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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,706 Results based on applied filters

NBRC Gareth B. Gish, MS, RRT Memorial Postgraduate Education Recognition Award

American Respiratory Care Foundation
Private
United States
Up to US $5,000
The NBRC Gareth B. Gish Memorial Postgraduate Education Recognition Award, offered by the American Respiratory Care Foundation, honors the legacy of Gareth B. Gish, a pioneer in respiratory care. This award supports respiratory therapists pursuing advanced degrees, providing up to $5,000 in funding, along with recognition, airfare, lodging, and Congress registration. Established in 1999, it seeks to nurture future leaders in the field, continuing Mr. Gish's commitment to education and excellence in respiratory care.
Respiratory Diseases & Systems

William F. Miller, MD Postgraduate Education Recognition Award

American Respiratory Care Foundation
Private
United States
Up to US $5,000
The William F. Miller, MD Postgraduate Education Recognition Award, offered by the American Respiratory Care Foundation, provides up to $5,000 to support respiratory therapists pursuing advanced degrees. Established in 1992, this award aims to foster education and professional growth in respiratory care. Recipients also receive recognition, airfare, lodging, and congress registration. Eligible applicants must meet specific educational and recommendation requirements, ensuring that deserving candidates are selected for this prestigious award.
Respiratory Diseases & Systems

Jeri Eiserman, RRT Professional Education Research Fellowship

American Respiratory Care Foundation
Private
United States
Unspecified amount in in-kind support
The Jeri Eiserman, RRT Professional Education Research Fellowship, funded by the American Respiratory Care Foundation, supports innovative research in respiratory care and airway management. This fellowship honors Jeri Eiserman's contributions to the field and includes awards for high-quality abstracts presented at the AARC Congress. Selected fellows receive a plaque, travel expenses, and registration, promoting advancements in respiratory health through research and education.
Respiratory Diseases & Systems

JetBlue Foundation Grants

Jetblue Grants Foundation
Corporate
Ada County, Idaho, Albany County, New York +115 more
Up to US $50,000
The JetBlue Foundation is dedicated to enhancing aviation-related education and STEM initiatives, aiming to inspire future aviation leaders. Offering grants up to $50,000, it supports educational organizations that focus on aviation technology, engineering, operations, and maintenance. The foundation prioritizes programs benefiting under-represented communities in aviation, including veterans, women, and diverse groups, ensuring a broader range of voices in the industry.
Aviation STEM / STEAM Education

J.B. Hunt Transport Services: Company Giving

J.B. Hunt Transport Services
Corporate
United States
Unspecified amount
J.B. Hunt Transport Services offers financial support for various community projects through its Company Giving program. Focused on four key areas—Health Care, Veterans' Support, Education, and Crisis Management—this initiative aims to enhance the well-being of local communities. Eligible applicants include 501(c)(3) organizations, schools, and civic groups, while organizations that primarily benefit their members or have high management overhead may be excluded. The program underscores J.B. Hunt's commitment to corporate social responsibility.
Health Care Access & Delivery Military & Veterans Services Education +1 more

Domtar Community Investment Grant

Domtar
Corporate
United States
Unspecified amount
The Domtar Community Investment Grant supports nonprofits and charities in areas where the company operates, focusing on education, environmental sustainability, and community humanitarian needs. Eligible organizations include charitable groups, while ineligible entities encompass individuals, discriminatory organizations, and political causes. Applications are accepted online from January 1 to November 30, with reviews conducted bi-monthly. This initiative aims to create meaningful connections between charitable efforts and the social benefits derived from Domtar's business operations.
Education Environment Disaster Relief / Humanitarian Aid +1 more

Alleghany Foundation Grants

Alleghany Foundation
Private
United States
Unspecified amount
The Alleghany Foundation, a private 501(c)(3) organization in Virginia, focuses on enhancing the quality of life in the Alleghany Highlands through strategic funding initiatives. It seeks grant applications that address key areas such as economic transformation, educational excellence, health and wellness, community capacity, and civic leadership. By prioritizing innovative projects and supporting local organizations, the Foundation aims to foster sustainable growth and community engagement, ensuring a vibrant future for the region.
Business Development Entrepreneurship Academic Success & Enrichment +11 more

STEM Innovation Grant

Colocation America
Corporate
United States
US $1,500 - US $7,500
The STEM Innovation Grant by Colocation America supports innovative STEM programs for K-12 students, offering up to $7,500 in funding. Eligible applicants include nonprofit organizations and schools with STEM-specific programming. The grant aims to inspire youth through unique learning approaches and real-world applications of STEM knowledge. Interested parties must attend a mandatory informational call, with funding available for tools, curriculum development, and professional training.
STEM / STEAM Education

AFE Educational Grants

American Floral Endowment (AFE)
Private
United States
US $500 - US $10,000
The American Floral Endowment (AFE) offers educational grants aimed at enhancing the floriculture industry through innovative programs. With over $3 million funded since its inception, AFE supports initiatives targeting young people and addressing industry challenges. Grants range from $500 to $10,000 annually, encouraging multi-year projects that benefit broad geographical areas. Eligible applicants include community organizations focused on floriculture education within the U.S. AFE prioritizes programs with national scope and significant educational impact.
Horticulture & Gardening Education

Alzheimer's Disease Research Grants

BrightFocus Foundation
Corporate
United States
US $200,000 - US $300,000
BrightFocus Foundation offers Alzheimer's Disease Research Grants to support innovative research aimed at understanding, preventing, and treating Alzheimer's disease. These grants encourage applications from diverse backgrounds, fostering creativity in scientific research. The program includes Standard Awards for early investigators with a maximum funding of $300,000 for three years and Postdoctoral Fellowship Awards for young researchers at $200,000 for two years, promoting the development of independent research careers.
Dementia & Alzheimer’s Disease

National Glaucoma Research RFP: Standard Awards

BrightFocus Foundation
Corporate
United States
Up to US $150,000
The National Glaucoma Research Program, funded by BrightFocus Foundation, aims to support groundbreaking research in glaucoma. Established in 1978, the program has awarded over $35 million to 32 projects focusing on understanding and treating this disease. The Standard Awards provide $150,000 over two years for researchers with preliminary data to further their work. Eligible institutions must be non-profit and demonstrate their tax-exempt status to receive funding, fostering innovative solutions for glaucoma treatment.
Eye Diseases & Disorders

Michael & Susan Dell Partnerships

Michael & Susan Dell Foundation
Private
Africa, India +2 more
Unspecified amount
The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.
Poverty Alleviation & Services Education - Preschool / Early Learning Education - K through 12 +4 more

Brinker International Charitable Giving Program

Brinker International
Corporate
Acadia Parish, Louisiana, Ada County, Idaho +620 more
Unspecified amount
The Brinker International Charitable Giving Program focuses on giving back to communities through support for kids, hunger, and education. Organizations eligible for funding must be 501c(3) non-profits and submit requests at least six weeks prior to events. The program does not support individuals, political or religious organizations, or explicit discrimination policies. Funding is provided through monetary donations or in-kind contributions like dining certificates.
Food Access & Hunger Youth Services Children’s Health & Pediatrics +5 more

The Standard's Corporate Giving Program

The Standard Charitable Foundation
Corporate
United States
US $500 - US $25,000
The Standard's Corporate Giving Program emphasizes community support and employee engagement, reflecting its foundational mission to enhance financial well-being. Established in 1906, the program focuses on Healthy Communities, Disability and Empowerment, Cultural Development, and Education. With a funding range of $500 to $25,000, it aims to make a substantial impact in the lives of individuals and families facing challenges. The Standard Charitable Foundation, launched in 2006, further extends this commitment by supporting organizations that align with its philanthropic goals.
Workforce Preparation & Job Readiness Education - Preschool / Early Learning Basic Human Needs +12 more

Penn National Gaming Foundation Grants

Penn National Gaming
Corporate
Berks County, Pennsylvania, Camden County, Missouri +32 more
Unspecified amount
The Penn National Gaming Foundation Grants support various community initiatives across North America, emphasizing education, health services, and cultural affairs. Launched post-Hurricane Katrina, the foundation aids local nonprofits, enhancing community development, public safety, and veteran support. The grants cater to organizations that address the needs of children, senior citizens, and disadvantaged populations, ensuring a broad impact in areas where Penn National Gaming operates. This commitment reflects the foundation's dedication to uplifting communities and fostering resilience.
Community / Public Safety Diversity, Equity & Inclusion Education - K through 12 +9 more

Caleres Cares Charitable Trust Grants

Caleres Cares Charitable Trust
Corporate
St. Louis City, Missouri, St. Louis County, Missouri
Unspecified amount
The Caleres Cares Charitable Trust Grants support 501(c)(3) tax-exempt non-profit organizations that align with the Trust's mission to promote stronger families, diversity, and sustainability. Established in 1921, the Trust focuses on enhancing the St. Louis community, supporting arts and culture, and fostering corporate responsibility. Grants are not available for discriminatory organizations or individual requests, ensuring funds are directed towards impactful community initiatives.
Art & Culture Family Services Diversity, Equity & Inclusion +1 more

Edwards Lifesciences Foundation Grants

Edwards Lifesciences Foundation
Private
United States
Unspecified amount
The Edwards Lifesciences Foundation Grants program aims to improve the health of underserved communities by supporting initiatives focused on education, screening, and treatment of cardiovascular disease. The Foundation seeks to enhance care access for patients, promote awareness of heart health, and foster community engagement through volunteer opportunities. By 2025, the goal is to positively impact the lives of 2.5 million patients affected by structural heart issues. The program emphasizes collaboration and innovation in healthcare.
Cardiovascular Diseases & Systems

Gibson Foundation Donation Request

Gibson Gives
Private
United States
Unspecified amount
The Gibson Foundation, now known as Gibson Gives, is dedicated to enhancing lives through music by supporting 501(c)(3) organizations. Their mission is to inspire and amplify the power of music through guitars for all generations. With a commitment to music education and wellness, Gibson Gives is making a positive impact worldwide, ensuring that music continues to shape the lives of musicians and enrich communities. Donations are reviewed monthly, requiring a minimum of four weeks for processing.
Music Education

BISSELL Pet Foundation: Partners for Pets

Bissell Pet Foundation
Private
United States
Unspecified amount
BISSELL Pet Foundation's Partners for Pets program supports over 6,025 animal welfare organizations across the U.S. by providing resources aimed at reducing homeless animals through adoption, spay/neuter initiatives, and emergency support. Eligible organizations must be 501(C)(3) nonprofits or local government entities engaged in animal welfare, fostering community connections and financial assistance during crises. This initiative not only benefits shelters but also enhances partnerships among various animal welfare groups, promoting a united effort to improve animal lives.
Animal Welfare - Domestic Animals & Pets

Natural Disaster Response Grants

PetSmart Charities
Private
Canada, United States
Unspecified amount
PetSmart Charities offers Natural Disaster Response Grants to support organizations addressing the urgent needs of pets affected by major disasters. Grant funds can be utilized for shelter supplies, veterinary care, structural repairs, and supplemental staff expenses within 30 to 45 days post-disaster. In special cases, funding may extend up to 60 days. Eligible applicants include authorized disaster responders and nonprofit organizations directly impacted by the disaster, ensuring timely assistance to affected animals and their caretakers.
Animal Welfare - Domestic Animals & Pets

Adoption Partnerships - Adoption Rewards & Adoption Event Grants

PetSmart Charities
Private
Canada, United States
Up to US $250,000
PetSmart Charities' Adoption Partnerships and Event Grants support organizations in finding loving homes for pets. With over 10 million pets placed, the program offers resources like cash rewards for adoptions and grants for event support. Eligible partners include registered charities and educational institutions. The maximum grant available is $5,000, aimed at maximizing the impact of adoption events. Join us in enhancing the lives of pets and their new families through collaboration and community engagement.
Animal Welfare - Domestic Animals & Pets

Ittleson Foundation: Mental Health Grant Program

Ittleson Foundation
Private
United States
Unspecified amount
The Ittleson Foundation, established in 1932, focuses on enhancing mental health, AIDS prevention, and environmental initiatives. It funds not-for-profit organizations aiming to improve public policy and the lives of citizens. The Foundation is particularly interested in innovative projects addressing mental health stigma, advancing preventative efforts, and supporting underserved populations. While it funds new initiatives, it does not typically support capital projects, endowments, or direct service programs outside New York City.
Mental Health & Psychiatric Diseases

Conagra Brands Foundation- Community Impact Grants

Conagra Brands Foundation
Corporate
United States
Unspecified amount
The Conagra Brands Foundation offers Community Impact Grants to nonprofit organizations in the USA that address food insecurity and promote healthy lifestyles. Eligible organizations must align with core focus areas like food access, nutrition education, and cooking skills. Grants support initiatives that foster community engagement and provide entrepreneurial skills. Nonprofits must uphold a non-discrimination policy protecting various characteristics. Applications are accepted through a Letter of Intent from January 1 to February 15, 2025.
Food Access & Hunger Agriculture Nutrition & Healthy Eating

AAD Annual Meeting Registration Scholarship Program

American Academy of Dermatology
Association/Society
United States
Unspecified amount
The AAD Annual Meeting Registration Scholarship Program offers scholarships to international dermatologists, excluding those from the U.S. and Canada, to support their attendance at the AAD's Annual Meeting. Each country can nominate up to two applicants, who will receive complimentary registration, access to a post-graduate session, and an invitation to the International Scholarship Recipient Reception. This initiative promotes global participation in dermatology.
Skin Diseases & Dermatology

Clarence S. Livingood, MD, Memorial Award and Lectureship

American Academy of Dermatology
Association/Society
United States
US $10,000
The Clarence S. Livingood, MD, Memorial Award and Lectureship recognizes outstanding contributions to dermatology. Established by the Department of Dermatology at Henry Ford Hospital, it honors Dr. Livingood's legacy. The award includes a $10,000 cash prize and the opportunity to present a lecture at the AAD Annual Meeting. Nominations are accepted annually until January 15, remaining active for five years, and are open to experts beyond dermatologists, emphasizing communication and expertise in relevant issues.
Skin Diseases & Dermatology

Everett C. Fox, MD, Memorial Lectureship

American Academy of Dermatology
Association/Society
United States
US $10,000
The Everett C. Fox, MD, Memorial Lectureship honors a distinguished dermatologist and offers a $10,000 award to the selected lecturer, who will present a 30-minute lecture at the AAD's Innovation Academy. Nominations are open until June 15 for the upcoming selection cycle, with entries held for five years. Candidates must be practicing clinical dermatologists with proven communication skills, ensuring the recognition of expertise within the field.
Skin Diseases & Dermatology

AAD Young Investigator Awards

American Academy of Dermatology
Association/Society
Canada, United States
US $6,000
The AAD Young Investigator Awards recognize promising dermatology researchers in the U.S. and Canada, offering a $6,000 prize and plaque for outstanding research in either basic/translational or clinical tracks. Eligible applicants must have a DO, MD, or PhD, and their research should be completed and submitted for publication. The application window is open from June 1 to September 1, encouraging diversity within research topics and applicants.
Skin Diseases & Dermatology

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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