 2026, with additional dates for AIDS-related proposals.
Health Disparities & Social Determinants of Health Indigenous Health Systems Native American Services

Aim High Grant Program: One-Year Grants

New York Life Foundation
Corporate
United States
US $20,000
The Aim High Grant Program offers one-year grants of $20,000 to support out-of-school time programs for middle school youth. Funded by the New York Life Foundation, this initiative aims to enhance students' transition to high school by providing essential skills and guidance. Programs must demonstrate effective engagement strategies and serve low-income communities. This grant represents a vital investment in the future of young people, helping them develop academically, socially, and emotionally.
After School / Summer Educational Programs Education - Middle School

Public Humanities Projects (358390)

National Endowment for the Humanities (NEH)
Federal Government
United States
US $75,000 - US $500,000
The Public Humanities Projects program, funded by the National Endowment for the Humanities, promotes innovative projects that connect humanities scholarship with the general public through diverse programming formats. It aims to explore significant themes in history, literature, ethics, and art history, fostering a deeper understanding and appreciation of the humanities in society. This initiative seeks to create engaging experiences that resonate with various audiences.
Humanities & Social Science Writing & Literature Art History

The Alice M. Ditson Fund: Recording Projects

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund supports recording projects that aim to document and promote the music of younger, lesser-known American composers. The fund prioritizes living composers of classical concert music, especially those in the early stages of their careers, while also recognizing established composers who deserve greater visibility. Eligible applicants include organizations with a fiscal sponsor or non-profit status, and projects must involve significant contemporary American music.
Classical Music

The Alice M. Ditson Fund: Organizational Support - Spring Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.
Classical Music Opera Dance

The Alice M. Ditson Fund: Organizational Support - Fall Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund offers organizational support for summer festivals and conferences focused on contemporary American classical music. This funding opportunity encourages the appreciation of works by younger, relatively unknown American composers. Eligible applicants include performing organizations and institutions that promote artistic excellence. The Fund emphasizes supporting living composers at various career stages, ensuring a broader recognition of their contributions to classical concert music. It is crucial for applicants to align their projects with the Fund's mission of enhancing public knowledge and appreciation.
Music Festivals Classical Music

Janet's Fund Grant

The Berkshire Taconic Community Foundation
Private
Berkshire County, Massachusetts
Up to US $5,000
Janet's Fund Grant, established in memory of Janet Thieriot, aims to enhance the educational experience of students in the Southern Berkshire Regional School District. The fund provides financial resources for creative initiatives that support both individual students and broader school programs, particularly those addressing the needs of diverse learners. Grants typically range from $250 to $5,000, encouraging applicants to seek matching funds and focus on direct project costs. This initiative fosters innovation and excellence within the community.
Academic Success & Enrichment Rural Development

Arthur C. Cope Postdoctoral Fellowship in Organic Chemistry

American Chemical Society
Association/Society
American Samoa, Guam +4 more
Up to US $170,000
The Arthur C. Cope Postdoctoral Fellowship, awarded by the American Chemical Society, recognizes outstanding achievements in organic chemistry. This two-year fellowship provides $85,000 annually to early-career researchers, promoting innovative research in sustainable organic chemistry. Candidates, nominated by their mentors, must demonstrate excellence and a commitment to inclusivity in research. The fellowship encourages participation in ACS activities, fostering career development and collaboration within the scientific community.
Chemistry

Massachusetts Grants for Nonprofits Highlights

Massachusetts grants for nonprofits provide funding to support innovation in education, technology, and public health. The following grants help organizations tackle challenges, promote sustainability, and enhance quality of life for communities across the state.


Search Instrumentl's Massachusetts Grants Database


Find 247 funding opportunities for nonprofits in Massachusetts, with $68.5M available. Instrumentl provides nonprofits with deadline management tools, customized grant searches, and strategic insights to support impactful projects across the state.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Massachusetts Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Massachusetts grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

96 Massachusetts grants for nonprofits over $25K in average grant size

77 Massachusetts grants for nonprofits over $50K in average grant size

59 Massachusetts grants for nonprofits supporting general operating expenses

200+ Massachusetts grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Human & Social Services

3,000+ Grants on Instrumentl focused on Education

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Massachusetts grants for Nonprofits?

Most grants are due in the first quarter.

Q1
31.6%
Q2
25.7%
Q3
18.6%
Q4
24.1%

Typical Funding Amounts

What's the typical grant amount funded for Massachusetts Grants for Nonprofits?

Grants are most commonly $27,500.

$250 $250 Min.
$27,500 $27.5 K Median
$410,471 $410.5 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

According to data from the IRS, funding for nonprofits in Massachusetts increased drastically from 2021 to 2022. The 20.67% increase saw funding amounts jump from $11.7B in 2021 to $14.1B in 2022. The most common grant focus areas in Massachusetts during this time were professional societies, associations, research institutes and/or public policy analysis, and alliance/advocacy organizations. Suffolk County, Middlesex County, and Norfolk County received the most funding across the state.

Instrumentl is the only complete grant solution that allows nonprofits to discover opportunities, cultivate relationships, apply for grants, streamline the application process, and report on grant management.

Learn more about how to find grants for your nonprofit.

When applying for funding, nonprofits in Massachusetts should be aware that of the available grants, 31.6% are due in Q1, while 25.7% are due in Q2. Fewer application deadlines fall in Q4 and Q3 as 24.1% and 18.6%, respectively, are due during these periods.

There are more than 200+ grants with a total of $68,548,642 in funding available to Massachusetts nonprofits. These grants, which have a median funding amount of $27,500, support organizations that address everyday challenges, promote sustainability, and enhance the quality of life for communities across the state.

The majority of grants available to Massachusetts nonprofits are funded by private organizations. State and local governments and corporations also provide funding for grants.

  • Private Organizations: Private organizations provide 124 grant opportunities that support causes such as environmental conservation, sustainability, and health and medicine.
  • State and Local Government: State and local government agencies support 77 grants and provide funding for agriculture, museums and cultural institutions, and homeland security.
  • Corporations: Corporations fund 22 grants for Massachusetts nonprofits that support homelessness services, entrepreneurship, affordable housing, and more.
    • Be sure to review all grant application requirements and deadlines to improve your chances of securing funding.

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