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Best New York Grants for Nonprofits

Find nonprofit grants in New York, including opportunities in New York City, Buffalo, and Rochester. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.81B

Total funding

$5K

Median grant

10,000+ grants
$2.81B total
$5K median

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10,293 Results based on applied filters

NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) is designed to support clinical trial planning and implementation for dental, oral, and craniofacial conditions. This funding opportunity encourages applications that propose innovative research strategies within the NIDCR mission. Key deadlines span from February 2025 to January 2028, with emphasis on milestone-driven planning phases leading into possible clinical trial phases.
Dental Health Pharmacology Drug Safety +1 more

Rita Allen Foundation: Scholars Award in Pain

Rita Allen Foundation
Private
Canada, United States
US $150,000
The Rita Allen Foundation: Scholars Award in Pain supports early-career researchers in basic pain science. Established in 2009, it offers grants of $150,000 over three years to those investigating innovative pain mechanisms and analgesic development. Eligible candidates should be in the early stages of their faculty careers, demonstrating exceptional promise and a commitment to pain research. This award aims to enhance understanding and treatment of chronic pain, fostering impactful scientific advancements.
Anesthesia and Pain Medicine

Ken W. Davis Foundation Grant

Ken W Davis Foundation
Private
United States
More than US $10,000
The Ken W. Davis Foundation Grant provides essential funding to nonprofit organizations in the U.S. that align with the Foundation's mission of promoting basic human needs and education in line with Constitutional freedoms. With a minimum grant size of $2,500, the Foundation focuses on supporting human service organizations in Tarrant County, Texas, and the Permian Basin of West Texas and Southeast New Mexico, while also offering national support for grants related to Constitutional freedoms.
Governance & Democracy Human & Social Services Education System Policy & Reform

Apprenticeship Program

Alliance for California Traditional Arts
Private
United States
US $5,000
The ACTA Apprenticeship Program has been supporting California's cultural traditions for nearly 25 years by providing $5,000 contracts to mentor artists for intensive training of eligible apprentices. This program fosters the continuity of traditional arts through one-on-one mentorship, culminating in public presentations and documentation of the learning process. Eligible applicants must submit a collaborative application, demonstrating commitment and quality in their respective art forms. This initiative not only preserves cultural practices but also enhances community engagement.
Art & Culture Art Education

Igor Gorin Memorial Award

Community Foundation for Southern Arizona
Private
United States
Up to US $12,000
The Igor Gorin Memorial Award, established in 1993 by the Community Foundation for Southern Arizona, honors the legacy of Igor Gorin by supporting aspiring vocalists. With $382,000 awarded to 49 young talents, this fund provides unrestricted financial assistance for coaching, travel, and auditions. The 2026 award offers up to $12,000, aimed at those overcoming financial barriers to pursue operatic careers, ensuring that exceptional vocalists can thrive in their artistic journeys.
Opera

Community Collaboration Challenge

National Partnership for Student Success
Association/Society
United States
US $5,000 - US $10,000

Community Collaboration Challenge

Applications for the 2026 Community Collaboration Challenge are now open! With support from the Leon Lowenstein Foundation, the Challenge provides $5,000 – $10,000 awards to communities and is designed to support collaboration that expands and pilots evidence-based K-12 student supports in the form of high-impact tutoring, mentoring, student success coaching, postsecondary transition coaching, and/or wraparound/integrated student supports.

Tutoring & Mentoring College Success / Persistence

Smart Family Fund

Smart Family Fund
Private
United States
US $25,000 - US $100,000
The Smart Family Fund is a private foundation dedicated to supporting early-stage non-profits that demonstrate the potential for scalable, positive impact. With grants ranging from $25,000 to $100,000, they aim to assist organizations in refining their models and preparing for larger investments. The foundation, guided by three brothers, focuses on mentoring and backing social entrepreneurs facing challenges in securing funding for innovative yet untested ideas, fostering a brighter future for communities.
All fields of work Nonprofit Growth & Development

KeyBank Foundation Community Sponsorship

KeyBank
Corporate
Ada County, Idaho, Adams County, Colorado +203 more
Unspecified amount
The KeyBank Foundation offers Community Sponsorships to support local organizations in their fundraising efforts. These sponsorships range from $500 to $5,000 and can fund events or provide general operating support. Applications are accepted from January to October, with a decision made within 90 days. Eligible nonprofits must serve areas where KeyBank operates and adhere to strict ineligibility criteria, including no support for individuals or organizations that discriminate based on various identities.
Entrepreneurship Workforce Preparation & Job Readiness Community Development & Revitalization +11 more

The Rona Jaffe Foundation Fellowship

Fine Arts Work Center in Provincetown
Private
United States
More than US $2,500
The Rona Jaffe Foundation Fellowship supports emerging women writers with a fully funded 7-month residency at the Fine Arts Work Center. Established by the Rona Jaffe Foundation, it includes a $2,500 prize to assist with travel and living expenses. Eligible candidates must be U.S. residents, at least 18 years old, and not enrolled in a degree program during the fellowship year. This prestigious fellowship aims to nurture exceptional literary talent.
Writing & Literature

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity invites renewal applications for existing NINDS-supported clinical trial cooperative agreements (U01) that require additional time and resources. The National Institute of Neurological Disorders and Stroke (NINDS) expects applicants to request only what is necessary for trial completion, without introducing new aims. Discussions with NINDS prior to submission are encouraged. Eligible applications must be renewals of previously approved cooperative agreements under specified NIH funding announcements.
Neuroscience Neurological Diseases & Disorders Stroke

Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) (356879)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
This funding opportunity invites applications for pilot projects focused on understudied proteins linked to rare diseases. The goal is to generate preliminary data and tools related to these proteins, which belong to druggable families with known rare disease associations. By supporting innovative research, this initiative aims to facilitate the characterization of these proteins, ultimately contributing to advancements in understanding and treating rare diseases.
Human Genome & Genetics Rare Diseases

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This Funding Opportunity Announcement (FOA) aims to advance the identification and evaluation of candidate biomarkers for neurological and neuromuscular disorders. By facilitating the clinical development of neurotherapeutics, the FOA encourages research that includes both animal studies and preliminary human evaluations. The ultimate goal is to produce biomarkers ready for rigorous analytical and clinical validation, enhancing the effectiveness of treatments in clinical practice.
Biomedical informatics Neurological Diseases & Disorders Musculoskeletal Diseases

Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) (356887)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Limited Competition: Basic Instrumentation Grant (BIG) Program, supported by the NIH, invites applications from institutions that have not received significant S10 funding in recent years. This program provides a minimum award of $25,000 and allows for a maximum of $350,000 to purchase specialized instruments essential for NIH-supported research. Eligible instruments include cell sorters, confocal microscopes, and more, promoting advancements in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) (356886)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The Shared Instrumentation Grant (SIG) Program supports NIH investigators in acquiring high-cost, specialized instruments essential for research. With a minimum award of $50,000 and a maximum of $750,000, this program facilitates the purchase or upgrade of equipment like mass spectrometers and light microscopes. It encourages collaborative efforts among researchers to enhance capabilities and foster innovation in biomedical research.
Biology Health & Medicine Medical Technology, Devices, and Equipment

High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) (356883)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $5,000,000
The High-End Instrumentation (HEI) Grant Program, funded by the NIH, supports NIH-supported investigators in acquiring high-end, specialized instruments. With a minimum award of $750,001 and a maximum of $2,000,000, this program aims to enhance research capabilities. Eligible instruments include nuclear magnetic resonance spectrometers, mass spectrometers, and advanced imaging systems, among others. Applications are due by 5:00 pm local time of the applicant organization.
Medical Technology, Devices, and Equipment Health & Medicine Biotechnology +1 more

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) (356888)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The NIH is seeking innovative computational approaches to enhance the curation of biomedical research assets at scale. This initiative aims to accelerate access to secure datasets and computational models, facilitating transformative discoveries in biomedical science. Key deadlines for applications range from January 2025 to January 2027, covering standard, renewal, and AIDS-related grants. Applicants are encouraged to submit Letters of Intent 30 days prior to application deadlines to ensure a streamlined review process.
Biomedical informatics Epidemiology & Public Health Health Information Technology

Reboot Representation Grant

Reboot Representation Tech Coalition
Association/Society
United States
Unspecified amount
The Reboot Representation Tech Coalition aims to significantly increase the number of Black, Latina, and Native American women earning computing bachelor’s degrees. They invite qualified organizations to submit grant inquiries focused on recruiting and retaining these women in tech. Programs that leverage existing resources and operate across multiple regions will be prioritized, and the Coalition seeks initiatives backed by substantial research and community trust.
Computer Science & Engineering Diversity, Equity & Inclusion Women's Rights & Equality +4 more

Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $2,500,000
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program, funded by the NIH, aims to enhance the biomedical research landscape by supporting resource-limited organizations. It targets domestic institutions with limited research resources and few doctoral students in biomedical fields, promoting broader participation in research and boosting administrative capacities for sponsored programs. Applications are due by 5:00 PM local time of the applicant organization, ensuring timely submissions.
Biology Health & Medicine

Twin Tiers Christian Service Fund - Christian Holistic Living Grant

Community Foundation of Elmira-Corning and the Finger Lakes, Inc.
Private
Chemung County, New York, Schuyler County, New York +3 more
Up to US $2,500
The Twin Tiers Christian Service Fund offers the Christian Holistic Living Grant, providing up to $2,500 to support holistic and spiritual living initiatives in Chemung and adjacent counties. This grant aims to enhance community engagement through events and training in spiritual practices. Priority is given to programs promoting equity, community impact, collaboration, innovation, and sustainability. Organizations must be registered 501(c)3 or have a fiscal sponsor to be eligible.
Integrative & Alternative Health Health Care Access & Delivery Human & Social Services +4 more

HVAC Skills Lab Grant - Refurbish an Existing Plumbing or HVAC Skills Lab

Explore The Trades
Private
Canada, United States
Up to US $10,000
The HVAC Skills Lab Grant aims to refurbish existing plumbing and HVAC skills labs in middle and high schools across the U.S. and Canada. With a focus on preparing students for vital trade careers, the grant provides $10,000 in equipment to enhance hands-on learning. This initiative supports schools with technical training resources, promoting the growth of skilled labor in these essential fields. Schools that have not received a Skills Lab award in the past 24 months are eligible to apply.
Workforce Preparation & Job Readiness Vocational & Trade Education

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $5,000,000
The Environmental Health Sciences Core Centers Program (P30) invites grant applications to support innovative research in environmental health. These centers serve as critical hubs for advancing the goals of the 2025-2029 NIEHS Strategic Plan, providing essential infrastructure and resources for collaborative research. By fostering community engagement and translational research, the program aims to enhance understanding of the connections between environmental factors, human biology, and disease, ultimately improving public health outcomes.
Environmental Health

Impact100 Global Veterans Awards

Impact100 Global Veterans
Private
American Samoa, Guam +4 more
Up to US $100,000
The Impact100 Global Veterans Awards empower women to make a significant difference by awarding grants up to $100,000 to nonprofits that serve veterans. Focus areas include art and culture, education, health and wellness, environment, and family initiatives, promoting the well-being and support of veterans across the United States. Eligible organizations must meet specific criteria, including tax-exempt status, and are encouraged to submit proposals that utilize funds effectively within two years.
Art & Culture Military & Veterans Services Educational Access & Equity +17 more

Better Utilizing Investments to Leverage Development (BUILD) Grant Program

US Department of Transportation (USDOT)
Federal Government
American Samoa, Guam +4 more
Up to US $25,000,000
The BUILD Grant Program, managed by the USDOT, focuses on enhancing surface transportation infrastructure with substantial local impact. It supports a variety of project sponsors, including state and local governments, in pursuing complex multi-modal initiatives that are often challenging to fund through traditional grants. Established under the American Recovery and Reinvestment Act of 2009, this program reflects a commitment to sustainable and equitable infrastructure development.
Public Infrastructure Public Transportation & Mass Transit Systems

Weatherization Assistance Program

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Weatherization Assistance Program (WAP) by the U.S. Department of Energy provides essential services to improve energy efficiency in homes, particularly for low-income households. Eligible participants include those below 200% of the poverty level, renters, and homeowners. The application process involves determining eligibility, identifying local providers, and submitting necessary documentation. By helping families save on energy costs and enhancing comfort, WAP plays a crucial role in supporting vulnerable communities.
Homeownership Equitable & Affordable Housing Energy Efficiency & Conservation

TTP Bridge Program

US Department of Transportation: Federal Highway Administration (FHWA)
Federal Government
United States
Unspecified amount
The TTP Bridge Program aims to enhance the safety and accessibility of bridges in Tribal communities, addressing the urgent need for infrastructure improvements. With aging bridges affecting economic development and children's transportation, this program allows federally recognized Indian Tribes to apply for funding for planning, construction, and rehabilitation of bridges. By focusing on TTP bridges in poor condition, the initiative seeks to strengthen economic foundations and ensure better connectivity with markets, benefiting both families and communities.
Public Infrastructure Native American Services

Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) (357140)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (T32) supports eligible institutions in enhancing research training for predoctoral and postdoctoral candidates. This initiative aims to foster a diverse workforce in biomedical and clinical research, ensuring that training programs are comprehensive, engaging, and career-oriented. Key deadlines for applications are set from January 2025 through September 2027, with specific dates for standard and AIDS-related applications.
Science Biology Health & Medicine +1 more

Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) (357138)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $275,000
This funding opportunity from the NIH encourages groundbreaking research to enhance, develop, and preserve animal models and related biological materials for studies impacting human health. The program seeks innovative methodologies that can improve the diagnosis and management of diseases affecting animal use in biomedical research. Projects must demonstrate relevance across multiple NIH Institutes to align with broader research goals, emphasizing diverse body systems and disease categories.
Biology Diseases & Conditions

New York Grants for Nonprofits Highlights

New York grants for nonprofits provide funding to support education, urban development, environmental restoration, and public health programs. The following grants help organizations address local needs, promote equity, and enhance quality of life across New York communities.


Search Instrumentl's New York Grants Database


Explore 285 funding opportunities for nonprofits in New York, with $182.8M in resources. Instrumentl helps organizations secure funding by providing deadline alerts, refined search filters, and research-driven funder insights to foster sustainability and growth throughout the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : New York Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

300+ New York grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ New York grants for nonprofits over $25K in average grant size

100+ New York grants for nonprofits over $50K in average grant size

38 New York grants for nonprofits supporting general operating expenses

200+ New York grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Health & Medicine

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for New York grants for Nonprofits?

Most grants are due in the third quarter.

Q1
26.5%
Q2
21.7%
Q3
27.4%
Q4
24.4%

Typical Funding Amounts

What's the typical grant amount funded for New York Grants for Nonprofits?

Grants are most commonly $52,500.

$300 $300 Min.
$52,500 $52.5 K Median
$870,598 $870.6 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

New York nonprofits have access to a diverse range of funding opportunities to fit their needs. With over 300+ unique grants available, organizations can explore a total of $182,825,591 in funding. The median grant award in New York is $52,500. For nonprofits looking to apply for larger grants, 100+ grants surpass $25,000. The majority of funding opportunities in New York support programs and project-based initiatives. However, 38 grants specifically help cover general operating expenses.

Nonprofits in New York have access to diverse funding sources, including corporate foundations, professional associations, and government-sponsored grants. Here’s a summary of key types of funders:

  • Private funders: Private foundations offer the majority of funding opportunities in New York. Currently, more than 118 foundation grants are available to support areas like military and veteran services, education, and social justice.
  • State and Local Governments: New York’s state and local governments provide funding for key initiatives, particularly in farming, animal welfare, and sustainable agriculture.
  • Federal government: Federal grants contribute significantly to land preservation in New York’s nonprofit sector by focusing on environmental education, climate change resilience, and water resource management.

Whether you go after government grants or foundation grants depends on your grant readiness. Keep in mind that government grants often have large awards but equally large compliance requirements.

New York nonprofits can apply for grants steadily over the course of the entire year; however, there are certain peak periods. Q3 is the best time to submit applications as 27.4% of grant deadlines fall during this time. Q1 and Q4 follow behind, accounting for 26.5% and 24.4% of grant deadlines, respectively. In contrast, Q2 is the slowest period, with only 21.7% of grants accepting applications. Keeping this data in mind could be crucial in securing a funding opportunity rather than missing out for the quarter.

Grant funding in New York has remained stagnant over the past several years. Based on IRS funding reports, total grant funding reached $28 billion in 2021 but remained $28 billion in 2022. However, future funding opportunities look optimistic. The key focus areas for grants in New York included private grant-making organizations, professional societies and associations, and finally, alliance/advocacy organizations. The counties that have previously received the most funding are New York County, Kings County, and Nassau County.

For those interested in diving deeper, check out our New York Private Grants Landscape report that unpacks the funding disparities between urban and rural counties.

Finding the right grant in New York might seem overwhelming, but Instrumentl is here to help. The platform streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in your state. Aside from tracking the latest opportunities, Instrumentl also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

Check out Instrumentl’s platform.

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