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Best Missouri Grants for Nonprofits

Find nonprofit grants in Missouri, including opportunities in St. Louis, Kansas City, and Springfield. Updated listings for 501(c)(3) organizations statewide.

10,000+

Available grants

$2.60B

Total funding

$5K

Median grant

10,000+ grants
$2.60B total
$5K median

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9,706 Results based on applied filters

Rockefeller Family Fund: Climate Grant

Rockefeller Family Fund
Private
United States
Unspecified amount
The Rockefeller Family Fund's Climate Grant focuses on reducing fossil fuel production to combat climate change. It supports initiatives that hold polluters accountable and fosters citizen engagement for climate action. The fund prioritizes programs that seek to limit oil and gas production, enforce climate damages in court, and promote sustainable energy solutions. By addressing the fossil fuel industry's resistance, the grant aims to create meaningful progress towards climate goals and ensure that those responsible for climate disruption contribute to adaptation efforts.
Environmental Justice & Advocacy Environmental Policy

Kettering Family Foundation Grant

Kettering Family Foundation
Private
United States
Unspecified amount
The Kettering Family Foundation, established in 1956, supports diverse charitable activities across various sectors, including arts, education, health, and human services. Applicants must have a valid 501(c)(3) status and discuss proposals with foundation staff before applying. Only one application is allowed per year, and specific exclusions apply, such as for religious purposes and individual grants. The foundation emphasizes meaningful community impact, making it a vital resource for eligible organizations.
Environment Education Art & Culture +4 more

Adolph Coors Public Policy Grant Programs

Adolph Coors Foundation
Private
United States
Unspecified amount
The Adolph Coors Public Policy Grant Programs support organizations that embody western values like self-reliance and personal responsibility. The Foundation prioritizes initiatives that promote youth prosperity, economic opportunities for adults, and public policies reflecting America’s founding principles. Eligible applicants must be 501(c)(3) organizations, with a focus on rural Colorado nonprofits. The Foundation does not fund projects in areas such as arts, health, or international components, ensuring a clear alignment with its mission.
Public Policy

APAF: Jeanne Spurlock, M.D. Minority Fellowship Achievement Award

American Psychiatric Association
Private
United States
Unspecified amount
The APAF: Jeanne Spurlock, M.D. Minority Fellowship Achievement Award, established in 1999, acknowledges the significant contributions of former fellows of the Minority Fellowships to the psychiatry profession and the minority community. This award promotes continued engagement in the fellowship program while honoring Dr. Jeanne Spurlock, the program's founder. It aims to enhance psychiatric education, improve access to quality care, and support the professional needs of its members, fostering collaboration in mental health fields.
Mental Health & Psychiatric Diseases

Gladys Brooks Foundation Grants

The Gladys Brooks Foundation
Private
United States
US $50,000 - US $150,000
The Gladys Brooks Foundation supports innovative projects in libraries, education, hospitals, and clinics. Grants focus on resource endowments, capital construction, and equipment aimed at improving public access to information and educational resources. Eligible applicants must be 501(c)(3) organizations located in specific states and demonstrate that projects will be funded primarily by the grant. Applications for direct salary support or research projects are not accepted.
Education - Higher Education Health Facilities & Clinics Library Services +6 more

Empowerment Grants

The Hanger Charitable Foundation
Corporate
United States
Up to US $20,000
The Hanger Foundation's Empowerment Grants aim to positively impact individuals with physical challenges by supporting 501(c)(3) organizations in the U.S. The foundation focuses on rehabilitation services, athletic programs, and social activities that empower those with limb loss or differences. Grants are available for one year and prioritize projects that engage communities and enhance the quality of life for those in need. Organizations are encouraged to apply for funding that directly supports these goals.
Diabetes Cardiovascular Diseases & Systems Medical Rehabilitation +3 more

John Ben Snow Memorial Trust Grant

John Ben Snow Memorial Trust
Private
United States
US $5,000 - US $20,000
The John Ben Snow Memorial Trust Grant supports educational programs and initiatives that assist individuals demonstrating financial need. Founded in 1975, it prioritizes funding for organizations that enhance educational opportunities, arts, culture, and community initiatives, particularly for youth and disadvantaged populations. The Trust encourages proposals from 501(c)(3) organizations, with grants typically ranging from $10,000 to $20,000. It also considers limited proposals in disabilities, environmental protection, and historic preservation, focusing on educational impact.
Community Development & Revitalization Historic Preservation Disability Care & Services +22 more

WRRC Research Grants

Washington Red Raspberry Commission
State/Local Government
United States
Unspecified amount
The Washington Red Raspberry Commission offers research grants to support the advancement of red raspberry cultivation. These grants focus on innovative farming practices, pest management, and cultivar development, aimed at enhancing grower productivity and sustainability. Proposals are evaluated based on their potential impact on the industry, with an emphasis on practical applications. The commission invites researchers from various backgrounds to contribute, ensuring a diverse range of solutions for the challenges faced by raspberry growers.
Agricultural Crops

CHEJ Small Grants Program

Center for Health, Environment & Justice
Private
United States
Unspecified amount

CHEJ Small Grants Program

The Small Grants Program has officially relaunched. Applications are now open.The Center for Health, Environment & Justice’s (CHEJ) Small Grants Program is for grassroots groups working on environmental health and justice issues related to the presence of “toxics” (toxic chemicals or hazardous substances) in their immediate communities. CHEJ prioritizes community-based organizations aiming to have local, state and regional impact through their own strategies and actions.

Environmental Health Environmental Justice & Advocacy

Environmental Grantmaking Program at EFA

Educational Foundation of America
Private
United States
Unspecified amount
The Environmental Grantmaking Program at the Educational Foundation of America (EFA) aims to support projects that facilitate a transition to a net-zero electricity system. Focused on reducing greenhouse gas emissions, the program emphasizes initiatives that enhance access to affordable clean energy, accelerate regional transitions, and strengthen financial investment in electric utilities. Eligible applicants include 501(c)3 public charities, academic institutions, and government entities committed to sustainable energy solutions.
Environmental Justice & Advocacy Environmental Economics Renewable/Sustainable Energy

Dorsey & Whitney Foundation Grant

Dorsey & Whitney Foundation
Private
North America
Unspecified amount
The Dorsey & Whitney Foundation Grant supports charitable initiatives in communities where Dorsey attorneys reside. Established in 1982, it focuses on organizations that provide legal services to the disadvantaged and engages attorneys in volunteer roles. Each year, around 200 direct grants are awarded across North America, alongside additional support for numerous other organizations through a matching program. This commitment highlights the foundation's dedication to cultural, civic, educational, and social welfare.
Community Culture & Heritage Civic Affairs Education +2 more

Caesars Regional & Property Giving

The Caesars Foundation
Private
Amador County, California, Atlantic County, New Jersey +31 more
Unspecified amount
The Caesars Foundation supports community-focused organizations through monetary and in-kind donations, prioritizing strategic areas like social equity, climate action, and mental health. Eligible applicants include IRS-recognized nonprofits and educational institutions operating within the U.S. Requests must align with these focus areas to enhance community impact. Organizations that discriminate or operate outside the U.S. are ineligible. By fostering collaboration, the foundation aims to uplift vulnerable populations and promote sustainable practices.
Climate Change Resilience & Equity Food Security Human Trafficking +17 more

Seeds For Stewardship Grant

CHS Foundation
Corporate
United States
Up to US $10,000
The Seeds For Stewardship Grant by the CHS Foundation aims to enhance agricultural leadership and improve rural community safety. This initiative supports member cooperatives and local organizations with matching grants, fostering innovative projects that benefit rural America. Eligible applicants can receive up to $10,000 annually, promoting priority areas such as agricultural education and farmer well-being. The program has positively impacted over 200 communities, reinforcing the importance of collaboration and community investment in rural development.
Agriculture

Sustainable Development Grant Program

The Rockefeller Brothers Fund
Private
Bosnia and Herzegovina, China +3 more
Unspecified amount
The Sustainable Development Grant Program, funded by The Rockefeller Brothers Fund, aims to combat climate change by promoting ecological stewardship, economic viability, and social equity. It supports initiatives that enhance public understanding, implement clean energy solutions, and foster international cooperation. The program prioritizes projects that address the urgent threats posed by climate change while ensuring that development efforts are sustainable and inclusive for future generations.
Sustainability Climate Change Resilience & Equity Environmental Economics

Kalliopeia Foundation Grant

Kalliopeia Foundation
Private
United States
Unspecified amount
The Kalliopeia Foundation Grant focuses on supporting projects that foster cultural and ecological renewal through a deep reverence for the Earth. By prioritizing US-based organizations that demonstrate strong community relationships and intergenerational leadership, the foundation seeks to empower marginalized voices and traditional practices. With an emphasis on land care and Indigenous leadership, Kalliopeia aims to cultivate a resilient future where diverse ways of knowing and being thrive harmoniously with nature.
Science Communications Environment Ecology +7 more

LREC: Research Grants

Missouri Botanical Garden
Private
St. Louis County, Missouri
Up to US $1,000
The Litzsinger Road Ecology Center (LREC) is offering up to 3 research grants for undergraduate or graduate students, faculty, or professional researchers focused on ecology, conservation, or environmental science. Grants of up to $1000 are available, with potential for more funding for extensive research. Funds can support supplies, travel, stipends for data collection, and conference attendance. Preference is given to projects aligning with LREC's research goals.
Environmental Conservation Ecology

McKnight Endowment Fund for Neuroscience: Neurobiology of Brain Disorders Award

The McKnight Foundation
Private
United States
Up to US $300,000
The McKnight Endowment Fund for Neuroscience offers the Neurobiology of Brain Disorders Award to support innovative research aimed at understanding and treating brain disorders. It provides up to four awards of $100,000 each year for three years, encouraging proposals that explore biological mechanisms and environmental contributions to neurological disorders. The program emphasizes inclusivity and collaboration among researchers to advance the field and improve therapeutic interventions for conditions such as Alzheimer's and Parkinson's disease.
Neuroscience Neurological Diseases & Disorders Mental Health & Psychiatric Diseases

Family Medicine Leads Scholarships for FUTURE- Early Career Student (Rising MS/OMS 1–3)

American Academy of Family Physicians Foundation
Corporate
Jackson County, Missouri
US $600
The Family Medicine Leads Scholarships support early career medical students (MS/OMS 1-3) to attend the AAFP FUTURE National Conference. With over 5,175 scholarships awarded since 2002, totaling over $2.3 million, this initiative aims to enhance students' commitment to family medicine. Applicants must be AAFP members and complete an online application, including essay questions. The $600 scholarship helps cover conference-related expenses, and attendance is mandatory to receive the funds.
Primary Health Care Medical Education & Professional Training

Family Medicine Cares- USA Free Health Clinics Grants ( New Clinics)

American Academy of Family Physicians Foundation
Corporate
United States
Up to US $25,000
The Family Medicine Cares USA Free Health Clinics Grants support new and existing clinics in the U.S. that provide care to the uninsured. With applications accepted annually from March 15 to July 15, these grants assist clinics in purchasing essential medical equipment. The initiative aims to address the needs of over 50 million uninsured individuals, ensuring access to primary care and promoting volunteerism among AAFP members and medical students. Grants of up to $10,000 are available to eligible clinics.
Health Facilities & Clinics

ECMC Foundation: Grants & Investments

ECMC Foundation
Private
Puerto Rico, United States
Unspecified amount
The ECMC Foundation focuses on eliminating equity gaps in postsecondary education by 2040 through strategic grantmaking and investments. They support organizations aiming to remove barriers to completion, build institutional capacity, and transform the postsecondary ecosystem. Eligible entities include nonprofit organizations, government entities, and postsecondary institutions. However, funding is not available for personal scholarships, political activities, or projects outside the U.S. that do not align with the Foundation's mission of diversity and inclusion.
College Success / Persistence Career / College Preparation Education - Higher Education +1 more

Paul L. Busch Award

Water Research Foundation
Private
United States
Up to US $100,000
The Paul L. Busch Award, provided by the Water Research Foundation, honors individuals for innovative research in water quality. This prestigious award supports promising researchers with a $100,000 grant to advance their work. The selection process is inclusive, with no restrictions based on race, gender, or nationality, and encourages applications from diverse candidates. Recipients are expected to collaborate with U.S.-based organizations, fostering practical applications of their research in the water environment.
Sanitation & Clean Drinking Water Water Resource Management Freshwater Conservation

Oklahoma City Community Foundation: Kirschner Trusts Grant

Oklahoma City Community Foundation
Private
United States
Up to US $40,000
The Oklahoma City Community Foundation administers the Kirschner Trusts, established to honor Phil and Roberta Kirschner's philanthropic legacy. These trusts focus on supporting young individuals with disabilities, Muskogee nonprofits, and Jewish causes. Since their transfer to the foundation in 2013, the trusts have continued to provide vital grants to organizations that align with the Kirschners’ values, ensuring their charitable impact persists in the community.
Youth Services Education Disability Care & Services +4 more

Infinite Hero Foundation Grant Program

Infinite Hero Foundation
Private
United States
Up to US $100,000
The Infinite Hero Foundation Grant Program supports military personnel and their families by funding innovative treatment programs for service-related injuries. Since 2012, it has awarded over $5.7 million to 51 organizations focused on physical rehabilitation, mental health, leadership development, family support, and suicide prevention. Grants up to $100,000 are available for programs that align with the foundation's mission, ensuring that funds directly support program costs and not administrative expenses.
Military & Veterans Services Post-Traumatic Stress Disorder

Eastman Foundation Grants

Eastman Foundation
Corporate
Galveston County, Texas, Gregg County, Texas +10 more
Unspecified amount
The Eastman Foundation Grants promote corporate social responsibility by enhancing the quality of life through sustainable community improvement. By partnering with nonprofit organizations, the foundation focuses on economic success, social well-being, and environmental integrity. The foundation emphasizes creating diverse and inclusive communities, addressing human needs while minimizing environmental impact. Grants are available for qualified organizations that align with these goals, ensuring that funding supports initiatives that foster healthy, vibrant communities where both people and nature can thrive.
Economic Services & Development Community Services Basic Human Needs +1 more

MWDSC: Innovative Conservation Program Funding

The Metropolitan Water District of Southern California
State/Local Government
United States
Up to US $50,000
The Metropolitan Water District of Southern California's Innovative Conservation Program (ICP) has funded innovative water savings projects since 2001, with $250,000 available biannually. The program aims to evaluate and demonstrate the reliability of new water-saving technologies. Nearly 400 proposals have sought $36 million in funding. The ICP, supported by multiple agencies, encourages projects that can benefit Southern California's water efficiency, inviting proposals from outside its service area to enhance regional water management.
Water Resource Management

Missouri Grants for Nonprofits Highlights

Missouri grants for nonprofits provide funding to support education, healthcare, rural development, and community engagement programs. The following grants empower organizations to tackle local challenges, enhance sustainability, and improve quality of life across Missouri.


Search Instrumentl's Missouri Grants Database


Discover 136 funding opportunities for nonprofits in Missouri, with $47.6M available. Instrumentl supports organizations with strategic grant discovery, deadline tracking tools, and funder insights to drive impactful programs across the state.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Missouri Grants for Nonprofits

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

100+ Missouri grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

37 Missouri grants for nonprofits over $25K in average grant size

29 Missouri grants for nonprofits over $50K in average grant size

25 Missouri grants for nonprofits supporting general operating expenses

100+ Missouri grants for nonprofits supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Missouri grants for Nonprofits?

Most grants are due in the first quarter.

Q1
33.7%
Q2
26.8%
Q3
18.7%
Q4
20.8%

Typical Funding Amounts

What's the typical grant amount funded for Missouri Grants for Nonprofits?

Grants are most commonly $13,750.

$375 $375 Min.
$13,750 $13.8 K Median
$587,301 $587.3 K Average
$40,331,313 $40.3 M Max.

Frequently asked questions

Missouri nonprofits have access to a vast selection of funding opportunities. Currently, more than 100+ unique grants are available, with a total of $47,571,363 in funding. The median grant award in Missouri is $13,750. Of these opportunities, 37 grants exceed $25,000, with 25 grants funding general operating expenses and 100+ grants funding specific programs and projects.

Missouri nonprofits can tap into a wide network of funding sources, including federal programs, private foundations, associations, and corporate sponsors. Here’s a breakdown of available grants:

  • Private funders: Private foundations offer the majority of funds in Missouri, with over 79 grants available, focusing on ecosystem restoration and environmental conservation.
  • State and Local Governments: The state of Missouri offers 25 grants, primarily for recreation, agriculture, and farming.
  • Corporate Funders: Corporate foundations support 21 grants, focusing on children’s mental health and public safety.

While government grants provide large awards, keep in mind that they require substantial compliance.

To maximize your chances of success, it's important to apply for grants in Missouri at the right time. According to current data, Q1 is the best time to submit applications, with 33.7% of grant deadlines falling during this quarter. Q2 and Q4 follow behind, accounting for 26.8% and 20.8% of grant deadlines, respectively. However, Q3 is the slowest, with only 18.7% of grants accepting applications. It is important to keep this data in mind when planning your annual grants strategy.

Grant funding in Missouri has greatly increased over the past several years. IRS funding reports indicate that the total grant funding in Missouri surged from $3.7 billion in 2021 to $4.5 billion in 2022. This marks a 22.12% increase in funding for Missouri. The largest areas for funding included single-organization support, professional societies and associations, and alliance/advocacy organizations. The top-funded counties in Missouri during this time were St. Louis County, Jackson County, and St. Louis City.

Finding the right grant can be overwhelming, but Instrumentl streamlines the grant discovery process by identifying specialized grants that align with nonprofit missions in Missouri. Beyond tracking the latest opportunities, the platform also sends deadline reminders, organizes multiple applications at once, and analyzes funder-giving trends to improve success rates.

If you are interested in finding foundation grants, see how Instrumentl can help.

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