Search Through Addiction and Substance Abuse Grants in the U.S.

Grants for addiction and substance abuse programs.

200+

Available grants

$47M

Total funding amount

$100K

Median grant amount

Addiction and substance abuse grants provide critical funding for nonprofits addressing prevention, treatment, and recovery efforts. These grants support programs focused on education, mental health services, and community outreach, helping to combat the devastating effects of addiction and improve individual and public health outcomes.


Search Instrumentl's Addiction and Substance Abuse Grants Database


Find 200+ active grants with over $47M available for nonprofits tackling addiction challenges. Explore private, corporate, and government funding options tailored to your mission. Track deadlines, gain funder insights, and grow your impact with Instrumentl's comprehensive tools.

Last updated: July 7, 2025. Next update: August 3, 2025.

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Grant Insights : Addiction and Substance Abuse Grants

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Addiction and Substance Abuse Grants grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

100+ Addiction and Substance Abuse Grants over $25K in average grant size

86 Addiction and Substance Abuse Grants over $50K in average grant size

28 Addiction and Substance Abuse Grants supporting general operating expenses

200+ Addiction and Substance Abuse Grants supporting programs / projects

2,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Environment

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Addiction and Substance Abuse grants?

Most grants are due in the third quarter.

Q1
26.2%
Q2
25.2%
Q3
27.6%
Q4
21.0%

Typical Funding Amounts

What's the typical grant amount funded for Addiction and Substance Abuse Grants?

Grants are most commonly $100,000.

Min.
Median
Average
Max.

Frequently Asked Questions

What types of nonprofits can qualify for Addiction and Substance Abuse grants?

Nonprofits who want to win grants for addiction and substance abuse are usually organizations focused on prevention. They also likely provide treatment, harm reduction services, and recovery support. The funders offering these grants care about programs that serve at-risk populations. This includes low-income communities and individuals impacted by the opioid crisis. The grants you see will require your organization to have a 501(c)(3) charitable status.

Grants for addiction and substance abuse prevention typically have the highest concentration of deadlines in Q3, with 27.6% of grant deadlines falling in this period. If you're planning to apply, consider prioritizing your applications around this time to maximize opportunities. Conversely, the least active period for grants in this category is Q4.

Why are Addiction and Substance Abuse grants offered, and what do they aim to achieve?

Addiction and substance abuse grants are offered to nonprofit programs that focus on addiction prevention, harm reduction, and long-term recovery to oppose the detrimental effects of the disease on society. Over 200 grants are available, with more than $87.1 million in funding for nonprofit groups that address addiction challenges.

Funding for addiction and substance abuse grants varies widely, with award amounts ranging from a minimum of $750 to a maximum of $7,167,816. Based on Instrumentl’s data, the median grant amount for this category is $100,000, while the average grant awarded is $359,098. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Who typically funds Addiction and Substance Abuse grants?

Of the $87.1 million available, most comes from private funders. In addition, there are many federal and state/local government funders. Some of the key funders who support addiction prevention services are the US Department of Justice, followed by a lot of state-level organizations like the Kentucky Opioid Abatement Advisory Commission and other community health foundations. On the private side of grant funding, grantors include Inasmuch Foundation, Humana Foundation, and more.

What strategies can nonprofits use to improve their success rate for Addiction and Substance Abuse grants?

A carefully planned approach is needed in order to successfully win grants for substance abuse as well as addiction programs. Funders look for organizations that show a clear effect and align with the priorities of funders. These organizations also have strong community support. To greatly increase your chances of success, concentrate on all of these key areas.

  • Forge completely meaningful partnerships – Collaborate closely with all healthcare providers, community organizations, and fellow nonprofits to strengthen your proposal and show a greatly united effort.
  • Share your story using data by collecting statistics and success stories that depict the effectiveness of your programs. Some funders want to see effect that can be quantified.
  • Offer an exhaustive financial plan – Show responsible financial management and present a budget detailing how each and every grant dollar will be allocated.
  • Every funder favors organizations showing an undergoing vision. Organizations should show complete sustainability. Describe how your program will be supported once the first grant money is used up.

Visit our resource for a complete, step-by-step guide on how to find and apply for many grants. Find grants for nonprofits with a guide.

How can Instrumentl simplify the grant application process for Addiction and Substance Abuse grants?

Instrumentl simplifies the grant application process by offering standards that helps nonprofits discover relevant funding opportunities and analyze funder-giving patterns. The platform's automated alerts ensure deadlines are never missed, while detailed funder insights help organizations modify their applications to align with grantor priorities. Discover how Oasis–A Haven for Women and Children cut their time spent on grant research by 83%.