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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,702 Results based on applied filters

Dermatology Foundation: Research Grant

Dermatology Foundation
Private
United States
US $25,000
The Dermatology Foundation offers a Research Grant of $25,000 annually to support innovative projects in dermatology and cutaneous biology. This funding is aimed at junior investigators in the early stages of their academic careers who demonstrate a strong commitment to skin research. Eligible applicants must conduct research within ACGME-approved departments in the U.S. and must not have received funding from other sources for the same project.
Skin Diseases & Dermatology

Patient Directed Investigation Grant

Dermatology Foundation
Private
United States
US $25,000
The Patient Directed Investigation Grant by the Dermatology Foundation supports translational studies aimed at improving patient care in various dermatological fields. With an annual funding of $25,000, it fosters the career development of early-stage clinical investigators. Eligible applicants include those who have completed U.S. dermatology residency training and are not funded by other sources. The grant encourages diverse applicants, particularly from minority backgrounds, to contribute to vital health issues affecting underserved populations.
Skin Diseases & Dermatology Patient Care & Services

Medical Student Research Supplement Award

Dermatology Foundation
Private
United States
US $5,000
The Medical Student Research Supplement Award by the Dermatology Foundation supports medical students' research in dermatology, encouraging diversity and inclusion. This award offers $5,000 for direct research expenses, fostering the involvement of full-time students from underrepresented backgrounds. Eligible applicants must be current or former DF career development awardees and must recruit medical students pursuing MD or DO degrees who meet specific academic criteria. The award enhances research participation and strengthens the academic workforce in dermatology.
Diversity, Equity & Inclusion Skin Diseases & Dermatology

Dermatology Foundation: Career Development Awards

Dermatology Foundation
Private
United States
US $75,000
The Dermatology Foundation offers Career Development Awards to support the academic growth of emerging investigators in various dermatologic fields. With an annual stipend of $55,000, these awards foster research addressing significant health issues, including public health, diversity, and women's health. Eligible applicants must demonstrate strong institutional support and meet specific educational requirements. The awards can be renewed for up to three years, contingent on the recipient's progress and commitment to advancing dermatological science.
Skin Diseases & Dermatology Medical Education & Professional Training

Biogen Corporate Sponsorships

Biogen Foundation Inc.
Corporate
United States
Unspecified amount in in-kind support
Biogen Corporate Sponsorships provide funding to support congresses, events, and initiatives in exchange for tangible benefits such as marketing opportunities and recognition. Applications are reviewed on a rolling basis, and requests must be submitted 50 days in advance. Biogen considers various disease areas for sponsorship, including Alzheimer’s and Multiple Sclerosis. Approval depends on funding availability, alignment with interests, and event details, ensuring transparency for all potential sponsors.
Neurological Diseases & Disorders Dementia & Alzheimer’s Disease Chemistry +13 more

Voelcker Fund Grant

Max And Minnie Tomerlin Voelcker Fund
Private
United States
Unspecified amount
The Voelcker Fund Grant supports 501(c)(3) non-profit organizations conducting medical research, focusing on diseases like cancer and heart disease. It provides restricted grants, emphasizing research that seeks cures in the Greater Bexar County area, particularly for conditions affecting the retina. The fund prioritizes organizations in San Antonio and offers various funding structures, including seed and matching grants, while ensuring compliance with non-discrimination policies.
Heart Disease Cancer / Oncology Arthritis +2 more

Mission Boost Grants (MBG)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
US $100,000 - US $500,000
The Mission Boost Grants (MBG) by the American Cancer Society aim to enhance cancer research by funding projects that translate into human testing. These grants support investigators at all levels, offering resources for innovative clinical projects. The program consists of two funding stages: Stage I focuses on developing clear milestones for new treatments, while Stage II supports patient testing, ultimately contributing to advancements in cancer care and treatment.
Cancer / Oncology

Rheum for Kids: Pediatric Joint and Skin Disease Research Grant

Arthritis National Research Foundation
Private
United States
US $50,000 - US $250,000
The Rheum for Kids: Pediatric Skin and Joint Grant, offered by the Arthritis National Research Foundation, is aimed at early-career researchers focused on pediatric joint and skin diseases. This grant provides funding of up to $50,000 for one year to support innovative research projects. It encourages applications from diverse fields to advance the understanding and treatment of rheumatic diseases in children, fostering new insights and potential breakthroughs in pediatric healthcare.
Arthritis Children’s Health & Pediatrics Skin Diseases & Dermatology +2 more

Psoriatic Arthritis/Ankylosing Spondylitis Research Grant

Arthritis National Research Foundation
Private
United States
Up to US $250,000
The Arthritis National Research Foundation (ANRF) offers grants for research focused on Psoriatic Arthritis (PsA). With funding of up to $125,000 over two years, the ANRF encourages innovative projects that reveal the underlying mechanisms of PsA. Eligibility includes M.D. or Ph.D. qualifications and affiliation with a U.S. nonprofit research institution. Preference is given to senior post-doctoral researchers transitioning to independent status and new assistant professors. Applications without a Co-PI or those who have previously received ANRF funding will not be accepted.
Arthritis

Mentored Research Grants- Postdoctoral Fellowships (PF)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
Up to US $75,500
The American Cancer Society's Mentored Research Grants for Postdoctoral Fellowships (PF) aim to support emerging researchers in their training programs, fostering their transition to independent cancer research careers. Eligible candidates include US citizens or non-citizens with valid visas who have completed their doctoral degrees within the last four years. The fellowship offers funding for up to three years, with stipends of $66,000 to $70,000 annually, alongside allowances for health insurance and professional development.
Cancer / Oncology

Clinician Scientist Development Grant (CSDG)- Winter Cycle

American Cancer Society
Association/Society
American Samoa, Guam +4 more
US $405,000 - US $675,000
The Clinician Scientist Development Grant (CSDG) by the American Cancer Society supports full-time faculty aiming to become independent clinician scientists while maintaining clinical practice. Eligible applicants must hold a doctoral degree, an active clinical license, and have clinical care experience. The grant provides funding of $135,000 annually for 3 to 5 years, including allowable indirect costs, to advance cancer research in key priority areas.
Cancer / Oncology

ASTRO-ACS Clinician Scientist Development Grant (CSDG)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
US $405,000 - US $675,000
The American Cancer Society (ACS) and the American Society for Radiation Oncology (ASTRO) co-fund the Clinician Scientist Development Grant (CSDG), aimed at advancing the research careers of clinician scientists in radiation oncology. Eligible applicants are full-time faculty members at U.S. institutions with a doctoral degree and an active clinical license. The grant supports research for 3 to 5 years, providing $135,000 annually for direct costs, plus allowable indirect costs, while encouraging diversity in applications.
Cancer / Oncology

Institutional Research Grants (IRG)

American Cancer Society
Association/Society
American Samoa, Guam +4 more
Up to US $360,000
The Institutional Research Grants (IRG) program by the American Cancer Society provides essential seed funding for newly independent investigators to launch cancer research projects. Aimed at junior faculty, these grants offer $120,000 annually for three years, supporting the development of preliminary results necessary for competing for larger national grants. Eligible applicants must be at US academic institutions and hold the rank of Associate or Full Professor, with a proven track record in research and mentorship.
Cancer / Oncology

Health and Health Care Disparities Among Persons Living with Disabilities (R01 - Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Health and Health Care Disparities grant aims to support innovative research that addresses the health challenges faced by individuals with disabilities, particularly in communities experiencing health disparities. Key application deadlines span from February 2024 to October 2026. This funding opportunity invites research proposals that explore the underlying factors affecting the health and well-being of these populations, promoting interventions that can lead to significant improvements in health equity.
Health Disparities & Social Determinants of Health Disability Care & Services Disability Rights & Justice

PLTW Computer Science - New Program (Ameren)

Project Lead the Way inc.
Private
Adair County, Missouri, Adams County, Illinois +143 more
US $20,000

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

New Program

Computer Science & Engineering STEM / STEAM Education

PLTW Computer Science - Program Expansion (Ameren)

Project Lead the Way inc.
Private
Adair County, Missouri, Adams County, Illinois +143 more
US $10,000

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Computer Science & Engineering STEM / STEAM Education

PLTW Launch - New Program (Burns and McDonnell)

Project Lead The Way Inc
Private
Adams County, Colorado, Alamance County, North Carolina +300 more
Up to US $20,000
The PLTW Launch program, supported by Burns and McDonnell, aims to enhance student engagement in STEM education within eligible communities. This initiative will provide grants to schools that implement at least one PLTW Launch module in the 2025-2026 academic year, followed by another module in subsequent years. The program is designed to empower students with hands-on learning experiences that connect real-world challenges to essential skills, fostering a stronger future in STEM fields.
STEM / STEAM Education

Ewing Marion Kauffman Foundation: Sponsorship

Ewing Marion Kauffman Foundation
Private
Cass County, Missouri, Clay County, Missouri +2 more
US $1,000 - US $10,000
The Ewing Marion Kauffman Foundation offers sponsorships for events in the Kansas City area, with a focus on connecting people and supporting vital programs. Funding amounts range from $1,000 to $10,000, depending on event size and benefits. Organizations not currently funded by the Foundation are eligible to apply, with one request considered per year. Note that current grantees are ineligible, and sponsorships are not retroactive or recurring.
Racial / Ethnic Justice & Rights Economic Rights, Justice, & Mobility Education +4 more

ACLS Project Grants for HBCU Faculty

American Council of Learned Societies
Association/Society
United States
Up to US $10,000
The ACLS Project Grants for HBCU Faculty provide up to $10,000 to support early-stage project design and development over a 12- to 15-month period. This funding facilitates exploratory research and the advancement of existing projects, while offering networking and mentorship opportunities. Applicants must be employed at an HBCU and possess an MA or PhD in humanities or social sciences. The initiative encourages innovative research methods and community engagement, with a focus on higher education outcomes.
Humanities & Social Science

HBCU Faculty Fellowships

American Council of Learned Societies
Association/Society
United States
Up to US $50,000
The ACLS HBCU Faculty Fellowships provide financial support ranging from $30,000 to $50,000 for faculty at Historically Black Colleges and Universities to advance their research projects. The fellowships encourage innovative research outcomes, including scholarly articles and community-engaged projects. Awardees also benefit from mentoring and networking opportunities, with additional funding for their institutions to support humanities programming. This initiative promotes diverse scholarship and collaboration across disciplines, enhancing the academic landscape for HBCU faculty.
Humanities & Social Science

PLTW Launch - Program Expansion (Burns and McDonnell)

Project Lead The Way Inc
Private
Adams County, Colorado, Alamance County, North Carolina +300 more
US $5,000
The PLTW Launch program, in collaboration with Burns and McDonnell, aims to enhance STEM education by expanding access to innovative educational modules in eligible schools. This initiative supports public and charter schools in targeted counties, focusing on increasing student engagement in STEM fields. Through grant funding, participating schools can introduce new PLTW Launch modules and provide essential training for teachers, fostering a richer learning environment to prepare students for future careers in science, technology, engineering, and mathematics.
Teacher Development & Training STEM / STEAM Education

Lawren H. Daltroy Preceptorship in Health Communication

Rheumatology Research Foundation
Private
United States
Up to US $15,000
The Lawren H. Daltroy Preceptorship in Health Communication aims to enhance patient-clinician communication by providing a one-on-one learning experience for trainees and junior researchers. Funded by the Rheumatology Research Foundation, it offers up to $15,000 over one year for eligible candidates with no prior R01 funding. The program focuses on projects that improve understanding of effective communication in healthcare settings, addressing critical issues such as health literacy and shared decision-making.
Musculoskeletal Diseases Patient Care & Services Medical Education & Professional Training

Sanofi-Regeneron Diversity, Equity and Inclusion Mid-Career Award

Dermatology Foundation
Private
United States
Up to US $300,000
The Sanofi-Regeneron Diversity, Equity and Inclusion Mid-Career Award, funded by the Dermatology Foundation, supports exceptional researchers committed to addressing dermatological issues affecting underrepresented groups. Offering $100,000 annually for up to three years, this award emphasizes projects that enhance understanding and improve health equity in dermatology. Eligibility includes a strong research commitment, relevant training, and a faculty appointment within 12 years of becoming an Assistant Professor. It encourages minority applicants to foster diversity in medical research.
Diversity, Equity & Inclusion Skin Diseases & Dermatology

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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